Canadian researchers have identified a previously hidden channel in humans that allows anti-cancer agents like Bleomycin to target leukemia cells. This discovery may revolutionize treatment for acute myeloid leukemia, a cancer affecting white blood cells.
Researchers found that adding chymase inhibitors to ACE inhibitors significantly boosted recovery of heart function in animals after a heart attack. This could lead to improved treatments for people with high blood pressure, heart failure, and other conditions.
A large-scale Dutch study finds that bullies aim to gain status by dominating victims, while avoiding social rejection from peers. The study also reveals that gender plays a significant role in bullying behavior.
A study found that children distinguish between moral and personal domain rules, with moral rules associated with compliance and feelings of good emotions, while personal domain rules lead to disobedience and positive emotional experience for the child.
Air and water pollution in China pose significant health risks, with indoor air pollution from solid fuels responsible for millions of premature deaths. The country has made some progress in reducing industrial waste and improving access to piped water, but more efforts are needed to address the issue.
A new study from Rhode Island Hospital has found that a widely-used screening tool for bipolar disorder may incorrectly identify borderline personality disorder. The research team tested the accuracy of the Mood Disorder Questionnaire (MDQ) and found that it misidentified patients with borderline personality disorder, leading to potent...
A study found that up to 42% of people with undiagnosed diabetes and nearly 18% of those with prediabetes have chronic kidney disease. This suggests a significant number of individuals may be at risk for worsening kidney disease, emphasizing the need for earlier screening and timely medical care.
Researchers found that exposure to fast food symbols increases preference for time-saving products, reduces willingness to save, and promotes a general sense of haste. The study highlights the potential impact of fast food on everyday psychology and behavior.
Researchers at EVMS Strelitz Diabetes Center have received a $1.076 million grant from the Department of Defense to develop new treatments for Type 1 diabetes, focusing on regeneration of insulin-producing beta cells and neutralizing the immune system's attack. The goal is to create a functional cure using a combination therapy regimen.
Scientists at NYU Langone Health discovered a potential new target for treating rheumatoid arthritis by boosting the normal activity of regulatory T cells, which counterbalance conventional T cells' hyperactivity. The study reveals how an investigational drug wards off inflammation by holding an enzyme at bay.
A protein called Kibra has been found to regulate organ size by controlling cell growth and death. This discovery may hold the key to understanding and treating cancer.
Researchers at McMaster University have discovered how specific proteins on cell surfaces bind to double-stranded RNA, triggering an immune response. This finding could lead to the development of targeted antiviral therapies with reduced side effects.
Researchers at Boston Children's Hospital discovered a possible way to kill off leukemia stem cells and prevent relapse. The study found that targeting the Wnt/beta-catenin pathway can suppress leukemia recurrence by inhibiting beta-catenin, a crucial player in leukemia stem cell development.
New research reveals that pneumonia, birth asphyxia, and preterm birth complications account for between 15-17% of child deaths in China. The study found a significant decline in mortality rates from 1990-2008, with improvements in neonatal, postneonatal infant, and child mortality rates.
Researchers found that women who have been diagnosed with breast cancer tend to overestimate their risk of developing cancer in the other breast. After counseling and a 12-month delay, most patients reconsidered and opted against prophylactic surgery.
Researchers at EPFL discovered how tumors create a tolerant microenvironment by mimicking key features of lymph nodes. This allows tumors to avoid detection by the immune system, leading to cancer progression.
Researchers develop fluoromodules, dye-protein complexes that provide alternatives to GFP with a wider selection of colors and increased photostability. This technology enables real-time monitoring of biological activities in living cells.
A study found that Mexican Americans are 40% less likely than non-Hispanic whites to call 9-1-1 and be taken to the hospital via ambulance for stroke, leading to delayed medical treatment. Women, particularly those from the Hispanic community, were also more likely to experience delays in receiving timely care.
Researchers have identified a compound in blackcurrants that reduces lung inflammation and complements the body's natural immune response. This discovery could lead to the development of foods containing these compounds as a natural alternative to assist conventional drug treatments for asthma.
Researchers have identified two genes, LRRN3 and LRRTM3, associated with autistic spectrum disorders (ASD), providing valuable insights into the genetic basis of the condition. Variations in these genes were found to be significantly associated with susceptibility to ASD.
