A genome-wide study has identified 18 DNA variants associated with blood lipid levels, including six new regions never before linked to cholesterol and triglycerides. These findings hold promise for predicting genetic risk of heart disease and identifying novel targets for cholesterol-lowering therapies.
SourceBroad Institute of MIT and Harvard·JournalNature Genetics·DateJan 13, 2008
A new study confirms a connection between decreased height and increased risk of osteoarthritis, suggesting that genetic variants may play a role in both conditions. The research analyzed the genomes of over 35,000 people and identified a variant associated with an average difference in height of about 0.4 centimeters.
SourceUniversity of Michigan·JournalNature Genetics·DateJan 13, 2008
Researchers used computer modeling to show Baryonyx's skull bent and stretched like a crocodile's while eating, revealing it was a fish-eater despite its dinosaur appearance. The discovery sheds light on the evolutionary history of this unusual creature.
SourceUniversity of Bristol·JournalJournal of Vertebrate Paleontology·DateJan 13, 2008
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A international study of 20,000 people identified seven new genes associated with good cholesterol (HDL) and triglycerides, while confirming the role of bad cholesterol (LDL) in heart disease. The findings suggest that genetic variants influencing HDL levels are not directly linked to lower risk of coronary artery disease.
SourceUniversity of Michigan·JournalNature Genetics·DateJan 13, 2008
Research from the University of Bristol finds Antarctic ice loss is concentrated at narrow glacier outlets, driven by accelerating ice flow, and may dominate the ice sheet mass budget. The study estimates a total loss of 192 billion tonnes of ice over the past decade.
SourceUniversity of Bristol·JournalNature Geoscience·DateJan 13, 2008
A new study found evidence that common genetic variants linked to osteoarthritis may also play a minor role in human height. The variants, associated with an average difference of about 0.4 cm, lie in the region of the GDF5 gene, which influences cartilage development and bone growth.
SourceNIH/National Human Genome Research Institute·JournalNature Genetics·DateJan 13, 2008
Scientists at the University of Minnesota Center for Cardiovascular Repair successfully grew a functioning beating heart by reseeding dead rat and pig hearts with live cells. The decellularization process shows promise for creating transplantable blood vessels or whole organs made from a patient's own cells.
SourceUniversity of Minnesota·JournalNature Medicine·DateJan 13, 2008
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Researchers discover that individual brains are adapted to their unique auditory environment and can learn to localize sounds. The study may lead to more sophisticated hearing aids and speech recognition systems.
SourceBiotechnology and Biological Sciences Research Council·DateJan 13, 2008
Researchers have discovered more than 25 genetic variants associated with lipid levels, including seven previously unknown genes. These variants may lead to new strategies for treating and preventing coronary artery disease.
SourceNIH/National Institute on Aging·JournalNature Genetics·DateJan 13, 2008