Phylonix Pharmaceuticals received a $500,000 NSF Phase II SBIR grant to evaluate the toxic effects of industrial chemicals on human organ development in zebrafish. Preliminary data show a correlation between zebrafish results and mammalian findings.
New research symposium in Perspectives on Politics examines the complex politics of HIV/AIDS in seven countries, highlighting key findings on state action, civil society mobilization, and their consequences. The symposium provides empirical and theoretical claims on the pandemic, shedding light on the diverse impact of HIV/AIDS on rela...
A new study published in BMC Medicine found that HIV prevalence in Andhra Pradesh's Guntur district is 1.72%, significantly lower than the official estimate of 4.3% for the entire country. The study estimated 45,900 individuals with HIV in Guntur district, highlighting potential overestimation of HIV burden in India.
Researchers at Mayo Clinic Cancer Center have led efforts to test new therapies in multiple myeloma, improving effectiveness and reducing toxicity. Studies show high response rates with lenalidomide and bortezomib, and a synergistic effect when targeting both tumor cells and microenvironment.
A study published in the Proceedings of the National Academy of Sciences reveals that the brain processes pitch in Mandarin Chinese music before processing semantics in language. This finding highlights why people with cochlear implants struggle to understand tonal languages like Mandarin.
Researchers found that older men diagnosed with localized prostate cancer who received treatment lived significantly longer than those who didn't receive treatment. After accounting for differences, the study discovered a 31% lower risk of death in patients who underwent surgery or radiation therapy.
The production of frankincense is declining in the Horn of Africa due to intensive tapping, which diverts carbohydrates from reproductive organs. The study suggests that less intensive tapping procedures and rest periods are needed to ensure sustainable production.
Researchers at UCL and Imperial College London found that positive sounds like laughter trigger a brain response similar to smiling. This response occurs in the premotor cortical region, preparing facial muscles for laughter, and may play a role in building strong bonds between individuals.
A meta-analysis of 12 randomized clinical trials found that folic acid supplementation does not decrease the risk of coronary heart disease or stroke among people with a history of vascular disease. The study suggests that alternative strategies, such as smoking cessation and lipid reduction, are more effective in preventing cardiovasc...
Scientists at Cornell University have discovered a panel of 23 protein biomarkers in cerebrospinal fluid that can identify patients living with Alzheimer's disease. The biomarkers, known as a 'fingerprint,' were validated through autopsy-proven tests and showed high sensitivity and accuracy.
Researchers created hairpin-shaped RNA molecules that can differentiate between riboswitches in on and off states. These aptamers could help find new antibiotics by binding to the switches of pathogens, blocking essential protein synthesis.
Researchers found that high-performing hospitals had little difference in mortality rates for common conditions like heart attack and pneumonia. The study suggests that current quality measures are insufficient to accurately reflect patient outcomes, highlighting the need for new measures linked to clinical outcomes.
A new study reveals that coral reefs are experiencing abnormal die-off rates, unlike anything seen in the past 11,000 years. The frequency of reef disturbances was at least an order of magnitude less than today's levels, according to Associate Professor John Pandolfi.
AkaRx Inc. presents Phase I clinical data of AKR-501, a TPO receptor agonist that mimics the effect of thrombopoietin to stimulate platelet production, with a 50% increase in platelet count in healthy volunteers. The results suggest potential for safe and effective treatment of thrombocytopenia in various diseases.
Researchers used satellite imagery and radar sensors to study Pacific walrus habitats in the Bering and Chukchi seas. They found that walruses prefer medium-thickness first-year ice, which is critical for their survival and way of life.
A long-term ecological study of stream chemistry in Appalachians shows unexpected changes due to reduced sulfur emissions from acid rain. Researchers are seeing rising amounts of dissolved carbon dioxide in streams, which could impact the forest ecosystem and carbon balance.
A study found little difference in death rates for common conditions at high and low-performing hospitals, suggesting that current measures may not accurately predict patient outcomes. The authors call for more tightly linked measures to improve health care quality.
A clinical trial combining bortezomib with Doxil has shown promising results in treating relapsed or refractory multiple myeloma, a type of bone marrow cancer. The combination treatment demonstrated a better response rate compared to standard therapy alone, with a median time to progression of 9.3 months.
Scientists have discovered a unique, mouse-sized land animal in New Zealand, which challenges the theory that birds evolved without competition from land mammals. The discovery also sheds new light on climate change in the region, indicating a massive shift from warm and wet to cool and dry conditions.
The Cassini spacecraft has imaged the tallest mountains ever seen on Saturn's moon Titan, with peaks reaching nearly a mile high. The mountains are topped with bright, white material that may be methane or other organic 'snow,' suggesting a unique geology and potential for life.
A University of Washington-led team has identified a mutated form of the Palladin gene as the cause of familial pancreatic cancer. The discovery reveals that this genetic abnormality causes cancer cells to move abnormally, invading surrounding healthy tissue.
The study found that online shoppers can reap big benefits from shopping on price comparison sites, including strategies to exploit targets of opportunity and compare services beyond prices. Retailers also use these sites to their advantage, with fierce competition driving price wars and collaborations to raise prices.
Scientists have deciphered the meaning behind mysterious faces on South Pacific artifacts, revealing that they may represent sea turtles. The research, published in the Cambridge Archaeological Journal, suggests that these ceramic portraits and wooden bowls display ideas about human origins and the divine.
An observational study found that elderly men who received treatment for localized prostate cancer survived significantly longer than those who did not. The study suggested a reduced risk of mortality associated with active treatment in the elderly Medicare population.
A University of Colorado at Boulder researcher has designed compact vortex generators inspired by cephalopods, enabling more precise maneuvering and docking of underwater vehicles at low speeds. The technology may also be used to guide tiny capsules through the human digestive tract for disease diagnosis and medication delivery.
Research found that individuals with schizophrenia are more likely to have multiple chronic health conditions, including cardiovascular and neurological diseases. A third of those with schizophrenia had three or more physical health conditions, highlighting the need for integrated care.
A study of SEER-Medicare records found that surgery or radiation therapy for early-stage prostate cancer increased lifespan in men between 65 and 80 years old. Treatment was associated with a 30% lower risk of death compared to observation, even for elderly men with low-risk disease.
Scientists at the University of Illinois have discovered that a combination of ozone, high-intensity ultrasound, electrolyzed water, irradiation, and temperature is most effective in reducing E. coli 0157:H7 pathogens to meet FDA standards.
Researchers found that lightning fires in Appalachian forests can deter the encroachment of shade-tolerant hardwoods, such as red maples. This natural mechanism can aid in the regeneration of oak forests, which are approaching extinction due to human alterations and fire suppression.
According to a study in JAMA, approximately 50 million US residents younger than 65 spend more than 10% of their family income on healthcare, up from 37.8 million in 1996. The researchers estimated that 17.1 million insured persons were underinsured, with limited financial protection from high out-of-pocket costs.