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Science News for June 5, 2009


NEJM study points to new era in hepatitis C treatment

A Phase IIb clinical trial shows that adding a hepatitis C protease inhibitor called telaprevir to standard therapy can significantly improve the chances of being cured, with a 67% cure rate in patients treated for 24 weeks. The treatment also reduces side effects and treatment duration compared to standard therapy alone.

SourceNewYork-Presbyterian·JournalNew England Journal of Medicine·DateJun 5, 2009

Hypospadias, a birth defect of the male urethra, is not increasing in New York state

A study by researchers at NewYork-Presbyterian Hospital/Columbia University Medical Center has found no statistically significant increase in hypospadias rates in New York State during the 1992-2005 period, contradicting earlier concerns about environmental chemicals. Maternal age is a significant risk factor for the birth defect.

New technique developed to evaluate basketball players

A new technique has been developed to evaluate basketball players' performance, using mathematical models that consider multiple factors such as points scored, rebounds, assists, and relative importance. The results show that certain players excel in specific positions, highlighting the need for more nuanced evaluation methods.

SourceSpanish Foundation for Science and Technology·JournalEuropean Journal of Operational Research·DateJun 5, 2009

Rosiglitazone (Avandia) used in combination therapy for type 2 diabetes does not increase risk of cardiovascular disease or death but increases heart failure, and fractures in women

A study found that rosiglitazone, used in combination with standard diabetes treatments, does not increase cardiovascular disease or death risk but doubles the risk of heart failure and fractures, mainly in women. The study included 4447 patients with type 2 diabetes.

SourceThe Lancet_DELETED·JournalThe Lancet·DateJun 5, 2009

Geography and history shape genetic differences in humans

A new study suggests that genetic variations in humans are more closely tied to geographical and historical factors than previously thought. The research found that gene variants tend to be distributed throughout the world in patterns reflecting ancient population movements and other aspects of population history.

SourcePLOS·JournalPLOS Genetics·DateJun 5, 2009

If at first you don't succeed, let the search engine try

A Penn State researcher analyzed nearly 1 million Web searches to detect patterns of query reformulation and create models to predict them. The research found that users reformulated their search terms in 22% of queries to more precisely convey the information they were searching for.

SourcePenn State·JournalJournal of the American Society for Information Science and Technology·DateJun 5, 2009