Researchers at Whitehead Institute have modeled the complete process of nucleus ejection in mature red blood cells, revealing key proteins involved. The discovery sheds light on an essential step in mammalian evolution and may lead to insights into genetic disorders.
Researchers have identified a new cellular receptor, integrin alpha 4 beta 7, that plays a crucial role in the early stages of HIV infection. The receptor, which guides immune cells to the gut, is targeted by the virus's gp120 protein, facilitating its entry into host cells.
Researchers found that rats given artificial sweetener saccharin consumed more calories, gained weight, and did not compensate later. The study suggests that breaking the connection between sweetness and high-calorie food can confuse the body's ability to regulate intake.
A team of researchers has identified a new mechanism that explains why some recurrent ovarian tumors become resistant to treatment with cisplatin and carboplatin. They found that secondary mutations on the BRCA2 gene restore DNA repair function, making cancer cells resistant to chemotherapy.