Breathing for better lung health
A study by UNC researchers found that normal breathing's rhythmic motion regulates mucus clearance, promoting lung health in CF patients. This rhythm also re-hydrates airways, accelerating mucus removal.
Science News for April 14, 2007
Blame the brain for high blood pressure
Scientists at the University of Bristol have found that inflammation caused by trapped white blood cells can obstruct blood flow to the brain, leading to poor oxygen supply. This discovery suggests a new mechanism for high blood pressure, with potential therapeutic targets for treatment.
Investigational cancer drug targets critical proteins
Researchers discovered that an investigational cancer drug selectively kills cancer cells due to its affinity for a modified version of heat shock protein 90. The modification, called acetylation, allows the drug to target and block the activity of this protein, promoting cell survival.
Information processing in the central nervous system: the signalling system controlling movement
Research reveals how interneurones process information from senses and brain to control movement, with persistent sodium current playing a critical role. Abnormal regulation of this current may impair motor command integration, affecting normal movement patterns.
ATR checkpoint-activating DNA structure
Researchers have identified a minimal DNA structure that activates the ATR-mediated DNA damage checkpoint in a cell-free system. This discovery enables precise control and quantitative probing of checkpoint signaling responses.