A study by Duke University Medical Center found that only 64% of low-income women with hormone receptor-positive breast cancer filled any prescriptions for hormonal therapy within 12 months after diagnosis. The researchers also discovered that 40% of the women stopped taking their medication regularly, and 20% stopped using it altogether.
The study found a decrease in facial fracture incidence over the years, likely due to advancements in vehicle safety features. Individuals restrained with seat belts alone or with airbags were less likely to sustain facial fractures, highlighting the importance of restraint use in injury prevention.
The study found that non-genetic variation acquired during an organism's life can be passed on to offspring through epigenetic means, affecting traits such as eye outgrowths and reproductive hormones. This phenomenon has significant implications for the study of evolution, heredity, and development.
A study found that Asian Americans who adopted more aspects of Western culture were more likely to engage in sun exposure behaviors, such as deliberate sunbathing and getting more sun on weekends. This association may lead to increased risk of skin cancer among this population.
A web-based system allowing general practitioners to confer with specialists about skin conditions has been shown to reduce referrals to dermatologists by approximately 20%. The study found that in-person consultations were preventable for 39% of patients who received teledermatologic consultations, compared to 18.3% in the control group.
A Stanford University study found that disrupting the interferon pathway, a critical immune signaling mechanism, can lead to cancer progression and impaired immune response. This defect was detected in patients with breast, melanoma, and gastrointestinal cancers, suggesting a possible explanation for treatment failures.
World-renowned virologist Professor Albert Osterhaus emphasizes the importance of preparedness in the face of swine-origin flu. He stresses that there is room for improvement in influenza vaccine production and that adequate stockpiles of antibiotics, antivirals, and vaccines are crucial for effective treatment.
Researchers at Johns Hopkins University School of Medicine have discovered a natural compound that can stop malaria parasite growth, interacting with the parasite's MetAP2 protein. The compound, fumarranol, was found to be less toxic than existing medications and showed promise in treating malaria in mice.
Researchers explore Arctic river deltas as a potential source of information about past and future climate change. The sediments deposited in these delta regions can record data on sea level, productivity, storminess, and human factors affecting sediment delivery, providing valuable insights into the global carbon cycle.
A study examining employment trends in Minnesota cities with different types of clean indoor air policies found no significant economic effect on bar and restaurant jobs. Despite this, the researchers conclude that comprehensive public health policies are still beneficial for protecting employees from secondhand smoke exposure.
Researchers have developed a new 3-minute test that measures the level of citrate in fluid samples from the prostate gland to detect prostate cancer. The technique uses light energy and can provide an accurate way to screen and diagnose the disease, particularly in its early stages.
Researchers have developed a new computer simulation model that captures the human immune response to influenza type A, predicting treatment design and pandemic preparedness. The model reveals that drugs and vaccines targeting dendritic cell presentation of antigens have a significant impact on patient outcomes.
A new study found a link between childhood sexual abuse and early onset of menstruation, with 26% increased risk for 1-3 incidents of abuse. The study analyzed data from over 35,000 African-American women aged 21-69 years.
Researchers at Northwestern University have developed a Nanofountain Probe that can precisely deliver tiny doses of drug-carrying nanomaterials to individual cells. The tool enables targeted cancer treatments and improves drug delivery by reducing side effects and increasing targeting accuracy.
Researchers have developed a method to quickly identify shRNA that turns genes on and off, enabling complex genetic screens at minimal cost. The tool has the potential to revolutionize the study of gene function in mammals, paving the way for targeted therapeutics.
Researchers created a mathematical formula that incorporated equations describing tumor evolution and growth, predicting oxygen consumption rates and cell growth. The computational model was validated with human brain tumor samples and successfully mimicked natural biological tumors.
The study compares genetic structures of Arabidopsis thaliana and Persea americana to understand how the first flowering plants evolved from non-flowering plants. Researchers found significant overlap among organ types, suggesting a genetic 'fossil' that allowed for flower transformation.
