A novel study demonstrates that nanoparticles can retain osteoarthritis drugs in the knee joint, increasing their duration of action. This technology, when used with current or new osteoarthritis drugs, may allow patients to receive injections every three months instead of once a week.
A study published in JAMA suggests that CT scans used for lung cancer screening can help identify chronic obstructive pulmonary disease (COPD) in heavy smokers. The research found that adding an expiratory CT scan to the baseline inspiratory scan improved diagnostic accuracy, particularly for individuals with severe obstruction.
Researchers at Georgia Tech discover that genomic gaps in human and chimp genes are caused by viral-like sequences, leading to differences in gene expression and morphology. The study suggests that 'junk DNA' may hold the key to understanding why humans differ from chimps.
Duke University engineers demonstrated that rigidly constraining dielectric materials can increase their energy density and decrease rates of failure. By preventing physical deformation, epoxy acts as a mechanical constraint to enhance the component's ability to carry greater voltage.
Researchers at Virginia Tech have identified four US strains of the hepatitis E virus in farmed rabbits, closely related to genotype 3, which can spread from animals to humans. The discovery raises concerns about the potential for zoonotic transmission and food safety risks.
Research from Southern Methodist University's Geothermal Laboratory reveals vast geothermal resources across the US capable of producing over 3 million megawatts of green power, outpacing coal plants. The study refines locations for resource exploration using advanced mapping and geological analysis.
Researchers confirm that coyotes migrated eastward via two main routes, one through the northern US and another through the south, before interbreeding with Great Lakes wolves. This hybridization supports the presence of wolf-like coyotes in Virginia, which may help control deer populations.
The NIH study found that etanercept reduces symptom frequency and severity in TNF receptor-associated periodic syndrome (TRAPS) patients. However, long-term treatment effects on preventing amyloidosis are uncertain.
Hurricane Rina is intensifying off Mexico's Yucatan Peninsula, with NASA satellite imagery showing stronger thunderstorms and cloud top temperatures indicating increased power. The storm is projected to make landfall in the hurricane warning area by Wednesday night or early Thursday, bringing heavy rainfall and dangerous storm surge.
The NASA Swift Observatory has released a free iPhone application that provides up-to-date information on gamma-ray burst discoveries, allowing users to track the location of Swift as it orbits Earth. The app also offers an interactive map, gallery of images, and real-time observations.
Researchers have discovered a panel of proteins shed by breast cancer that can distinguish between real cancer and benign lumps. The biomarker panel outperforms mammograms and single biomarkers in distinguishing between breast cancer and benign lumps, with some panels ranking above 0.95.
Researchers discovered that insulin signaling converges with nutrient metabolism pathways to regulate lipid synthesis in the liver. The study suggests that multiple pathways are required for insulin-resistant livers to accumulate lipids.
The region of South Asia experiences a disproportionate burden of neglected tropical diseases, including visceral leishmaniasis, lymphatic filariasis, and soil-transmitted helminth infections. Better management of these diseases is crucial to lessen the region's NTD burden.
Cornell researchers have surpassed two major milestones toward a novel, exceedingly powerful X-ray source: a record-breaking electron gun emittance of 0.8 micrometers and a successfully tested prototype of a superconducting linac cavity.
Researchers discovered that angiotensin-receptor blockers can slow the progression of calcific aortic stenosis, reducing mortality risk and lowering healthcare costs. This breakthrough opens up new avenues for treatment and may potentially delay or prevent valve replacement surgery.
A new study has identified Dpp and Pentagone as key players in the scaling process of a fruit fly's wing. The research found that the feedback loop between Dpp and Pentagone regulates proportional tissue growth, keeping body proportions constant despite external factors like nutrition and temperature.
A new standard definition for loss-to-follow-up (LTFU) has been established for HIV antiretroviral therapy patients, using a 180-day clinic visit threshold. This definition was developed based on statistical analysis of data from 111 health facilities across Africa, Asia, and Latin America.
A study by the Heart and Stroke Foundation found that women under 55 experience worse outcomes after a heart attack, including more recurrences of chest pain and physical limitations. The research highlights the need for increased awareness of risk factors and symptoms among women to improve their health outcomes.
A study by Roman Pfister and colleagues found a potentially causal link between low B-type natriuretic peptide (BNP) hormone levels and the development of type 2 diabetes. The researchers suggest that BNP may be a promising target for interventions aimed at preventing type 2 diabetes.
A University of Michigan survey found most Gen Xers lead active, balanced, and happy lives, with 90% participating in outdoor activities and 40% engaging in two or more recreation and leisure activities per month. Generation X adults are also engaged in community organizations, read regularly, and report high levels of happiness.
Patients with herniated lumbar disc symptoms who waited over six months to undergo treatment had poorer outcomes compared to those who treated their symptoms within six months. Surgical treatment, in particular, was found to be significantly more effective than nonoperative treatment, regardless of symptom duration.
