A mega-flood from a giant ice sheet in North America triggered the Younger Dryas cold snap, causing Europe's temperatures to plummet. Fresh water mixing with the Arctic Ocean led to the shutdown of the Gulf Stream, resulting in prolonged glacial temperatures.
Solid pseudopapillary tumors of the pancreas are rare indolent neoplasms typically occurring in young females. The symptoms were non-specific and nearly one-third of patients were asymptomatic, making misdiagnosis common. Extended resections can potentially cure SPTs, with a favorable prognosis even after recurrence or metastasis.
Research finds that occupational exposure to synthetic fibers and petroleum products before mid-30s may treble the risk of developing breast cancer after menopause. Women exposed to these chemicals have a seven-fold increased risk, with risks magnified by each additional decade of exposure.
A four-year international trial found that dutasteride reduced the chances of being diagnosed with mid-range aggressiveness tumors, which account for most prostate cancers. The drug was effective at reducing the risk of medium-grade tumors by 31.4% in men with a family history of prostate cancer.
The study reveals that Mycobacterium tuberculosis uses small RNAs to subtly tweak bacterial production in response to environmental signals, enhancing its survival. This understanding can lead to the design of new drugs targeting persistent TB forms.
Researchers found that dehydrin proteins play a key role in helping plants like the resurrection fern survive up to 95% water loss, allowing water to act as a lubricant between cell walls. This discovery could lead to developing drought-resistant crops by localizing and transferring the dehydrin gene.
A meta-analysis found that the ATG16L1 variant is associated with a higher risk of Crohn's disease and ulcerative colitis. The study also suggests a role for autophagy in IBD development, highlighting the need for further research on the gene's etiology.
A study found that teens with a history of crack or cocaine use are six times more likely to engage in unprotected sex, putting them at increased risk for HIV. The researchers suggest that crack cocaine appears to have a significant influence on risky teen behaviors.
Researchers found that certain buckyball configurations, such as the tris configuration, caused premature senescence in human skin cells. This could lead to disease development if not properly understood. The study provides early foundations for worker protection and highlights the need for federal regulations on nanomaterial use.
A study published in the Journal of Gastroenterology found that the current ALT threshold value for detecting liver disease in children is unknown, leading to incorrect interpretations. Researchers developed sex-specific thresholds using data from the National Health and Examination Survey, which improved detection rates by 70-80%.
A new microchip-based device enhances rapid and comprehensive analysis of circulating tumor cells, revealing key biological properties. The improved system allows for better monitoring of prostate cancer treatment responses.
A team of scientists, including UH biologist Preethi Gunaratne, uncovered the genome of the zebra finch, which may help people with speech impairments and learning disabilities. The study found that microRNAs play a crucial role in song learning and memory in zebra finches.
A new model suggests that certain forests become net carbon generators when defoliated, a shift that could impact climate change mitigation. The research uses computer simulations to estimate seasonal carbon exchange rates and find that deforestation can lead to a decline in carbon absorption by up to 25%.
Research finds that postadoption depression in adoptive parents is linked to unmet or unrealistic expectations. Adoptive parents may experience struggles with bonding, feelings of guilt and shame, and confusion over their emotions. Empowerment and support can help alleviate these issues.
Researchers at EMBL identified almost 600 human genes involved in mitosis through high-throughput imaging and computer analysis. The study provides a rich resource for scientists to investigate the molecular workings of cell division.
UT Southwestern researchers discovered that new brain nerve cells play a crucial role in stress resilience. Mice susceptible to stress exhibited enhanced neurogenesis, with surviving cells surviving longer than those produced by resilient mice.
A CU-Boulder team has made history by smashing subatomic particles together at unprecedented energies, with a combined collision energy of 7 trillion electron volts. The experiment is aimed at uncovering secrets about dark matter, dark energy, gravity, and the fundamental laws of physics.
Researchers at Purdue University have identified a hidden plant pathway that produces an essential amino acid called phenylalanine. This discovery could lead to increased nutritional value in food and improved biofuel production by reducing lignin content.
Bile secretions in the small intestine send signals to disease-causing gut bacteria, enabling them to adapt and prepare to cause disease. The presence of bile triggers genes that increase iron uptake, a crucial nutrient for bacterial growth.
Mariam El-Ashmawy, a UT Southwestern Medical Center student, has been awarded a $44,000 annual fellowship from the Howard Hughes Medical Institute to support her studies towards a doctoral degree in science. The Gilliam fellowships aim to increase diversity in college and university faculty members.
