A new study has found prenatal cardiac defects in mice with Spinal Muscular Atrophy (SMA), a leading genetic cause of infantile death. The discovery has significant implications for treatment, suggesting that the disease may be multisystemic and requiring therapies beyond just motor neurons.
A new study finds that social rejection triggers a momentary decrease in heart rate, mirroring the brain's response to physical pain. Participants' heart rates slowed in anticipation of and after receiving news about another person's opinion of them, with further drops observed when told they were rejected.
Researchers found that circulating tumor cells (CTCs) can provide real-time information on patient's current disease state through biomarker assessments. The technology has potential for non-invasive detection and analysis of cancer biomarkers.
Researchers have developed a model that simulates how disasters affect critical infrastructure, including bridges, roads, water treatment services, and vital economic components. The model aims to identify vulnerable elements to take proactive measures or find alternatives.
Scientists have created a substance that targets amyloid structures in semen and weakens HIV's ability to infect the body's immune cells. The experimental compound makes it harder for HIV particles to stick to human immune cells, offering a new lead in developing a microbicide to prevent HIV transmission.
Scientists at the University of Leicester are pioneering the use of turmeric extract to target chemo-resistant cancer cells. The research aims to improve chemotherapy effectiveness and prevent disease recurrence.
A study published in the Journal of Evolutionary Biology found that physical attractiveness is linked to evolutionary, social, and economic success. Young, tall, and long-armed women were rated as the most attractive, with narrow waists and a low BMI also contributing to their appeal.
Research published in Annals of Oncology suggests that intrauterine devices releasing progestin hormone levonorgestrel combined with GnRH injections can halt and reverse cancer growth in women aged 40 or younger. The treatment has shown promise in treating specific types of endometrial cancer, preserving fertility for young women.
Researcher Adeela Arshad-Ayaz argues that multicultural education has failed to promote cross-cultural understanding due to inadequate teacher training. She proposes an alternative approach integrating discussion of global politics and social class to create a more equitable society.
A new study by University of Notre Dame ecologist Jennifer Tank and colleagues found that streams throughout the Midwest receive transgenic materials from corn crop byproducts six months after harvest. The research detected Cry1Ab insecticidal protein in 13% of stream sites and dissolved in 23% of water samples.
A genetic inversion in the monkeyflower plant's genome contributes to its adaptation to different environments, leading to reproductive isolation and a shift towards becoming two separate species.
The Goddard team designed a one-of-a-kind structure made of never-before-manufactured composite material that withstood extreme cold temperatures. The structure survived temperatures as low as 27 Kelvin (-411 degrees Fahrenheit), exceeding design requirements.
A meta-analysis of 70 randomized trials found that disease-modifying antirheumatic drugs (DMARDs) and glucocorticoids significantly reduced radiographic joint destruction, similar to biologic agents. Combination therapies also showed promise in reducing structural damage.
A University of Michigan study shows that constructive conflict resolution strategies can lower divorce rates, while destructive behaviors and withdrawal are associated with higher separation rates. Researchers found racial differences in conflict behavior patterns, with Black couples more likely to withdraw during conflicts.
Researchers have developed a new method to analyze neutron reflection to identify buckyballs within polymer-based photovoltaic cells. This breakthrough technique allows for more efficient and cost-effective production of solar cells, which could lead to widespread adoption.
Biologists at Tufts University have discovered that sodium plays a key role in initiating a regenerative response after severe injury, enabling the regeneration of injured spinal cord and muscle. A specific drug-based treatment triggers an influx of sodium ions into injured cells, breaking new ground in biomedicine.
Researchers found that African-American patients with non-small cell lung cancer have similar rates of EGFR mutations, making targeted therapies like erlotinib a viable option. This discovery challenges previous assumptions about racial disparities in lung cancer treatment.
A 59-year-old patient's vertigo and severe hearing loss were alleviated with surgery, restoring her hearing in an extremely rare occurrence. The case highlights the risks of using cotton swabs to clean ears without medical guidance.
Three USU doctoral students receive fellowships to study schistosomiasis, multiple sclerosis and tuberous sclerosis complex. The HJF program aims to develop new drug targets and treatments for these diseases.
Case Western Reserve University researchers develop e-SMART-MH technology to improve patient-provider communications and manage mental health. The project aims to empower young adults to take control of their mental well-being, overcoming stigma and ensuring timely treatment.
