A new study found that treatment with ibuprofen is associated with a significantly slower rate of decline in lung function in children and adolescents with cystic fibrosis. The study showed a 29 percent reduction in loss of lung function compared to those who did not use the anti-inflammatory drug.
Scientists are discovering that aquatic nanoparticles influence natural and engineered water chemistry differently than similar materials of a larger size. The review considers nanoparticles formed by natural processes in water and as unintended consequences of human activity, such as mining or water treatment.
CONRAD has received a $28.5 million grant from the Bill & Melinda Gates Foundation to develop microbicides for HIV prevention, supporting combination microbicide research and testing of novel candidates.
Research by Purdue University associate professor Karen Fingerman found that a majority of parents and children reported positive changes in their relationship as parents transitioned to old age. Despite declining health, many parents felt appreciated and nurtured, while children expressed gratitude for increased help from their parents.
Research by Arizona State University scientists reveals that helium-3/helium-4 ratios can be used to identify areas with high geothermal resource potential. Analyzing samples from over 60 hot springs and shallow wells in the Basin and Range province, they discovered a correlation between helium ratios and deformation rates.
A University of Iowa study found that even when both partners are highly educated and earn a significant income, women tend to sacrifice their careers for their husbands' promotions. The research suggests that entrenched gender roles contribute to this phenomenon.
Researchers from the University of the Basque Country have published two articles in Nature on their findings about the atmosphere, climate and weather patterns of Venus. The studies revealed the presence of a double vortex at the South Pole, which is similar to those found on Earth's polar regions.
The Gamma-ray Large Area Space Telescope (GLAST) spacecraft has successfully completed two environmental tests and is now undergoing thermal and vacuum testing at the Naval Research Laboratory. The satellite will study extreme universe phenomena, including black holes and gamma-ray bursts.
Experts warn that the European Water Framework Directive lacks a comprehensive approach to monitoring and addressing chemical pollution in rivers. The current priority list of substances is deemed inadequate, and researchers advocate for prioritizing effects rather than just chemicals.
Three quarters of the universe is dark energy, a mysterious substance that repels gravity. New space missions and improved observation methods will help uncover its secrets.
Research published in PLoS Medicine highlights the high risk of HIV infection among men who have sex with men in developing countries. Targeting HIV prevention programs to reach these men is crucial to curb transmission and reduce global burden.
A recent study reveals that CMV retinitis is causing blindness in young people with HIV in the developing world, often leading to fatal outcomes. Successful management of the disease requires decentralizing diagnostic capacity and making valganciclovir medication affordable.
Bowel cancer screening has significantly reduced emergency admissions and death rates in a UK pilot study. The study found that the number of emergency operations required halved, and the number of patients dying within 30 days also fell.
A new system has been developed to classify rare lung diseases in infants, improving diagnosis and treatment outcomes. The system groups various lung diseases into distinct categories, allowing pathologists to diagnose children's lung disease more accurately.
Researchers have produced molecular chimeras by binding fullerene receptors to a fullerene molecule, forming short chains of linked nanopearls. These aggregates exhibit special binding interactions between electrons, making them promising for efficient optoelectronic components.
Researchers at MIT used fMRI to monitor brain development in rats, correcting for changes that occur during early life. The study found a key player in the changing relationship between neural activity and blood response: carbonic anhydrase.
Researchers found that abnormally folded prion protein in brain tissue does not reliably predict disease infectivity; some highly infectious samples had nearly undetectable levels of abnormal PrP. This suggests alternative mechanisms or specific conformation of abnormal PrP may be responsible for prion diseases.
A Purdue University research team captured an image of the protein gate complex that allows materials to enter cells, providing insights into disease mechanisms. The discovery may lead to more effective treatments for diseases like cancer and cystic fibrosis by inhibiting or activating this mechanism.
Researchers have discovered 156 new likely imprinted genes in the human genome, including those linked to cancer, diabetes, and autism. The findings offer clues to better disease prevention and management.
Researchers have successfully implemented community-based projects to address cancer disparities among African-American and Hispanic communities, and Navajo Nation population. The initiatives improve data collection, provide insight into social factors, and lead to sustained health improvements.
Researchers have developed a powerful tool to systematically map out pathways and subpathways contributing to inflammation. This study has led to the creation of customized panels for analyzing genetic variations in inflammation pathways for European and African descent populations.
