Researchers have discovered a genetic mutation associated with motor neurone disease that causes proteins to clump together in motor neurones, leading to their death. The new finding provides strong evidence for protein aggregation as the underlying cause of MND.
Physicists at the University of Maryland have developed a novel approach to manipulate quantum bits using an optical frequency comb. The technique allows for the creation of coherent pairs of frequencies, reducing the need for physically adjusting components and increasing the versatility of qubit manipulation.
Researchers at the US Department of Agriculture's Animal Diseases Research Unit have discovered the viral life cycle of malignant catarrhal fever (MCF), a leading cause of disease in American bison. The virus undergoes several changes inside the animal's body, targeting specific cell types at different stages of its own life cycle.
Dr. Marwan Khaled Tayeh was awarded the 2010 Richard King Trainee Award for his groundbreaking research on targeted comparative genomic hybridization array analysis. The award recognizes his contribution to the identification of deletions and duplications responsible for human diseases.
Significant increases in death rates from falls, motorcycle crashes, machinery use, and unintentional poisoning have been observed among older Americans. The overall change in injury mortality for individuals aged 65 years and older increased by three percent, with the greatest increase seen in whites.
Researchers found that 16% of 6-month-olds were obese, highlighting the need for early detection and prevention strategies. Exclusive breastfeeding and adequate fiber intake can help prevent obesity in infants.
Researchers at UMass Chan Medical School have identified a novel microRNA-mediated genetic pathway responsible for triggering vascular growth in zebrafish embryos. This discovery provides new insights into how vascular systems develop and may offer a potential therapeutic target for limiting blood vessel formation in solid cancers.
Researchers have discovered that traces of medicines can be found in fish swimming in treated wastewater. Elevated levels of the hormone levonorgestrel were found in fish blood, leading to infertility. The study highlights the impact of synthetic hormones on fish reproduction and calls for more environmentally friendly alternatives.
A Yale-led team has discovered three new genetic factors that significantly increase the risk of developing brain aneurysms. The study analyzed over 20,000 subjects and found that individuals carrying these variants are up to seven times more likely to suffer an aneurysm than those with no risk factors.
Researchers at UEA have discovered a new group of molecules that can inhibit glycosyltransferases, enzymes used by cells to create sugar chains. This breakthrough could lead to significant advances in cancer treatment and therapy.
Growing energy crops like warm season grasses and short-rotation woody crops can promote long-term carbon sequestration and provide biofuel feedstock. Removing crop residues from fields, however, can lead to soil erosion, water pollution, and reduced nutrient cycling.
Researchers from the University of Gothenburg found that women with a known Western Swedish mutation in the BRCA1 gene have an increased risk of developing ovarian cancer. The study suggests that women without this mutation do not face an elevated risk, and provides clarity for targeted screenings.
Research finds that long-distance pine pollen can travel up to 1800 miles and still germinate, making it difficult to prevent transgenic traits from spreading to wild counterparts. This has profound implications for the approval of genetically modified trees.
A team of MIT researchers has made significant progress on lithium-air batteries by identifying metal catalysts that can improve efficiency and increase energy density. The study finds that electrodes with gold or platinum catalysts show higher activity and efficiency than simple carbon electrodes.
Researchers have found that spraying low concentrations of a compound known as thidiazuron (TDZ) significantly extends the life of potted plants' leaves and flowers. In tests with greenhouse-grown cyclamen plants, TDZ-treated plants had a longer life than unsprayed plants.
Tropical Storm 23S has formed over the Southern Indian Ocean with maximum sustained winds of 39 mph. The storm is expected to strengthen and intensify over the weekend before being affected by a mid-latitude trough, potentially weakening it.
A landmark international study of over 60,000 women found that many are unaware of their risk factors for debilitating fractures, which can lead to chronic pain, reduced mobility, and increased mortality. The study emphasizes the need for improved education on osteoporosis risk factors and treatment options.
A new study explores the variability in fossil assemblages, finding that communities may be more resilient than thought. The researchers used living and fossil communities to investigate the factors affecting the low variability seen in fossil records.
Researchers found a positive correlation between individuals with a positive attitude towards physical activity and those who performed more unintentional physical activity. Unintentional activity, such as climbing stairs or walking further to reach a parking spot, can help burn extra calories.
A study found that leaving logging debris behind suppresses the growth of invasive plant species like Scotch broom and blackberry, allowing native plants to thrive. This method saves costs but may increase fire risk, making it a more favorable approach for forest management.
