A study published in Molecular and Cellular Proteomics identified 57 proteins that change during diabetes-induced erectile dysfunction, including those involved in cell death, fat metabolism, and sex hormone transport. These findings may lead to new diagnostic tools and drug targets for treating ED in diabetic patients.
Professor Benoît Marsan's research solved two long-standing issues in solar cell development: a corrosive electrolyte and expensive platinum cathode. His innovative solutions use new molecules and cobalt sulphide, increasing photovoltage and stability.
Researchers created a mouse model with a genetic change associated with depression to study the link between stress and disease. The study found that this mutation impairs the removal of signaling protein from brain areas regulating memory and emotional responses.
A new oral anti-cancer drug, vorinostat, is safe to combine with short-term palliative radiotherapy in patients with advanced pelvic cancer. The therapy may enhance the effect of radiotherapy and could become a component of long-term curative treatment. Patients showed tumor response and reduced side effects when treated with vorinostat.
A large study found that walking at a brisk pace (3 miles per hour) or for two hours a week significantly lowers the risk of stroke in women. The study followed 39,315 female health professionals over 11.9 years and found lower risks for total, clot-related, and bleeding strokes.
Researchers analyzed 70,000 patients and found no difference in quality of care between normal-weight and obese/overweight individuals. In fact, obese patients had higher rates of recommended diabetes care, vaccinations, and cancer screenings.
A recent study found that nearly one in five adults aged 40+ with known COPD risk factors are undiagnosed, highlighting the need for early screening and intervention. The study's authors recommend targeting high-risk patients in primary care settings to reduce mortality, morbidity, and healthcare costs.
Group Health's patient-centered IT approach results in high patient satisfaction and efficient communication with providers. Evaluations show patients value secure e-mail, phone, and online services for better care.
A universal influenza vaccination program in Ontario, Canada, reduced influenza cases by two-thirds and deaths by more than a quarter. The program's economic attractiveness was found to be comparable to targeted programs, with an estimated cost-effectiveness of Can$11,000 per quality-adjusted-life-year gained.
The study supports the utility of Chronix's serum DNA tests to predict clinical status and monitor disease activity in multiple sclerosis. The findings show that the approach can differentiate periods of active disease attacks from stable periods, providing a real-time measure of disease activity.
Scientists have successfully synthesized element 117, a superheavy element with 117 protons, by fusing calcium and berkelium. The short-lived atom is unstable but lives longer than many lighter elements, confirming theories of an island of stability on the periodic table.
A new study published by the University of Maryland Center for Environmental Science found that 20 major US streams and rivers have experienced statistically significant long-term warming, with increases averaging 0.02-0.14°F per year. This trend is most pronounced in urbanized areas, posing a threat to aquatic biodiversity and ecosyst...
A new study found that middle-aged Americans aged 50-64 reported a significant increase in mobility-related difficulties, with over 40% citing health problems as causes. The trend is concerning, as it may lead to increased need for long-term care and societal costs.
A recent study reveals Toxoplasma gondii is prevalent among Iberian Lynx, with 81 of 129 sampled felids testing positive for antibodies. The parasite was also found in captive breeding centers, highlighting the need for prevention measures.
Researchers at UCLA have created a novel desalination membrane that resists clogging, allowing for lower energy demands and increased lifespan. The membrane's surface topography and chemistry enable it to repel impurities, making it suitable for various water sources.
A defective protein in spinocerebellar ataxia type 5 (SCA5) damages nerve cells by cutting the number of synaptic terminals and disrupting intracellular transportation. The study suggests that the complex containing beta-III-spectrin, dynactin, and dynein might also snag microtubules to prevent degeneration.
Children removed from orphanages and placed in foster care experience gains in growth and intelligence, catching up with non-institutionalized peers on many measures. Caregiving environments play a significant role in this catch-up growth, with sensitivity and positive regard being key predictors.
Researchers found that only patients with a specific genetic mutation are eligible for gene therapy, which has shown promising results in treating Leber congenital amaurosis. Genetic testing can detect changes in the genome, but accurate interpretation is crucial to ensure correct treatment.
Mental health providers should prescribe exercise more often to treat depression and anxiety. Researchers found that regular exercise reduces symptoms of anxiety and depression, stress, and anger. Exercise can fill the gap for those who can't access traditional therapies due to cost or stigma.
A new survey by Donate Life America shows an increase in willingness to donate organs, but the US is still not keeping pace with the demand for transplants. The survey highlights pervasive myths about organ donation and encourages Americans to register as donors.