Patients report feeling uncertain about out-of-hours primary care services, with concerns over appropriateness and responsiveness. Staffing issues and slow handling times are also cited as key problems, highlighting the need for better patient experience monitoring.
Researchers from the University of Bayreuth and Helmholtz Centre for Environmental Research found that Alpine summit vegetation is becoming increasingly homogenized due to climate change. This has led to an increase in species diversity within individual areas, but a decline in regional biodiversity across ecosystems.
A study by Dr. Groesbeck Parham found that 90% of HIV-infected women presenting for antiretroviral therapy harbor cervical cell abnormalities, increasing the risk of cervical cancer. Access to screening and treatment is crucial to prevent this life-threatening condition in women living with AIDS.
A new study reveals HIV epidemic among men who have sex with men (MSM) is widespread and severe in low- and middle-income countries. MSM are 19 times more likely to be infected than the general population, with rates up to 100 times higher in some countries.
A recent study found that chronic alcohol consumption by lung donors promotes scarring and airway injury after transplantation. The research, published in the American Journal of Respiratory and Critical Care Medicine, raises questions about human lung donors with a history of alcohol abuse.
Researchers at Stevens Institute of Technology are developing functional polymers modified surfaces that can prevent bacterial adhesion and sensitize formed biofilms for antibiotic treatment. This project aims to combat the fourth leading cause of death in the US, hospital-acquired infections and diseases.
Direct-to-consumer genetic testing poses risks of misleading patients and physicians due to lack of regulation. Physicians recommend consulting with doctors before ordering tests, as results may not be clinically valid or accurately interpreted.
A team of researchers at the University of Michigan has developed a nano-scale voltmeter that can measure electric fields deep within cells. The device, which is 1,000-fold smaller than existing voltmeters, reveals surprisingly high electric field strengths in cytosol, challenging conventional wisdom about cellular processes.
A retrospective case note review of 1000 patients found that 8.7% experienced at least one adverse event, with many preventable, and led to extended hospital stays or permanent disability
A new test vaccine against Japanese encephalitis virus has shown promising results, with a high seroconversion rate and good safety profile. The vaccine is considered at least as effective as the existing licensed vaccine, making it a potential candidate for use in travelers and children in endemic areas.
Researchers have found that less carbon is transported to deep water during natural plankton blooms than during the rest of the year, suggesting the Biological Pump leaks. This discovery challenges ocean fertilization schemes, which ignore natural processes and may not remove as much carbon dioxide from the atmosphere.
The new Chlamydia rapid test detects infection in over 4 out of 5 infected women, even without symptoms. The test can provide results in under 30 minutes and is up to twice as accurate as current tests.
The National Institutes of Health (NIH) recognizes the contributions of researchers and managers in the fight against HIV/AIDS. Since the first cases of AIDS were reported, NIH has established a comprehensive trans-NIH research effort to understand HIV biology, develop effective therapies, and prevent new infections.
A recent study by McGill researchers found that the enzyme focal adhesion kinase (FAK) is crucial for tumour progression from a pre-malignant to a malignant state in the mammary tumour system. The discovery opens up new avenues for developing targeted treatments against breast cancer.
A new study by the University of Helsinki finds that EU forests are expanding and absorbing large amounts of carbon, with an average annual absorption of 126 teragrams between 1990 and 2005. The expansion of forests in certain countries, such as Finland and Lithuania, has even more than offset national emissions.
Astronomers at the University of Illinois have discovered a stellar cradle where planets and moons are believed to form. Located 800 light-years away in the constellation Cepheus, the object is an enormous flow of shocked molecular hydrogen gas erupting from a young protostar's magnetic poles.
Research from University College London found that some of our closest extinct relatives had more in common with gorillas than previously thought. The study discovered that males continued to grow well into adulthood, leading to a significant size difference between males and females, similar to what is seen in gorillas.
A Chikungunya virus outbreak in Italy emphasizes the need for preparedness and response to emerging infectious threats as globalisation increases. The disease was fairly mild in nearly all cases, with only one reported death.
A new heart test has been developed to detect mild degrees of heart injury, enabling doctors to identify patients most likely to benefit from life-saving treatments. The test, which searches for a specific protein in the blood, could lead to fewer unnecessary hospital admissions and improved diagnosis.
Researchers discovered that blood stem cells can travel to visceral organs to perform reconnaissance missions and produce new immune cells. These cells can synthesize defense mechanisms to counter invading pathogens, indicating a more dynamic role for hematopoietic stem cells.
