A new study reveals that trans fats interfere with the regulation of blood flow by hindering key enzymes and reducing prostacyclin production. This can lead to increased inflammation, high LDL cholesterol, and calcified arteries, ultimately contributing to atherosclerosis and heart disease.
A new study suggests that common fish species, such as the nine-spined stickleback, can compare behavior and make choices based on personal experience, leading to better food supplies. This sophisticated social learning capability, called 'hill-climbing', challenges the idea that big brains are necessary for cumulative culture.
Researchers found that a novel therapy combining antibiotic-based hemoperfusion with conventional treatment significantly reduced mortality and improved blood circulation and organ function in patients with severe sepsis. The study's results suggest potential benefits for endotoxin-targeted therapy in septic shock.
Researchers found that individuating novel objects with unique names enhances holistic processing, a hallmark of face-like expertise. This technique can be learned quickly and applied to other objects, indicating that expert-level recognition is not solely the result of extensive practice.
A new combination therapy of daily consensus interferon and ribavirin has been found to be effective in some hepatitis C patients who have not responded to previous treatment. The study, led by a Saint Louis University researcher, showed a success rate of above 30 percent for patients with less severe liver damage.
Comparative effectiveness research can significantly improve health care quality and affordability if done correctly. Two key challenges are obtaining data earlier in the life cycle of new drugs and linking evidence to strategies that modify physician practice. The expert also highlights the need for a broader agenda, including lifesty...
A UCLA study reveals that depression may increase the risk of developing Alzheimer's disease in individuals with mild cognitive impairment. Researchers also found that the medication donepezil can delay the progression of Alzheimer's in depressed individuals with memory problems.
A study on rural tourists' profile in Spanish villages with limited inhabitants highlights the importance of emotional and cognitive aspects of travel. Key factors influencing traveler behavior include historical-cultural wealth, cleanliness, and welcome from local residents.
Researchers found that sinus infections are a primary cause of toxic shock syndrome in about one-fifth of cases in children. Children with both conditions had more severe symptoms and required intensive care, but prompt imaging studies can help diagnose the underlying infection.
Researchers have developed a novel form of treatment using an alpha-particle emitting radiopeptide that targets and destroys cancer cells while sparing healthy tissue. The study found that this therapy was significantly more effective at tripling the survival rate of mice with recurrent prostate cancer compared to traditional treatments.
Researchers have developed a low-cost strategy to discover new drugs for neglected diseases, utilizing global educational resources and distributed problem-solving. Students worldwide are synthesizing candidate molecules, meeting industry standards, and participating in the process.
A study found that psoriasis is associated with an increased risk of cardiovascular disease, including ischemic heart disease, cerebrovascular disease, and peripheral artery disease. Patients with psoriasis were also more likely to die from these conditions, highlighting the need for vigilance in screening for cardiovascular risk factors.
The University of Leicester has launched G-STEP, a business-facing service that harnesses space technology for earth-bound benefits. Researchers are working with businesses and public sector organisations to provide value-added services exploiting environmental data from the GMES system.
Researchers have developed a new crosslinking method called TRAP to study protein interactions in living cells. The method uses small crosslinkers that can be controlled with light to identify proteins working together, revealing new details about RNA polymerase in bacteria.
Researchers at Northwestern University have developed a novel method to separate cancer cells from normal cells by directing their movement along preferred directions. The technique utilizes ratcheting technology and has the potential to create a
Researchers found that microglial cell degeneration contributes to loss of neurons and dementia, contradicting the popular neuro-inflammation theory. The study suggests that anti-inflammatory drugs may not be effective in fighting dementia.
A new study identifies New York and eastern U.S. cities as prime locations for exploiting high-altitude winds, which contain enough energy to meet world demand 100 times over. The regions match population centers and have high wind power densities, but fluctuating wind strength poses a challenge for large-scale exploitation.
A study published by Cincinnati Children's Hospital Medical Center identified a critical gene, SHP2, essential for normal heart and skull formation. Neural crest cells' differentiation failure leads to severe anatomical and functional deficits.
Researchers at King's College London discovered a key element in the development of chronic asthma, linking airway remodelling to muscle cell changes. The study found that reducing SERCA2 levels in airway muscle cells may lead to effective new treatments for severe asthma.
Researchers have discovered that calcium modulation affects long-term memory specifically while leaving learning and short-term memory intact. The study found that increased calcium levels during learning led to stronger responses to olfactory stimuli associated with food, indicating improved memory performance.
