A randomized trial found that high-dose B-vitamin therapy accelerated kidney function decline and increased cardiovascular events in patients with type 1 or 2 diabetes. The study suggests that B-vitamin therapy may not be an effective treatment for slowing disease progression, and potentially poses risks for these patients.
Recent studies found that diverse microbial communities persist on spacecraft despite sterilization efforts. Escherichia coli was discovered to survive on Martian surfaces under shielded conditions or with thin dust layers.
The new clinics series provides comprehensive reviews of contemporary issues in cardiac electrophysiology, including epicardial interventions, advances in arrhythmia analyses, and antiarrhythmic drug therapy. These issues help electrophysiologists make informed clinical decisions for their patients.
Researchers at Berkeley Lab's ALS beamline 9.0.1 developed a method to image whole yeast cells with soft X-rays, achieving a resolution of 11-13 nanometers. This breakthrough enables the possibility of full 3D tomography of whole cells at equivalent resolution.
Alan McGaughey, an assistant professor of mechanical engineering at Carnegie Mellon University, has received a three-year grant to develop theoretical and computational tools for monitoring heat generation in devices. His work aims to help the Air Force reduce heat generation in operating electronics and control mechanical system tempe...
Researchers have uncovered a new pathway of microRNA generation, revealing why Argonaute2 proteins are necessary in mammals. This alternative route bypasses the Dicer enzyme, allowing Ago2 to directly mature and regulate genes.
Researchers found that lower oxygen saturation is associated with left ventricle hypertrophy and diastolic dysfunction in children with sickle cell disease. The study suggests that the beginning of adult heart disease may start in childhood, highlighting the need for further research.
A new genus and species of flying reptile, Aetodactylus halli, has been discovered in Texas, providing insights into the diversity of pterosaurs during the Cretaceous Period. The specimen is estimated to be around 3 meters long and had a unique jaw structure with 54 teeth sockets, differing from other ornithocheirid species.
A study found that consuming a non-spicy pepper analog increased fat oxidation and boosted metabolism, potentially aiding in weight loss. The research suggests that eating peppers could be a simple way to enhance weight loss efforts.
A new study suggests that an underlying cause of psychopathic behavior may be frontal lobe dysfunction, with participants showing striking similarities to those with brain damage. The research examined the emotional and cognitive aspects of Theory of Mind abilities in criminal offenders and patients with frontal lobe damage.
A comparative-effectiveness study confirms that ranibizumab eye injections in combination with laser therapy result in dramatic visual improvement for patients with diabetic macular edema. The treatment demonstrates substantial visual benefits, including a 50% improvement rate and prevention of blood vessel leakage.
Researchers have discovered a new avenue to overcome tuberculosis drug resistance by targeting an enzyme that breaks down beta-lactam antibiotics. Clavulanate and meropenem combination shows promise in sterilizing TB bacteria, including XDR-strains.
A new study by Oregon State University researchers reveals that young Americans are delaying adulthood due to economic challenges. Many are living at home longer and rely on their parents for financial support, a trend different from previous generations. The study highlights the need to strengthen institutions supporting young adults ...
Researchers found a high prevalence of complications in alcoholic cirrhosis patients at the time of diagnosis, with ascites and variceal bleeding being strong predictors of mortality. The study also showed that these complications do not follow a predictable sequence and cannot be used to determine the clinical course of the disease.
A new 16-year study found that a single flexible sigmoidoscopy examination in men and women aged 55-64 reduced bowel cancer incidence by a third. The test halved incidence in the lower bowel, leading to a 43% reduction in mortality. Researchers believe screening with this procedure could save thousands of lives.
Researchers at Mount Sinai School of Medicine have found a potential new treatment for osteonecrosis, a debilitating disease caused by steroid use. Injecting ACTH significantly reduced bone death in rabbits with osteonecrosis, promoting increased blood flow to bone cells and preventing cell death.
A pilot program involving parents and their overweight or obese children found that a family-focused Weight Watchers approach reduced body mass indexes in children. The program's success rate was 67%, with sustained improvements over the course of a year, emphasizing the importance of parental involvement in child health.
A new study found that looking at pictures of people with diseases triggers a stronger immune response, which may be beneficial for fighting off pathogens. The researchers suggest this response could have evolved as a way to prepare the body for potential infections when additional cues indicate a higher threat.
Researchers found that microbes become less efficient in converting carbon into CO2, leading to decreased carbon dioxide emissions from soils. As warmer temperatures persist, microbes decrease in number and eventually result in fewer emissions.