Researchers identified two proteins, hnRNP-H1 and SAFB-2, as potential biomarkers for disease screening in African-American men. These proteins are involved in the growth of tumor cells and may play a role in hormone-related prostate cancer progression.
A recent paper suggests that reducing carbon emissions from deforestation and degradation (REDD) could be key to addressing climate change. By including REDD in the Kyoto Protocol, developing countries can claim compensation for sustainable forest management, potentially earning $630 million annually.
Carnegie Mellon's National Robotics Engineering Center has won a $14.4 million contract to develop an advanced, autonomous unmanned ground vehicle (UGV) for the US Army. The UGV will utilize lessons learned from the successful 'Crusher' platform and incorporate latest suspension, vehicle frame, and hybrid-electric drive technologies.
Patients using out-of-hours services report feeling uncertain about the appropriateness of their calls and concerns about slow case handling. Despite this, many are happy with the quality of service once they speak to a healthcare professional.
A team from the University of Illinois identified SgrS, a 200-nucleotide-long RNA molecule, which performs two functions to regulate glucose metabolism in bacteria. The molecule binds to messenger RNA to inhibit new glucose transporter production and codes for a protein that retards existing transporter activity.
Researchers have identified potential geothermal energy resources in the northern Basin and Range province, characterized by high thermal gradients and deep permeable pathways. The discovery uses helium isotope ratios to map zones of higher than average permeability, offering a new tool for identifying geothermal energy resources.
Researchers have found that double-strand DNA breaks occur more frequently in specific regions near telomeres and centromeres, increasing the likelihood of chromosome gene swapping. This discovery may lead to a better understanding of developmental chromosome abnormalities and birth defects.
Two studies show that increasing Quitline services and offering free nicotine patches significantly increase quit rates, with over 21% of smokers quitting after intensive counseling. The added cost is offset by increased effectiveness, making these services a cost-effective way to reduce smoking rates.
Research by University of Florida scientists found that using club drugs triggers a similar chemical chain reaction in the brain as a traumatic brain injury, resulting in cell death and memory loss. The study suggests that methamphetamine use can cause irreversible brain damage.
University of Wisconsin-Madison scientists have found that a basin-wide circulation pattern drives Atlantic hurricane activity. The study reveals that Atlantic hurricanes will be more sensitive to climate changes than storms in other ocean basins, with warmer oceans indicating ideal conditions for development. Understanding this relati...
Researchers block single gene NF-êB to reverse aging in mouse skin, demonstrating that aging is a result of an active genetic program. The study sets the stage for future genetic age-intervention therapies.
Researchers have made significant progress in identifying new biomarkers for epithelial ovarian cancer, which can aid in early detection and improve treatment outcomes. The study highlights the potential of these biomarkers as therapeutic and imaging targets.
Dr. Bridges' group successfully demonstrates marker genes can be efficiently inserted into heart muscle cells in large animals using a novel surgical procedure and specially designed hardware. The approach has the potential to develop new treatments for various heart muscle diseases causing heart failure, with preliminary success showi...
A recent study found that 318 of 321 benign-appearing adrenal masses were confirmed to be clinically insignificant. The study showed no malignant adrenal lesions, even among patients with other malignancies elsewhere.
Researchers discovered JAM-C plays a critical role in maintaining peripheral nerve integrity and function. The molecule was found to be defective in nerves from patients with specific disorders, suggesting potential causes and a platform for further research.
A recent study found racial discrepancies in breast cancer tumor gene profiles, suggesting inflammation plays a stronger role in development and progression in African-American women. African-American breast cancer patients tend to have a greater prevalence of an aggressive form of cancer less likely to respond to hormone therapy.
Researchers at Mayo Clinic have developed a new imaging technology called magnetic resonance elastography (MRE) that can provide images of affected muscles with greater clarity than traditional MRI. This technology measures tissue elasticity and can detect abnormal hardening of tissues, which is a hallmark of myofascial pain syndrome.
Researchers at the University of Michigan have found two young stars with gaps in their protoplanetary disks, suggesting infant planets cleared debris. The study provides new insights into solar system formation and history.
Researchers found that patients over 60 years old, experiencing morning stiffness and groin pain, are at higher risk of undergoing total hip replacement. The study also revealed that obesity may decrease the risk of THR after three years.