Temple University's School of Podiatric Medicine has received a $650,000 NIH grant to test the effectiveness of a personalized, visual diabetic foot education strategy. The program aims to improve health literacy and empower patients to make better decisions about their foot care.
High levels of brain energy are necessary for maintaining consciousness, according to Yale researchers. The study proposes that a conscious person requires a high level of brain energy, which supports human behavior and should be considered when interpreting fMRI signals.
Researchers at MIT identified the cause of concrete creep and found a way to slow its rate, enabling ultra-high-density materials that can last hundreds of years. This breakthrough could lead to enormous cost-savings and reduced CO2 emissions in construction.
A new study by researchers at Rush University Medical Center found that possessing a greater purpose in life is associated with lower mortality rates among older adults. The study used data from 1,238 community-dwelling elderly participants and found a substantially reduced risk of mortality among those with high purpose in life.
The Palomar Transient Factory (PTF) utilizes NERSC's tools to uncover relatively rare cosmic events like supernovae and gamma ray bursts, discovering over 40 in its commissioning phase. The survey combines automated analysis with high-end systems and networks, enabling rapid follow-up observations.
A recent MSU-led study found that Brazil's protected areas within the Amazon can buffer the forest from climate change even if the remaining area is deforested. The researchers used atmospheric computer modeling to simulate a worst-case scenario and found rainfall levels would not decrease significantly.
Scientists have identified a new approach to detect and treat Peutz-Jeghers syndrome, a rare inherited cancer syndrome, by exploiting tumors' weak spot in glucose metabolism. They found that targeting mTOR pathway with rapamycin can stop tumor growth, offering new treatment options.
Researchers have gained insight into the regulation of aquaporins in yeast cells, revealing a previously mysterious region that acts as a gate controlling water flow. This discovery may lead to the development of inhibitors for human aquaporins, which could slow down cancer tumor growth.
Scientists from A*STAR's IMRE invented the world's smallest controllable molecule gear of 1.2nm size, revolutionizing molecular machines. The breakthrough was achieved through optimizing molecular design, manipulation and surface atomic chemistry.
The USF-Moffitt Cancer Center has been awarded a $6 million grant to create a National Center on Minority Health and Health Disparities Center of Excellence. The center will focus on reducing health disparities among minority and underserved communities in Florida through research, education, and community outreach.
Scientists have identified a method to predict which HIV-positive individuals are most susceptible to deadly fungal meningitis. The study found that people with low levels of IgM memory B cells are more likely to develop the disease, suggesting a genetic predisposition.
A study by Indiana University Center for Health Policy and Professionalism found that 59% of physicians support government legislation for National Health Insurance. Nearly every medical specialty showed an increase in levels of support for national health insurance.
Researchers at Virginia Commonwealth University discovered a stable cluster of atoms that can mimic different elements of the periodic table, exhibiting strong magnetic properties. The discovery has potential applications in creating faster computers, larger memory storage, and molecular electronic devices.
A new study found that consumers experience greater delight when winning a prize without immediate knowledge of its value. This positive uncertainty can stimulate mental imagery and prolong positive feelings, making winners more receptive to marketing messages.
A study by UC Davis geochemists has produced the first picture of how different isotopes of iron were initially distributed in the solid Earth 4.5 billion years ago. The discovery could lead to investigations into the evolution of Earth's mantle and its geologic history.
Researchers successfully treated basal cell carcinoma with a non-toxic radioactive patch, showing minimal scarring and no toxicity. The treatment delivered beta radiation to the cancer site, effectively eradicating the malignant cells.
Researchers found that thinking about similar experiences accelerates recovery from satiation, as people tend to forget the variety they had in their lives. By recalling past favorite experiences, consumers can regain enjoyment and appreciate their current experience more.
Research by Sievert Rohwer and colleagues reveals that maximum body size in birds is constrained by the molt process. As bird size increases, feathers wear out before they can be replaced, requiring alternative strategies to maintain aerodynamic support. This fundamental relationship ultimately limits the size of flying birds.
Researchers at the University of Leeds have discovered a key mechanism governing gene evolution, revealing that protein REST controls gene expression by binding to specific genetic sequences. This process has been shown to play a leading role in the evolution of intelligence in mammals, particularly in the brain.
Researchers at the University of California, Berkeley, have found a critical piece in the puzzle about how stress causes sexual dysfunction and infertility. Stress hormones, such as glucocorticoids like cortisol, inhibit the body's main sex hormone GnRH, while also increasing another hormone GnIH, which directly inhibits GnRH.
