The pea aphid's genome shows evidence of duplicated genes, suggesting a 'back-up' system for genetic material. This allows for modifications through mutations, helping the aphid adapt to its environment and complex life cycles.
Researchers used gene therapy to deliver a portion of DNA that makes the SMN protein into newborn mice, resulting in improved muscle coordination and longer survival. The treatment corrected motor function, restored nerve signals, and improved overall health in mice with spinal muscular atrophy.
A systematic review found inadequate coverage of effective interventions for HIV prevention among injecting drug users globally. Only 8% of injectors have accessed needle and syringe programs in the last year, with coverage varying greatly between countries.
Researchers at Johns Hopkins Children's Center report encouraging results in children with egg allergies who consume increasingly higher doses of egg protein. The study found that more than half of the children could tolerate 5 grams of eggs without an allergic reaction, experiencing mild to moderate symptoms.
Researchers at the Salk Institute discover two genetic master switches that determine a plant's polar axis, with one group promoting root development and the other shoot growth. The study reveals an antagonistic relationship between these switches, which are regulated by multiple mechanisms to ensure proper spatial distribution.
A new investigational drug, bapineuzumab, has been shown to reduce amyloid-β deposits in the brain by 25% in patients with mild-to-moderate Alzheimer's disease. This breakthrough finding could help assess the efficacy of other drugs for Alzheimer's treatment.
Beewolves have evolved a symbiotic relationship with bacteria of the genus Streptomyces that produce nine different antibiotics, providing effective protection against various pathogens. This natural defense mechanism, known as combination prophylaxis, has been used by beewolves for millions of years to safeguard their offspring.
A new technique called Fast Relaxation Imaging enables real-time observation of protein folding and unfolding in living cells. The method reveals that proteins are more stable and their thermal denaturation is more gradual in a cellular environment compared to an in vitro setting.
A new study has identified four key aspects of immune system disturbance that contribute to the development of coeliac disease, including how T cells react to toxic wheat proteins and the body's response to viral infections. The research also suggests a shared risk between coeliac disease and other chronic immune-mediated diseases.
Researchers discovered that caddisfly larvae's underwater silk adhesive is sticky and has potential to be used as a medical bioadhesive in surgery. The silk, known as 'rock rollers,' may be useful for sticking wet tissues together, similar to using a wet Band-Aid.
A new technology delivers nicotine directly to the lungs, providing immediate relief of withdrawal symptoms and reducing throat irritation. This innovative approach combines vapor phase pyruvic acid and nicotine for a more effective and tolerable smoking cessation therapy.
A team of LMU researchers has created a genetically modified strain of pigs that consistently develop the essential symptoms of type 2 diabetes. The pigs' physiology is similar to humans', making them an ideal model system for studying the disease, testing new treatments and diagnostic methods.
Researchers found that younger patients (age 69 and younger) benefit from stenting, while older patients (over 70) are more suited to surgery. This study provides valuable risk/benefit information to help physicians choose the best carotid procedure based on individual health history.
Researchers identify a gene signature that predicts colon cancer recurrence and death, allowing for personalized chemotherapy targeting and avoiding toxic treatments.
Purple loosestrife, a destructive invasive plant, may face a reproductive penalty in northern climates. Northern populations have adapted by flowering earlier but suffer reduced seed production and smaller size.
Scientists at Rhode Island Hospital have discovered a novel mechanism of cell-to-cell communication using microvesicles, which can reprogram stem cells to behave like healthy cells. This finding offers hope for tissue regeneration and potential treatments for diseases such as cancer.
Researchers at UT Southwestern Medical Center found that blocking new growth of specific brain nerve cells increases vulnerability for cocaine addiction and relapse. Increasing adult neurogenesis may prevent addiction before it starts, potentially improving the length and quality of life for millions of drug abusers.
The Genetics/Genomics Competency Center is a free, Web-based resource providing materials on genetics and genomics for educators training nurses and physician assistants. The tool helps match existing educational resources with competencies for health professionals.
Leading researchers discuss challenges of identifying and protecting vulnerable species amidst unprecedented climate change, covering topics such as vegetation distributions, bird, insect, and marine populations. The collection provides insights into the responses of corals, amphibians, and other organisms to environmental changes.
Researchers found that smoking significantly increases the risk of an intracranial aneurysm in people who carry common gene variants. The risk increased by more than five-fold when combined with smoking, highlighting the importance of quitting to reduce genetic susceptibility.
