A study published in Cell Metabolism identifies GPIHBP1 as the key protein responsible for transporting lipoprotein lipase (LPL) into capillaries. This discovery offers new insights into the causes of hypertriglyceridemia, a risk factor for cardiovascular disease.
Researchers have discovered a new route for delivering cholesterol into the feces, revising understanding of cholesterol loss. This finding suggests that an alternative pathway may deliver cholesterol directly to the intestine through the bloodstream, potentially reducing side effects associated with bile-based cholesterol delivery.
Researchers found a significant association between acute illness complicated with hyperglycaemia and the development of type II diabetes or glucose intolerance. Patients with hospital-acquired hyperglycaemia during critical illness are at increased risk of developing diabetes, suggesting regular monitoring is necessary.
A study found that soccer experts made more foul calls when action moved right-to-left compared to left-to-right, suggesting a bias in refereeing. Researchers suggest that referees should avoid switching diagonals at halftime to prevent unfair advantages.
A new study from Purdue University found that higher protein intake can lead to weight loss in postmenopausal women, but also increases the risk of bone mineral density loss. Researchers analyzed data from two controlled diet studies and found that older women who consumed more protein through meat sources experienced faster bone loss ...
The study found that the vitamin D receptor helps regulate bacterial activity, responds to cues, and counters their presence. It also plays a key role in defending against Salmonella infection and squelching inflammation by binding to NF-Kappa B and preventing it from activating other inflammatory molecules.
Holly Morris and Randy Atkins received the IEEE-USA Award for Literary Contributions Furthering Public Understanding of the Profession. Their award includes a $1,500 honorarium for their live coverage and podcast reporting on engineering innovations.
The Society of Interventional Radiology has issued a global statement defining interventional radiology, emphasizing its importance in medical care and outlining its identity and scope. The statement, supported by 41 international societies, provides a universal framework for IR practices worldwide.
A recent study by URI researcher Mark Wood found that teens tend to increase their alcohol consumption during the summer before entering college. The study's results suggest that parents who monitor their children's activities, provide emotional support, and express clear disapproval of alcohol use can help decrease drinking and relate...
An ARS study found that there is no substantial quality difference between organically and conventionally produced eggs, contrary to common claims on cartons. The study also revealed differences in size and composition among various types of eggs, but these did not affect overall quality.
The new Keck website demonstrates advances in digital mapping by providing a customizable interface for users to access various data sets. The site combines ArcGIS Server and Google maps, offering an intuitive way to access data, and is significantly faster than comparable searches, returning results five to six times faster.
Researchers developed multicolor quantum dot staining to identify Reed-Sternberg cells, characteristic of Hodgkin's lymphoma. This method allows for rapid detection and identification of rare malignant cells from heterogeneous tissue specimens.
A randomized controlled trial found that patients with chronic low-back pain and degenerative lumbar osteoarthritis who took glucosamine for six months showed no significant difference in pain-related disability, pain, or quality of life compared to those who received a placebo. The study suggests that further research is needed to det...
Researchers found diverse marine life on the Mid-Atlantic Ridge, including a missing evolutionary link between backboned and invertebrate animals. The team discovered three new species with different colors and shapes, as well as sea cucumbers with unique swimming abilities.
New research reveals that cellular changes in fat tissue, rather than the immune system, contribute to glucose intolerance and type 2 diabetes. The study found that a specific gene, protein kinase C-zeta, promotes inflammation in fat cells, leading to insulin resistance.
A study published in the World Journal of Gastroenterology found that patients with the X+ allele of the APOB gene have a higher incidence of gallstone formation after radical gastrectomy. This is due to increased levels of TC and LDL, leading to bile cholesterol saturation and an increased risk of gallstones.
A study by the US Department of Agriculture's Agricultural Research Service found that rotational grazing and checking a lamb's eye color can minimize deworming. The researchers tested 71 lambs with the barber pole worm, finding that gel capsules filled with copper oxide wire particles eliminated the need for conventional dewormers in ...
A molecule that binds toll-like receptors doubles the early antibody response to an antigen and shifts it to a more effective IgG form. The findings support bridge immunity, which links innate and adaptive arms of the immune response.
The article discusses a new approach to breast cancer detection using microwave tomography, which is cheaper and less invasive than traditional X-ray mammography. The method uses mathematical models to reconstruct images of the breast based on electrical conductivity properties.