INTUNIV demonstrated significant efficacy in treating ADHD symptoms, particularly in children aged 6-12 years with oppositional behaviors. The study showed improved symptom reduction on various rating scales, including the ADHD Rating Scale-IV and Clinical Global Impressions-Improvement.
Researchers found that glucocorticoids induce production of PGD2, which protects rodent hearts from ischemia/reperfusion injury. Synthetic glucocorticoids may be more beneficial for humans following a heart attack than traditional ones.
Dr. Michael Holick's work revolutionized the understanding of vitamin D and its role in disease prevention, redefining vitamin D deficiency as a national epidemic.
A new method has been found to accurately determine the intrinsic brightness of Type Ia supernovae, enabling better cosmic distance measurements. This breakthrough uses a spectroscopic ratio and eliminates uncertainty caused by intervening dust or host galaxy type.
A new study suggests that women may be more vulnerable to the harmful effects of smoking due to smaller airways and gender differences in metabolism. The research analyzed data from a Norwegian case-control study, including 954 subjects with chronic obstructive pulmonary disease (COPD) and 955 controls.
A Canadian research team has developed a lithium-sulphur battery that can store and deliver over three times the power of conventional lithium-ion batteries. The breakthrough involves using mesoporous carbon to improve the contact between sulphur and the conductor, resulting in exceptional electrochemical performance.
The London School of Hygiene & Tropical Medicine has won the 2009 Gates Award for Global Health, recognizing its commitment to leadership and cutting-edge research in resource-poor settings. The award will enable the school to expand its distance learning programme and provide scholarships.
Excess phosphorus and nitrogen from human activities harm aquatic life and ecosystems; a dual nutrient strategy is needed to tackle both issues. The study highlights the need to consider the entire freshwater-marine continuum for effective nutrient control.
Researchers have identified a potential new focus for treating osteoporosis and periodontitis by inhibiting nuclear factor-kB, a master protein controlling inflammation and immunity. This balance is crucial in bone formation and resorption.
A new study estimates that autism spectrum disorder (ASD) costs the UK more than £27 billion a year, with £2.7 billion spent on children's support and £25 billion on adults. Researchers call for increased early intervention and policy review to address these significant economic impacts.
Plant physiologists use UV LEDs to create darker, redder lettuce rich in antioxidants, potentially improving human health. The effect is most noticeable at specific wavelengths and increases with light intensity.
Researchers at the University of Georgia have discovered that laboratory rats exhibit
A new study found that former prisoners are less likely to return to jail if they expect longer sentences for future crimes. The study used Italy's Collective Clemency Bill as a natural experiment, measuring the deterrent effect of prison sentences on recidivism rates. Results show that even small increases in expected sentence length ...
A new study finds that individuals with low levels of the 'Celebrex gene' are resistant to Celebrex treatment for colon tumor prevention. High levels of colonic 15-PGDH expression are necessary for Celecoxib to prevent colon tumors.
The American Cancer Society and National Palliative Care Research Center have awarded $1.5 million in research grants to researchers studying ways to reduce suffering in seriously ill patients and their family caregivers. The studies aim to improve the quality of life for adults and children with chronic illnesses.
Treatment with surgery or an oral appliance improves obstructive sleep apnea symptoms, with success rates of 63% and 74% respectively. Surgery is considered for patients who cannot tolerate CPAP therapy, while the mandibular advancement device shows good treatment outcomes in Korean patients.
New research on cohesin binding patterns in fission yeast reveals that features thought to differentiate cohesin behaviour between organisms collectively define its overall behaviour. This suggests that cohesin's mechanisms of action might be more similar between organisms than previously thought.
Researchers discover synaptotagmin-IV (Syt-IV) regulates synaptic plasticity, keeping connections between nerve cells optimal for learning and memory. The study's findings may lead to new treatments for neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease.
