A research team investigated a highly-selective EP4 agonist for treatment of gastric ulcers in mice. The EP4 agonist reduced acute hemorrhagic damage, promoted mucous epithelial regeneration, and accelerated ulcer healing. In vitro, it protected human gastric mucous cells from indomethacin-induced apoptosis.
Scientists estimate a decline in the oceans' ability to absorb manmade carbon, potentially impacting future climate. The study found that the proportion of fossil-fuel emissions absorbed by the oceans since 2000 may have declined by up to 10%.
A study published in World Journal of Gastroenterology found that green tea extract inhibited proliferation, reduced collagen content, and downregulated collagen type 1 expression in liver fibrosis models.
The National Science Foundation has awarded a nearly $1 million grant to support career advancement of women and underrepresented minority men in sciences and engineering. The program aims to foster environments conducive to recruiting, advancing, and retaining faculty in these fields.
The Georgia Institute of Technology has launched an experimental Green IT Initiative to tackle high-performance computing's growing power consumption problem. The effort, led by Sudhakar Yalamanchili, aims to develop sustainable power consumption methods using a 1,000-node IBM BladeCenter system.
New studies show that morphine can boost tumor-cell proliferation and inhibit the immune response, promoting angiogenesis and cancer metastasis. Shielding lung cancer cells from opiates reduces cell proliferation, invasion, and migration in both cell-culture and mouse models.
Researchers found that key employee migration reduces an organization's competitive advantage, even in superior organizations with established routines. The loss of strategic knowledge through employee migration allows rival firms to develop competitive responses.
Researchers create photoswitch that triggers and reverses paralysis in C. elegans worms using ultraviolet and visible light. The study demonstrates the potential of such 'photoswitches' in medicine and research applications.
Children exposed to secondhand smoke are at increased risk of vascular damage, with obese toddlers facing a four-fold higher risk compared to adolescents. The study found significant links between secondhand smoke exposure and markers of vascular injury in both toddler and adolescent populations.
A recent study examines how creating new school districts in Southern communities has led to a new form of segregation. Small, suburban districts have made underprivileged schools more vulnerable to racial segregation, locking students into declining and majority populations.
Researchers found raised levels of interleukin-1beta in the spinal fluid of recent-onset schizophrenia patients, indicating activated brain immune defense systems. This discovery offers new potential treatments for the condition, potentially interrupting its course at an early stage.
A large cohort study found that patients with type 2 diabetes mellitus have a threefold increased risk of pancreatic cancer and a twofold increased risk of gallbladder and extrahepatic biliary cancers compared to non-diabetic controls. This is the first comprehensive assessment of the risk for these cancers in type 2 DM patients.
Tropical Storm Anja has weakened, with its maximum sustained winds dropping to 63 mph thanks to NASA's QuikScat satellite. The storm is moving south-southeast at 23 mph and is expected to dissipate by the weekend, posing no threat to landmasses.
Researchers analyzed patients with a syndrome similar to NF1 and found that diagnosis may be difficult due to shared clinical findings. The study highlights the importance of molecular genetic testing to resolve diagnoses in cases of uncertainty.
Women with a history of preeclampsia may be at increased risk for reduced thyroid functioning, according to researchers. The study found that women who developed preeclampsia during pregnancy had higher levels of thyroid-stimulating hormone (TSH) and were more likely to have hypothyroidism later in life.
A UBC study suggests that finding alternative feed sources for farm animals can significantly reduce pressure on the world's dwindling fisheries, while contributing positively to climate change. The researchers propose new strategies to effect swifter and larger-scale changes in the fishing industry.
Two UNH assistant professors, Vaughn Cooper and Christopher White, received NSF CAREER grants to explore beneficial mutations in bacteria and the flow dynamics of liquefied biomass. Their research has implications for understanding adaptation, evolution, and sustainable energy solutions.
Researchers successfully delivered high-dose chemotherapy to malignant brain tumors via intra-arterial Avastin, potentially avoiding common side effects of systemic chemotherapy. The innovative technique has shown promising results in early trials and may offer a new treatment option for patients with resistant brain tumors.
Scientists at Queen Mary University of London found that insect brains are capable of intelligent behaviors like counting and categorizing, challenging the idea that larger brains are more intelligent. Research suggests that many size differences in brain size only exist in specific regions and may not lead to increased complexity.
A study by University of Chicago Press Journals found that consumers feel more comfortable standing on carpeted flooring, but their judgment of products is influenced by the distance between them and the floor. When viewed from a moderate distance, the comfort factor plays a significant role in product judgments.