The zebra finch genome sequencing project reveals insights into the genetics behind brain wiring, learning, and memory. The study also sheds light on evolutionary relationships between bird and mammalian genomes, identifying characteristic features common to both.
Despite being a common medical emergency, half of UK patients needing emergency investigation for sudden gut bleeding still wait too long for endoscopy. This audit reveals significant delays and underuse of standard treatment, affecting thousands of lives annually.
A study of copy number variations in the genome found no significant link between these changes and common diseases. However, rare genetic variants and epigenetic factors are believed to play a role in disease susceptibility. The research suggests that focusing on other genetic variations may lead to important advances in human health.
Researchers discovered that immune suppressive cells in the liver may facilitate cancer spread, and targeting these cells could prevent it. Combating immune suppressive cells early after cancer development may keep the disease from spreading to the liver.
Researchers discovered that bone marrow cells produce nerve growth factor, which promotes angiogenesis and prevents hypoxia in transplanted islets. The study, led by Dr. Eba Hathout, found a potential role for NGF in islet transplantation and prevention of graft failure.
A study by the Mongan Institute at Massachusetts General Hospital found that women conducting research in life sciences receive lower levels of compensation than their male counterparts, even after controlling for professional activities and academic accomplishments. Women also take on more administrative tasks, leading to a pay gap of...
A new study has discovered that the 'vegetable lamb' plant contains substances with promise as treatments for osteoporosis. The plant's compounds blocked the formation of bone-destroying osteoclasts in up to 97% of laboratory cultures without harming other cells.
A new study published in Gastroenterology found biofeedback to be more effective than electrogalvanic stimulation (EGS) and digital massage in relieving chronic rectal pain. Researchers identified patients most likely to improve through physical examination, highlighting the potential for personalized treatment approaches.
Researchers at NIH/National Institute of General Medical Sciences have created a synthetic population using census data to simulate disease spread and study social networks. The virtual population accurately represents the country's demographics, allowing for faster and more accurate disease-spread simulations.
Engineers at Boston University have developed mathematical algorithms that can make nearly optimal decisions under realistic model conditions. This approach automates functions such as task partitioning and re-planning, reducing human supervision needed for UAVs.
A study found that motor actions can determine people's emotional memories, with participants remembering more positive life experiences when moving marbles upward and more negative experiences when moving them downward. This suggests that spatial metaphors for emotion are not just in language but also in mental processes.
The interactive map shows a majority or complete loss of freezing zones in every state analyzed under high carbon pollution scenario. Early snowmelt and altered water cycles threaten irrigation supplies, cold-water stream life, and forest health.
Bacteria have a CRISPR defence system that can be passed down to future generations, providing immunity against viral attacks. This system could be exploited to give bacteria 'flu jabs' to protect them against real-world threats, increasing industrial productivity and reducing costs.
Cyclone Paul has moved back toward the Gulf of Carpentaria, with a cyclone watch in effect for coastal communities. TRMM satellite data shows light to moderate rainfall over land and isolated heavy rain over the Gulf.
A study by OSU researchers found that rural Oregonians use similar rates of public assistance programs as urban areas, except for food stamps. This may be due to differences in eligibility requirements and social network support. The findings highlight the need for policymakers to address access issues in rural areas.
The Lawrence Berkeley National Laboratory will build an Advanced Biofuels Process Development Unit, a first-of-its-kind facility for public use. The facility will accelerate the commercialization of next-generation biofuels by providing industry-scale test beds for innovative technologies.
Scientists at the University of Delaware have developed a new method for producing ubiquitylated proteins, which may hold the key to understanding cancer cell resistance to drugs and other diseases. The new approach combines intein chemistry and disulfide crosslinking to yield hundredsfold more proteins than current methods.
Researchers have found a specific genetic cause of schizophrenia that impairs communication between the brain's decision-making and memory hubs. Engineered mice with this mutation show difficulty with working memory tasks, highlighting the importance of connectivity in learning and memory.
A novel stem cell therapy has been developed to arm the immune system against HIV, potentially improving quality of life and life expectancy for those who have failed antiviral drugs. The therapy involves delivering antiviral DNA to patient immune cells, which can block viral gene production using RNA interference.
Researchers discovered a nearly complete juvenile Diplodocus skull that reveals drastic changes in skull shape during normal growth. The discovery provides new insights into the feeding behavior of young Diplodocus, which may have been choosier browsers selecting high-quality plant parts.
