Scientists at Sirtris developed potent SIRT1 activators, 1000 times more effective than resveratrol, to treat Type 2 Diabetes and age-related diseases. These findings hold promise for a new approach to treating metabolic and other diseases of aging.
A new study by University of Illinois researchers found that grape-seed extract is a viable natural alternative to synthetic ingredients for preserving meat quality in pre-cooked meals. The extract's phenolic compounds have been shown to be effective antioxidants in slowing the oxidation of fats.
Fuel cells face challenges such as membrane degradation, carbon corrosion, and platinum instability, leading to reduced durability. Researchers are working to understand the fundamental failure mechanisms and develop new materials or system approaches to mitigate these issues.
A K-State study predicts devastating economic impacts if foot-and-mouth disease were to occur in Kansas, with estimated losses of $36 million, $199 million, and $945 million for the state. The study analyzed three scenarios and found that larger outbreaks would result in longer durations and greater economic ruin.
Scientists have developed a method to control the magnetic properties of a commonly used blue dye, Metal Phthalocyanine, which could significantly improve information processing. The technique uses magnetism to regulate interactions between molecules, offering potential benefits for spintronics and quantum computing.
Scientists discovered three biological classes of malaria parasites with distinct metabolic states, including one linked to patient symptoms. The findings suggest a possible correlation between parasite behavior and disease severity.
Scientists at Jefferson Medical College have used PET imaging to observe hyperactive breast cancer genes in laboratory animals, marking a breakthrough in detecting and classifying cancer. This technology may help physicians identify breast tumors as early as possible and determine the appropriate treatment.
A study presented at RSNA suggests that CT scans can diagnose heart disease in low-risk patients, reducing hospital stays from 12 hours to just over 9 hours. This could lead to significant cost savings and improved resource utilization in emergency departments.
The study found a 121% increase in imaging exams performed on pregnant women between 1997 and 2006, with the greatest increases seen in CT exams. The researchers estimated that pregnant women are exposed to low but potentially harmful levels of radiation during these exams.
New study reveals that alcohol and tobacco use do not increase the risk of head and neck cancers in people infected with HPV16, a common strain of the sexually-transmitted virus. The findings suggest two distinct causes for these major cancers, requiring different prevention and treatment strategies.
A study by Beth Israel Deaconess Medical Center has identified the atrogin-1 gene as a key player in statin-related muscle toxicity. The researchers found that statins activate this gene, leading to muscle damage and atrophy, with potential implications for patients taking these cholesterol-lowering drugs.
Researchers at UC Davis Health System have identified a novel pathway that contributes to increased inflammation of blood vessels in type 1 diabetes patients. This finding may lead to the development of new treatments to reduce cardiovascular disease risk by controlling inflammation.
Researchers have made a breakthrough in deriving functional heart cells from human embryonic stem cells, exhibiting excitation-contraction coupling and handling calcium ions. The finding offers hope for future use of stem cell treatment in patients with end-stage disease, potentially avoiding the need for heart transplants.
A new risk prediction model for African American women has been developed and tested, providing more accurate estimates of breast cancer risk compared to the widely used Gail model. The model, known as CARE, accurately predicted the number of cancers observed in African American women in most subgroups.
A novel computer technique predicts side effects of major pharmaceuticals, including SERMs for breast cancer treatment. The approach shortens drug development and reduces costly recalls by identifying off-target proteins.
Researchers at the University of Illinois have developed a new, catalyst-free approach to create self-healing materials that can repair cracks in composite materials. The new system uses chlorobenzene microcapsules to restore structural integrity, with fracture tests showing a 82% recovery of original fracture toughness.
Using adult human stem cells, researchers found that the treated hearts contained more blood vessels and exhibited increased DNA repair activity. The study suggests that these stem cells have an instant stimulating effect on surrounding heart tissue following transplantation.
A computer model developed by Dr. David Morton is being expanded to prioritize radiation detector placement in high-risk areas, using data on smugglers' routes, materials, and methods. The goal is to detect nuclear smuggling attempts more effectively.
The UK Politics and International Studies research has been rated as world-leading according to a new report by the ESRC, PSA, and BISA. The discipline excels in areas such as political theory, electoral studies, and European Union studies.
A recent study by MIT scientists suggests that adult stem cells produced in the brain can only make limited connections, making it challenging to use them for replacement therapy. The research calls into question the potential of using adult stem cells to repair damaged brain tissue and replace lost neurons.
