A new study from the University of Michigan Comprehensive Cancer Center found that a single round of chemotherapy can identify patients most likely to benefit from preserving their speech. After three years, 78% of T4 study participants were still alive and 58% had an intact larynx.
Year 10 students from Hadden Park High School in Nottingham are using advanced GPS technology to map fragments of heathland at Sherwood Pines Forest Park. The project aims to raise awareness of heathland and develop habitat corridors to protect species affected by climate change.
A recent study published in Science found that the STAT3 protein plays a key role in converting normal cells to cancerous cells by regulating gene expression in both the cell nucleus and mitochondria. This discovery may lead to the development of targeted cancer therapies.
The Veritide Ceeker portable bacterial detection device has been shown to accurately identify anthrax spores and distinguish them from hoax substances. With results produced in minutes, the device enables first responders to rapidly determine whether a situation is a nuisance or a major threat to public health.
Researchers found that amitriptyline can directly stimulate molecules that help neurons grow and resist toxins, suggesting a separate mechanism for its antidepressant effects. The study suggests that this property may be the key to understanding how some antidepressants work.
A global Framework Convention on Alcohol Control is seen as crucial to addressing the alcohol-related health crisis. Non-governmental organisations and governments must work together to overcome industry resistance and generate political priority for alcohol control efforts.
A T-STAR grant has funded genetic studies on Pacific white shrimp, papaya cultivars and endangered Cycas micronesica cycad. The research aims to improve disease tolerance and pollination processes, supporting aquaculture and conservation efforts.
Researchers at Vanderbilt University Medical Center used NMR methods to determine the structure of diacylglycerol kinase (DAGK), a large bacterial protein that resides within the cell membrane. The study suggests that similar methods can be applied to other membrane proteins, including G protein-coupled receptors, which are targets for...
A study on quality improvement (QI) research found that most studies had methodological limitations, including inadequate study duration, selection bias, and poor implementation. The review highlights the need for longer-term results and improved intervention design to accurately assess QI effectiveness.
Scientists found that adult muscle stem cells can regenerate muscles after injury without the two key embryonic muscle cell genes Pax3 and Pax7. This discovery challenges current research on muscular dystrophy and regenerative medicine, suggesting that age-matched stem cells may be more effective for therapy.
The researcher aims to understand how neurons store information and decide which memories to retain. UT San Antonio scientist Brian Derrick is studying the role of the dentate gyrus in preserving episodic memories using a $917,000 NIH grant.
The American Le Mans Series has introduced a green racing initiative, awarding prizes to the fastest cars producing the smallest environmental footprint. The concept aims to accelerate innovation in everyday life, reducing dependence on foreign oil.
Patients with ischemic stroke and moderate to severe OSA who received CPAP treatment had a significantly lower risk of death compared to those who did not comply. The study found that nearly half of the original group had died within five years, while only 28 were fully compliant with CPAP treatment.
Researchers have produced video footage of a male nematode worm preparing to mate with a hermaphrodite, showcasing the complex process. The study revealed that the male uses acetylcholine to regulate tail muscles for an exploratory embrace, and then searches for the vulva before mating commences.
The University of Leeds has been awarded $18 million in funding to improve the quality of life for older adults. The new Centre of Excellence in Medical Engineering will focus on developing innovative therapies to address age-related degeneration, with the goal of creating '50 more years after 50'.
Researchers uncover jawbone of transitional fossil Megapiranha paranensis, showing intermediate pattern of teeth. The discovery confirms the evolutionary link between piranhas and their herbivorous relatives, with implications for understanding the piranha's distinctive bite.
A study found that El Nino years favor the Australian team's success in the Ashes series held in Australia, while La Nina years benefit England. The research analyzed Ashes matches from 1882-2007 and showed a strong correlation between ENSO phases and team performance.
New research reveals that diabetes costs the US economy over $174 billion annually, with a focus on lifestyle modifications and preventive care. Implementing pay-for-performance incentives can significantly reduce these costs by encouraging improved disease management and adherence to clinical guidelines.
A UCSF study of nearly 2,000 middle-aged and elderly women reveals that physical problems are less likely to impact their sexual activity than their partner's health or interest. The study also shows significant racial differences in sexual desire, satisfaction, and activity.
Two NTU projects win up to S$4 million in research funds for fast and efficient detection of Cryptosporidium in water using genetic analysis and biophotonic chips. The technologies aim to enable prompt implementation of control measures, reducing time and manpower required.
