Researchers discovered a drug combination that inhibits glycolysis and intensifies cellular starvation, resulting in over 90% cell death in human tissue cultures of acute lymphocytic leukemia. The novel approach offers a promising alternative to current treatments.
The American College of Physicians (ACP) is urging comprehensive reforms to address the declining state of primary care medicine in the US. The ACP suggests that payment policies need to be restructured to prioritize patient-centered medical home models, which focus on continuous and coordinated care.
Researchers at NIST have confirmed that underground tunnels can have a frequency 'sweet spot' where signals travel several times farther than at other frequencies. The optimal frequency depends on tunnel dimensions, with a typical subway-sized tunnel finding its sweet spot in the 400 MHz to 1 GHz range.
Researchers at WashU Medicine found that a bone-strengthening drug called zoledronic acid reduced the growth of breast tumor cells in bones by 23% after three months. Women treated with the drug were also less likely to develop large metastatic tumors, suggesting it may help prevent cancer spread.
A team of scientists found that intrinsic disorder in relaxor crystals leads to their extreme sensitivity to mechanical pressure or voltage. This property makes them useful for applications such as medical ultrasound imaging, loudspeakers, sonar, and computer hard drives. The research was published in Nature Materials.
A Phase II clinical trial led by researchers at The University of Texas M. D. Anderson Cancer Center found that Iressa enhanced the effectiveness of hormonal therapy in treating specific types of metastatic breast cancer. The combination resulted in a 45% reduction in risk and improved clinical benefits for patients.
Researchers at NIST developed a new method to sort carbon nanotubes by length using high-speed centrifuges. This technique shows promise for scaling up production of high-quality nanotubes with specific lengths, crucial for various applications in electronics, medicine, and displays.
Researchers develop a biomarker to detect pleural mesothelioma through plasma osteopontin levels. NYU Cancer Institute also explores using microRNAs to discover novel biomarkers and presents a new strategy for restoring androgen sensitivity in prostate cancer, as well as a potential melanoma vaccine
A new biosensor measures the oxidation state of glutathione, an important protection molecule, to detect cellular stress. The sensor is highly sensitive and precise, allowing researchers to track short-term variations in oxidative processes.
A new study found that submucosal fibroids may migrate to the endometrial cavity after uterine artery embolization (UAE), but most are expelled spontaneously. Women can choose alternative treatments like hysteroscopic resection and/or myomectomy for better management of symptoms.
Researchers identified proteins that may serve as reliable biomarkers for Neurofibromatosis 1 (NF1) and its associated malignant tumors. Adrenomedullin levels were found to be significantly higher in NF1 patients and MPNST cell cultures, indicating a possible association with tumor growth.
Researchers Dekel, Jackson, and Wolinsky analyze the economics of election year promises, finding that direct vote buying involves lower costs, while campaign promises lead to higher payments for voters. The study provides insight into election strategy and its economic implications.
Researchers at WashU Medicine found that disabling an enzyme that attaches sugars to a hormone increased fertility levels in mice by nearly 50 percent. The altered hormone regulation may be used to enhance human fertility.
A new study from the University of Rochester Medical Center warns that temporary separations from one or both parents before kindergarten can predict disadvantages in the classroom. Children who experience separation scored significantly worse on measures of learning and pre-literacy skills, but fared better on expressive language and ...
A new study has found that antimicrobial ingredients in personal care products, such as triclosan and triclocarban, persist in estuarine sediments and can harm aquatic life. The study also discovered a potential pathway for the breakdown of these chemicals, but notes that their continued use poses significant environmental risks.
CAPHOSOL, an advanced electrolyte solution, has been shown to relieve oral mucositis and improve quality of life for cancer patients. The study found that 95% of patients reported favorable OM scores and high levels of patient and practitioner satisfaction with CAPHOSOL.
The milk-derived dietary supplement AmealPeptide has been shown to significantly reduce daytime ambulatory systolic blood pressure by 3.6 mmHg and 24-hr systolic blood pressure by 6.2 mmHg in two placebo-controlled trials, confirming its safety and efficacy for patients with Stage I and Stage II hypertension.
A new study suggests that the depth of cancer penetration in the bowel wall affects survival rates, and proposes changes to current guidelines. Patients with thin lesions confined to the bowel wall have better survival outcomes than those with thicker cancers.
Scientists at the University of the Basque Country have developed robots with improved precision control using shape-memory alloys. These materials enable precise positioning, making them suitable for applications such as machine tooling and large-dimension telescopes.
Scientists at The Wistar Institute have developed a novel enzyme inhibitor that effectively blocks a key biochemical pathway in cancer development. By targeting the PI3K enzyme, the agent shows promise in treating melanoma by dampening overactive enzyme activity that leads to uncontrolled tumor growth.
Researchers discovered extensive deep-sea coral habitats off the coast of North Carolina, containing commercially valuable fish populations and many newly discovered species. The reefs are important habitats for several species and contain historical data about changing ocean climate and productivity.
A Phase III clinical trial found that everolimus significantly delays cancer progression in patients with metastatic kidney cancer. The study showed a 26% reduction in disease progression after six months compared to the placebo group.
A team of international scientists mapped and analyzed geologically young faults in Sichuan Province, finding clear evidence of slip during the last few thousands of years. The faults showed rates of slip varying between fractions of mm per year to possibly many mm per year.
The National Institute of Standards and Technology (NIST) has developed Standard Reference Materials (SRMs) for bitter orange, a compound used in herbal weight-loss products. Researchers can use these materials to develop and test analytical methods, as well as ensure the quality of their measurements.
Researchers at NIST have developed a new class of materials that can store relatively large quantities of hydrogen for later release. The material combines lithium amide with lightweight metal hydrides, resulting in improved hydrogen storage properties.
Researchers have developed a novel method to expand natural killer cells from umbilical cord blood, effectively killing human leukemia cells in mice. The treatment demonstrates significant cytotoxic activity against both acute lymphocytic leukemia (ALL) and acute myelogenous leukemia (AML).
Dr. Kristina M. Johnson, an IEEE Fellow and electrical engineer, received the John Fritz Medal for her internationally acknowledged expertise in optics and optoelectronic switching technology. She was also recognized for increasing women engineering faculty at Duke University.