A binational team is monitoring the effect of the Yuma Desalting Plant on the cienega, which could affect endangered species and bird populations. The researchers are tracking water quality, water level, and vegetation to assess the impact of the plant's operation.
Researchers investigated the efficacy of acellular dermal matrix (ADM) in intestinal elongation. The study found that grafts were completely absorbed within two to three months, with severe adhesions and inflammation hindering their use. Despite these findings, ADM is believed to have potential as a scaffold for tissue regeneration.
Researchers Monica Lamm and Theresa Windus are studying complex molecular binding and aerosol particles in the atmosphere using Blue Waters supercomputer, which will deliver better results for their studies.
A new reliable method for diagnosing fibromyalgia has been developed by analyzing patients' walk parameters. The study found that patients with fibromyalgia exhibit altered motion parameters associated with psychosocial and fitness aspects, providing a potential complementary diagnostic tool.
Researchers from North Carolina State University have developed HyperSafe software to secure hypervisors against malware attacks, ensuring the integrity of underlying systems. The new approach utilizes non-bypassable memory lockdown and restricted pointer indexing to prevent code modification.
Scientists investigated the evolution of grasses by sequencing the chloroplast DNA of Anomochloa, a small genus diverging from other grasses. The study found unique and mixed features in its chloroplast genome, questioning the classification of Anomochloa as a grass.
A Purdue University scientist has discovered a long-sought gene that controls soybean stem growth, allowing for the creation of new plant varieties with desirable characteristics. The gene, Dt1, was found to be responsible for determining whether a soybean's stem continues to grow after flowering.
A study found that adding calcium in coronary arteries to traditional risk factors improves classification of risk for predicting coronary heart disease events. The researchers used computed tomography to measure the buildup of calcium in plaque on the walls of the arteries, and found significant improvements in risk prediction.
Researchers at Mount Sinai School of Medicine found that Alzheimer's pathology begins with Amyloid-Beta oligomers in the brain, rather than previously thought amyloid plaques. The study suggests that these clumps, not plaques, are toxic to brain cells and may be a major target for new treatments.
Research suggests that low to moderate alcohol consumption has no negative effects on bone health or circulating levels of vitamin D in postmenopausal women. The study also found that moderate alcohol intake does not affect markers influencing alcohol metabolism.
Researchers analyzed medical records of over 239,000 women to find no significant difference in preeclampsia, preterm birth, or other complications. The study suggests that commonly used medications can be safely administered during pregnancy.
A team of researchers from McGill/MUHC has developed a novel screening tool to diagnose Chagas disease, a parasitic disease affecting over 10 million people in the Americas. The new approach uses mass spectrometry technology to identify specific biological markers left by the parasite, enabling rapid and reliable diagnosis.
A nationwide study found that treating diabetic macular edema with ranibizumab eye injections, plus laser treatment if needed, results in better vision than laser treatment alone. At the one-year follow-up, nearly 50% of patients had substantial improvement in vision.
The American Gastroenterological Association (AGA) presents its prestigious recognition awards to distinguished gastroenterologists for their exceptional achievements. The awardees were nominated by their peers and undergo a rigorous review process before being selected, reflecting the high esteem in which they are held.
A new study by Johns Hopkins Medicine reveals that black children with chronic kidney disease have more severe anemia than white children, even when treated equally. The research suggests that genetic variations may be at play and could require tailored treatment guidelines.
A study by Duke University Medical Center found that imaging costs rose faster than overall cancer care for Medicare patients. The use of PET scans increased significantly, with a mean annual growth rate of 36-53% across six cancer types.
Researchers from Instituto Gulbenkian de Ciencia found that making ribs is an active process in vertebrates, balanced by Hox genes. They discovered a coordinated mechanism controlling the production of both ribs and associated muscles.
A new Northwestern University Feinberg School of Medicine study found that combining coronary artery calcium score (CACS) with traditional risk factors for heart disease is a better method than using traditional predictors alone to predict future heart attacks. The CACS was key in classifying people in the most extreme categories, iden...
Editors of prominent medical journals call for standardized approaches to assess limitations in comparative effectiveness research, including patient involvement and transparent reporting. The statement outlines 11 standards to improve the quality and reliability of CER studies.
A case study examining SARS' impact on China's engagement in global health diplomacy found that the epidemic exposed a fundamental shortcoming in the country's public health system. This has led to a reevaluation of China's approach to health as a global public concern, with caution against foreign interference.
