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Science News for March 15, 2010


The sexual tug-of-war -- a genomic view

A study on fruit-flies published in PLOS Biology found that genes beneficial to males are detrimental to females, and vice versa. This genetic conflict maintains genetic variation within species by regulating sex-specific characteristics and strategies, such as resource acquisition for reproduction.

SourcePLOS·JournalPLOS Biology·DateMar 15, 2010

Exploring status quo bias in the human brain

A study by UCL scientists found that people tend to accept the status quo and avoid making complex decisions, even when it leads to errors. The study used fMRI scans to examine the neural pathways involved in 'status quo bias' and discovered a key role for the subthalamic nucleus in overcoming this bias.

SourceUniversity College London·JournalProceedings of the National Academy of Sciences·DateMar 15, 2010

Timing is (almost) everything

Researchers at the University of Washington found that memory for visual scenes is not determined by attention level or scene content, but rather by when the scene is presented. This suggests a brain mechanism that automatically encodes certain visual features into memory at behaviorally relevant points in time.

SourcePLOS·JournalPLOS Biology·DateMar 15, 2010

Fruit flies and test tubes open new window on Alzheimer's disease

A team of scientists discovered a molecule that can prevent a toxic protein involved in Alzheimer's disease from building up in the brain. Using fruit flies engineered to develop a fly equivalent of Alzheimer's disease, they showed that the same molecule effectively cures the insects of the disease.

SourcePLOS·JournalPLOS Biology·DateMar 15, 2010

3-D cell culture: Making cells feel right at home

A new 3-D cell culture technique using magnetic forces has been developed, allowing for the growth of cells in 3-D. This method promises to provide more accurate preclinical drug tests and better cancer research outcomes by mimicking the body's natural tissue structures.

SourceRice University·JournalNature Nanotechnology·DateMar 15, 2010

How plants put down roots

Scientists have discovered how plants form their first roots by identifying key genes and hormones involved in the process. The discovery of transcription factor MONOPTEROS and its role in activating genes TMO5 and TMO7 could lead to breeding plants with improved root systems.

SourceMax-Planck-Gesellschaft·JournalNature·DateMar 15, 2010

Study: Grass, fungus combination affects ecology

A six-year study by ecologists at Rice University and Indiana University found that a symbiotic fungus living inside fescue can have far-reaching effects on plant, animal, and insect communities. The research suggests that cooperative microorganisms play a significant role in ecological diversity.

SourceRice University·JournalJournal of Applied Ecology·DateMar 15, 2010

A better genetic test for autism

A large study finds that chromosomal microarray analysis has about three times the detection rate for genetic changes related to autism spectrum disorders (ASDs) than standard tests. The test detects tiny sub-microscopic deletions or duplications of DNA sequences, offering greater resolution than standard karyotyping.

SourceBoston Children's Hospital·JournalPEDIATRICS·DateMar 15, 2010

Autism Consortium study in Pediatrics shows CMA finds more genetic abnormalities than current tests

The Autism Consortium study reveals that chromosomal microarray analysis (CMA) has the highest detection rate among clinically available genetic tests for autism spectrum disorders. CMA identified 18.2% of patients with deletions or duplications, compared to 2.23% and 0.46% for standard testing methods. The study recommends CMA as part...

SourceAutism Consortium·JournalPEDIATRICS·DateMar 15, 2010

Trauma of war doubles asthma risk among civilians

Research suggests that trauma from war increases asthma risk, with twice the likelihood of development in those most traumatised. A study of 2000 Kuwaiti civilians aged 50-69 found a direct correlation between trauma and asthma risk.

SourceBMJ Group·JournalJournal of Epidemiology and Community Health·DateMar 15, 2010

How muscle cells control fatty acid uptake

Researchers at Karolinska Institutet identified the role of VEGF-B protein in regulating fatty acid transport proteins in blood vessel walls, leading to increased fat intake and potential new treatments for metabolic diseases. The study found that blocking VEGF-B signalling may reduce insulin resistance and blood glucose levels.

SourceKarolinska Institutet·JournalNature·DateMar 15, 2010

Insurance status of gunshot trauma patients affects mortality outcomes

A study published in the Journal of American College of Surgeons found that uninsured gunshot trauma patients had a higher mortality rate than insured patients. After adjusting for demographics and injury severity, the odds of dying from a gunshot trauma were 2.2 times greater for uninsured patients. This disparity underscores the need...

SourceWeber Shandwick Worldwide·JournalJournal of the American College of Surgeons·DateMar 15, 2010

Robot teaches stroke survivors

Researchers developed a 'Braccio di Ferro' robot to assist patients in learning arm movements again. The interactive robot helps patients perform correct movements, promoting motor system learning and improving movement ability.

SourceBMC (BioMed Central)·JournalJournal of NeuroEngineering and Rehabilitation·DateMar 15, 2010

Study: Today's youth aren't ego-driven slackers after all

A study analyzing nearly half a million high school seniors over three decades challenges the notion that today's youth are selfish and egotistical. The research, co-authored by Michigan State University psychologist Brent Donnellan, finds that teens today share similar levels of happiness and satisfaction with previous generations.

