Research-backed stress relief solutions, such as emWave and StressEraser, have proven benefits through double-blind clinical trials. The American Institute of Stress has recognized these programs for their innovation and effectiveness in reducing stress.
Researchers at Thomas Jefferson University have found that nearly all recurrent prostate cancers resistant to hormone therapy activate a signaling protein called Stat5, making it a potential drug target. The convergence of two biological pathways may also contribute to the development of aggressive hormone-resistant tumors.
Research reveals antisense transcription of the Hox miRNA locus generates a novel miRNA precursor, mir-iab-8, which represses Hox gene targets, resulting in homeotic phenotypes. Additional antisense miRNAs identified in Drosophila and mammals may contribute to diversification of miRNA function.
A new study by Cambridge University found that doctors treating life-threatening emergencies like allergy attacks often give the wrong dosage of adrenaline because of confusing labelling. The researchers discovered that this can lead to dosing errors and delays in administering the drug.
Researchers have identified a key gene, 14-3-3zeta, that enables lung cancer cells to survive on their own. Silencing this gene has been shown to inhibit the growth and survival of lung cancer cells, making it a potential target for selective anti-cancer drugs.
A recent study found that suppressing slow-wave sleep in healthy young adults significantly decreases their ability to regulate blood-sugar levels. After only three nights of selective slow-wave sleep suppression, subjects became less sensitive to insulin, resulting in reduced tolerance to glucose and increased risk for type 2 diabetes.
Researchers at the Salk Institute found that early-stage breast cancer cells with high motility pose an increased risk of metastasis. These cells can wander along milk ducts and seed new tumors within the same breast, suggesting a need for earlier intervention.
Researchers discovered that uridine residues are added to the 3' end of histone mRNAs, decapping and degrading them via the general mRNA decay machinery. This work represents a new mechanism regulating the half-life of specific mammalian mRNA transcripts.
A study found that targeted digital mammography screening can be cost-effective for younger women with dense breasts, while conventional film mammography may be more effective for older women. Additionally, labeling epinephrine as a dose or ratio affected dosing errors among doctors.
People with restless legs syndrome are twice as likely to develop cardiovascular disease or cerebrovascular disease, according to a study published in Neurology. The risk is highest in those with RLS symptoms at least 16 times per month, where they are more than twice as likely to have cardiovascular disease or cerebrovascular disease.
The Deep Impact spacecraft is using its flyby of Earth to calibrate its instruments for the EPOXI mission, which will study comet Hartley 2. The team made observations of the moon to test the spacecraft's pointing and commanding systems.
Researchers at Ohio State University Medical Center found that serotonin and synthetic hallucinogens trigger different chemical pathways in brain cells, leading to important implications for drug development. The study's findings suggest that screening agents must also determine if the agent signals through beta-arrestin.
Researchers isolated the signal of ocean global warming by analyzing historical temperature records. Volcanic loading in Hawaii triggered earthquakes with divergent mechanisms. Climate scientists found anticorrelated precipitation patterns between China and Brazil, suggesting oceanic circulation triggers abrupt climate events.
A study published in Journal of Cosmetic Dermatology found that topical application of niacin, engineered peptides, retinoids, and photoprotective ingredients can visibly improve maturing skin. Combining these ingredients in a moisturizer magnifies benefits.
A physician-scientist is urging improved drug regulation to ensure the cardiovascular safety of non-heart drugs. This includes earlier testing and continued evaluation of drug effects post-approval.
A research team at Weill Cornell Medical College identified two genes, Pbx-1 and Prep-1, that play a critical role in regulating interleukin-10 (IL-10) production. This discovery could lead to new avenues for understanding and treating diseases such as lupus, cancer, and HIV/AIDS.
Researchers found a 40% decrease in pilot error-related mishaps between 1983-2002, attributed to enhanced training and technology. However, the study also revealed an increase in ground-related mishaps, highlighting areas for further improvement.
Research on farm women reveals an increased risk of allergic asthma associated with pesticide use. The study found a significant increase in asthma prevalence among women who applied or mixed pesticides, with some compounds like parathion linked to nearly tripled risk.
The management of glaucoma costs the US healthcare system approximately $2.5 billion per year, with glaucoma medications accounting for 38-52% of direct costs. Non-selective ß-blockers remain the most inexpensive class of glaucoma medications, while brand-name ß-blockers are consistently more expensive than their generic counterparts.
Researchers developed a mutated anthrax toxin that targets melanoma cells, with 100% of mice tolerated lethal doses. The toxin was more specific and effective than natural toxin, inhibiting angiogenesis and killing other tumors like colon and lung.