Women diagnosed with breast cancer after pregnancy are 48% more likely to die than others, but risk is similar if cancer is diagnosed during pregnancy. Further investigation is needed to understand the relationship between cumulative pregnancy effects and breast cancer prognosis.
A preclinical model of human prostate cancer mimics primary tumors' genetic behavior, offering a platform for biomarker and drug discovery. High expression levels of delta-like ligand 4 in breast cancer predict poor prognosis.
New research suggests that pregnant women with breast cancer can be treated with chemotherapy without endangering the health of their unborn baby. The study found that babies exposed to chemotherapy during pregnancy were born slightly lighter but otherwise had similar outcomes as those not exposed to chemotherapy.
A new enzyme-linked immunosorbent assay can detect Alzheimer's disease by measuring high molecular weight A-Beta oligomers in spinal fluid. The test showed direct correlation between A-Beta oligomer levels and memory impairment, enabling early diagnosis of the disease.
Researchers at McGill University have discovered a modified protein that plays a key role in memory processes, altering its function and enabling stronger neural connections. This finding represents an important step in understanding how the brain stores memories.
A longitudinal study found that teenagers' input into decisions gradually increased from ages 9 to 14, then surged from 15 to 20. Young people had more autonomy in decisions about appearance, activities, schoolwork, and social life than chores, health, and curfew.
Researchers from the University of Extremadura have discovered a new species of Cloudina, a small animal with an external skeleton, in Spain. The fossils show evidence of asexual reproduction, a rare phenomenon previously only described in Chinese specimens.
Scientists have made a significant discovery in corn breeding that could lead to higher crop yields, improved disease resistance and heartier plants able to withstand severe weather. By understanding the genetics of photoperiod response, researchers hope to be able to overcome the barrier to using tropical maize for temperate varieties.
Researchers found that surgical masks were as effective as respirators in preventing hospital staff from acquiring H1N1. The study suggests that a uniform policy of using surgical masks when in close contact with patients can protect healthcare workers from infection.
Scientists at UCSF successfully created a new period of brain plasticity in juvenile mice by transplanting embryonic cells into the visual cortex. This approach may one day be used to repair neural circuits following injury or disease. The findings suggest that inhibitory neurons play a crucial role in regulating this plasticity period.
A new study found that women and patients with dementia and diabetes are most likely to enter the Medicare Part D coverage gap, facing significant out-of-pocket drug expenses. The researchers suggest medication cost-counseling interventions for these clinically vulnerable subpopulations may be warranted.
Researchers found that words significantly impacted 3-month-old infants' cognitive performance in a categorization task. Infants who heard words showed evidence of forming the fish category, while those who heard tones did not.
Tropical storm Omais has doubled in size due to wind shear, weakening from 63 mph to 52 mph. The storm is expected to dissipate over the next day and a half as it encounters cooler, drier air associated with a cold front.
A new study identifies women and patients with diabetes and dementia as most likely to fall into Medicare's 'donut hole', a gap in coverage where beneficiaries face unsubsidized medication costs. Researchers recommend doctor-patient counseling to manage drug regimens and prevent adverse effects on patients' health.
A new study shows that older adults' inability to ignore distracting information contributes to memory decline. Prior knowledge of an impending distraction does not improve working memory performance in this age group.
SNM's Clinical Trials Network has gained a new member, Eli Lilly and Company, which will support the initiative to facilitate the development of therapeutic medicines. The network aims to streamline drug discovery and integrate imaging biomarkers into clinical trials, ultimately leading to personalized diagnostics and therapies.
Francisco Ayala, a renowned evolutionary biologist, has won the 2010 Templeton Prize for his contributions to affirming life's spiritual dimension through scientific research. He promotes mutual respect between science and faith, suggesting they are not mutually exclusive but rather complement each other.
A novel research project combines art and neuroscience to explore the connections between visual perception and the brain. Researchers are discovering that artists have intuitive knowledge of neuroscience concepts, including optical illusions.
Researchers identify 110 million-year-old tyrannosaur hip bone from Australia, challenging the idea that tyrannosaurs only existed in the northern hemisphere. The discovery sheds new light on the group's evolutionary history and raises questions about why they evolved into giant predators like T. rex only in the north.
A British scientific expedition is heading to the Cayman Trough, a rift in the seafloor of the Caribbean that reaches over three miles deep. The team will use robot submarines and remotely-controlled vehicles to study deep-sea vents, which support lush colonies of deep-sea creatures.