A nationwide study found that blacks are substantially less likely than whites to know they have atrial fibrillation or use warfarin as treatment. This disparity could explain why the black population has a higher incidence of stroke and death from strokes compared to the white population.
A new study found that nearly a third of patients age 65 and older referred to a specialist do not receive treatment due to failed referrals. The study revealed that only 50% of those referred had the opportunity to receive treatment, highlighting the need for improved health information technology to address this issue.
Physicists at UW-Madison created an atomic circuit that may help quantum computing become a reality by exerting control over two atoms for a short period. The achievement uses neutral atoms to create a controlled-NOT gate, a basic type of circuit essential for any quantum computer.
Researchers at Johns Hopkins University have developed a noninvasive infrared scanning system to help doctors determine whether pigmented skin growths are benign moles or deadly melanoma. The system works by looking for tiny temperature differences between healthy tissue and growing tumors.
A new genetic test has been developed by CAMH scientists Dr. John Vincent and Dr. Muhammad Ayub to analyze CC2D2A gene mutations causing about 10% of intellectual disability cases. The test aims to provide more accurate diagnosis and offer appropriate genetic counseling for affected families.
Researchers from Catholic University of Rome discover that a non-pathogenic bacterium can trigger an autoimmune disease similar to multiple sclerosis in mice. The study suggests that environmental factors may play a role in the development of the disease, and could potentially lead to the development of a vaccine.
Researchers develop software that adjusts energy consumption based on anticipated price trends, allowing consumers to pre-cool appliances when prices are expected to rise. A mobile phone application also displays energy consumption per room and appliance, helping residents save money.
A study led by Queen's University astronomer Terry Bridges reveals that up to a quarter of the Milky Way's star clusters are foreign, originating from other galaxies. The research suggests six additional dwarf galaxies may exist within the galaxy beyond the two previously confirmed.
Researchers at Michigan State University used a new cooling method to study the reaction of iron and oxygen atoms in enzyme TauD, discovering never seen before steps that overturn conventional thought. This breakthrough has implications for understanding how enzymes function and designing inhibitors to prevent diseases.
The PRIME consortium is developing business models and techniques for cinema, television, and gaming. Experts are exploring ways to reduce costs and improve tools for post-production.
A study by a University at Buffalo School of Social Work professor found that hypnosis can significantly reduce the intensity of pain and suffering among women with metastatic breast cancer. However, it did not show significant benefits in reducing the frequency or constancy of pain episodes.
The CREST trial found that traditional surgery and stenting are roughly equal in safety and efficacy for clearing dangerous carotid artery blockages. Patients' age and medical condition should influence treatment choice.
A UAB study shows that African-Americans under 65 are more than twice as likely to have a stroke compared to Caucasians. The South also has higher stroke mortality rates, particularly in coastal states like Georgia and North Carolina.
A new study by Northwestern University recommends raising pregnancy blood sugar levels to nearly double the risk of complications for mothers and babies. The revised guidelines suggest that a fasting blood sugar level of 92 or higher poses serious risks to both mother and baby.
Researchers reveal that honeypot traps are susceptible to detection by advanced Botnet malware, allowing attackers to disable or ignore them. This vulnerability highlights the need for secure honeypot deployment and research into covert honeypot building techniques.
Researchers at the University of Pennsylvania School of Medicine have found that mixed lineage leukemia (MLL) cancer cells rely on a normal version of an associated protein to stay alive. Deleting this gene from leukemia cells blocks uncontrolled growth triggered by a fusion protein, suggesting that it is essential for MLL proliferation.
A study found that blacks are more likely to have an undiagnosed key risk factor for stroke and have a higher stroke incidence. The research also revealed significant racial and geographic disparities in stroke incidence and treatment, with blacks being less likely to receive recommended treatment to prevent stroke.
A recent multicenter cohort study reveals that magnetic resonance imaging (MRI) is substantially more accurate for early diagnosis of breast cancer than digital mammography or breast ultrasound. For young women at elevated risk, annual MRI is considered necessary and sufficient for screening.
The new ID card features an RFID chip, cryptography, and a six-digit PIN for secure access to personal data. It enables citizens to validate their identity online and use the eID function for various services like banking and shopping, promoting confidence in digital transactions.
Researchers propose limiting longline fishing in summer months and areas over 35 nautical miles from land to drastically reduce accidental loggerhead turtle captures. Using fish as bait may also help, but could affect swordfish catches.
A systematic review of literature found that micrometastases in axillary lymph nodes are associated with reduced disease-free and overall survival in breast cancer patients. The study's findings suggest that even small metastatic lesions can have a significant impact on patient outcomes.