Researchers discovered that sweltering summers in the southeastern US can lead to a cooling haze due to the mixing of manmade pollutants with natural compounds from forests and vegetation. This effect was found to be significant enough to outpace carbon dioxide emissions' warming effects by 2-to-1.
Researchers at Duke University Medical Center discovered neurons that mirror the attention of others, which may contribute to social deficits in autism and other disorders. The attention-mirroring neurons were found in the parietal lobe, a part of the brain dedicated to eye movements and attention.
Scientists discovered that a substance secreted by damaged skin can trigger asthmatic symptoms in mice exposed to eczema-causing agents. Early treatment of skin rash and inhibition of the trigger substance may block asthma development in young patients with eczema.
Researchers suggest 'age-responsive' actions should be integrated into risk assessments and disaster response plans to minimize harm to frail elderly people. The team proposes strategies to address the unique needs of this vulnerable group, including evacuation plans and shelter locations.
The Regenstrief Institute has developed the Indiana Network for Patient Care (INPC), allowing emergency department providers across the state to access patients' medical histories. This technology will provide critical information for best course treatment and help strategize for future events.
Researchers at the University of Oregon have developed a new method to isolate RNA from specific cells using a chemically modified gene from Toxoplasma gondii. This approach allows for precise study of gene expression and cellular differences, opening up new avenues for research in development, neurobiology, and disease studies.
A study by Beth Israel Deaconess Medical Center found that patients want full access to their medical records, are willing to make some privacy concessions, and expect computers to play a major role in their care. Patients prioritize transparency and online access over traditional face-to-face doctor visits.
Researchers found that mockingbirds can recognize individual humans who pose a threat to their nests, leading to aggressive behavior. The birds' ability to recall these threats may be key to their success in urban environments where many species struggle to thrive.
Researchers have identified a molecular link between sleep and weight gain, suggesting that targeting T-type calcium channels could be beneficial for weight loss. Additionally, studies on glucocorticoid hormones have revealed their protective effects on the heart during ischemia/reperfusion injury.
A new mathematical model developed at the University of Texas Health Science Center at Houston suggests that tumor growth and invasion can be predicted using biophysical laws. The model, which links molecular and cellular properties to tumor behavior, consistently reproduced patterns of tumor invasion observed in experiments and patien...
A Hopkins study found critical mistakes in life-saving maneuvers like chest compressions and defibrillations in children undergoing arrests. Hands-on training with simulated arrests improved fledging doctors' performance, while experience was key to success.
Researchers have discovered evidence of pre-industrial mercury pollution in the Andes, dating back to 1400 BC, and challenge current thinking on the rise of mining societies. Mercury pollution was initially caused by mine dust from vermillion production, but later increased with Inca control of mines.
A novel vaccine strategy using VLPs could provide a more robust immune response and shorter development time compared to traditional vaccines. Researchers have already made VLP vaccines that show complete protection against H5N1 and 1918 influenza viruses.
Researchers found a biological link between tumors and negative mood changes in animal models, suggesting that tumor-induced molecules may be responsible for depression. The study also showed that disruptions in gene expression and stress hormone production are associated with tumor development.
Recent research includes the documentation of Holocene rupture on major faults in Lake Tahoe Basin and evidence for a large paleolake in Western Desert, Egypt. A study on groundwater system in southern Colorado Plateau-Arizona Transition Zone also sheds light on seismic hazards in western Washington State.
Researchers at Fraunhofer-Gesellschaft have developed a fully automatic production system for two-layer skin models, which can be produced in large quantities with perfect quality. The technique has already proven its use in practice, but was previously too expensive and complicated for mass production.
The DOE JGI's Expert Review system enhances annotation quality in microbial genomes, correcting errors and improving function annotations. Researchers can access the system to review genome annotations and contribute to advancing bioenergy research and biogeochemistry.
Scientists at Washington University School of Medicine discovered a substance called TSLP, which is secreted by damaged skin and circulates through the body to trigger asthmatic symptoms. Early treatment of skin rash and inhibition of TSLP production may block asthma development in young patients with eczema.
