Advances in biology are hindered by obstacles such as dwindling National Institutes of Health budgets and overly burdensome regulatory requirements. The Association of American Medical Colleges has outlined key recommendations to promote translational research, including increased investment in medical schools and teaching hospitals.
A new study published in PLoS Medicine suggests that delivering rheumatoid arthritis drugs directly into the central nervous system improves treatment outcomes. Researchers found that blocking a protein called p38 with spinal cord administration reduced inflammation, arthritis, and joint destruction in arthritic rats.
Rhesus monkeys display neonatal imitation, reproducing human tongue protrusion and lip smacking after watching experimenters perform similar gestures. The study suggests that imitation may have evolved earlier in the primate tree than previously thought.
A study found that maternal drinking during early pregnancy is linked to a higher risk of alcohol disorders in children, with increased exposure associated with difficulties in thinking, learning, and memory. The study suggests that in utero exposure to alcohol may predispose individuals to early onset of alcohol disorders.
Rising carbon dioxide levels pose unprecedented risks to climate change, as evidenced by an 800,000-year Antarctic ice core record. Human activity has increased CO2 beyond natural ranges, raising concerns about future sinks' effectiveness.
A study by UCSD researchers shows that the central nervous system can sense and modulate inflammation in joints, reducing symptoms of rheumatoid arthritis. Blocking key signaling enzymes in the CNS resulted in decreased joint inflammation and destruction.
The article highlights the alarming rate of chronic diseases and injuries in Latin America and the Caribbean, with seven out of ten deaths attributed to these causes. The authors argue that lack of funding for health research is hindering efforts to address this crisis.
A new study suggests that higher levels of dopamine D2 receptors may provide a protective effect for those most at risk of developing alcoholism. The research found that these receptors, involved in emotional reactions and cognitive control, are elevated in the brains of participants with a family history of alcoholism.
Research supported by NIDA shows that prevention programs in middle school can reduce methamphetamine abuse among rural adolescents. The study found significant effects on both lifetime and past-year methamphetamine abuse, with a relative reduction of 65% compared to controls.
Researchers found a strong decline in lead levels in otters' bones between 1992 and 2004, reflecting reduced emissions from car fuel. The study highlights the importance of long-term monitoring and archiving of samples, providing valuable insights into human health impacts.
A revised dinosaur census by University of Pennsylvania scientist Peter Dodson estimates that 71% of discoverable genera are still awaiting discovery. The researchers predict that new discoveries will decline sharply in the early 22nd century, but a child born today can expect a fruitful career in dinosaur paleontology.
Nearly all U.S. children aged 12-17 years were exposed to tobacco use through movie advertisements televised in 2001-2002. The study analyzed 216 movie trailers, finding that 95% of young people saw at least one trailer with images of tobacco use.
A new study finds that both normal-weight and overweight individuals underestimate calorie content of larger meals. To improve weight loss estimates, consider doubling initial meal size estimates or estimating calories item-by-item. Meanwhile, virgin olive oil rich in polyphenols has been shown to increase 'good' cholesterol levels and...
Researchers argue that emotions, rather than reason, drive public distrust in institutions. The study reveals that concerns about risk are directly linked to lack of knowledge and emotional dread. Building trust requires transparency and reporting back after public consultations.
A US military hospital in Iraq treated 85 children from January 2004 to May 2005, with 56% having traumatic injuries. The experience highlights the need for hospitals near battlefields to prepare for treating civilians, including children.
The article highlights the importance of reliable estimates of global demand for an HIV vaccine in achieving various policy objectives. These objectives include convincing governments and industry to invest more in research and product development, guiding government planning of HIV vaccination programs.
Researchers developed a new, simple, and accurate dipstick test to identify the cause of bacterial meningitis outbreaks in Africa. The test uses patient spinal fluid and can determine the presence of four common meningococcus groups, paving the way for targeted treatment decisions.
Researchers found that anticipation can fire up two brain regions - amygdala and hippocampus - even before the event occurs, strengthening memories of disturbing events. This study has important implications for treating conditions like PTSD and social anxiety.
Scientists found that global warming accelerates springtime flowering, but CO2 and nitrogen deposition have opposing effects on wildflowers and grasses. The overall timing of plant growth is delayed under elevated CO2.
Research suggests that older fathers are more likely to have autistic children, with a significantly increased risk compared to younger fathers. The study, which analyzed data from over 318,000 individuals, found that advancing age among fathers was associated with an increased risk of autism spectrum disorder.
Scientists found that global changes may alter the delicate balance of species coexistence by changing the timing of plant activity. Climate change accelerated springtime flowering of all species, but elevated carbon dioxide and nitrogen deposition caused wildflowers to flower earlier while grasses delayed their blooming.
Researchers found that small-town and rural school-based intervention programs significantly reduced short-term and lifetime methamphetamine use among adolescents. These findings suggest that brief but effective prevention programs can be effective in addressing the growing methamphetamine problem among teens.