Researchers at Monell Center discovered a genetic variation linked to impaired olfactory perception, affecting approximately 14% of individuals. The study used DNA analysis and sensory testing to reveal the connection between an olfactory receptor gene and sulfurous compound sensitivity.
Researchers at Tel Aviv University found dew essential for plant growth in semi-arid zones like the Eastern Mediterranean. Dew provides moisture to plant leaves, enabling photosynthesis and growth during early morning hours.
Experts speculate on future of H1N1 pandemic virus, predicting low mortality rates due to existing immunity in the population. The degree of immunity and potential changes to the virus will impact the upcoming influenza season.
Researchers Prof. Dr. Albert Newen and Christoph Michel propose that self-deception can be a motivating factor in certain situations, while maintaining basic rational evaluation processes intact. However, excessive self-deception can lead to reality distortion and harm.
A new study found that HIV-infected individuals who start antiretroviral therapy (ART) soon after acquiring the virus have stronger immune responses to other pathogens compared to those who start ART later. Early treatment restores resting memory B cells and reduces immature B cells, leading to improved immune system function.
Teens with certain psychiatric diagnoses, such as bipolar disorder and externalizing disorders, are more likely to engage in high-risk sexual behaviors. The study found that those with mania are at an even higher risk for HIV and STIs, having significantly more sexual partners and being four times as likely to have an STI.
A new disposable device based on microfluidics can efficiently capture cancer cells overexpressing HER2, enabling therapy with trastuzumab. The device offers a non-invasive alternative to current methodologies and has shown promising results in early studies.
A section of northwestern Harris County is sinking rapidly due to groundwater withdrawal and subsidence. Researchers analyzed GPS data over a decade, finding that some areas sink up to 5.5 cm/year.
New research from the University of Southern California found that sparkling drinks activate pain sensors in the nasal cavity, similar to mustard and horseradish. The study discovered a specific type of cell responsible for this sensation, known as TRPA1.
Researchers at Van Andel Research Institute have identified synthetic compounds that can mimic the effects of plant hormone abscisic acid, helping plants retain water during drought. These findings could lead to sprays that use a plant's natural defenses to improve drought tolerance and combat global food shortages.
Dr. Eric Deemer's $312,000 NSF grant aims to understand how stereotype threat affects women's motivation in science. The study will inform practical recommendations for pedagogical and career intervention strategies.
A recent study by Penn State researchers found that front-line hotel employees who are envious of their co-workers' relationships with supervisors are less likely to help or volunteer for additional duties. Envy can create a hostile work environment and negatively impact customer satisfaction, the study suggests.
The AAO-HNSF miniseminars discussed presbycusis, a growing concern for older adults with hearing loss. The researchers also presented new medullary thyroid cancer guidelines, highlighting the need for familiarity with unique diagnostic and treatment paradigms. Additionally, safety concerns in pediatric ambulatory surgery were emphasized.
The Mayo Clinic Center for Social Media has launched a global Social Media Health Network, bringing together institutions from around the world to harness the power of social media in healthcare. The network aims to share best practices, develop training resources and facilitate growth of social media programs.
Researchers have found a gene associated with aggressive skin cancer, INPP5A, which could predict its onset and track its progression. The study suggests that targeting this gene may provide new ways to prevent and treat cutaneous squamous cell carcinoma.
A recent study by Professor Sonia Ghumman at the University of Hawaii at Manoa found that Muslim women who wear hijabs face significant workplace discrimination in the US. The survey revealed that 22% of respondents were personally denied work due to their attire, highlighting a pervasive issue of religious intolerance.
Tropical Depression 16 has strengthened due to cold cloud top temperatures, indicating stronger thunderstorms. The storm is expected to bring heavy rains and squally conditions to the Caribbean before moving towards Florida.
Scientists estimate that at least 183 million Americans have immunity to the 2009 pandemic H1N1 virus due to exposure or vaccination. They predict the virus will persist in a form causing relatively few deaths, but caution against complacency and urge influenza vaccination for all ages.
A study published in The Lancet Infectious Diseases suggests that infant immunity to hepatitis B lasts for at least 5 years after primary vaccination, making booster shots unnecessary. The research, led by Alessandro Zanetti, found that children vaccinated with hexavac maintained protective antibody levels for over 5 years.
Researchers detect five types of pharmaceuticals in Donana's waters, including anti-inflammatory drugs and hormones. The study suggests advanced technologies can remove these compounds from urban waste water.
