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Science News for July 14, 2007


On target

Researchers have identified IL6 as a protein that stimulates tumor growth when activated by Ras, leading to increased blood vessel formation. Suppressing IL6 activity has shown promising results in fighting tumor formation in preclinical models.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateJul 14, 2007

Potential new target for cancer found

Researchers at Duke University Medical Center have discovered that the overactive Ras gene is responsible for above-normal secretion of interleukin-6 (IL-6), which drives tumor growth. Inhibiting IL-6 production reduces new blood vessel creation, crucial for tumor development and nourishment.

SourceDuke University Medical Center·JournalGenes & Development·DateJul 14, 2007