A study found that black patients living in poorer neighborhoods were less likely to be placed on transplant waiting lists than white patients. Community poverty was a significant factor, rather than distance from transplant centers.
Researchers at Baylor College of Medicine found that inheriting two genetic mutations for epilepsy can actually reduce seizure frequency and severity. This discovery could lead to new gene-directed therapies for treating epilepsy.
Edmund H. Sonnenblick, a renowned NY cardiologist, received the national Research Achievement Award posthumously from the American Heart Association. His groundbreaking work helped redefine the human heart as a self-renewing organ, significantly advancing understanding of cardiac muscle structure and function.
Researchers found that each year as people age, the time it takes for their heart muscles to squeeze and relax grows longer. The actual amount of blood pumped out by the heart fell by 8 milliliters per year. This decline occurred despite an increase in another standard measure of heart function.
Ralph L. Sacco, a Florida neurologist, received the American Heart Association's Chairman's Award for his leadership in creating Power To End Stroke, a nationwide educational campaign aimed at raising stroke awareness among African Americans. The program has reached every state in the continental US and made measurable progress in spre...
Researchers have developed two molecular analogues of curcumin that demonstrate enhanced tumor suppressive properties against colorectal cancer. These new compounds have shown improved bioavailability and potency compared to natural curcumin.
A team of researchers from Wake Forest University has discovered a previously undetected chemical process within the oxygen-carrying molecule hemoglobin that converts nitrite salt to the vasodilator nitric oxide. This reaction mechanism could have far-reaching implications for treating cardiovascular diseases.
Researchers at Wake Forest University Baptist Medical Center found that older adults' ability to engage multisensory attention remains intact with age. Despite previous research suggesting otherwise, the study showed that older adults can speed up and slow down their brain's processing of relevant information, similar to younger adults.
A North Carolina team of doctors and nurses has created a model to provide faster treatment for heart attack patients. The RACE project uses caregivers from 65 hospitals and emergency medical teams throughout the state to diagnose and treat heart attacks more quickly, with median times improving by 22%.
Researchers found that inositol and IP6 protected human skin cells from UVB radiation damage and increased the potency of radiation therapy against cancer cells. The antioxidants may also offer protection against accidents or incidents involving nuclear material, such as dirty bombs.
A study found that college students who consume alcohol mixed with energy drinks are twice as likely to be hurt, require medical attention, or ride with an intoxicated driver compared to those who don't. The researchers also discovered that these students are more likely to take advantage of others sexually.
Darwin Labarthe, a renowned epidemiologist and educator, has been recognized by the American Heart Association for 40 years of mentoring young physicians and research fellows. He directed the training of over 885 participants during the annual seminar's 33-year existence.
A statewide program in North Carolina significantly improved the rate of coronary reperfusion for heart attack patients, reducing median door-in to door-out times by up to 49 minutes. While clinical outcomes remained unchanged, the study demonstrates that coordination of care can improve quality of care.
A recent study found that expanded criteria non-beating-heart kidney transplants from ECD donors are not suitable for elderly patients with ESRD. The risk of graft loss and death was significantly higher in these patients compared to brain-dead SCD donors.
A comprehensive analysis of the genomic changes underlying lung cancer has uncovered a critical gene alteration not previously linked to any form of cancer. The study revealed over 50 genomic regions frequently gained or lost in lung adenocarcinoma, with one region pinpointing an important gene that controls lung cell growth.
A rare hereditary disorder, Li-Fraumeni syndrome, has been identified in an Asian female with early onset breast cancer. Genetic testing may help diagnose LFS in young women with a family history of the condition, which increases the risk of developing multiple primary tumors.
Researchers at the University of Manchester have identified a genetic variant on chromosome 6 associated with rheumatoid arthritis. The discovery may influence the behavior of a nearby gene, tumour necrosis factor associated protein (TNFAIP3), which is involved in inflammatory processes.
A small, implantable device supporting the heart works equally well for men and women, benefiting twice as many women awaiting transplants. The device helps patients with severe congestive heart failure, enabling them to leave hospitals and return to active life.
The study provides a comprehensive view of the altered genetic background of lung adenocarcinoma, revealing new insights into its biology. The identification of the NKX2-1 gene highlights the importance of understanding the molecular properties of tumors to develop effective cancer diagnosis and therapy strategies.
Shigetada Nakanishi's work has led to new tools and drug targets in neuroscience. His discoveries are bringing a full understanding of the human brain closer.
Marc Alan Pfeffer identified destructive structural changes in the diseased heart and led clinical trials showing ACE inhibitors can slow or reverse these changes. His work expanded knowledge of hypertension and heart attacks' impact on cardiac muscle tissue, paving the way for effective treatment approaches.
Kenneth E. Bernstein identified key components of blood pressure control and was awarded the American Heart Association's Basic Research Prize for his work. His discoveries have led to a major approach in treating hypertension, coronary artery disease, heart failure, and diabetic nephropathy.
A comprehensive genome analysis of lung cancer cells has identified more than 50 frequent genetic changes, with less than half involving known cancer genes. The study also uncovered a critical gene alteration not previously linked to any form of cancer, shedding light on the disease's biological basis.
Recent studies have linked widely used osteoporosis drugs and bowel prep solutions to kidney damage. Nephrologists must be aware of these emerging causes of kidney problems and take steps to prevent them.
Dr. Paul K. Whelton has been awarded the American Heart Association's Population Research Prize for his pioneering work in documenting the burden of cardiovascular diseases. His research has provided vital data on hypertension and its impact on populations worldwide.
Researchers found that routine mammograms for breast cancer screening in older women on dialysis are unlikely to outweigh the costs, given their reduced life expectancy. The study suggests that breast cancer screening may not provide significant benefits for this population.
Research comparing music conductors and non-musicians found that experienced conductors
Researchers found that PAD prevalence increased from 3.7% to 4.6% among asymptomatic adults aged 40-70 between 1999-2004. The study suggests a link between rising obesity, diabetes, hypertension, and smoking rates, emphasizing the importance of screening for PAD in asymptomatic patients.