Princeton University will establish an energy research center with a focus on next-generation fuels and advanced engines. The center aims to optimize the design of clean fuels for transportation vehicles, tackling challenges of energy sustainability and global warming.
A study published in the American Journal of Roentgenology found that 3T MRI detected 66 malignant lesions, while mammography detected 54 and sonography detected 57. This suggests that 3T MRI is an important tool for early breast cancer detection and more accurate disease evaluation.
Researchers have identified a previously unknown form of potassium channel, Isoform 3.1, implicated in schizophrenia and linked to abnormal brain activity. Inhibiting this protein may correct disorganized brain activity without cardiac side effects associated with existing antipsychotic medications.
Studies found that even mildly premature infants have a higher risk of medically attended RSV infection, especially those exposed to supplemental oxygen. Researchers detected an increased risk even in babies born at 37 weeks.
Researchers at Northwestern University have identified a snippet of RNA called miR-7 that helps maintain uniformity in individuals. The study found that miR-7 is critical to the molecular network regulating uniformity, which can help regulate cancer cells' behavior.
Pfizer has partnered with BioMed Central to cover publication costs for its researchers, making their research results universally accessible. This move follows the lead of major funders such as the National Institutes of Health and Wellcome Trust, which have implemented policies for open access.
A one-year study found that a computer-based system significantly lowered high blood pressure in participants, reducing systolic and diastolic pressures by an average of 11.9mmHg and 6.6mmHg, respectively. The system's regular feedback and automated alerts encouraged patients to take their medication as prescribed.
UC Riverside entomologists discover that Argentine ants use a different mechanism to recognize dead nestmates, triggered by the dissipation of life chemicals. The researchers found that live ants produce both life and death chemicals, while dead ants only produce death chemicals, leading to their removal from the colony.
Research suggests that the new swine flu virus may induce a cytokine storm in otherwise healthy adults, causing fatal damage to lungs. Historical evidence also supports the possibility of severe infection and poor outcomes in young, healthy individuals.
The Lancet Editorial highlights the lack of evidence for some swine flu interventions, including culling pigs, restricting pork trade, and distributing facemasks. Experts emphasize the need for timely and accurate information dissemination to healthcare professionals, particularly in pandemic preparedness.
A new study by Uppsala University reveals a mechanism to delay the development of antibiotic resistance in bacteria. Inhibiting drug efflux pumps can mask the effect of mutations that reduce antibiotic binding, providing clues to delaying resistance development.
A new study by Karolinska Institutet shows that extra support encourages more women to cycle to and from work, increasing daily physical activity levels. The intervention group achieved a larger proportion of cycling two kilometres or more per day than the control group.
A systematic review found that hospital volume is associated with short-term mortality rates for certain cancer types, but individual studies often fail to show this association. The review concludes that case volume may be an imperfect proxy for healthcare quality and highlights the need for more direct quality measures.
Researchers at UC Davis discovered a material with unique electronic properties, exhibiting mass-like behavior in one direction and mass-less behavior in another. The discovery has potential applications in spintronics technology and could lead to new electronic devices.
Researchers discovered that the teeth contain crystals of magnesium calcite, which are smaller, harder and denser than those of pure calcite. The unique arrangement of these crystals in two different arrays allows them to be self-sharpening as they wear down.
A Purdue University study found that animals can easily access runway areas, increasing the likelihood of plane strikes. The study suggests enclosing airport perimeters with partially buried fencing and frequent maintenance to deter wildlife.
A longitudinal study found that children who watched more adult-targeted TV during childhood were more likely to become sexually active earlier in adolescence. The study tracked 754 participants from age 6 to 18 and found a 33% increase in sex among those exposed to adult content over two sample days.
Researchers found that lithium promotes DNA repair in healthy cells but not in brain tumor cells, protecting healthy hippocampal neurons from radiation-induced damage. This mechanism could provide a way to increase the radiation dose to kill tumor cells while sparing healthy tissue.
Research suggests that children who are consistently victimized by peers are more likely to develop psychotic symptoms in early adolescence. A study of over 6,400 participants found that chronic or severe peer victimization was associated with an increased risk of psychotic symptoms.
A study of over 2,000 children aged 6-18 found that those exposed to secondhand smoke had lower antioxidant levels, which can help defend against biological stresses. The researchers recommend a diet rich in antioxidants from fruits and vegetables to mitigate this effect.
