A lifestyle intervention program combined with metformin XR significantly decreased BMI in non-diabetic obese adolescents, with a small but statistically significant impact observed over 48 weeks. The study suggests that metformin may have an important role in treating adolescent obesity.
The summit explored ways to use nanotechnology in medical imaging and therapy, focusing on targeting diseases such as cancer, neurological conditions, and cardiovascular disease. Experts discussed regulatory frameworks, design considerations, and future directions for this rapidly evolving field.
A new anti-inflammatory agent called ATL146e has been shown to limit and reverse the progression of graft-versus-host disease after bone marrow transplants. This breakthrough could make these potentially curative transplants safer and more widely used for individuals with inherited immunodeficiency diseases.
A study by Cincinnati Children's Hospital Medical Center reveals that the loss of a 'guardian angel' gene leads to premature birth due to altered signaling pathways in the pregnant uterus. The findings could lead to new strategies for treating and preventing prematurity.
Researchers propose reintroducing small, managed populations of wolves into national parks to enhance ecosystem biodiversity, increase plant biomass, and boost tourism. Advances in animal tracking technology and management techniques may mitigate concerns about wolf behavior and human safety.
Researchers have found that oat plants with strong crown rust resistance tend to produce higher concentrations of Avns, a type of antioxidant metabolite. The study suggests that oat breeders can select cultivars with enhanced Avn production by taking into account disease pressure during growth.
Researchers developed an innovative technique, Intelligent Outlier Detection Algorithm (IODA), to detect errors in sensitive technological systems. The algorithm can identify faulty readings or problems associated with failing sensors and isolate bad data.
Researchers at Michigan Medicine found that increased body fat in boys is associated with a later onset of puberty. The study examined 401 boys from diverse socioeconomic backgrounds and found that higher BMI trajectories were linked to delayed puberty.
Researchers argue that biologically diverse plantations can alleviate social, economic and ecological pressures on natural forests. These plantations can sequester carbon, mitigate climate change and restore ecological services. Well-planned plantations can help preserve high diversity old-growth forests.
A study published in Physical Therapy found that decreased muscle strength is associated with difficulty performing daily activities like stooping, crouching, and kneeling. Older adults with weakened trunk extensor, knee extensor, and ankle flexion muscles had significant difficulties with these tasks.
Researchers at Arizona State University have developed a plant-based therapeutic that effectively combats West Nile virus infection. The treatment, derived from tobacco plants, neutralizes the virus by binding to its surface protein, offering a promising alternative to existing treatments.
Researchers found bonobos never seem to learn how not to share, whereas chimps do as youngsters but grow out of it. Bonobos' behavior is shaped by their environment's abundance, leading to a 'Peter Pan world'. They shared like juveniles even after reaching adulthood, unlike chimps.
Researchers found that transplanted hepatocyte cells and growth factor genes rapidly infiltrate damaged livers, promoting regeneration. Prolonged HSC activation is beneficial for proliferation of transplanted cells.
UC researchers argue that citizen awareness and participation are essential for a robust cybersecurity strategy. They recommend a three-pronged approach: coordination between government agencies and business interests, engagement with the public about their role in cybersecurity, and education on safe computer practices.
Researchers are testing whether simulation driving can improve Parkinson's patients' driving skills and reduce their threefold increased risk of car accidents. The five-week training program involves simulator-based driving tests and on-road evaluations to assess the impact of cognitive-improving activities.
A new study found that adding a contrast agent to MRI improves the accuracy of detecting lymph node metastases. The researchers concluded that incorporating contrast enhancement in malignancy criteria improves diagnostic test accuracy, and histopathologic examination should still be used as a gold standard.
A new study from North Carolina State University reveals that the Norway Fund, a leading sovereign wealth fund, operates primarily driven by profit. The research suggests that other sovereign wealth funds may also be profit-driven, contradicting concerns about political motivations.
Researchers are exploring the environmental implications of nanotechnology, focusing on the fate and transport of natural and manufactured nanomaterials in ecosystems. Studies have shown that nanoparticles can be toxic if inhaled, and may undergo chemical transformations in the atmosphere, increasing their solubility and potential for ...
A new study compared two common treatment options for clubfoot – Ponseti method and surgical treatment. The Ponseti method was found to be more effective, with a lower recurrence rate and less invasive treatment required. Patients treated with the Ponseti method needed significantly less revision surgery.
A recent study by Kaiser Permanente has compared the effectiveness of two AMD drugs, ranibizumab (Lucentis) and bevacizumab (Avastin), while a global report highlights retinal vein occlusion prevalence worldwide. Additionally, research reveals that central vision impairment significantly increases the risk of falls in older adults.
Researchers at Johns Hopkins University found a link between genes and navigation abilities in humans. People with Williams syndrome, a rare genetic disorder, struggle with reorientation tasks, indicating impaired mental visualization of room layouts.
A new study by the University of Pennsylvania shows that an abstinence-only intervention for pre-teens can delay the onset of sexual activity. The program reduced self-reported sexual intercourse by 33% compared to a control group, with fewer reports of recent sexual activity among participants.