ESnet4 network provides highly reliable, high-bandwidth connectivity to support and advance the US scientific community. The award recognizes ESnet's efforts to meet the increasingly data-intensive demands of the DOE research community.
A new study analyzes interactions on the Moon among electrostatic adhesive forces, sun's rays angle and lunar gravity to conclude stickiness changes with sun elevation. Forces compelling dust to cling to surfaces weaken as sun moves higher in sky, allowing lunar gravity to pull off.
The Elluam Tungiinun project, rooted in a Pulitzer Prize-winning series, has found that culturally appropriate ways can help Alaska Native youths find reasons to live and avoid substance abuse problems. The program uses cultural activities such as fishing and berry picking to teach protective factors that promote wellness.
Researchers have developed antedrugs that effectively reduce inflammation without causing damage, surpassing the potency of conventional steroids. The new compounds, isoxazoline derivatives, were five times more potent in binding affinities to cell receptors and reducing inflammation.
TGen researchers have identified a potential therapeutic target for glioblastoma multiforme (GBM) by regulating the actions of NHERF-1, a gene implicated in tumor cell migration and division. Depletion of NHERF-1 stops GBM cell migration, suggesting its role in tumor invasion.
Researchers at Johns Hopkins Medicine tracked how prostate cancer began in 33 men, finding a set of genetic defects in a single cell that differ for each person's cancer. The study suggests that common genetic patterns across metastatic sites indicate a single cell source.
The University of Pittsburgh has received a five-year, $2.8 million grant to develop training sites in Mozambique, Brazil, and India for HIV/AIDS researchers. The program aims to equip local researchers with skills to monitor patients and combat drug resistance.
Researchers have identified a genetic mechanism in bacteria that could lead to the development of new antibiotics. The preQ1 riboswitch regulates gene expression by controlling the availability of queuosine, a molecule essential for bacterial survival and human disease.
A team of scientists studied how alligators grow and develop in different oxygen levels, discovering that low oxygen environments result in enlarged bellies and smaller organs, but also larger hearts. The study provides insights into the adaptations of dinosaurs to survive in a world with fluctuating oxygen levels.
Exposure to secondhand tobacco smoke, wood smoke, or cooking oil smoke for as little as 10 minutes affects cardiovascular function in both men and women. Men exhibit a stronger sympathetic response, while women show a healthier parasympathetic response. These findings confirm previous research on the negative effects of tobacco smoke o...
Researchers found that maternal exercise was associated with increased fetal breathing movements and improved fetal heart rate variability. Fetal breathing movements are a marker of fetal well-being and reflect functional development of the respiratory system and central nervous system control.
Researchers created a computational model to examine the role of certain proteins in familial Alzheimer's disease. The model found no link between amyloid beta plaques and tau tangles, but suggested that genetic mutations in proteins and GSK3 over-activation may contribute to the development of the disease.
Researchers found that phosphodiesterase type 5 inhibitors, commonly used to treat male erectile dysfunction, can also relax female rat internal pudendal arteries and improve blood flow. The study suggests that these drugs may be effective in treating female sexual dysfunction caused by inadequate blood supply.
A Scripps Research Institute team has successfully synthesized kapakahines, marine-derived natural products with anti-leukemia potential, in large quantities for the first time. The breakthrough allows research on the compound to proceed, potentially leading to new drug treatments.
A recent study published in Science found that Ichthyostega, a four-limbed animal with backbones, may have been the more primitive form, acquired terrestrial habits later in development. In contrast, Acanthostega's limbs showed more similarities to earlier fish fins, indicating it may have returned to an aquatic lifestyle.
A new study found that oral contraceptive use impairs muscle gains in young women, with lower hormone levels and elevated cortisol concentrations. The researchers also noted significant differences in lean mass gains between OC users and non-users.
New studies suggest male impotence drugs like Viagra, Levitra, and Cialis may also treat female sexual dysfunction. Researchers found the drugs relax blood vessels in females differently than males, with some women more sensitive to certain medications.
A new study examines the impact of social isolation on rats' response to cocaine, revealing that isolated male rats are more susceptible to the drug's effects. The research suggests that early isolation can alter brain sensitivity to cocaine, leading to increased sensitivity in adolescence.
Patients in the active treatment group experienced significant improvements in nasal symptoms, sense of smell, and a reduction in nasal swelling. The study showed a highly significant improvement to a normal state in the nasal mucosa, with peak nasal inspiratory flow and rhinosinusitis outcome measures also significantly improved.