Researchers have discovered that an enzyme found in white blood cells can break down carbon nanotubes into harmless components. This breakthrough finding has significant implications for the future use of carbon nanotubes in medicine, potentially rendering them harmless and reducing toxicity.
A recent study found that conflicts about personal space have a negative impact on trust and communication between sibling relationships. Researchers identified two major types of conflict: physical/emotional personal space issues and equality/fairness issues.
A 95-million-year-old Cretaceous African amber deposit reveals new fossils of insects, spiders, and bacteria, providing insights into an ancient tropical forest and the diversification of flowering plants during this time. The discovery is significant, as it is the first major find from the African continent.
A new study has found a long-term relationship between childhood sleep problems and subsequent alcohol and drug outcomes. Childhood sleep problems are associated with an increased risk of substance use and substance-related problems during young adulthood.
A new study reveals that childhood cancer survivors may experience a significant decrease in life expectancy, with some facing a 10-17 year reduction. The research suggests that recent advancements in treatments and closer monitoring may improve long-term outcomes for these patients.
Researchers at North Carolina State University have developed a new approach that allows hard-to-parallelize applications to run in parallel, enabling up to 20% speed increase. This breakthrough technique breaks down programs into threads, utilizing multiple cores efficiently.
A study published in Cell Transplantation has found that using ICG to label human embryonic stem cell-derived cardiomyocytes substantially improves efforts to optically track stem cells after transplanting them into heart tissues. The labeling procedure did not impair the viability or functional integrity of the cells.
A new study by researchers at Wake Forest University Baptist Medical Center refutes the widely held belief that intentional weight loss in older adults leads to increased risk of death. The research shows that seniors who intentionally exercised and/or modified their diets to lose weight were half as likely to die within eight years of...
A new study reveals that deep-sea scavengers outcompete smaller animals for food in ocean canyons, leading to reduced biodiversity. Larger animals sense the presence of food and converge on the canyon floor, devouring all available nutrients and leaving little for other animals.
Researchers at Cedars-Sinai Heart Institute conclude that dronedarone is only moderately effective and lacks clear safety benefits. The review assesses data from the FDA approval process and compares dronedarone to amiodarone, a commonly used treatment for atrial fibrillation.
A study published in Environmental Health Perspectives found that exposure to phenols, phthalates, and phytoestrogens may disrupt the timing of pubertal development in girls. High exposure to certain chemicals was associated with early breast development, while others were linked to delayed puberty.
Researchers from the University of Delaware and Stony Brook University proposed a new grid design that can minimize the impacts of local weather on power fluctuations, making offshore wind power more consistent. The study found that connecting wind power generators with a shared power line can smooth out power output, allowing sufficie...
A double-blind randomized trial found no benefit of lithium in slowing ALS progression, contrary to initial promising results from a small pilot study. The trial involved 84 patients with ALS and showed that lithium plus riluzole did not slow disease progression more than riluzole alone.
A Barrow scientist has been awarded a major grant from the Muscular Dystrophy Association to continue his research on myasthenia gravis, an autoimmune disease that causes muscle weakness and fatigue. The $450,000 grant will focus on Th17 cells, which may play a key role in causing or intensifying autoimmunity.
Researchers find random gene expression changes during early differentiation, but stability increases by a factor of 100 after nine generations. This discovery sheds light on the mechanisms behind epigenetic inheritance and its impact on stem cell research.
A new study reveals that birds, bats, and lizards play a crucial role in maintaining forest health by controlling insect populations. By eating herbivores and their insect predators, these animals reduce plant damage by 40%, leading to a 14% increase in plant biomass.
Tropical Storm Robyn formed in the Southern Indian Ocean on April 2, with maximum sustained winds near 60 knots. The storm's strong thunderstorms and heavy rainfall are safely nested over open waters, but it is expected to weaken over the next three days due to higher vertical wind shear.
The US Department of Health and Human Services has awarded $15 million to the University of Illinois at Urbana-Champaign's Information Trust Institute to improve patient outcomes while limiting access to electronic health records, health information exchange, and telemedicine. The project aims to address security and privacy barriers i...
Researchers found that online communication reinforces local relationships, builds networks of interacting individuals, and forms ties that bind for offline communities. The intersection between online and offline worlds creates a vibrant platform for community communication and information exchange.
Scientists found that alpha cells can spontaneously reprogram into beta cells, restoring insulin production and potentially treating type 1 diabetes. The study demonstrated that removing nearly all beta cells allowed the pancreas to regenerate new ones, offering a new strategy for regenerating insulin-producing cells.