The TRMM satellite measured heavy rainfall totals from ex-tropical storm Paul, which left up to 11 inches of rain in northern Australia. The data confirmed significant flooding, with areas receiving between 100-200mm of rainfall and some reaching up to 300mm.
Researchers found that the amygdala distinguishes between different fear memories and retrieves them selectively. The study suggests a more sophisticated storage and recall capacity than previously thought, with implications for addressing specific fear memories.
Princeton engineers developed a technique to clarify images using rays of light scattered by clouds, human tissue, or murky water. The method, known as stochastic resonance, can potentially improve signal technologies such as sonograms, radar systems, and night vision goggles.
Researchers found that gene duplication events led to functional diversity in sunflower genes, including a gene variant that lengthened flower growth periods. This trait may have been favored by early Native Americans for domestication purposes.
Researchers have made significant findings on the state of stress in central and eastern North American seismic zones, providing insights into earthquake-generating stresses. Additionally, studies have mapped the depth domains of the Eastern Ghats Belt in India, offering clues to understanding ancient collisions.
Researchers at Princeton University have developed a new technique to produce electricity-conducting plastics, potentially lowering the cost of manufacturing solar panels. The breakthrough allows for the use of low-cost printing techniques and replaces expensive materials like indium tin oxide.
Researchers have uncovered the three-dimensional structure of a key protein found on the surface of a specific HIV-1 subgroup, providing valuable insights for vaccine design. The discovery reveals unusual autoreactivity between an anti-HIV antibody and the CD4 receptor, raising questions about potential autoimmune responses.
A new system developed by Texas AgriLife Research can automatically scan water samples and detect potential pathogens like cryptosporidium and giardia, providing results immediately. This technology has the potential to address key challenges in pathogen detection in food and water, making it accessible globally.
New research suggests the Andes rose gradually, not abruptly, due to changes in oxygen isotopes and rainfall patterns. Climate modeling experiments supported this conclusion, indicating that increased precipitation rates caused the ratio of oxygen-18 to oxygen-16 to decrease.
Using optical-coherence tomography (OCT), researchers are documenting the formation of the mammalian heart in real-time, allowing for the first time to observe the heart beat and chamber contractions. This breakthrough technology aims to shed light on developmental processes and gene mutations that cause cardiovascular abnormalities.
A physiotherapist-led exercise and education program improved wellbeing and reduced depressive symptoms in postnatal women. The study found a 50% reduction in
Researchers find NINJA protein connects JAZ proteins with TPL, blocking MYC2 activation and triggering defense mechanism. The discovery sheds light on the link between growth and stress in plants, revealing a complex molecular mechanism for regulating gene expression.
Scientific research in the Islamic world faces challenges from political fragmentation and colonialism, but institutions like KAUST aim to revive basic scientific research. New projects also focus on promoting curiosity-driven research and tackling corruption.
The NIST team has built an ultra-stable instrument for tugging on chains of atoms, achieving results that require heroic efforts at vibration isolation. The new instrument enables the direct measurement of force between two gold atoms, giving researchers a direct method to calibrate their equipment.
A study published in Value in Health suggests that extending breast cancer screening to younger women could lead to better health programs and a more balanced approach to fighting the disease. The research found that screening only older women increases unfair disparities in life expectancy, quality of life, and disease incidence.
Researchers have created the first class of reagents to potently and selectively inhibit miRNAs in C. elegans, a widely used model organism. The new reagents efficiently and specifically inhibited targeted miRNA in different tissues, including the hypodermis, vulva, and nervous system.
Researchers use tissue engineering to create healthy organs and neuronal circuits, enabling live imaging of transplanted tissues and neural activity. The protocols provide methods for monitoring tissue perfusion, cell survival, and interaction/integration, allowing for improved culturing and implantation techniques.
A new study by researchers at Uppsala University and Stockholm University found that Stone Age Scandinavians were lactose intolerant. This discovery challenges earlier conclusions about the ancestry of modern Swedes.
A study published by researchers at the University of Leeds found that successful leaders exhibit decisive behavior and remain on the group's periphery, leading others quickly. The findings have implications for managing large groups in urban environments, such as crowd evacuation scenarios.
Researchers found truncated peptides form active ion channels causing cell death and memory loss, contradicting previous effective treatments. A new approach aims to control these ion channels for an effective treatment.
Researchers developed a realistic computer model of spiny stellate cells, finding that only 30 synapses out of 6,000 firing simultaneously create reliable signaling. This contradicts the widely accepted view that neurons communicate through volleys of electrical spikes.