A recent study published in the World Journal of Gastroenterology found that stapled transanal rectal resection (STARR) is a safe and beneficial surgical procedure for patients with obstructed defecation syndrome. The procedure significantly improved symptoms of constipation, quality of life, and patient satisfaction.
A recent study by UNC researchers provides evidence that a specific gene, MAGE-11, interacts with proteins to promote androgen receptor activity in advanced prostate cancer cells. This finding opens the door to additional targets for new therapies and broader clinical applications of new drugs.
Researchers identify a protein released by neural stem cells that induces signaling in glioblastoma cells, causing them to differentiate. This discovery could lead to new therapy concepts targeting tumor stem cells and potentially destroying the aggressive brain tumors.
Researchers have successfully visualized lipid ordering in a whole, living vertebrate organism for the first time. The study reveals that membrane lipid order plays an important role in cellular processes and may be linked to human pathologies.
Researchers at NUI Galway have discovered a protein that enables cancer cells to withstand intense stress. Understanding this interaction could lead to the development of more effective anticancer drugs by blocking its function and encouraging tumor cell death.
The American Institute of Aeronautics and Astronautics (AIAA) will present several awards at the 46th Joint Propulsion Conference & Exhibit. These include the AIAA Air Breathing Propulsion Award to Bobby Berrier for his contributions to propulsion airframe integration, and the AIAA Propellants and Combustion Award to David G. Lilley fo...
A new study found that depressed patients who receive more competent therapy show significant symptom improvement. Therapist competence was particularly important for patients with anxiety and early onset depression. While competence predicted better outcomes in the short-term, its impact waned over time.
Researchers found that anxious conditions cause participants to become more engaged in their ideals and extreme in their religious convictions. The findings suggest that bold but vulnerable people gravitate to idealistic and religious extremes for relief from anxiety.
Researchers at the University of Adelaide are exploring ultrasound to combat blue-green algae blooms in water supplies, a significant global problem. They aim to develop an environmentally friendly and cost-effective method using low-amplitude ultrasound to immobilize the algae without releasing toxins.
Researchers create nanoparticle that effectively delivers genetic material into cells, outperforming existing methods. The device, a vector, is between 2 ½ and 10 times more effective than other experimental materials, according to the research.
A study by ISU researcher Diane Debinski found that drought conditions could lead to a shift from flowering plants to shrubs in montane meadows. This change could impact wildlife populations, including elk, bison, and pollinators like butterflies. Medium-moisture meadows may be particularly vulnerable to climate change.
A study published in the Journal of Neurophysiology found that rejection by a romantic partner activates brain areas associated with motivation, reward, and addiction. This can lead to extreme behaviors like stalking, homicide, and suicide during break-ups.
Researchers achieved unprecedented pressures, temperatures, and time scales to study metastable states of argon under ultra-high pressure. This technique allows for direct comparison with molecular dynamics simulations and expands our understanding of planetary interiors and exotic behavior.
Anthropologists analyze farmers branch texas revealing that immigrants are perceived as a threat to American identity, not just race but also class status. The study shows how immigrants changing their communities make whites react with anti-immigrant legislation.
The Framingham Heart Study has had a profound impact on the understanding and prevention of cardiovascular disease. The study's findings have led to significant reductions in cardiovascular mortality rates worldwide, particularly in the United States. Its legacy continues to shape public health initiatives globally.
Rutgers researchers have discovered the genetic basis for a hard kernel in quality protein maize (QPM) corn, which is essential for economical and nutritious food crops. The findings could lead to better hybrids and increase the supply of this nutritional staple in developing countries.
A study at a small private high school in Rhode Island found that delaying school start time by 30 minutes improved adolescent alertness, mood, and health. The researchers observed significant increases in sleep duration, decreases in daytime sleepiness, and improvements in motivation.
Research suggests that small and isolated reefs are more susceptible to local species extinctions due to variable fish populations. Larger, connected habitats see fewer fluctuations in population sizes, making them more resilient to changes.
A study using fMRI found that looking at photos of a former partner stimulated key brain areas involved in motivation, reward and addiction. The brain's attachment system showed signs of recovery over time, suggesting hope for those coping with rejection.
A new Policy paper argues that the estimated $30 billion needed to improve maternal, neonatal and child health is insufficient due to overlooked service delivery costs. Donors need a more realistic understanding of the funding required to achieve MDG targets for child and maternal health.
Researchers at Vanderbilt University Medical Center have discovered that water increases the activity of the sympathetic nervous system, raising alertness, blood pressure, and energy expenditure. Drinking water may also reduce fainting responses in blood donors by 20 percent, according to the study.