Scientists have developed a low-cost behavioral assessment that can detect changes in the progression of mild cognitive impairment (MCI) and predict Alzheimer's disease. The test measures information processing capacity, which correlates with hippocampal degradation and decline in brain function.
Researchers at Emory University have successfully developed a clinical test for XMRV, a retrovirus linked to prostate cancer, using neutralizing antibody assay technology. The test has been confirmed by two independent labs and technologies, providing confidence in its accuracy.
Researchers at Duke University Medical Center have discovered a set of naturally occurring antibodies that can block HIV's entry into certain blood cells. These polyreactive anti-phospholipid antibodies show promise as a potential new strategy for HIV vaccine design.
Childhood cancer survivors may experience a 10-year reduction in life expectancy due to late effects of treatment, according to researchers. Furthermore, social connections play a significant role in shaping alcohol consumption rates, with individuals influenced by friends and acquaintances' drinking habits.
A new study has found that oral naltrexone can reduce both alcohol- and non-alcohol-related healthcare costs for patients with alcohol-use disorders. The medication was found to be effective in reducing healthcare expenditures, particularly among those with an alcohol-related diagnosis.
Cryptococcus fungi have an expanded set of genes encoding sugar transporter molecules, allowing them to efficiently move sugar inside cells and thrive. The fungi's love for sugar may be a potential weakness, as scientists can target them by developing low-carbohydrate strategies to block infections.
Recent AGU research finds prolonged low solar activity will not offset global warming, with a potential temperature decrease of only 0.3 degrees Celsius in 2100. Heat waves have also increased in the Mediterranean region since 1960, with significant increases in number, length, and intensity.
A new study by University of Michigan scientists suggests that evolutionary genetic mechanisms underlying changes in form and function are distinct. Researchers found that genes affecting morphology (form) evolved faster than those affecting physiology (function), supporting the idea that morphological changes result from gene expressi...
A new study found that regular moderate-intensity aerobic exercise during pregnancy reduces offspring birth weight by approximately 143g, while not impacting maternal insulin sensitivity. This reduction in birth weight may lower the risk of obesity later in life.
Dr. Alecia Willis, a clinical molecular geneticist, was recognized for her platform presentation on personal medical genomics at the American College of Medical Genetics Annual Clinical Genetics Meeting. The Signature Genomic Laboratories Travel Award supports rising medical genetic researchers in the field.
Researchers have created a new type of tissue and bone scaffolding polymer that addresses long-standing limitations in grafting materials. The smart polymer combines tissue-like properties and strength, and can be reshaped to fit complex injury sites before surgery.
A new study by Oregon State University researchers found that the Swiss needle cast epidemic in Douglas-fir forests of the Pacific Northwest is intensifying, affecting hundreds of thousands of acres, and causing significant growth reduction, with older trees also being susceptible.
Therapeutic swings commonly used for autism-spectrum disorders shed metallic particles into the eyes of children, causing uncommon but preventable eye injuries. The study highlights the importance of wearing protective eyewear or modifying swing apparatus to prevent this risk.
Researchers have identified four relatively simple measures of alcohol consumption that can accurately index the genetic risk for alcohol dependence in both women and men. These findings provide significant implications for risk identification and suggest that simpler measures of drinking behavior may be sufficient to capture the same ...
A pilot study found that a rice-developed nano-bio-chip is effective in detecting premalignancies with high sensitivity and specificity rates comparable to traditional tests. The minimally invasive technique could lead to earlier detection of oral cancer, resulting in higher survival rates.
A new wind power grid could compensate for natural fluctuations in wind direction and strength, providing a smoother power supply. Researchers linked offshore wind generators with a shared power line to achieve this goal.
Children with fetal alcohol spectrum disorder (FASD) are at a high risk of developing epilepsy or seizure history, according to a new study. Researchers found that six percent of individuals with FASD developed epilepsy and 12 percent had one or more seizures in their life.
A recent study published in the Journal of Clinical Oncology found that women with breast cancer before age 55 who carry an inherited mutation in BRCA1 or BRCA2 are four times more likely to develop cancer in the breast opposite their initial tumor. The study revealed a higher risk of contralateral breast cancer among younger women wit...
Researchers at Duke University found that Peregrine's PS-targeting antibodies can block the CCR5 receptor, a key portal for HIV to gain entry into blood cells. The study showed potent ability to induce specific effects that impact viruses, inducing β-chemokines to block HIV entry.
An international expert group recommends individualized treatment for patients with type 2 diabetes, citing the need to address underlying physiological and genetic differences. The recommendations aim to improve glycemic control, minimize risk, and reduce diabetes complications by tailoring therapies to specific patient subgroups.