Researchers found that people with floppy eyelid syndrome (FES) are at a higher risk of having obstructive sleep apnea (OSA), which can lead to oxygen deprivation and other health complications. The study also highlights the importance of recognizing FES as a potential indicator for OSA and treating patients accordingly.
A new study finds that denying or ignoring racism leads to greater psychological distress among Filipino-American adults, while active coping methods can decrease distress and increase self-esteem. The study suggests that therapists should consider individual factors when helping clients develop effective coping strategies.
A 12-week self-guided program helps binge eaters stop binging for up to a year, saving an average of $447 per person per year. The program reduces costs on weight loss programs, over-the-counter medications, and supplements.
Two transplant centers report successful paired donor exchanges for living donor liver transplantation (LDLT) in ABO-incompatible cases. The program allows for compatible but unrelated donors to donate, enabling recipients to undergo LDLT with high success rates.
A recent study identifies the GLRX5 gene as essential for generating iron-sulfur clusters and maintaining normal iron levels in human cells. The protein deficiency leads to sideroblastic anemia by impairing heme biosynthesis and depleting cytosolic iron in red blood cells.
A new study found that a patient's pre-surgical health classification, as determined by the American Society of Anesthesiologists (ASA), is a leading indicator of how well they will fare after hip fracture surgery. Medical complications were more common in patients with ASA class 3 and 4, highlighting the need for close medical managem...
Researchers developed a combinatorial approach using viruses to destroy tumors, which was shown to provide substantial regression and cure of tumors in mice. By targeting tumor blood vessels, this approach could potentially treat a wide range of cancers, offering new hope for cancer treatment.
A new study published in the Journal of Thoracic Oncology found that sleeve lobectomy offers superior survival and better postoperative pulmonary function compared to pneumonectomy in selected patients. The study analyzed 210 lung cancer patients and reported lower mortality rates for those who underwent a sleeve lobectomy.
A new UCLA-led study finds that high school seniors from disadvantaged backgrounds who don't apply to college are missing out on significant financial returns. The study reveals that those with lower college probabilities score better financially, with male graduates ranked
A multidisciplinary research team at NIST has found a viable candidate for creating large-area electronics by spraying organic semiconductor material onto a surface. The material overcomes a major cost hurdle in the manufacture of organic thin-film transistors, which could lead to disposable devices.
Michigan State University environmental scientist Jianguo Liu argues that China needs strong leadership and institutional innovations to achieve sustainability. He highlights the importance of integrating natural and social science research to understand complex interactions between humans and the environment.
Researchers have created a way to implant an inorganic device into a cell wall without damaging it, allowing for up to a week of observation. The 'stealth' probe mimics natural gateways in the cell membrane and integrates smoothly into membranes, enabling electrical access to the inside of cells.
Researchers found that behavioral incentives improved attention and reduced impulsivity in children with ADHD, normalizing brain activity similar to that of control groups. Medication had the most significant effect, but combining it with rewards and incentives boosted its benefits.
NASA's Aqua satellite detected a weakened Cyclone Paul over the Gulf of Carpentaria, Australia, leading to the cancellation of all mainland weather warnings. The storm's remnants are expected to track inland and weaken further, with only coastal waters warning in effect.
A Johns Hopkins study found that more than half of donor kidneys infected with hepatitis C are discarded, despite the need among hepatitis C patients who may die waiting for an infection-free organ. The study suggests that using hepatitis C-positive kidneys could help those with hepatitis C and expand the organ supply.
Astronomers used the Fermi Gamma-ray Space Telescope to map gamma rays emitted by Centaurus A, a galaxy with a supersized black hole. The discovery confirms that microwave photons can be accelerated to gamma-ray energies through inverse Compton scattering.
A study by Cornell University found that having a husband who works 50+ hours per week can hurt women's careers and increase the likelihood of quitting. Women in dual-income households are disproportionately affected, with odds of quitting increasing by 42% for those whose husbands work 60+ hours per week.
Spinal cord injuries affect approximately 12,000 people annually and 259,000 Americans currently live with long-lasting SCI. A new study suggests that a multidisciplinary approach is most likely to achieve results in treating spinal cord injuries, leveraging expertise from several fields.
Researchers have developed a new approach to treating cancer using viruses to infect and kill cancer cells. In mice, combining this with standard therapy led to substantial tumor regression and cure. Additionally, modulating VEGF signaling allowed the cells lining tumor blood vessels to be targeted by viruses, suggesting a potential wi...