A 50-year study on Isle Royale has discovered a significant link between osteoarthritis in moose and early malnutrition, which also affects humans. The research found that moose experiencing malnutrition as young adults are more likely to develop arthritis later in life.
A case report describes a rare instance of intrahepatic clear cell cholangiocarcinoma, highlighting its distinct characteristics and low risk of metastasis. The cancer's unique cell structure and lack of mucin production set it apart from conventional HCCs.
A team of researchers from North Carolina State University has developed a new method for determining the sex of skeletal human remains with high accuracy. The technique uses three-dimensional imaging technology to analyze the shape and size of the pelvis, identifying over 20 key anatomical landmarks that can help determine a body's sex.
Avello Bioenergy Inc., founded by Iowa State students Jared Brown, Cody Ellens, and Anthony Pollard, utilizes fast pyrolysis technology to produce bio-oils for various industrial applications. The company's goal is to replace petroleum-based materials with renewable alternatives.
Researchers studied the bacterial community structure in four environments of the Tablas de Daimiel National Park, revealing similarities and differences between them. The study found 265 new phylum groups, including those related to Proteobacteria, which are abundant in the superficial sediment sample.
African children suffer from an estimated 656 million fevers annually, with many cases likely due to non-malarial causes. A new study estimates that only 60-103 million of these fevers are caused by the most dangerous form of malaria.
A new study published in Genetics found that mutations in 10 different genes of worms can extend lifespan without reducing oxidative stress. This discovery challenges the long-held notion that oxidative stress is responsible for aging and suggests a slow rate of metabolism may be key to increasing longevity.
ATV accidents result in severe head and spine trauma, costing $3.24 billion annually, with children under 20 years old accounting for 42% of these injuries. The study highlights the need for improved ATV stability, increased helmet use, and rider training to reduce the risk of such accidents.
Researchers have created a nano-sized light mill motor that can control rotational speed and direction by tuning incident light waves. The motor's power density is high, and it can be used to drive micro-scale objects, enabling new applications in nanotechnology and biology.
A study by Dr. David Hibbard and Dr. Duane Buhrmester found that competing to win is detrimental to teenage girls' social relationships and well-being, while competing to excel has no gender differences in its effects. Competing to excel benefits both genders, improving self-esteem and reducing depression.
A multi-institutional study found that extended use of anti-clotting drug enoxaparin significantly reduced the chances of blood clots in bedridden patients, especially those over 75 and female. The treatment also increased bleeding risk slightly.
AquaLux 3D uses precisely controlled water droplets to create 3D images in water, allowing for unique effects like video games on falling water. The technology can also enable physical interaction with the display.
Studies found higher and lower levels of genes regulating spine plasticity in individuals with schizophrenia. These alterations may contribute to layer-specific deficits in dendritic spines, a structural abnormality relevant to the disorder. Further research aims to develop new treatments targeting these disturbances.
Researchers used computer simulations to study the possible spread of the Deepwater Horizon oil spill in the Atlantic over a year. The study found that about 20% of the initial particles had been transported through the Straits of Florida and into the open Atlantic by October 2010.
A new study reveals that shorter leukocyte telomere length is associated with a significantly increased risk of developing cancer and dying from cancer. Participants with the shortest telomere lengths had approximately three times the risk of cancer compared to those in the longest group.
A study found significant variability in 5-year patient survival rates for lung transplantation centers in the US, with risks of death ranging from 30% lower to 70% higher. Despite controlling for procedural volume, center performance remained significant, suggesting true differences in quality of care.
The Genomic SQueeZ (G-SQZ) compression technique developed by TGen can compress genomic sequencing data by up to 80 percent, reducing storage needs and costs. This technology allows for selective content access and maintaining the relative order of the data.
Researchers at TGen have found a way to revive chemotherapy in ovarian cancer patients who no longer respond to conventional treatment. By inhibiting the CHEK1 protein, they were able to make these cells sensitive again to cisplatin, a widely used platinum-based chemotherapy drug.
Actin capping protein (CP) regulates filament elongation by capping the dynamic end of the filament. Two regulators, V-1 and CARMIL, modulate CP activity in different manners. The new study reveals that CARMIL uncaps filaments by suppressing twisting movement required for tight-barbed end capping.
A multidisciplinary team observes single-molecule interactions of bistable rotaxanes functioning in their native environment, enabling detailed studies of molecular machines. This breakthrough enables greater understanding of how they interact with their neighbors and might work together in nanoelectromechanical devices.