A new study has found a positive association between obesity and allergies in children and adolescents, with obese kids being 26% more likely to have allergies. The study analyzed data from the National Health and Nutrition Examination Survey (NHANES) and found that IgE levels were higher among obese children.
A Florida State University researcher has won a five-year federal grant to evaluate the effectiveness of an academically focused preschool curriculum for Spanish-speaking children. The study aims to provide evidence-based tools for enhancing school readiness and promoting academic success among this growing population.
Researchers discovered that the influenza virus can paralyze the immune systems of healthy individuals, leading to severe secondary bacterial infections like pneumonia. The study found that this immunological paralysis is long-lived and specific to influenza infection.
Researchers found that clusters of schistosomiasis infections occurred in the same areas ten years after a control program ended. Long-term stability in spatial distribution suggests reviewing historic data can aid planning targeted control programs.
Researchers found that particles and molecules have a tendency to separate from each other when mixed, forming small-scale phase separation. This phenomenon is counterintuitive, as one might expect different shapes to mix well without any special interaction or repulsion between them.
A new study found that iron deficiency in womb may delay auditory neural maturation in preemies, affecting sound processing and later language development. The research evaluated 80 infants over 18 months, revealing abnormal brain maturity in those with low iron levels.
A new study published in Hepatology found that women with a history of hypothyroidism are at a significantly higher risk of developing liver cancer. The study revealed that subjects with a prior history of hypothyroidism had twice the risk of liver cancer, particularly for females, and those who had it for over 10 years had a threefold...
A phase III study found that oral rivaroxaban is more effective than subcutaneous enoxaparin in preventing blood clots (venous thromboembolism/VTE) after knee replacement surgery. The study, published in The Lancet, showed a 31% reduction in relative risk for patients given oral rivaroxaban.
Research reveals that people with emerging symptoms of Alzheimer's disease are less efficient at remembering high-value information. Clinicians may be able to train them to improve their memory by teaching strategic and selective encoding techniques.
Researchers found that obstructive sleep apnea thickens blood vessels due to NADPH oxidase enzyme activation, increasing the risk of pulmonary hypertension and other heart diseases. In mice, inhibiting NADPH oxidase reduced hypoxia-induced pulmonary hypertension, suggesting potential treatment strategies.
A study by researchers at the Children's Hospital of Philadelphia found that nearly all children admitted with concussions had abnormal brain function during testing. The hospital recommends a formal assessment before resuming exertional activities to prevent prolonging symptoms and repeat concussions.
Researchers are launching a multi-institutional effort to develop a test to detect early-stage lung cancer in lifetime nonsmokers. The project aims to create a better understanding of the biology of lung cancer and identify potential biomarkers.
Researchers have developed a microscope capable of live imaging at double the resolution of fluorescence microscopy using structured illumination. This advancement will help scientists study cellular behavior and mechanisms important for human disease with enhanced detail.
Researchers found that patients with chronic hepatitis C who have achieved a sustained viral response often still carry miniscule amounts of the virus in their bodies. These trace remainders are thought to be infectious, posing a risk to others.
Even mild acute kidney injury is associated with reduced patient and graft survival, while the strictest definition linked to poor outcomes including cardiovascular events and end-stage renal disease.
Researchers discovered the chlorophyll molecules' structure, enabling artificial photosynthetic systems. The chlorosomes contain up to 250,000 chlorophylls and have unique internal structures.
Richard Junghans, MD, has been awarded a $5.9 million grant from the Department of Defense Breast Cancer Research Program to research gene therapy techniques to modify patients' T cells and create 'designer T cells' to fight breast cancer.
The May issue of Cold Spring Harbor Protocols features a set of methods to analyze protein complexes, including Blue-Native PAGE and differential in-gel electrophoresis. Additionally, researchers can generate viral vectors using adenovirus technology for efficient gene delivery.
Researchers found that exercise programs significantly reduced lung cancer symptoms in patients who completed the study, with no deterioration in functional capacity or muscle strength. The study suggests that community-based or shorter exercise programs may be more feasible for lung cancer patients to complete.
New research by Princeton University geoscientist Gerta Keller suggests that volcanoes, not an asteroid, were the likely culprits in the demise of the Earth's giant reptiles. The study found 'biotic evidence' and 'aftermath' sediments indicating a massive die-off occurred much later than previously thought.