A review published in Dermatologic Therapy reveals that men need higher doses of Botox due to greater muscle mass, leading to inadequate results from under-dosing. The study suggests that larger, stronger men require more units per treatment area than slender, small-boned men.
A Phase 2 study found eltrombopag increased platelet counts in 74% of patients with low platelet counts and cirrhosis due to hepatitis C. The drug also allowed more patients to complete antiviral therapy, with 36-65% completing treatment at the lowest and highest doses.
A recent study found that patients with severe COPD who received salmeterol-fluticasone (SFC) therapy had lower mortality rates compared to those treated with tiotropium. Additionally, SFC treatment was associated with better health status and fewer patient withdrawals.
A study of 196 high myopic eyes found LASIK to be a safe and effective procedure in the long term. The results showed that 40% of patients avoided wearing glasses after surgery, while only 5% lost more than 2 lines of vision.
Research shows that exposure to violent media increases aggressive behavior in children, with over 14 scientifically documented effects on physiological and psychological well-being. Despite this, few people take action, and public policy has failed to address the issue.
A recent study found that acute allergic-like reactions to gadolinium-containing contrast injections are rare, with 74% of cases being mild. The study included over 78,000 administrations and reported no fatal reactions, supporting the safe use of these agents in patients with normal or mildly impaired renal function.
A recent study by Sanjeev Dewan, Charles Shi, and Vijay Gurbaxani found that information technology (IT) investments are substantially riskier than ordinary capital investments. This increased risk is associated with a substantial risk premium, driven in part by the lost option value of making irreversible capital investment decisions.
Researchers have made significant progress in cardiac stem cell therapy, exploring novel delivery methods and strategies to improve cell survival. These advancements aim to overcome the challenges of poor vascular supply and inflammation after a heart attack, paving the way for more effective treatments.
Researchers reveal a new, tightly regulated layer of the plant transcriptome that is controlled by the exosome complex. The study provides a genome-wide atlas of Arabidopsis exosome targets and sheds light on the mechanisms of RNA quality control in plants.
The WIN-R study found weight-based REBETOL plus PEG-INTRON improves sustained virologic response and lowers relapse rates, particularly in African-Americans with genotype 1 HCV. Weight-based dosing is also justified for very heavy patients.
Researchers at Hebrew University of Jerusalem found that subliminal exposure to a national flag image can moderate political attitudes, voting intentions, and actual voting in general elections. The studies showed that participants exposed to the subliminal message tended to adopt more centrist views and voted for central parties.
Researchers at Tufts University found that brain-derived neurotrophic factor (BDNF) is critical for mediating satiety in adult mice. Mice with deleted BDNF genes ate more and became heavier, highlighting the protein's role in energy balance.
A new report suggests that preserving deep-sea biodiversity is crucial for the health of oceans. Researchers found that sites with a higher diversity of nematode worms support exponentially higher rates of ecosystem processes and increased efficiency. This study highlights the importance of protecting the world's most critical ecosystem.
Researchers developed a fast-acting antidote to cyanide poisoning that works in under three minutes and can be taken orally, giving emergency responders more time to respond. The new antidote has been tested on animals and shows exceptional effectiveness.
The Pourquié Lab has linked Beta-catenin to the process of somite formation, a critical step in vertebral column development. Increasing Beta-catenin levels alters mesoderm maturation and corresponds with oscillations of the segmentation clock.
A study by Indiana University researchers found that receiving primary care during cancer treatment improves cancer survival rates, especially in lung cancer patients. Primary care utilization increased median survival rates by over fourfold, highlighting the importance of comprehensive care for whole-person health.
A new study found that adult male chimpanzees, like females, have distinct core areas for foraging alone and show high site fidelity. They remain faithful to the area in which they grew up, even 20 years after their mother's death.
The study showed significant benefits of Avastin with Taxol in treating metastatic breast cancer, nearly doubling the time between chemotherapy initiation and tumor progression. This achievement demonstrates Avastin's potential as an antiangiogenic agent in breast cancer therapy.
A team of biologists has developed a model mapping the control circuit governing a whole free-living organism, allowing for accurate prediction of cell dynamics and adaptation to environmental stresses. The study, based on Halobacterium salinarum, provides insights into how cells make stable decisions in response to their environments.
Researchers warn that powerful molecular tools in cancer research can lead to misleading conclusions due to the complexity of generated data. The team highlights the need for better understanding of the challenges in analyzing these genomic and proteomic technologies.