Researchers found that individuals who don't speak English at home are less likely to receive colorectal cancer screenings compared to those who do. The study suggests that patient-provider language barriers and unmeasured differences in patient characteristics contribute to disparities in health care access.
Researchers at the University of Missouri found a positive correlation between investor risk tolerance and stock market returns, indicating investors buy stocks at high prices and sell at low prices. Improved financial education is recommended to help Americans overcome biases in investment decisions.
The study compares and contrasts various global PTSD treatment guidelines, highlighting differences that can lead to confusion. The researchers emphasize the importance of trauma-focused psychological interventions as the most effective treatments for posttraumatic stress disorder.
Researchers from the Institute of Tropical Medicine Antwerp successfully restored a sleeping sickness parasite's susceptibility to drugs, potentially alleviating economic losses. The discovery involves combining antibiotics with an existing medicine, ISM, which could lead to more effective treatments for both cattle and humans.
A novel nanoscale protein measurement technology, NIA, can be used in clinical trials to learn how drugs work and tailor therapy for each patient. The test distinguishes tumor cells from normal cells using protein profiles in the RAS and MAP kinase pathways.
Engineered 'firefly' stem cells can help repair damaged hearts without cutting into patients' chests. Researchers can now track the cells' progress using a special camera lens that picks up the glow under a microscope.
A new species of parasitic wasp, Eurytoma erythrinae, has been released in Hawaii to combat the invasive Erythrina gall wasp, which harms endemic wiliwili trees. The parasite's high success rate has led to significant declines in tree damage.
The PLoS Medicine Editorial argues that drug companies' human rights responsibilities have not been adequately addressed, despite the need to make medicines available to those in need. The editorial highlights the importance of accountability and calls for an external body to monitor pharmaceutical companies' policies and practices.
A new study by USC researchers found that stressed men have diminished brain activity in regions responsible for understanding others' feelings, whereas stressed women show increased coordination. This sex difference is linked to the effects of stress on social behavior and empathy.
A study found that nearly three-quarters of pancreatic cancer tumours have high levels of a protein called P110γ, which could provide a new target for treatments. Blocking this protein stopped cancer cell growth in laboratory experiments.
A new study found that mice subjected to early weaning and maternal separation exhibited long-lasting hyperactivity and anxiety. The researchers hope to use this model to investigate the effects of childhood neglect on human behavior.
University of Michigan scientists have developed a new nanostructuring technology that enables the creation of ultra-small pixels for energy-efficient displays. The technology uses plasmonic structures to trap and transmit light, reducing absorption loss and increasing the efficiency of LED displays.
A Spanish study reveals that combining noise and chemical contaminants can exacerbate hearing loss in workers. While protective masks can filter particles, they have limited effect on toxic gas molecules.
Yang Hong's project aims to increase Pakistan's capacity to reduce natural disaster risks through training, research, and early warning systems. The goal is to strengthen the country's flood risk assessment and management system, supporting vulnerable communities.
A Phase I study has begun to evaluate a combination DNA prime/MVA vector boost vaccine regimen to protect against diverse subtypes of HIV-1. The study will enroll 92 participants and test two intramuscular delivery methods for the DNA prime, Biojector 2000 and CELLECTRA EP, to compare their effects on immune response.
A WCS study found that higher temperatures and rainfall in Argentina result in more parasitic fly larvae, leading to increased mortality and impaired growth for chicks. The researchers also found a positive correlation between climate variables and parasite loads on nestlings.
Researchers have identified a single biomarker that may predict resistance to tivozanib in patients with kidney and breast cancer. The biomarker reflects the presence of white blood cells inside tumors and is associated with clinical activity.
A population-based survey by Pitt's UCSUR found that African American seniors are twice as likely to be mentally abused and five times more susceptible to financial exploitation than elders of other races. The study collected data from face-to-face and telephone interviews with senior citizens in Pennsylvania's Allegheny County.
Individual cancer-causing mutations have a minor effect on tumor growth, increasing cell division rates and contributing to the accumulation of multiple mutations. The research suggests that significant tumor growth requires the slow accumulation of multiple mutations over years, explaining why many cancer-driving mutations are needed.
A randomized trial of chest physiotherapy in infants hospitalized with acute bronchiolitis found no reduction in recovery time. The study suggests that routine chest physiotherapy may not be necessary for this population.