Researchers at EPFL have developed a nanoparticle vaccine that delivers vaccines more effectively with fewer side effects, at a fraction of the cost. The technology targets dendritic cells to trigger a strong immune response, and has potential applications for diseases like hepatitis and malaria.
A human peptide called LL37, normally used as a natural antibiotic, can bind to the body's own DNA and trigger an immune response. This may drive autoimmunity in psoriasis and other autoimmune diseases.
Researchers discovered that specific genetic variants of an odor receptor determine how people perceive pleasant or unpleasant odors. The study focused on two sex steroid-derived chemicals and found that different genetic variations led to varying reactions.
A new study reveals that a single gene, OR7D4, plays a crucial role in determining how people perceive the scent of androstenone, a potent ingredient in male body odor. Variants of this gene can make humans perceive androstenone as sweet or unpleasant, with some unable to detect it at all.
A new study reveals that genetic variation in regions controlling gene activity is a significant contributor to common diseases. The researchers analyzed the activity of almost 14,000 genes and found over 1300 genes affected by DNA sequence changes in regulatory regions.
Researchers have found that the protein responsible for producing geosmin, a soil-scented compound, has two distinct halves that work together to create the organic compound. This discovery could help microbiologists develop strategies to block geosmin in drinking water, which can cause an unpleasant taste.
Researchers at the University of Pennsylvania have created a new form of computer memory using nanowires that can store data for 100,000 years and retrieve it up to 1,000 times faster than current technology. The device uses less power and space than existing memory technologies.
A recent study published in Nature Medicine found that a byproduct of cholesterol metabolism, 27-hydroxycholesterol (27HC), interferes with the protective effects of estrogen on the cardiovascular system. When 27HC levels are high relative to estrogen, it blocks estrogen's function and leads to a loss of protection against heart disease.
The Smithsonian is a key player in the Barcode of Life Initiative, which aims to revolutionize species identification using DNA barcoding. With over 280,000 records, this technique has practical applications for food safety, disease prevention, and environmental monitoring.