Research by Sabrina McCormick links everyday products to breast cancer, citing industrial pollution and agricultural pesticides as contributing factors. Experts urge policymakers to ban cancer-causing chemicals in everyday products, promoting prevention over a cure.
Researchers investigated calcium supplementation's effect on obese patients' weight loss, found no benefits. Red yeast rice capsules improved LDL cholesterol levels in statin-intolerant patients without muscle pain side effects. Colonoscopy-related adverse events were low but increased with age and specific comorbid conditions.
Researchers found that brief motivational interviews and one-on-one counseling programs significantly reduced heavy drinking and improved behavior among high-risk students. Community-based initiatives, such as increased police patrols and online alcohol policies, also showed promise in reducing off-campus incidents involving students.
Researchers at Carnegie Mellon University have identified a novel regulatory gene network that plays a crucial role in the spread of invasive yeast infections. The study reveals that Zap1 protein regulates the production of biofilm matrix, promoting infection and drug resistance.
A new study in CMAJ reports that oseltamivir and zanamivir are relatively safe for use in pregnant and breast-feeding women during the H1N1 pandemic. Pregnant women, especially those in the third trimester, are at high risk of serious complications from the flu virus.
Researchers at Caltech discovered a material that does not expand when heated, like most metals, and behaves like a metal with an entirely different chemical composition. By applying high pressure, they created nonexpanding metal alloys by forcing electrons into new states.
Researchers at SNM's Annual Meeting discovered that combining motion-frozen technology and high-definition PET enhances cardiac imaging, revealing defects invisible to physicians. The method provides exceptional image quality and significantly changes the diagnosis of patients with heart disease.
The Carnegie Institution's CASE and Math for America (MfA) partnership aims to recruit, train, and retain effective secondary school mathematics teachers in Washington, D.C. The program has received a $1.5-million NSF grant to support 14 Fellows over the next four years.
A study on rats reveals that neural replay of past experiences occurs both during and after wakefulness, forming long-term memories more accurately. The hippocampus replays events in peppered bursts, often involving different settings, suggesting elements of past experience are constantly reactivated.
Research finds stalled microtubules in cells with faulty dynamin 2 protein, leading to reduced nerve impulse strength and slowed movement. The stable microtubules disrupt normal cellular processes, including the formation of the Golgi complex.
A new tool developed at Purdue University helps sort out how to choose the best non-point source pollution control strategies for water resources. By analyzing data from an area, it can compute the most cost-effective solutions in just a few hours.
Researchers found that applying a chemotherapy medication to the face reduced actinic keratoses by 87% and improved signs of aging. The treatment also showed promise in addressing photo-aging, with patients reporting improved skin appearance and willingness to undergo therapy again.
Researchers have developed a new fully integrated PET/MRI system that can provide whole-body images of rats and small animals. The system offers significant improvements in imaging capabilities, enabling increased understanding of disease characteristics and physiological processes.
Researchers found that young autoreactive T-cells are more receptive to reeducation into regulatory T-cells. In contrast, older T-cells become fully activated and cause damage. Understanding the developmental stage of T-cells holds promise for developing new therapies for autoimmune diseases.
Researchers found that people are more likely to buy Extended Service Contracts for hedonic products like game controllers, which hold value due to the pain of potential loss. Price promotions also play a role, with low-income consumers more likely to purchase ESCs as they cannot afford replacements.
The new issue of Reproductive Health Matters highlights the need for comprehensive efforts to strengthen public health systems and create a well-trained workforce. Mid-level providers are willing to take on increased workloads, raising questions about quality of care and financial remuneration.
Researchers at the University of Alberta have discovered how proteins recognize and repair damaged DNA. The proteins bend the DNA double helix to amplify damage recognition, enabling the next protein to cut out the damaged section. This process can be used to develop new cancer treatments and disease prevention strategies.
A team of researchers led by Dr. Jayakrishna Ambati at the University of Kentucky has discovered a biological marker for neovascular age-related macular degeneration (AMD). The marker, CCR3, shows strong potential as a means for both early detection and preventive treatment.
A study in Journal of Consumer Research found that India's anti-Coca-Cola movement employs nationalism and swadeshi ideology, invoking imagery of foreign invasion and exploitation. The authors argue that global brands can become symbols of oppression, with implications for multinational corporations and policy makers.
Researchers at Whitehead Institute for Biomedical Research discovered a microRNA, miR-31, that inversely correlates with metastasis in breast cancer. Increasing miR-31 levels can help predict patient prognoses and potentially aid in the development of targeted therapies.