A new study has shown that Komodo Dragons' effectiveness lies in their unique combination of serrated teeth and venom. The venom was found to be rich in toxins that prolong bleeding and induce shock in victims, allowing the dragons to weaken and immobilize their prey.
Overall median survival improved from 3.5 months in period A to 12 months in period C, despite stage of disease at presentation affecting survival. Surgical resection is the only curative treatment, but many patients present with advanced-stage disease.
Scientists at Yale School of Medicine and Hydra Biosciences have discovered that a protein called TRPA1 may be a trigger of allergy-induced asthma in mice. Inhibiting this protein with a drug known for reducing pain could also reduce asthma symptoms, providing new hope for treatment.
Researchers at Tel Aviv University have developed a pocket-size breath test that can detect the presence of malodorous bacteria, allowing users to determine if their breath is 'okay to kiss'. The test uses biomarkers in saliva to identify two distinct populations of bacteria causing bad breath.
Researchers found that curcumin, a compound in turmeric, suppresses angiogenic activity in mice fed high-fat diets, leading to reduced fat tissue growth and lower blood cholesterol levels. The study suggests potential benefits for preventing fat tissue growth in humans.
Scientists have developed a synthetic catalyst that mimics the active site of naturally occurring enzymes, which process hydrogen like platinum. The researchers created a model of the nickel-iron complex, including a bridging hydride ligand, to better understand the mechanism of hydrogenases.
Shire plc will present key scientific data on its Attention Deficit Hyperactivity Disorder (ADHD) treatments lisdexamfetamine dimesylate and investigational non-scheduled guanfacine extended release. The presentations include studies on the pharmacokinetics, duration of effects, patient experience, and response to treatment.
Researchers are exploring alternative biomasses for microorganisms to ferment into ethanol and other fuels. The goal is to unlock the sugars trapped in cellulosic biomass, making it possible to produce sustainable biofuels.
Obese heart disease patients tend to respond well to treatment and have better short- and long-term prognosis than leaner counterparts. However, the exact mechanisms behind this phenomenon are still unclear, and more research is needed to understand the relationship between obesity and cardiovascular outcomes.
A new study found that older people with lower BMI scores are 79% more likely to develop dementia than those with higher BMI scores. Those who lost weight rapidly over eight years were nearly three times more likely to develop dementia, especially if they started out overweight or obese.
A systematic review of 128 studies found that dialysis patients have abnormal levels of cadmium, chromium, copper, lead, and vanadium, but lower levels of selenium, zinc, and manganese. This imbalance may contribute to adverse clinical outcomes in these patients.
Former inmates face significant health risks without Medicaid coverage upon release, including increased drug use and mortality. States can follow New York's lead by suspending Medicaid benefits instead of terminating them, allowing for smoother re-enrollment process.
Researchers uncover Komodo dragons' venom composition, which combines teeth and venom for lethal effects, contradicting earlier theories. The venom causes severe blood loss, inducing shock in victims.
Researchers found that elevated triglycerides are significantly more likely to result in worsening neuropathy over a year. Doctors can use this predictor to address lowering lipid counts with their diabetes patients with neuropathy, similar to pursuing glucose control.
Researchers found that 79% of patients treated with bronchial thermoplasty experienced a statistically significant and clinically meaningful improvement in their quality-of-life measurements. The procedure addresses an unmet medical need, providing persistent asthma control over the year following treatment.
Researchers have developed an air-fueled battery that stores up to ten times more energy than current designs, with potential applications in electric vehicles and renewable energy. The new design uses oxygen drawn from the air during discharge, reducing the need for chemicals and increasing capacity.
A new treatment using heat therapy on lung airways reduces severe asthma attacks, ER visits and quality of life improvements. The Alair Bronchial Thermoplasty System shows promise for patients with uncontrolled asthma despite high medication dosages.