Researchers at UT Southwestern Medical Center found that PCSK9, a protein responsible for regulating 'bad' cholesterol, works almost exclusively outside cells. This discovery provides opportunities to develop therapies to block the protein's disruptive actions and reduce plasma cholesterol levels.
The article examines how the Columbine High School shootings were originally portrayed in the media and how those messages changed after 9/11. The author argues that framing the event as 'terrorism' contributed to a broader discourse of fear, legitimating the war on terror and expanding social control.
Researchers found that mirthful laughter reduced stress hormones and increased HDL cholesterol in diabetic patients, lowering the risk of cardiovascular disease. The study suggests that adding laughter therapy to standard care may improve health outcomes.
A new study found that coffee and caffeine supplementation reduced oxidative stress and cell death in male mice with ALS, while female mice showed no benefit or even increased markers of stress. The researchers suggest women may want to restrict or switch to decaf products with antioxidants.
Researchers at NC State University have found an exponentially better way to protect streams and lakes from the muddy runoff associated with stormwater around road and other construction projects. The alternative method uses natural fiber check dams enhanced with polyacrylamide, significantly reducing sediment loss and pollution.
Calculations suggest low-oxygen dead zones in the ocean will expand significantly over the next century. Marine animals will need more oxygen to survive as carbon dioxide levels increase, exacerbating the effects of 'dead zones'.
A study found that even low levels of lead in children's blood can increase vascular resistance and decrease aldosterone levels, which may predispose them to hypertension. The researchers also discovered increased sympathetic nervous system activity during rest and a paradoxical depression of this response during stressful tasks.
Microbes adapted to manipulate sulfur and iron compounds to survive in the absence of photosynthesis. The discovery provides insights into the origins of life on Earth and offers a unique laboratory for studying life in hostile environments.
The US Navy has successfully demonstrated a revolutionary new counter-mine technology for ships, utilizing superconducting ceramic materials to neutralize the magnetic signature of the ship. This technology provides a warfighting advantage and can act like a cloaking device to eliminate the magnetic signature of the ship.
The Office of Naval Research (ONR) has developed a fuel cell powered UAV that can travel farther and carry heavier payloads than earlier battery-powered designs. This technology has the potential to significantly improve energy efficiency and reduce noise levels, making it ideal for military surveillance missions.
The Office of Naval Research has awarded 15 young researchers with three-year research grants worth up to $510,000. The winners were selected from 193 proposals and include faculty members at top universities, such as Harvard College and Cornell University.
Research reveals that exercising during pregnancy does not require sacrificing time for other activities. Exercisers actually spent slightly more sleep and reading time, while non-exercisers spent more on TV/computer time. The study also found significant differences in BMI and maternal weight between exercisers and non-exercisers.
A low-dose of naltrexone reduced symptoms of pain and fatigue by an average of 30% in women with fibromyalgia, according to a Stanford pilot study. The drug's use was found to be particularly promising due to its low cost and limited side effects.
A new study finds a significant decline in the number of entering college freshmen needing remedial English and math classes since 2004, with a 6-percentage point drop in Sacramento State's population. This reduction equals about 2,000 fewer students in remedial math and 3,000 in remedial English courses across the CSU system.
Researchers at Johns Hopkins Children's Center found that prenatal exposure to maternal antibodies can trigger neurobehavioral changes similar to autism in mouse pups, including increased anxiety and hyperactivity. The study suggests that the immune system may play a key role in some cases of autism.
Researchers used mouse models to study Huntington Disease, finding significant protein alterations as early as 2 weeks before symptoms appear. These changes may affect late-stage disease by altering biochemical activity in the brain.
Research by the University of Massachusetts Medical School found a 20.8% reduction in daily smoking among 10th graders after enforcement of the Synar Amendment. This law makes it financially dangerous for shops to sell tobacco to underage customers, reducing cigarette supply to vulnerable groups.
Astronomers have identified a triple merger of four separate galaxy clusters, the first time such a phenomenon has been documented. The galaxy clusters are involved in a cosmic free-for-all, with one collision after another occurring as galaxies pour into a region already full of galaxies.
A new nucleotide, 5-hydroxymethylcytosine, has been discovered in the mouse brain, opening a new front in epigenetic research. This discovery may challenge existing approaches to investigating DNA methylation and could have significant implications for understanding gene regulation.
University of Washington researchers found a combination of nanoparticles and chlorotoxin, a scorpion venom compound, cuts brain cancer cell spread by 98% compared to 45% with chlorotoxin alone. The additive treatment disables machinery that allows tumor cells to change shape, preventing further invasion.
Research using museum specimens found support for alternative hypotheses on the evolution of locally distributed endemism, suggesting multiple processes develop local endemism. This knowledge can help identify priorities in conservation planning.