A study found that approximately 27% of obese gastric bypass patients weighing over 450 pounds were denied standard diagnostic imaging due to weight restrictions. This can lead to delayed diagnosis and compromised patient care.
A new automated dental radiograph matching system can reduce the task of forensic experts by up to 95% and produce matches at an average rate of less than four seconds. The system uses Phase-Only Correlation technology to align images and measure their similarity, resulting in a significant reduction in time spent on identification.
A £1.7 million project led by the University of Leeds seeks to fully sequence the DNA of G. pallida, a parasitic worm attacking potato crops worldwide. The research aims to understand its mechanisms and lead to sustainable management methods.
Researchers at NIST have shown that silicon crystals can develop cracks and breakdown under mechanical stress, contrary to conventional wisdom. The team's findings have significant implications for the design of micro-electromechanical system (MEMS) devices, which are critical components in various industries.
The newly completed map of Antarctica is a result of NASA's state-of-the-art satellite technologies, offering the most geographically accurate and high-resolution views of the continent. The Landsat Image Mosaic of Antarctica will enable researchers to better plan scientific expeditions and help scientists map various rock formations.
Computed tomography (CT) autopsies have been shown to be a sensitive tool for detecting injuries and cause of death in victims of blunt trauma. In a study comparing CT with conventional autopsy, CT accurately identified the cause of death in all 14 blunt trauma cases and five out of six penetrating wounds.
New community-associated MRSA strains have emerged, spreading amongst the public in the USA, and are now a concern for children's health. These strains produce a toxin called PVL, leading to severe infections with high mortality rates if left untreated.
Researchers developed an independent measurement system using cameras, microphones, and laser scanners to evaluate the performance of advanced collision warning systems. The NIST technology detected objects within eight-tenths of a meter from up to 60 meters away at speeds of up to 56 mph.
Two studies led by Johns Hopkins Bloomberg School of Public Health researchers suggest that HIV subtype E is more virulent than other subtypes, leading to significantly shorter survival rates in Thailand. The studies found a median survival time from infection to death of 7.8 years for Thai men, compared to 11 years globally.
A Mayo Clinic study shows cryoablation can provide durable pain relief for patients with bone metastases. Eighty percent of patients experienced significant pain reduction after the treatment, which also improved their quality of life.
Male BRCA1 and BRCA2 mutation carriers have a higher risk of developing breast cancer compared to noncarriers. A high carbohydrate diet may also promote prostate tumor growth in mice, while infection with human papillomavirus (HPV) is associated with an increased risk of head and neck cancers but does not further increase the risk when...
A systematic review of recent studies suggests PET imaging can accurately diagnose and stage lung cancer, even in early stages. The imaging modality is found to be more accurate than CT imaging for treatment decisions in non–small-cell lung cancer patients.
A study found that high-trauma nonspine fractures in older women and men are associated with low bone mineral density and an increased risk of a subsequent fracture. The researchers analyzed data from two U.S. studies and found that low bone mineral density was strongly associated with high-trauma nonspine fractures.
Researchers found that blocking blood vessel growth with an antiangiogenic agent can reduce inflammation and improve antitumor efficacy of oncolytic virus therapy. This approach may increase survival rates for patients with aggressive brain tumors.
A new molecular method can identify multidrug-resistant strains of Acinetobacter baumannii in four hours, allowing for prompt isolation and infection control measures. This rapid test has the potential to reduce transmission and improve patient management.
A team of MSU researchers found inconsistencies in China's certification and traceability systems, which can affect the quality and safety of imported goods. The experts recommend increased government oversight, training for producers and distributors, and improving labelling practices to ensure compliance with international standards
The Million Book Project has completed the digitization of over 1.5 million books, ranging from Mark Twain to Confucius, and made them available through a single web portal. The collection includes rare and orphan books in multiple languages, with the goal of making all published works accessible worldwide.
Researchers used PET/CT to diagnose and stage inflammatory breast cancer, detecting disease earlier than traditional methods. The study achieved a 95% accuracy rate in identifying cancerous areas and involved 41 women with the aggressive form of breast cancer.
A recent study has found that progesterone has limited benefits for mice with Alzheimer's symptoms, but inhibits some of estrogen's beneficial effects when taken together. The study suggests that the constant daily dosage of progesterone may be antagonizing its potential benefits.