Researchers found that boiling or baking fish with low-sodium soy sauce and tofu is beneficial for heart health, while eating fried, salted, or dried fish increases risk. Omega-3 intake varied by gender and ethnicity, with men who consumed more omega-3s having lower cardiac death rates.
A study published in the World Journal of Gastroenterology found that vardenafil has dose-dependent gastroprotective effects against NSAID-induced peptic ulcer. This suggests that vardenafil may be used as a potential therapeutic drug to prevent NSAID-induced gastric ulcer formation.
A Université de Montréal investigation found that over six percent of expectant mothers in Quebec use prescription drugs known to be harmful to their fetuses. The study also revealed that the abortion rate among these women is 11 percent higher than in the rest of the population.
Researchers at the Max Planck Institute have discovered how immune cells, such as white blood cells, move on various surfaces. They found that these cells use a 'clutch and wheels' system, involving cell anchors and cytoskeleton deformation to maintain constant speed, enabling them to adapt to different substrates.
A study found that depression increases mortality risk similar to smoking, but anxiety reduces it when combined with depression. Researchers suggest that help-seeking behavior may explain this pattern, and highlight the need for more attention on physical health in people with mental disorders.
A recent study published in BMC Public Health suggests that immediate and aggressive spending of $60 billion on HIV/AIDS treatment could end the epidemic globally. The research, which analyzed a leading-edge mathematical model, predicts that an accelerated approach over five years is necessary to control the spread of the disease.
A study by Stanford researchers identifies a molecular pathway that counters acetaminophen toxicity, which can lead to liver failure. The discovery highlights the potential of S-methylmethionine, a common herbal medicine supplement, in preventing liver damage caused by acetaminophen overdose.
Researchers at Cornell University used a tiny beam of light to move a silicon structure up to 12 nanometers, switching its optical properties. This technology could have applications in MEMS and MOMS, where it might be useful for creating tunable filters or preventing silicon parts from sticking together.
Researchers found a dual-brake mechanism controlling chloride transport, which calms hyperactive fetal neurons after birth. This process may benefit people with epilepsy and neuropathic pain by re-establishing natural inhibition.
The Rice University-M.D. Anderson Cancer Center program provides incoming graduate students with early exposure to translational research and clinical practice. The HHMI funding renewal will allow the program to expand to include students from M.D. Anderson's Department of Imaging Physics.
The Tulane Cancer Center is conducting a phase III randomized clinical trial for Alpharadin, an injectable treatment targeting radioactive substance Radium-223. Early trials suggest it may prolong survival for men with bone metastases from prostate cancer.
A comprehensive study of over 260 sub-fossil specimens reveals that moas should be grouped into three families and six genera, reducing the number of species to nine. The study also presents a new geological model suggesting that land-dwelling animals on the North and South Island were isolated for most of the past 20-30 million years.
A new study by Henry Ford Health reveals that heart failure patients developing kidney dysfunction in the hospital have a poor prognosis, with only 39% experiencing short-lived kidney issues. The research highlights the importance of understanding why kidney dysfunction persists in some patients and finding ways to prevent it.
A study found that choosing high-risk, high-gain options activates a key brain area associated with reward and pleasure. The researchers also discovered that the brain's response increases with the amount of money involved.
A Spanish study detects counterfeit euros using optical mouse sensors, with 79% of 2008 European coins found to be two-euro coins. The system compares images captured by the sensor with reference images from genuine coins, allowing for accurate detection.
A comprehensive program at Johns Hopkins has reduced the need for emergency airway surgery by 67% by providing a standardized cart with essential supplies and training staff on its use. The program's success story highlights the importance of organization and teamwork in improving patient outcomes.
Researchers studied amygdala development, finding that neural pathways bypassing cortex are more plastic in juvenile than adult mice. This suggests that teenagers' emotions are less precise and more irrational due to subcortical drive.
A study by Shalini Bahl and George R. Milne found that consumers engage in an inner dialogue with multiple perspectives, including a 'desirable self' that promotes positive consumption behaviors. However, this self can also lead to overstretching and burnout when allowed free reign.
The ACT study focuses on finding ways to delay or prevent dementia, including Alzheimer's disease. Recent findings highlight the role of vascular disease and controlling high blood pressure in reducing the risk of late-life dementia.
Radiofrequency ablation, a local hepatic treatment for liver metastases from colorectal carcinoma, can lead to unexplained liver hemorrhage. The procedure's increasing use with few selection criteria raises concerns about minimizing complications. Early intervention is crucial in managing these complications.