SourceMichigan State University·JournalPerspectives on Psychological Science·DateMar 15, 2010

Researchers identify a gene that may play a key role in atherosclerosis and other diseases

A study identifies HuR as a critical regulator of an inflammatory response in cells experiencing mechanical and chemical stresses, promoting the expression of genes that support atherosclerosis. Reducing HuR levels inhibits the inflammatory response and may lead to new treatments for metabolic diseases associated with inflammation.

SourceGeorgia Institute of Technology·JournalProceedings of the National Academy of Sciences·DateMar 15, 2010

To the Antarctic or Brazil for new feathers

Researchers discovered that thin-billed prions visit the Antarctic waters for 90% of their molting period, while some individuals moulting further north off South America's coast. This flexibility allows them to adapt to unpredictable weather conditions and survive in vast ocean areas.

SourceMax-Planck-Gesellschaft·JournalBehavioral Ecology and Sociobiology·DateMar 15, 2010

Surgeons use neck muscle, surrounding tissue as lip implant

A new procedure using grafts of muscle and connective tissue from the neck has resulted in improved appearance for at least two years. The amount of vermilion showing increased by an average of 20 percent to 24 percent, while the average projection of the upper and lower lip increased by an average of 0.9 to 0.99 millimeters.

SourceJAMA Network·JournalArchives of Facial Plastic Surgery·DateMar 15, 2010

1 gene lost = 1 limb regained?

Researchers from The Wistar Institute demonstrate that mice lacking the p21 gene can regenerate lost tissue, forming a blastema and replacing damaged cells with healthy ones. This discovery provides evidence of a link between cell division control and tissue regeneration, opening up possibilities for accelerating healing in humans.

SourceThe Wistar Institute·JournalProceedings of the National Academy of Sciences·DateMar 15, 2010

Embargoed news from Annals of Internal Medicine

Researchers found a persistent excess risk of death after hip fractures, especially in men, which does not return to pre-fracture levels even after 10 years. Additionally, an empirical study explored the ethics of payment for kidney donation, finding no association between price and willingness to donate across income levels, but highl...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateMar 15, 2010

Wealth buys health -- even in China

A new study from North Carolina State University finds that the health gap between rich and poor people in China is getting narrower across generations, unlike the US where it widens. Researchers analyzed data from over 7,000 adults to track changes in health over 13 years.

SourceNorth Carolina State University·JournalAmerican Sociological Review·DateMar 15, 2010

Driving retirement for seniors

As one in four Canadians will be 65 or older by 2025, the need for safe driving retirement programs is growing. Municipalities and governments can develop solutions such as car pooling incentives, subsidized shuttle services, and urban planning to help seniors continue driving safely.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateMar 15, 2010

Inappropriate uses of frozen plasma

A recent commentary in the Canadian Medical Association Journal highlights inappropriate uses of frozen plasma, with 45% to 48% of audited transfusions found to be misuse. Experts recommend introducing measures to promote alternative use and screen orders against guidelines to improve practice.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateMar 15, 2010

JCI online early table of contents: March 15, 2010

Researchers have made significant progress in treating spinal muscular atrophy with targeted gene therapy, improving muscle strength and coordination. Additionally, a new approach to treating Duchenne muscular dystrophy heart disease has been discovered using membrane-sealing poloxamer. Furthermore, a cancer drug has shown promise in m...

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 15, 2010

Monkeys choose variety for variety's sake

In a series of experiments, capuchin monkeys were given tokens to choose between their favorite food or a buffet of options. They consistently opted for the variety tokens, even when the favorite food was included in the assortment. This suggests that these animals have an innate desire to seek variety in their diet. The findings have ...

Accelerating decisions to adopt routine vaccination; COPD a growing problem

The study analyzed data from 147 countries to identify factors that influence the time taken to introduce routine vaccination. Vaccine price and GAVI eligibility were found to be associated with quicker decisions to adopt vaccination, speeding up the process by 63% and 50%, respectively. Meanwhile, Dr. Peter Barnes discusses the growin...

SourcePLOS·JournalPLOS Medicine·DateMar 15, 2010

Emerging interventional radiology treatment with drug-eluting stents saves limbs

Drug-eluting stents have shown promising results in treating peripheral arterial disease (PAD) patients with critical limb ischemia, rivaling bypass surgery in primary patency rates of up to 81.8% and freedom from major amputation of up to 90.6%. The treatment offers a safe and effective solution for tiny blocked arteries below the knee.

SourceSociety of Interventional Radiology·JournalJournal of Vascular and Interventional Radiology·DateMar 15, 2010

Urged on by urchins: How sea lilies got their get-up-and-go

Researchers found that sea urchins prey on crinoids, a type of marine animal known as sea lilies, and suggested that these interactions drove the development of motility in sea lilies. The study, published in PNAS, provides evidence for an evolutionary arms race between predators and prey dating back over 200 million years.

SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateMar 15, 2010