Researchers use tightly focused blue and ultraviolet light to create patterned lithography on a substrate, resulting in smaller structures. The new technique has potential applications in constructing nanomotors and may lead to advancements in Moore's Law.
A University of Leicester team is developing a combined diagnosis/therapeutic strategy for prostate cancer using cutting-edge magnetic nanoparticles. The technology aims to identify and treat cancer cells at an early stage, reducing the need for surgical removal.
A new study reveals that droughts in West Africa can last for decades, with some droughts lasting up to four times longer than the current Sahel drought. The research suggests that changes in Atlantic Ocean sea surface temperatures play a key role in sustaining these long periods of drought.
A University of Colorado at Boulder study found that an in-class writing assignment increased the grade-point averages of African-American middle school students over a two-year period. The intervention reduced the rate at which these students were held back or placed in remediation, suggesting targeted psychological interventions coul...
A single protein called SopB allows Salmonella to invade cells and hijack cellular functions, enabling it to avoid destruction. The study reveals how SopB coaxes cells to mark the protein with ubiquitin, making it recognizable to cellular machinery.
Researchers at Emory University discover a process required for epigenetic reprogramming between generations, shedding light on fertilization, stem-cell formation, and cloning. The study found that histone protein modification can be inherited through cell-to-cell transmission.
Researchers at the Institute of Bioengineering and Nanotechnology have synthesized gold nanoclusters that can be used for sub-cellular biolabeling and bioimaging. These clusters are suitable for use within the body due to their lack of toxic metals, enabling scientists to monitor cell nucleus dynamics and study genomic changes.
Researchers at JILA have successfully controlled collisions between fermions, allowing for a significant boost in atomic clock accuracy. By understanding the dynamic effect of measurement processes, they reduced uncertainties in clock operation, making it 50% more accurate than previous results.
A study by Queen's University researchers found that pelvic pain symptoms occur as frequently in adolescent boys as in adult men. Chronic pelvic pain syndrome has a significant negative impact on quality of life, including depression and social relationships.
Researchers found that thermosensory neurons in C. elegans help regulate response to increasing heat by changing steroid signaling pathways, which affect longevity. This system allows worms to reduce the effect of warm temperature on aging processes, similar to how warm-blooded animals control their body temperature.
A North Carolina State University researcher has developed a method to deflect asteroids by attaching a long tether and ballast to the incoming object, changing its center of mass and orbit. This system shows promise in altering the motion of an asteroid to miss hitting Earth.
Researchers are implementing a wireless monitoring system for analyzing the safety of older bridges, utilizing wind and structural vibrations as its sources of power. The project aims to provide real-time data on bridge health, enabling proactive repairs and extending bridge lifespan.
Kansas State University is using a Second Life island called TerraWorld to help high school students learn geology through interactive simulations. Students can explore different time periods, complete quests and scavenger hunts, and interact with virtual role models.
Scientists have identified the two neural centers responsible for regulating sleep patterns, revealing that disruptions to these centers can cause jet lag. The study found that deep sleep is more closely tied to light-dark cycles, while REM sleep follows a separate internal clock, leading to a delay in adaptation to new schedules.
Researchers at Heidelberg University Hospital have shown that certain immune cells in the blood inhibit inflammation after a stroke. Regulatory T lymphocytes (Treg) play a key role in this protection and may offer a new approach to stroke therapy.
Researchers found that countries with high levels of ethnic exclusion are more likely to experience civil war. The study, led by UCLA professors Andreas Wimmer and Lars-Erik Cederman, analyzed data on ethnic power relations in 155 countries from 1946 to 2005.
Researchers have developed an almost year-by-year record of the last 3,000 years of West Africa's climate, revealing that catastrophic droughts occurred every 30 to 65 years. The new research suggests that global warming may exacerbate the normal climate pattern, producing even more severe and prolonged droughts.
Researchers found a key role for disrupted copper regulation in prion disease progression, suggesting that the loss of copper binding ability contributes to neurodegeneration. The study identified a threshold at four extra octarepeats, beyond which changes in molecular properties lead to toxic effects.
A study of 1970 patients found a strong association between gastroesophageal reflux disease and linked angina. Patients with GERD had a higher prevalence of linked angina than those without GERD symptoms, suggesting that GERD may be misclassified as non-GERD heartburn.
Scientists at IBN have successfully converted carbon dioxide into methanol using organocatalysts, a novel approach that offers a low-energy and non-toxic process. This breakthrough has significant implications for the sequestration and conversion of greenhouse gases, providing a viable alternative energy option.