Researchers discovered that prion proteins bind more stably to copper in human bodies, which may prevent their misfolding. The study suggests that copper binding could play a beneficial role in early stages of prion diseases such as Alzheimer's and Parkinson's.
A study by the USDA Forest Service and university scientists found that climate plays a critical role in shaping wildfire behavior, particularly in the Western United States. Climate influences fuel production and drying, which varies among different ecosystems, leading to varying fire sizes and severities.
The Lancet report reveals that 3.8% of global deaths are attributable to alcohol, with the majority being caused by injuries, cancer, cardiovascular disease, and liver cirrhosis. Men drink more than women, and the risk is higher in developing countries.
Cancer patients often suffer from severe pain due to tumors releasing signal substances that make nerve cells sensitive; a new approach involves injecting proteins that block these effects. This discovery opens up new prospects in the fight against cancer pain and potentially reduces side effects for patients.
A recent study found that contrast-induced kidney damage from medical imaging procedures increases the risk of having a stroke or heart attack over the next year or two. Patients who developed this damage had twice as many long-term negative health effects compared to those whose kidneys were not damaged.
Researchers at Gladstone Institutes have found a key factor controlling HIV latency, which could lead to new strategies for clearing the virus. The discovery involves DNA methylation and a host protein called MBD2, and offers hope for future therapies to reactivate latent HIV.
A study published in Investigative Ophthalmolgy & Visual Science found that multiple genetic, ocular, and environmental factors contribute to the incidence of AMD. Researchers developed a predictive model using these variables, which can be used to guide prevention and treatments.
A minimum alcohol price of 50 pence per unit could lead to a significant reduction in hospital admissions, with estimates suggesting 100,000 fewer cases per year in England. This policy change is expected to decrease consumption among underage and heavy drinkers while increasing moderate drinkers' spending slightly.
The NCAR-IDB partnership aims to assess climate risks and develop response plans in Latin America and the Caribbean. Trained scientists will predict climate change impacts and help governments develop strategies to protect society.
A recent study found that bloggers adhere to an ethical code based on standards journalists follow, with key principles including truth telling, accountability, and minimizing harm. However, the extent of their adherence depends on context and intended audience, highlighting the need for 'teeth' in ethics codes.
A recent study has discovered 27 genetic regions associated with autism spectrum disorders, revealing the complex interplay of inherited and new mutations. The research identifies multiple genes, including BZRAP1 and MDGA2, which play crucial roles in synaptic function and neurological development.
A study published in Science Express demonstrates the first definitive link between mutations in the DICER1 gene and cancer. Children with pleuropulmonary blastoma carried a mutation in one of their two DICER1 gene copies, which may disrupt normal lung development and communication.
The authors emphasize the need for an effective international response to address alcohol-related harm, citing inadequate policies and industry influence as major obstacles. Cost-effective interventions exist but require scaling up; governments, NGOs, and academia must work together to develop and implement policies.
Synaptic plasticity plays a crucial role in maintaining brain homeostasis, ensuring an effective response to challenges followed by recovery. The study provides the first set of synaptic rules for resetting homeostatic setpoints in vivo.
A large study found that stroke survivors experience a decline in functional ability over five years, with those having Medicaid or no private insurance showing the greatest decline. Factors such as age, diabetes, and severe stroke severity also contribute to this decline.
A study published in The Lancet found that excessive alcohol consumption in Russia is responsible for more than half of all premature deaths among adults, with men being particularly affected. The researchers analyzed data from three Russian cities and found that alcohol use was linked to an increased risk of deaths from accidents, vio...
A University of Minnesota study found that environmental cues trigger delayed reproduction to prolong lifespan and increase genetic impact. This discovery has significant implications for understanding human aging and developing strategies to improve health.
A new study by George Mason University researchers challenges the long-held notion that dinosaurs were massive creatures. They found that using a flawed statistical model led to overestimations of dinosaur weight, revealing some species may have been smaller than initially thought.
Case Western Reserve University has received funding to support multiple stem cell and regenerative medicine commercial, emerging, and pilot projects. The $5 million grant will help advance technologies to benefit patients in Ohio, building on previous investments that have brought in $170 million in new commercial development.
Researchers used a 'neurologger' device to record pigeon brain activity while flying over familiar terrain. The study found that pigeons respond to visual cues with distinct brain patterns, including high-frequency oscillations reflecting memory processing.