A team at Washington University in St. Louis has identified a link between white-tailed deer populations and emerging tick-borne diseases, including human ehrlichiosis and southern tick-associated rash illness (STARI). The study used a sophisticated DNA assay to track the transmission of pathogens from wildlife to ticks.
A team of UW-Madison engineers has developed a highly efficient process that converts gamma-valerolactone into the chemical equivalent of jet fuel, preserving about 95% of the energy from biomass. The process requires little hydrogen input and captures carbon dioxide for future use.
Researchers found that when bacteria evolved defences against viral infections, the viruses adapted at a quicker rate and generated greater diversity. This study supports the 'Red Queen Hypothesis', which suggests that species are in a constant race for survival and must continue to evolve new ways of defending themselves.
A joint study by American and Kazakhstani scientists reveals that reducing adult mortality is key to recovering beluga sturgeon populations. The study suggests that limiting the take of adult and subadult sturgeon will contribute more to population growth than hatchery supplementation.
A study of over 226,000 trees reveals that species respond differently to environmental fluctuations, contrary to previous findings. This discovery sheds light on the coexistence of competing tree species and has implications for understanding invasive species invasions.
Researchers at UCLA have created a new graphene nanostructure called graphene nanomesh (GNM), which can open up a band gap in graphene and create a highly uniform, continuous semiconducting thin film. This breakthrough has the potential to enable practical application of graphene as a semiconductor material for future electronics.
A randomized trial found that remote ischemic conditioning with repeated blood pressure cuff inflations reduced heart tissue damage in AMI patients by 30%, with benefits increasing to 50% for those with most threatened heart tissue. Improved heart function and potential applications beyond AMI were reported.
Researchers at the University of Colorado Boulder have discovered a novel approach to studying Hemophagocytic Lymphohistiocytosis (HLH), a rare and deadly inflammatory disease. Mice infected with Salmonella bacteria developed symptoms consistent with human secondary HLH, including fever, anemia, and neurological signs.
Monash University scientists have developed a novel cotton-thread based microfluidic device capable of detecting diseases such as kidney failure and diabetes at an affordable cost. The device is the size of a postage stamp and can be produced using simple equipment like sewing machines.
Researchers found that CS-8958 resulted in higher survival rates and lower virus levels than oseltamivir in mouse models. The novel compound also protected mice from lethal H5N1 infection when given before or after exposure to the virus.
A study identifies five genes associated with early tooth development, finding that children with certain genetic variants tend to have delayed teeth and fewer teeth by age one. These children are also more likely to need orthodontic treatment as adults.
Researchers have developed a new nanoscale scanning technique that provides unprecedented insight into the surface of individual heart muscle cells in minute detail. The findings may lead to better-designed beta-blockers and improved therapeutic approaches for treating heart failure and abnormal heart rhythms.
A study found that contralateral prophylactic mastectomy is associated with improved 5-year breast cancer-specific survival rates for younger women with early-stage, estrogen-receptor negative tumors. However, the benefit is small and does not apply to most women with breast cancer.
Ed Lee, Air Force Office of Scientific Research's HBCU Program Manager, received a Trailblazer Award for his work in STEM education. His efforts have had a direct impact on the educational community, promoting innovation and open doors for others.
Researchers found that exergames significantly improved mood and mental health-related quality of life in older adults with subsyndromal depression. The study suggests encouraging results from using video games to improve symptoms, with over one-third of participants experiencing a 50-percent or greater reduction of depressive symptoms.
Researchers have developed a nanotechnology approach that allows for targeted and simultaneous delivery of cancer-killing drugs and genetic drugs to prevent resistance. The treatment shows promise in eliminating side effects associated with chemotherapy.
Dr Clare Scott and Dr Marnie Blewitt have been awarded fellowships worth AU$1.75 million to focus on lymphoma and breast cancer, respectively. Their research aims to improve outcomes for cancer patients by harnessing the body's natural killing machinery.
In a study of 1,056 severe stroke patients, researchers found that intracranial stenting and intra-arterial tPA were effective in restoring blood flow, with success rates of 76% and 72%, respectively. Other treatment techniques showed lower restoration rates.
A new study by Johns Hopkins scientists found that Notch-blocking drugs can kill brain cancer stem cells in mice, with a 70% reduction rate. However, further experiments suggested that additional therapies or increased dosage of Notch-blocking drugs may be necessary to target all cancer stem cells.