Researchers from NC State University have identified a gene called FoxJ1 that tells embryonic stem cells in the brain when to stop producing nerve cells. This discovery advances understanding of the nervous system and its development, with potential applications for conditions like Parkinson's disease and Alzheimer's.
Researchers at Vanderbilt University have successfully demonstrated the fractional quantum Hall effect in clean graphene, a two-dimensional crystalline material. This breakthrough exploits graphene's unique electrical properties to create novel devices and test theoretical models of extreme environments.
Physicists at Rice University have successfully created a Bose-Einstein condensate from strontium atoms, marking an important advancement in atomic-scale research. The achievement demonstrates the long-sought creation of a state where individual atoms lose their identity and come together to form a singular lump.
A study found that simple touch and massage techniques can significantly reduce cancer patient symptoms, with caregivers showing gains in confidence and comfort. The study suggests that family members can achieve similar results as professional practitioners by receiving brief home-based instruction.
Researchers found that mental budgets alone were insufficient for controlling overconsumption; active goals and numerical recommendations are crucial. Mental budgets succeed when consumers follow specific limit guidelines, such as weight loss programs like Weight Watchers.
A new study examines the consumption attitudes of upper-middle-class women in Turkey, finding two distinct class fractions with different consumption strategies based on childhood socialization. The more educated group focuses on Western lifestyle emulation, while the less-educated group prioritizes Turkish status symbols.
Researchers found that transplanting a potent form of adult stem cells into the heart muscle results in less pain and an improved ability to walk. The study also showed reduced episodes of chest pain in daily life.
A study published in PLoS One highlights the poor quality of diagnostic tests for TB, malaria, and HIV commercial tests, citing moderate to low quality studies with poorly reported methodologies. The researchers emphasize the need for improved test assessment to prevent incorrect diagnoses and adverse consequences.
A study led by Sandra Dunbar found that educating family members of heart failure patients about healthy eating habits can significantly reduce their sodium intake. The intervention, which combined patient and family education with support communication skills, resulted in a significant decrease in urinary sodium excretion.
A Tel Aviv University-developed dressing can eradicate infection-causing bacteria after just two days, protecting wounds until they heal. The biodegradable, antibiotic-infused material mimics skin's protective properties and helps doctors administer high doses of antibiotics locally, reducing toxicity issues.
Thalidomide's mechanism of causing limb defects has been linked to its impact on angiogenesis, the growth of new blood vessels. This understanding paves the way for developing safer treatments for diseases like Leprosy, Crohn's Disease, and AIDS.
Researchers propose EIT wave analysis as an alternative approach to measure the solar coronal magnetic field. They demonstrated that the profile of EIT wave propagation velocity can be utilized to probe the coronal magnetic field, potentially unveiling the nature of solar flares and CMEs.
Physicists at the Joint Quantum Institute have developed a technique to create entangled photons from quantum dots tweaked with a laser. This method may enable more compact and convenient sources of entangled photon pairs than presently available, revolutionizing quantum information applications.
A new study finds that night shift workers and those with frequent overtime have a higher risk of developing metabolic syndrome, which increases the risk of cardiovascular disease. The study also reveals younger officers working at night are more likely to develop this condition.
The study utilizes a viral-based gene transfer system to make Nerve Growth Factor (NGF), which helps maintain nerve cell survival in the brain. Participants will receive CERE-110 via neurosurgery or placebo surgery and undergo thorough medical examinations and cognitive testing.
The NIH has awarded $8.5 million to support research on pharmaceuticals for children, with a focus on determining outcome measures to facilitate future studies. The grants will support studies in pediatric cardiology, neonatology, and pediatric neurology, aiming to improve the quality of pediatric research.
The US received a 'D' grade on the March of Dimes Premature Birth Report Card, with over half a million newborns not receiving a healthy start. Seven states improved their preterm birth rates by reducing smoking, uninsured rates, and late preterm births.
Researchers at Purdue University and NASA found that compounds containing fluorine atoms are more efficient at blocking radiation, contributing to global warming. These compounds, such as chlorofluorocarbons, hydrofluorocarbons, and sulfur and nitrogen fluorides, have the potential to quickly slam the atmospheric window shut, unlike ca...
Global fossil fuel CO2 emissions increased by 29% between 2008 and 2000 due to growing coal use and international trade. The natural carbon sinks' efficiency has decreased, allowing more CO2 to remain in the atmosphere. This rise highlights the need for drastic reduction in global CO2 emissions.
The HEAAL study found that higher-dose losartan (150mg) reduces death or hospital admission for heart failure by 10% compared to low-dose (50mg). The high dose also showed a significant reduction in hospital admissions, with a hazard reduction of 13%.