Researchers discovered that microRNA miR29 suppresses HIV replication by transporting mRNA to processing-bodies where it is stored or destroyed, reducing viral infectivity. Inhibition of miR29 enhances viral replication and infectivity.
Researchers engineered mice with a duplication of the autism-linked chromosomal region and found they exhibited behaviors associated with human autism, including poor social interaction and repetitive behavior. The study provides a valuable model for therapeutic development and sheds light on the molecular pathways underlying autism.
A new study by the University of North Carolina at Chapel Hill found that Latino adolescents who maintain strong ties to their native cultures perform better academically and adjust more easily socially. Parents who develop a strong bicultural perspective also have teen children who are less likely to face social problems.
Researchers propose that cancer stem cells could provide an important avenue for controlling cancer if targeted by new treatments. The subpopulation of malignant cells may be the root cause of cancer, offering a potential new approach for therapy.
A new study from Duke researchers demonstrates the positive impact of total knee arthroplasty (TKA) on physical functioning and motor skills in older patients with osteoarthritis. TKA recipients experienced significant improvements in mobility, motor skills, and limitations in activities of daily living.
The American Thoracic Society and European Respiratory Society have released standardized definitions and measurement recommendations for assessing asthma control, severity, and exacerbations. The guidelines provide a framework for clinicians to diagnose and manage asthma, with a focus on improving patient outcomes.
A new study on seed beetles reveals that low genetic quality males are more successful in fertilizing eggs, contrary to predictions. Females' multiple mating does not guarantee the sperm of the highest genetic male.
Researchers found breast cancer incidence fell 13.2% nationwide, with greater reductions among women in urban (-13.8%) versus rural (-7.5%) areas. The decline may be linked to HT discontinuation, which was more pronounced in rich/urban areas.
A new study from Cornell University engineers tiny containers that deliver drugs with almost 100% efficiency to targeted cells. The technique mimics a natural immune response and could be used to treat cancer, blood disorders, and autoimmune diseases.
Increasing alcohol prices and reducing availability are highly cost-effective measures to reduce alcohol-related harm. Banning advertising is also an effective strategy in settings with high amounts of unrecorded production and consumption.
A study of 577 breast cancer patients found that routine use of MRI scans was associated with delays in starting treatment and increased mastectomy rates. The study suggests that more research is needed to determine the benefits of MRI scans in evaluating breast cancer, as their disadvantages may outweigh any potential advantages.
A five-year study funded by the National Institutes of Health will examine the impact of cataract surgery on everyday life for people with dementia. Researchers aim to document how restored vision improves daily tasks and overall well-being.
A UCLA psychologist's study reveals that people with very mild Alzheimer's disease have trouble focusing on what's most important. They recall an average of just 2.8 words out of 12, with a reduced ability to be selective in recalling high-value words.
According to experts, a nationwide effort can accelerate the decline of tobacco use in the next 50 years. Researchers analyzed data from the 1960s to the present and found that smoking rates have declined steadily, dropping from 42% to 20% over six decades.
A new study found childhood physical abuse is associated with a 49% higher risk of developing cancer in adulthood. The research also identified potential psychophysiological factors that could explain the link between childhood abuse and cancer.
A study by Dana-Farber Cancer Institute found that higher selenium levels can worsen prostate cancer outcomes for men carrying a specific SOD2 gene variant. Men with the highest selenium levels and this variant had a 40% lower risk of aggressive disease, while those with the lowest levels were twice as likely to develop it.
A study found that high soy intake was associated with improved lung function and a lower risk of developing chronic obstructive pulmonary disease (COPD) in smokers. Flavonoids in soy may help protect against tobacco carcinogens, but more research is needed to understand the underlying mechanism.
Researchers at Yerkes National Primate Research Center found that humans and rhesus monkeys share a specific perceptual mechanism, configural perception, for discriminating among faces. This study suggests the human ability to distinguish faces evolved around 30 million years ago.
A new study from Tel Aviv University shows that high glycemic index foods, such as cornflakes and white bread, can cause sudden expansion of artery walls, leading to reduced elasticity and increased heart disease risk. The research provides a new mechanism for understanding how these foods affect the progression of heart disease.
Scientists have developed a novel protein stabilisation technique using nanoparticles, enabling detailed analysis of previously inaccessible membrane proteins. This breakthrough could lead to more effective drugs and open up exciting possibilities in therapeutic drug discovery.