Researchers discovered that reflecting on alternative scenarios where an institution did not exist can increase employee commitment to the organization. This 'near-loss' mentality fosters a positive view of current circumstances, leading to improved morale and institutional prosperity.
Research findings indicate that extracapsular lymph node involvement is a negative prognostic factor for esophageal cancer, leading to significantly worse long-term survival rates. The study suggests that this involvement should be taken into account for a revised staging system.
The U.S. Department of Agriculture has introduced two new compact oakleaf hydrangea cultivars, Ruby Slippers and Munchkin, suitable for small residential landscapes. These plants are the first compact forms of Hydrangea quercifolia to be released by USDA scientists.
A study found that at-risk children who can self-regulate behavior have higher test scores than their peers. Self-regulation skills, such as listening and paying attention, are crucial for academic success.
Research suggests extending HPV testing intervals to five years for women over 30 could significantly reduce cervical cancer cases. The study found HPV tests detect early signs of cervical cancer more accurately than current cytology screening.
The article argues that investing in neglected disease control is a more effective use of resources than maintaining nuclear arsenals. With $1 billion, the 11 nuclear power states could eliminate or control neglected infections, which account for up to 50% of global diseases.
Researchers discovered that activated farnesoid X receptor (FXR) slows the growth of tamoxifen-resistant breast cancer cells. FXR inhibition reduced survivability in both sensitive and resistant cell types, with more significant effects on the resistant MCF-7TR cells.
A new study confirms tart cherries' anti-inflammatory properties, reducing body and specific sites of inflammation, such as belly fat and the heart. This research also supports the potential health benefits of cherries in managing inflammation and lowering disease risk.
A single sigmoidoscopy examination between ages 55 and 64 significantly reduced colorectal cancer mortality by 43% and incidence by one-third in those screened. The study found a lasting protective effect of screening, with 59% of cases detected during screening and only a few post-screening detections.
According to new research, milk provides nearly half of all vitamin D intake in the American diet, with kids ages 2-18 relying on it for nearly two-thirds of their vitamin D. Experts emphasize the importance of vitamin D for overall health, including bone strength and immune system support.
Researchers found that paper wasps and honey bees rely on the same network of genes to guide their social behavior, including division of labor and brain activity. The study identified over 4,900 genes active in the wasp brain, confirming a genetic toolkit shared by both species.
Research found that long-term anabolic steroid users had weaker left ventricle function and impaired diastolic function compared to non-steroid users. Eighty-three percent of steroid users had low ejection fraction, linked to increased risk of heart failure and sudden cardiac death.
A study examining global hematopoietic stem cell transplantation (HSCT) rates found significant differences in transplant use between countries and regions. HSCT is most frequently used in countries with higher gross national incomes and governmental healthcare expenditures.
A new study published in Clinical Gastroenterology and Hepatology found that 30% of patients treated with cognitive behavior therapy experienced rapid symptom relief within four weeks, maintaining gains at follow-up examinations. Rapid responders showed lasting benefit for up to three months after treatment ended.
Recent studies suggest that cigarette smoking and high fructose corn syrup consumption exacerbate nonalcoholic fatty liver disease (NAFLD) in overweight individuals. Modifying these risk factors may improve patient outcomes for those with NAFLD, who are at risk of disease progression.
A study published in PLOS Medicine found that rural-urban migration in India is associated with rapid increases in obesity and diabetes. The research suggests that changes in migrant behavior, such as reduced physical activity, contribute to the risk of obesity and diabetes.
Researchers studied China's SARS crisis response and found image repair efforts unsuccessful due to self-contradiction. The Chinese government has improved its PR strategies but still needs work in communicating with the public.
A new photoprotein, proteorhodopsin, allows marine bacteria to harness sunlight energy and survive periods of starvation. This process enhances their survival in nutrient-depleted ocean environments.
A symposium at the American Association of Anatomists' Annual Meeting explores the evolution of human evolution through ancient mummies, skulls, and bones. Modern technology enables researchers to examine mummified remains without harming tissue, providing insights into disease evolution and death causes.
A study published in JAMA found that high-dose vitamin B therapy worsened kidney function and increased heart attacks and strokes in people with diabetes and kidney damage. However, the treatment did lower homocysteine levels, a risk factor for coronary heart disease.
Recent evidence suggests that bones and muscles are interconnected, releasing signals to affect each other's function or disease state. The discovery could lead to novel therapies for age-related muscle and bone disorders, which cost the US $14 billion annually.