A recent study by Washington State University professor Liv Haselbach found that concrete can absorb more CO2 than previously estimated, particularly when reabsorbed into the material over time. This could lead to a lower overall carbon footprint for the concrete industry.
A study from Northwestern University finds a strong link between the cancer drug rituximab and progressive multifocal leukoencephalitis (PML), a swiftly moving and often fatal viral brain infection. The study reports 57 cases of PML in patients with anemia, rheumatoid arthritis, or lymphoma who took rituximab.
A study published in PNAS identified TRPA1 as playing a key role in allergic asthma and demonstrated that HC-030031 effectively treated the condition in mice. This breakthrough research could represent a new avenue of treatment for asthma.
Researchers found T-type calcium channels regulate body weight and sleep, suggesting a link between the two. Mice lacking these channels were resistant to weight gain on high-fat diets.
A new study from Minnesota found that partial bans on smoking in public places have no significant impact on employment in restaurants and bars. Communities with total bans had slightly fewer employees per 10,000 residents compared to those without any ban.
A new survey reveals that post-menopausal women are reluctant to discuss vaginal dryness and pain due to embarrassment, affecting up to 47% who prefer discussing symptoms with a female physician. Despite this, 67% of those treated experience improvements in quality of life and sexual activity.
Pregnant women undergoing thyroid and parathyroid surgery experience higher rates of complications, longer hospital stays, and increased economic costs compared to non-pregnant women. The study highlights the need for cautious approach and careful deliberation on benefits versus risks.
Researchers discovered that corticosteroids reduce allergic inflammation by inhibiting the nuclear translocation of GATA-3, a key regulator of cytokine expression. This finding may lead to new treatments for allergic diseases, targeting interaction between phosphorylated GATA-3 and importin-α.
Research found that Andean women's uterine artery blood flow and oxygen delivery are higher than European counterparts at high altitude, resulting in larger babies. The study suggests genetic adaptation allows Andean mothers to adapt to the high-altitude environment, protecting their fetuses from reduced growth.
Ciguatera poisoning, caused by eating large carnivorous reef fish, may have prompted Polynesian migrations out of paradise. Researchers propose that climate change and ciguatera outbreaks led to historical mass migrations of Cook Islanders from Rarotonga to New Zealand, Easter Island, and possibly Hawaii.
RISPERDAL CONSTA has been approved as both monotherapy and adjunctive therapy in the maintenance treatment of Bipolar I Disorder. The medication offers a convenient and effective choice to delay relapse, with studies demonstrating significant delays in mood episode recurrence.
Researchers discovered that only minor differences in cell proliferation timing explain the anatomical differences between owl and capuchin monkey eyes. This finding sheds light on how complex structures like the eye evolve gradually through evolution without compromising function.
The $9.16m Carbon Benefits Project aims to encourage sustainable development schemes that generate climate adaptation, mitigation and conservation benefits. The innovative web-based system will measure and model greenhouse gas emissions produced and stored in soil and vegetation.
A Stanford University School of Medicine survey finds that Asian Americans living in California are adopting unhealthy sun-exposure behaviors as they become more westernized. The study highlights the need for increased skin-health awareness among primary care physicians and people of Asian ancestry.
Researchers at University of Cincinnati have identified a new molecular pathway responsible for the rapid development of invasive prostate cancer tumors. The simultaneous inactivation of PTEN and Par-4 genes causes a synergistic effect leading to more aggressive tumors.
Researchers at MCG report breakthrough in treating acute renal failure by blocking mitochondrial fragmentation caused by vascular obstruction, trauma, chemotherapy, and toxins. This can prevent kidney cells from committing suicide and lead to acute renal failure.
Calvin B. Cotner, a retired COMSAT World Systems director, has received the 2009 AIAA Aerospace Communications Award for his contributions to advancing Earth station technology. He is being honored for his technical and strategic leadership in guiding international cooperation in satellite communications.