The Fermi telescope has detected a class of pulsars, probed gamma-ray bursts and watched flaring jets in galaxies billions of light-years away. The data may imply the presence of a nearby object beaming cosmic rays our way.
The LUMINATE trials demonstrate the ability of LX211 to significantly improve chronic eye inflammation in patients with uveitis. The study results also show a safety profile for LX211, allowing it to be suitable for chronic use as the first oral treatment for this sight-threatening inflammatory eye disease.
Researchers at the University of California, San Diego, have identified a potential new treatment for retinopathy in premature infants using JNK1 inhibitors. The study found that inhibiting JNK1 reduced abnormal blood vessel growth and vision loss in mouse models of ROP.
Researchers identified BCL2, p53, and high microvessel density as molecular factors associated with increased risk of death from prostate cancer. Additionally, a study found that news reports often sensationalize medical research, potentially misleading the public about its relevance to human health.
A randomized controlled trial found that zinc and copper supplementation was no more effective than placebo in treating acute diarrhea in children. The study's authors suggest that baseline serum zinc concentrations may not be a reliable measure of body zinc status, contributing to the lack of effect.
Research at Washington University in St. Louis found that the average age of autism diagnosis is nearly six years old, three to four years after possible diagnosis. Early diagnosis is often linked to more severe cognitive impairment and is less common for females and minority groups.
A new method for testing drugs predicts toxicity in some people, with genetic variations being key factor. The approach has potential to improve the development process and reduce costs.
Scientists at the University of Nebraska-Lincoln and RIKEN institute developed a computer simulation to design nanostructured surfaces with superhydrophobic properties. This technology can help create self-cleaning materials and water-striding robots, which are inspired by nature's ability to repel water.
A UCLA archaeologist finds that eBay's online auction house has an unexpected chilling effect on looting of antiquities, diverting villages to producing fake artifacts instead. The proliferation of these copies reduces incentives to loot and depresses the market for real items.
A study found that women with severe premenstrual syndrome are more likely to relapse after stopping antidepressant medication, and shorter treatment durations may contribute to this risk. Women who achieved symptom remission during treatment were less likely to experience a relapse.
A recent study found that infants who receive the pneumococcal conjugate vaccine (PCV) after the DPTaP-Hib vaccine experience less pain than those who receive it first. The authors suggest varying the order of vaccine administration to reduce pain.
Researchers at EMBL and PSI create ACEMBL, a new technology that produces multiprotein complexes with reduced effort and materials, speeding up structural studies and deciphering molecular mechanisms of health and disease. The system will be adapted for eukaryotic cells to study human origins and complex drug targets.
The Goldberg Center for Community Pediatric Health at Children's National Medical Center has been recognized as a national leader in improving immunization compliance rates and preventive care visits. The center achieved a significant increase in targeted immunizations from 75% to 88% among 19-35 month-old patients.
New research highlights large disparities in breast cancer care and treatment for African-American women, with a significantly lower five-year survival rate compared to Caucasian women. Socioeconomic barriers also hinder access to advanced treatments.
A study published in the Journal of Cell Biology reveals that a mutated Alzheimer's-related protein called presenilin helps form and maintain nerve cell connections. The findings suggest that failing nerve transmission might be an early step in the disease's pathology.
Howard J. Federoff has received the Bernard Sanberg Memorial Award from the American Society for Neural Therapy and Repair (ASNTR) for his significant contributions to the field of neural therapy and repair. The award recognizes his research on gene therapy and neurodegenerative diseases such as Alzheimer's and Parkinson's.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that injecting testosterone undecanoate monthly can effectively prevent pregnancy. After thirty months, the cumulative contraceptive failure rate was 1.1 per 100 men.
Children with high blood pressure are more likely to have learning disabilities and ADHD, with a four-fold increased risk. The study also found that hypertensive children have difficulties in goal-directed tasks and working memory.
Research highlights novel strategies for improving vaccine uptake and effectiveness, including social marketing and accelerating dosing schedules, to combat declining vaccination rates and disease burden
Gold nanorods can detect and treat tumors by absorbing near-infrared light, heating them up to kill cancer cells, while minimizing damage to surrounding tissues. The technology has shown promise in studies using mice, where tumors disappeared within 15 days of treatment.