A new study published in Nature Medicine reveals why tPA, the most effective emergency stroke treatment, carries risks of brain bleeding. Researchers found that the leukemia drug Gleevec inhibits a protein receptor involved in this effect, suggesting it could prevent problems and improve treatment outcomes.
A new group of stem cells in the epicardium can regenerate cardiomyocytes, smooth muscle cells, endothelial cells, and fibroblasts. This finding advances the hope of recapitulating developmental events to regenerate injured heart tissue, with potential applications for treating adults with heart failure.
Researchers have identified natural gold nanoparticles in Western Australia's groundwater, providing new insights into geological processes and potential gold deposits. The discovery could aid explorers in finding new gold deposits due to the unique properties of these nanoparticles.
A study published in Nature Medicine reveals that combining tPA with the leukemia drug imatinib reduces the risk of brain bleeding in mice, even when given late after stroke onset. This finding has great promise for increasing the effectiveness of tPA treatment in stroke patients.
A DNA study has identified genetic locations that contribute to differences in body shape, weight, fur color, and behavior among various dog breeds. This breakthrough may lead to better care regimes and tailored products for pet health.
Researchers discovered how filopodia extensions are generated and integrated with lamellipodia/ruffles in human cancer cells. The study reveals a complex interplay between these actin-based structures, suggesting that suppression of filopodia is needed for efficient cell migration.
Researchers at UCLA discovered that rapamycin reverses learning deficits caused by tuberous sclerosis complex (TSC), a genetic disorder also linked to autism. The study shows that the disease's impact can be reversed through biochemical changes, restoring normal brain function and memory.
Researchers have found that the special atomic structures formed in glass when it cools are responsible for its non-crystalline state. This breakthrough could lead to the development of new materials like metallic glasses, which could be used in flexible products such as aircraft wings and engine parts.