Researchers identified CEP17 as a highly significant indicator of response to anthracycline treatment in breast cancer patients. Patients with CEP17 were approximately two-thirds more likely to survive and experience recurrence-free survival compared to those without the biomarker.
Scientists have discovered a more economical way to convert wood and other non-food biomass into ethanol fuel, reducing enzyme costs by up to 90%.
Researchers create artificial leaf-like structures that can harness sunlight and water to produce hydrogen fuel, increasing activity by a factor of ten compared to commercial photo-catalysts. The 'Artificial Inorganic Leaf' (AIL) mimics natural leaves' structural features for improved light harvesting efficiency.
A Rice University researcher has developed a natural extracellular matrix from adipose cells that supports the growth of living cells into tissues. The substance, called Adipogel, has been proven effective for growing liver cells and may be used to repair damaged organs in the future.
Scientists at UCSF have developed a novel cell-based strategy to treat Parkinson's disease by transplanting embryonic neurons into the striatum, improving motor function and balance in rats. The approach may offer a more precise effect than traditional strategies and has implications for other neurodegenerative diseases.
Hong Kong's tobacco control efforts have successfully decreased smoking prevalence from 23% in 1982 to 12% in 2008. The region's strategies, including tax increases and anti-smuggling efforts, have contributed to the success.
The new center will provide timely data on prescriptions to doctors, pharmacies, and regulatory agencies, helping identify best practices in prescription monitoring. The initiative aims to reduce the serious epidemic of drug abuse, taking thousands of lives.
Cyclone Ului brought heavy rain to Queensland, Australia, with TRMM satellite capturing the storm's intense rainfall. The cyclone dumped over 180 mm of rain along its path, with Mackay airport reporting 145 mm in 24 hours.
Researchers at Rutgers University found that mice trained to improve their working memory exhibit improved cognitive abilities and remain sharper as they age. Early training appears to have a lasting impact on the mice's intelligence.
Cyclone Imani has developed a 'tail' of clouds and reached category one status due to strong winds. The storm's movement is expected to lead to its dissipation within two days.
A study has identified two new proteins, MHF1 and MHF2, that are indispensable for the functional integrity of the Fanconi anemia (FA) pathway. The research reveals how these proteins work together to bind to specific DNA structures and prevent or repair DNA interstrand crosslinks, which can lead to cell defects and disease.
Scientists found that milkweed species that grow quickly are more vulnerable to insect damage, while fast-growing plants rely on predators for protection. This study provides valuable insights into plant defense mechanisms and has implications for developing pest-resistant crops.
Recent studies have shed new light on explosive volcanic eruptions in the ocean, a 300-million-year-old forest from the Andes, and innovative methods for dating sedimentary rocks. Researchers have discovered a unique eruption style dubbed 'Poseidic,' characterized by uninterrupted magma ascent, while fossil evidence supports an ecologi...
A new study from Iowa State University found that consuming at least 150 milligrams of flaxseed lignans per day can decrease cholesterol in men by just under 10 percent over three months. However, the effect was not significant for women.
A recent meta-analysis of 14 trials found that pregnancy after breast cancer diagnosis reduces the risk of death by 42%. The study suggests that hormonal changes during pregnancy may have an inhibitory effect on breast cancer cells, and that foetal antigens may also play a role in reducing the risk of recurrence. The findings support t...
A Johns Hopkins study found that community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) colonization rates increased among pediatric ICU patients, with younger children and African-American children more affected. Universal screening upon hospital admission and weekly screenings can help curb the spread of MRSA.
A new study reveals that pollutants from Asia are being transported to the stratosphere during monsoon season, potentially affecting global climate. The research found that black carbon, sulfur dioxide, and other pollutants are lifted into the stratosphere by Asian monsoon circulation patterns.
A study found that sirolimus-based immunosuppression significantly increases survival rates for post-transplant liver cancer patients, while radiofrequency ablation shows promise for very early-stage HCC treatment.
Children with insecure attachments have repeated experiences of caregivers responding inconsistently, leading to behavioral problems like aggression and hostility. The meta-analysis of 69 studies found that early insecure attachment to mothers is associated with later behavioral issues in children, including boys.
New Cornell University research reveals how plants at the bottom of the food chain have evolved mechanisms that influence ecosystem dynamics. Plants have developed three main strategies to increase their biomass, including producing volatile compounds called sesquiterpenes that attract predators, which drive modern ecosystems' structure.