A new study found that women aged 67 and older with normal bone mineral density scores may not need re-screening in 10 years. The researchers calculated estimated times for 10 percent of the women to transition to osteoporosis, finding that it would take about 16 years for this group to develop osteoporosis.
SourceUniversity of North Carolina Health Care·DateOct 17, 2010
Researchers are studying a rare form of Hepatitis E affecting middle-aged and elderly men in the UK. The two-year study will examine liver problems in hospital patients and explore transmission through contact with pigs and products.
SourceThe Peninsula College of Medicine and Dentistry·DateOct 17, 2010
Yale University researchers have found a genetic trigger for depression, identifying the MKP-1 gene as a promising target for new antidepressants. The study found that increased levels of this gene are associated with signaling abnormalities in the brain, which can lead to depression.
SourceYale University·JournalNature Medicine·DateOct 17, 2010
Researchers found a link between low blood pressure at night and an increased risk of glaucoma in patients with migraine. Mobile devices like iPhones can also be used to evaluate ophthalmic images with high consistency, revolutionizing digital eye care.
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Fenretinide shows promise in reducing risk of wet AMD and geographic atrophy growth in dry AMD patients. Long-term diabetics who survived over 50 years with type 1 diabetes appear to be protected against PDR, with protective mechanisms activated early in the disease.
UMMS researchers discovered a common link between familial ALS and sporadic ALS, suggesting that the SOD1 gene plays a role in both forms of the disease. The study found that an oxidized form of the SOD1 protein shared characteristics with the mutant SOD1 protein found in familial ALS.
SourceUMass Chan Medical School·JournalNature Neuroscience·DateOct 17, 2010
Researchers have found approximately 90 pre-Columbian settlements in South Brazil, contradicting traditional assumptions of sparsity in inland areas. The discoveries include fertile soils and round depressions that could be the remains of ancient water reservoirs.
A genetic test predicting early menopause risk could help UK women in their 30s plan families. Researchers identified four genes associated with early menopause and found they combined to have a larger impact on the condition.
SourceThe Peninsula College of Medicine and Dentistry·JournalHuman Molecular Genetics·DateOct 17, 2010
Harvard University neurobiologists have created mice that can detect light using optogenetics, a breakthrough tool for understanding the neural basis of olfaction. The study reveals how the brain processes odors and sheds light on the temporal organization of sensory information.
SourceHarvard University·JournalNature Neuroscience·DateOct 17, 2010
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A study confirms that eight human papillomavirus (HPV) types, including HPV 16, 18, and 45, are responsible for over 90% of all cervical cancer cases worldwide. Current vaccines prevent infection by these high-risk HPV genotypes, but future type-specific screening is recommended to target the most common types.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateOct 17, 2010
Scientists discovered a key difference in how TB bacteria and human cells deliver unwanted proteins to their respective recycling factories. This critical difference may help design drugs to disable the bacterial system while leaving normal human protein recycling centers intact.
SourceDOE/Brookhaven National Laboratory·JournalNature Structural & Molecular Biology·DateOct 17, 2010
Scientists link El Nino Modoki to long-term changes in North Pacific Ocean currents, affecting fish stocks and ocean nutrient distributions. The North Pacific Gyre Oscillation (NPGO) is intensifying due to increasing frequency of El Nino Modoki.
SourceGeorgia Institute of Technology·JournalNature Geoscience·DateOct 17, 2010
A recent study in The Lancet Infectious Diseases identified herpes simplex virus and varicella zoster virus as the most common causes of encephalitis in the UK. However, up to 85% of patients worldwide have an unknown cause, emphasizing the need for further research to improve diagnosis and treatment outcomes.
SourceThe Lancet_DELETED·JournalThe Lancet Infectious Diseases·DateOct 17, 2010
A team of Singaporean scientists has made a major breakthrough by discovering the most important genes in human embryonic stem cells, which are crucial for treating debilitating conditions. The researchers identified a particular gene called PRDM14 that makes it easier to turn adult cells into pluripotent stem cells.
SourceAgency for Science, Technology and Research (A*STAR), Singapore·JournalNature·DateOct 17, 2010
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Researchers studied genetic risk factors for age-related macular degeneration (AMD) and found that patients carrying specific genes were more likely to respond to anti-VEGF therapy. Genetic screening may improve glaucoma care by identifying markers for congenital and primary open angle glaucoma.