A team of researchers has discovered a tumor-suppressor gene called Par-4 that kills cancer cells but not normal cells. The mice born with this gene live longer and have no toxic side effects, making it a potentially therapeutic application for treating cancer without harming patients.
Scientists investigate Hanford's vadose zone to understand contaminant migration and develop remediation solutions. They find complex pathways for nuclear waste travel, affecting composition and speed, impacting the environment and people downstream.
A University of Michigan study reveals that watching violent TV and playing video games significantly increases the risk of aggressive behavior in both children and adults. The research, conducted over half a century, highlights the detrimental effect of media violence on public health.
The CSIRO report found that biodiesel produced from used cooking oil can reduce emissions by up to 87%, while palm oil sourced from pre-1990 plantations can achieve an 80% emission reduction. This could lead to improved air quality and reduced health risks.
A clinical model predicting hip fracture risk in postmenopausal women was developed based on 11 clinical factors. The model was validated using data from the Women's Health Initiative and showed accuracy in stratifying risk among various ethnic backgrounds.
A study found that glucose-insulin-potassium (GIK) infusion therapy after a heart attack increased the risk of heart failure and death in the first 3 days. The therapy had no effect on 30-day or 6-month outcomes.
NIST nanowires have high Q factors, indicating stable vibrations, making them suitable as oscillators in nano-electromechanical systems. The wires' flat surfaces and material properties reduce noise and increase heat capacity.
Primary care physicians should prioritize identifying dementia red flags over routine screenings for individuals without symptoms, according to a commentary published in JAMA. Dementia red flags include medication issues, multiple hospitalizations, and agitation, which can help identify high-risk patients who require diagnostic testing.
PET imaging enhances lung cancer staging by providing complementary information on biochemical processes, accurately differentiating between benign and malignant tumors as small as 1 centimeter. The study also found PET to be more effective for mediastinal staging in non-small cell lung cancer.
Scientists found that 61% of hospital samples tested positive for ESBL-producing bacteria, which can break down common antibiotics. The spread of these strains has significant economic and health consequences, including longer treatment times and increased costs.
Researchers at UC Davis identified a cellular pathway involving microRNA miR-125b that contributes to the progression of prostate cancer. The discovery provides a potential target for reducing cancer deaths among American men.
A Canadian study reveals tobacco marketers are targeting teens near high schools by marketing in retail shops, often located near schools with high smoking prevalence. The study found that these stores offered lower prices, more promotions, and fewer health warnings, creating an environment that promotes student smoking.
A study published in Journal of Consumer Research found that men are more likely to enjoy melodramatic films if they know it's fictional. High-empathy individuals tend to dislike fact-based stories, while those with low empathy can appreciate fiction.
Computer simulation predicts Voyager 2 will reach major milestone in space, crossing the 'termination shock' one more time in mid-2008. The spacecraft's expected crossing of the spherical shell marks a significant event in its journey into interstellar space.
A new method to convert low-value glycerol from biodiesel production into a hydrogen-rich gas offers a promising solution for the transportation sector. The process, developed by Dr. Valerie Dupont and her team at the University of Leeds, produces a high-value product in demand for fertilisers, food production, and chemical plants.
Researchers at NIST create a stable superfluid flow in an ultracold atomic gas using laser light and magnetic fields. This breakthrough may lead to precise navigation gyroscopes and deeper physics insights.
A recent study found that patients with severe periodontal disease incur higher overall health care expenses compared to those with no periodontal disease. Treating periodontal diseases early on using simple non-surgical techniques can help restore a healthy mouth and potentially lower total health care costs.
Cases of lymphogranuloma venereum have surged in the UK, primarily affecting men who have sex with men, with many also infected with HIV. Experts are urging caution on new diagnostic tests that require careful validation before widespread use.
The use of RFID devices in patients raises benefits such as improved patient safety and expediting access to medical records. However, risks include potential unintended consequences, including loss of privacy and accessibility issues, as well as misuse by law enforcement or other malicious actors.
A new program called COGENT, developed at the University of Alberta, has been shown to improve reading and other cognitive skills in grade three students. In a one-year study, 73% of participants made significant gains in reading ability.
A University of Georgia study published in the American Journal of Clinical Nutrition found that obesity may be bad for bone health in young women. The research used advanced three-dimensional bone scans on 115 women aged 18-19 and found that obese participants had weaker bones by 8-9% compared to those with normal body fat.