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Science News Archive July 2006


Page 1 of 13

Identifying Piwi's partners

Researchers have identified Piwi's partners in gene silencing pathways using small RNAs in Drosophila. This finding introduces a novel pathway of gene silencing, leveraging the association of Piwi with specific small RNAs called rasiRNAs.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateJul 31, 2006

Paying physicians to recruit patients into trials: The ethical concerns

Recruitment incentives have grown due to competition among research sponsors, offering substantial finder's fees. This raises concerns about physician judgment, patient safety, and public trust in clinical research. The issues cannot be resolved by sanctioning individuals, but rather require broader institutional and regulatory reform.

SourcePLOS·JournalPLOS Medicine·DateJul 31, 2006

Abnormal pattern of brain development in premature babies

A study of premature babies found that their brain development follows an abnormal pattern, with the surface area growing faster than the volume. The rate of growth is critical in predicting whether a child will experience delayed development. The more premature and male the baby, the slower the growth rate and higher the risk of delay.

SourcePLOS·JournalPLOS Medicine·DateJul 31, 2006

Thrombosis in children with leukaemia

A recent study has found that thrombotic complications occur in 5.2% of children with leukaemia, with the highest risk during antileukaemic therapy induction phase. The researchers have identified several factors associated with an increased risk of thrombosis and explored the role of genetic determinants.

New, shorter TB treatments could advance TB control

A new study suggests that shorter TB treatment courses of just 2 months could reduce new cases and deaths by 13% and 19% respectively. This would free up resources to improve detection efforts and potentially lead to greater impact on TB control. Implementing such treatments earlier than planned in 2012 could yield even more benefits.

SourcePLOS·JournalPLOS Medicine·DateJul 31, 2006

MicroRNA processing and cancer

Drosha activity plays a fundamental regulatory step in microRNA processing. Blocking this enzyme can suppress miRNA production in cancer cells. This discovery may lead to novel therapeutic strategies for treating cancer by understanding the molecular events of carcinogenesis.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateJul 31, 2006

Teens and smoking: Why cessation interventions should start after the first puff

A study found that symptoms of nicotine dependence can take hold before regular smoking in some cases. This information is crucial for developing effective intervention programs for young smokers. Experts emphasize the need for stronger public health efforts to prevent youth from starting smoking in the first place.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateJul 31, 2006

Researchers develop blood test to detect lung cancer

Researchers at the University of Kentucky have developed a blood test to detect lung cancer in early stages, showing 90% accuracy in predicting non-small-cell lung cancer. The test identifies the body's immune response to tumors and could become the first blood test to predict cancer since the PSA test was introduced.

SourceUniversity of Kentucky·JournalJournal of Thoracic Oncology·DateJul 31, 2006

Treating medically unexplained symptoms

A study found that patients with somatization syndrome incorrectly remember the likelihood of medical explanations for their symptoms. Doctors can reduce this bias by asking patients for summaries about what they've been told, benefiting both patients and the healthcare system.

SourcePLOS·JournalPLOS Medicine·DateJul 31, 2006

Shorter tuberculosis therapies could lead to substantial reductions in cases and deaths

A new study found that shorter tuberculosis therapies could produce dramatic benefits at the population level by reducing transmission and improving patient outcomes. The research suggests that a two-month regimen could double or triple current rates of decline in new cases and deaths, leading to total reductions of up to 40%.

Health-care workers' SARS protective clothing systems

A Queen's University study compares two recommended protective clothing systems for health-care workers and found that one leaves workers prone to contamination at their forearms, wrists, hands, and necks. The more elaborate ensemble offers superior protection but is time-consuming to don and remove without errors.

SourceQueen's University·JournalCanadian Medical Association Journal·DateJul 31, 2006

Researchers aim to give nurses a lift

Researchers found that nurses experience debilitating low back pain, especially in orthopedic and ICU settings, with 65% of orthopedic nurses developing the condition. Providing access to mechanical lifting devices and redesigning hospital rooms could help prevent such injuries.

SourceUniversity of Alberta·JournalJournal of Advanced Nursing·DateJul 28, 2006

New genetic model for Parkinson's disease

Researchers have created a new genetic model for Parkinson's disease using mice with a deleted TFAM gene, which mimics the human condition. The study shows that dopamine-producing nerve cells in the brain stem degenerate slowly, similar to humans with Parkinson's disease.

SourceKarolinska Institutet·JournalProceedings of the National Academy of Sciences·DateJul 28, 2006

MIT researchers watch brain in action

Researchers at MIT's Picower Institute for Learning and Memory have developed a state-of-the-art imaging system that allows them to directly visualize molecular activity within individual neurons in the brain of live animals. This breakthrough enables the observation of changes in neuronal activity in response to environmental stimuli,...

Role of protein in immune response may aid HIV research

Researchers at Indiana University School of Medicine – Northwest propose that a family of proteins producing PGLYRP can be used to develop medications for HIV/AIDS patients. These proteins appear to be the front line in defending the body from infection, mounting a defense long before the body's main immune system responds.

SourceIndiana University·JournalJournal of Biological Chemistry·DateJul 28, 2006

Onchocerciasis treatment reduces prevalence and intensity by 38 percent

Researchers from Hospital Clínic de Barcelona found that a 8-year Ivermectin treatment reduced onchocerciasis prevalence by 38.4%, while incidence of disease decreased by 2.6 times in children aged 0-4. The study, financed by the Spanish Agency and WHO, marks a significant step forward in combating river blindness.

SourceIDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer·JournalTropical Medicine & International Health·DateJul 28, 2006