A comprehensive study documents American industry's water usage, revealing that most water is used indirectly in processing such as packaging and shipping food crops. The study estimates water use among over 400 industry sectors, with surprising amounts required for common products like sugar, dog and cat food, and milk.
A study found that song sparrows from California displayed higher body temperatures during the night due to their longer breeding season, allowing them to prioritize their immune response. In contrast, sparrows from Washington had shorter breeding seasons, which may limit their ability to invest in immune reactions.
An international team of scientists has decoded the genome of a songbird, the Australian zebra finch, to understand the genetic basis of vocal learning. The analysis suggests that hundreds of genes are activated by singing or hearing songs, including non-coding RNAs that control gene expression.
The Australian zebra finch's genome reveals a complex system for singing, with over 800 genes regulated by the action of singing. The findings may help scientists understand how humans learn language and identify genetic origins of speech disorders like autism, stroke, and stuttering.
Researchers found that zoledronic acid decreased detectable tumour cells in women with locally advanced breast cancer, particularly after 3 months of treatment. The study suggests zoledronic acid's potential to alter the microenvironment making it less favourable for cancer cells.
Researchers identified over 800 genes involved in male zebra finch song learning and found complex gene regulatory networks in the brain. The study's findings may help diagnose and treat conditions like stuttering and autism.
A new study led by LSU researcher Mandi Lopez aims to improve treatment of broken bones in horses. Adult equine stem cells have shown promise in repairing bone injuries, but little research has been done on the best combinations of stem cells and carriers.
Researchers at Columbia University Medical Center found a genetic variant causing disrupted communication between brain regions, leading to working memory deficits and increasing the risk of schizophrenia. The study used a mouse model with a 22q11 deletion mutation, which showed impaired neural activity and behavior in cognitive tasks.
Research found that spray gun technique and application rate significantly affect the effectiveness of pesticide deposition on ivy pot plants. The study suggests using a disc-core nozzle with high-pressure equipment to improve performance.
Researchers discover how breast cancer cells become resistant to hormone-dependent treatments like tamoxifen by activating a specific biochemical cascade. The study reveals the permanent stimulation of cyclic AMP in cells refractory to therapy, providing key answers to understanding resistance.
A new study challenges existing knowledge about the kinetics of T cell receptors, finding that interactions with potent antigens are short-lived and occur rapidly. The research uses two techniques to analyze receptor-antigen interactions on cell surfaces, revealing a broader dynamic range than previous studies.
Scientists have identified a new approach to tackling human African trypanosomiasis (HAT), also known as sleeping sickness. A valid drug target has been found and leads for orally administered drugs have been identified, showing promise for effective treatment of the disease.
A new study found that ghrelin improved appetite and food intake in gastric cancer patients who had part or all of their stomach removed. Body weight loss was significantly lower in the ghrelin group compared to the placebo group, indicating a potential benefit for these patients.
Research by Daniel Casasanto shows that children link distance and duration in time, but struggle to separate the two. Children use physical distance to estimate the passage of time.
A large-scale study found that patients with GERD and IBS often experience overlapping symptoms, including nausea, bowel movement changes, and extra gastrointestinal issues. This suggests a potential systemic link between the two disorders.
A recent study by John Deering found that newly recruited probation officers in the UK value humanistic approaches to rehabilitation over punitive measures. The respondents emphasized the importance of addressing social and economic inequalities contributing to crime, rather than attributing it to individual failures.
Researchers at the University of Innsbruck successfully created a single-atom laser, demonstrating both classical and quantum mechanical properties. The experiment showed that by tuning the coupling between the atom and cavity mode, stimulated emission could be achieved despite the atom's weak amplification ability.
Researchers analyzed the zebra finch genome, finding large and complex gene regulatory networks in the brain activated by song communication. The study also discovered non-coding RNAs play a crucial role in regulating gene expression.
The Ensembl project has successfully catalogued the genetic diversity of over 50 species, including the zebra finch. The genomic annotation system enabled researchers to identify genes expressed in the zebra finch brain responsible for vocalising messages.
Scott Russell Sanders' essay 'Mind in the Forest' has won the John Burroughs Award for its thought-provoking exploration of human connection with nature. The essay, written during a USDA Forest Service writers' residence, was recognized for its exceptional literary value and ability to reveal qualities of the forest previously invisibl...