Researchers discovered that cone-beam breast CT provides exceptional tissue contrast and can reduce examination time with comparable radiation dose to conventional 2D mammography. The study found well-resolved images of skin, adipose, and glandular regions, as well as clear detection of microcalcifications within cancers.
Researchers have developed a key small molecule inhibitor targeting 'virulence factors' used by bacteria to thrive, offering an alternative means of stopping TB, leprosy, and other bacterial illness. The findings highlight a paradigm shift in infectious disease research beyond antimicrobials like antibiotics.
Researchers at Baylor College of Medicine identified a new mechanism, called Fork Stalling and Template Switching, which causes DNA copy number variation. This process stalls when there is a problem with the DNA, switching to a different template before returning to the original area.
The Baumann lab has identified the long-sought telomerase RNA gene in a single-cell research model, providing a critical tool for studying telomerase in human cells. This breakthrough sheds light on the correlations between telomere shortening and various diseases, including cancer and coronary heart disease.
Researchers found a connection between TRAIL's receptor and cancer susceptibility, as well as inflammation and cancer via TRAIL. Mouse models with TRAIL receptor knock-out developed larger tumors after exposure to carcinogens or radiation.
The NIEHS is awarding a total of $6.8 million to three new research centers called DISCOVER, which will bridge the gap between basic research and clinical treatment of diseases caused by environmental factors.
Researchers at Imperial College London have discovered a mechanism that prevents the immune system from regulating itself properly, leading to allergic reactions. The new finding highlights the importance of regulatory T-cells in maintaining immune tolerance.
A large clinical trial found that bevacizumab significantly prolongs progression-free survival for women with recurrent breast cancer when combined with chemotherapy. The study showed a doubling of delay in worsening of the disease and improved remission rates compared to chemotherapy alone.
Naumann co-authored paper 'Modular Verification of Higher-Order Methods with Mandatory Calls Specified by Model Programs' recognized for its precise and modular technique for specifying callbacks in object-oriented software frameworks. The 22nd annual OOPSLA Conference, held in Montreal, Canada, also featured industry experts and keyno...
Researchers found that people with high triglycerides were 2.7 times more likely to have a large artery atherosclerotic stroke than those with low levels. Non-high density lipoprotein cholesterol was also linked to an increased risk of this type of stroke.
A new study published in PLOS Biology found that the number of X chromosomes determines the sex of a fruit fly embryo, contradicting previous findings. The researchers discovered that only two X chromosomes can produce a signal to feminize the embryo during a specific stage of development.
A new clinical trial results in a proof-of-principle for personalized molecular medicine, with the potential to treat muscular dystrophies and other disorders. The treatment uses an 'exon-skipping' approach to restore dystrophin protein production in muscle tissue.
An international team of astronomers has successfully detected and monitored the polarized light scattered in an exoplanet's atmosphere for the first time. The study reveals that the exoplanet, HD189733b, has a swollen atmosphere with particles scattering blue light, similar to Earth's atmosphere.
A new study suggests whale shark populations are healthy and growing in Ningaloo Reef due to regulated ecotourism. The research used computer-assisted photographic identification to track individual sharks and found two-thirds of the sharks were repeat visitors.
A study published by the American Academy of Neurology found that stimulating hand muscles using low-amplitude vibration can help treat musician's dystonia. The therapy, which lasts just 15 minutes, has been shown to restore a more normal brain response in people with the condition.
Researchers at UC-San Diego have developed a modified protein that can block excessive scar tissue growth in the liver, stopping its progression and even reversing some cell damage. The peptide has shown promising results in animal studies, opening new possibilities for treating conditions like cirrhosis of the liver.
Synaesthetes often perceive the world as having a consistent and permanent vision. They may feel strongly about their experiences, which can affect preferences and perceptions. Research by Alicia Callejas Sevilla at the University of Granada explores various forms of synaesthesia.
A nationwide collaborative study found that emergency department patients who underwent alcohol screening and brief intervention reported lower rates of risky drinking than those who received only written information. The study enrolled over 7,751 patients and showed that more than one-fourth exceeded low-risk drinking limits.
Hebrew University researchers received prestigious EU research grants to advance their careers and tackle groundbreaking projects. The five winners will focus on innovative fields such as dormant bacterial spores, group theory, neurophysiological changes, planetary formation, and protein-modulating drugs for cancer and AIDS.
A new study found that expanding health coverage to people without it leads to demonstrable improvements in health, particularly for those with heart disease or diabetes. Uninsured adults who gained Medicare coverage had 10 fewer major cardiac complications by age 72 compared to expected.