Researchers are developing cutting-edge solutions for renewable energy and environmental research, including thousands of sensors to monitor climate change, novel LED designs that boost efficiency, and thinner solar cells. These innovations aim to make space safer by tracking space debris and improve energy sustainability.
The UCSF Center for AIDS Prevention Studies will receive funding to tackle two primary goals of the National AIDS Strategy: increasing access to care and optimizing health outcomes. The program aims to close gaps in HIV testing, linkage to care, and treatment success among high-risk populations.
A Wayne State University researcher is using a three-year grant to examine the links between stress and drug use in heroin users. The study aims to understand how pharmacologically induced stress affects decisions to seek money or drugs.
A new genomic approach developed by Cornell University scientists enables precise identification of food-borne bacteria, facilitating the detection of outbreaks and their sources. This breakthrough method has the potential to uncover smaller outbreaks that may have gone unnoticed previously.
Breakout Labs aims to accelerate revolutionary science by supporting independent scientists and early-stage companies with radical ideas. Funding is provided through a revolving fund, with successful projects contributing back to the program.
Researchers at 23andMe have identified the potential protective nature of the SGK1 gene against Parkinson's disease, particularly for individuals carrying high-risk LRRK2 mutations. This discovery has the potential to inform therapeutic approaches and diagnostics for Parkinson's disease.
A new study published in Psychological Science found that fans of baseball teams tend to remember the games their teams won more than the ones they lost. The researchers discovered that positive experiences and social factors play a significant role in boosting memory for winning events.
A new genome sequencing method has identified mutations in 12 genes linked to inherited ovarian and related cancers. The test, called BROCA, could become a single test for screening broad range of cancers.
Extensively drug-resistant tuberculosis (XDR-TB) poses a significant threat globally, with over half a million cases of multi-drug resistant TB (MDR-TB) and 25,000 to 50,000 XDR-TB cases. Sanatoria were used to isolate patients, but their dismantling led to the current crisis. The Lancet calls for new-age sanatoria to provide state-of-...
Researchers found that certain strains of Staphylococcus aureus bacteria have genetic variants that enable them to form biofilms on cardiac devices. This discovery offers clues for preventing infections in patients with implanted devices, which currently cost thousands of dollars and millions of dollars in healthcare costs each year.
A new study finds that both dense and non-dense fat tissue are independently associated with an increased risk of breast cancer. The research used sophisticated computer software to analyze mammograms of postmenopausal women with breast cancer, comparing them to controls without cancer.
A multidisciplinary group of researchers found that a glazed stare is accompanied by measurable changes in eye behavior, indicating the existence of a conscious state. This discovery challenges the long-standing debate about the existence of a hypnotic state.
The University of Missouri's Missouri Partnership for Educational Renewal (MPER) has developed a comprehensive approach to suicide prevention in schools. With training efforts, school districts like Parkway School District have implemented standardized responses to address suicidal students before a tragedy occurs.
A study has discovered four gene variants that contribute to early stent thrombosis in people with coronary artery disease. These variants affect blood thinner clopidogrel sensitivity and platelet receptor function, increasing the risk of deadly complications after stent implantation.
Researchers at the University of South Florida have discovered that dormant malaria parasites in red blood cells can recover after antimalarial drug therapy, contributing to treatment failure. The study found a positive association between the number of dormant parasites and when malaria infection re-emerged.
A CCNY team analysis suggests the Greenland ice sheet can experience record-breaking melting even without record-high temperatures due to positive feedback mechanisms. The team's findings indicate a near-record loss of snow and ice, with melting continuing even without last year's record highs.
The University of New Hampshire will provide instruments for the ESA's Solar Orbiter and JAXA's SCOPE missions. The Solar Orbiter will study the Sun's influence on its environment, while the SCOPE mission will investigate magnetosphere processes and solar flares.
Researchers found that cataract surgery improved cognitive ability, mood, and sleep patterns in mild Alzheimer's disease patients. The study suggests that vision correction may boost quality of life for these patients and their families.
Scientists at the University of Calgary discovered Natural Killer T-cells suppress the immune system after a stroke, leading to infections. A new drug has been found to stop these cells from suppressing the immune system, potentially reducing death rates associated with stroke.
Scientists found significant increases in annual temperatures in south-western China, with 77% of weather stations displaying statistically significant rises. Glaciers are retreating at an alarming rate, threatening natural habitats and ecosystems.
A new study reveals that young adults with normal weight and BMI can still have atherosclerosis, highlighting the importance of measuring visceral fat. Waist circumference is a simple predictor of increased visceral adiposity and premature atherosclerosis.
Recent research highlights that faster diagnostic tests are necessary but not sufficient to improve health outcomes for tuberculosis and HIV patients. The study emphasizes the need for thorough evaluation of diagnostics to ensure technical advancements translate into better patient care.
Researchers are examining genetic variations that may predispose Hispanic women to greater breast cancer risk. Additionally, they're assessing the impact of obesity on breast cancer incidence rates among different ethnic groups.
Researchers developed a method to estimate vaccination program effectiveness in three African countries, identifying areas for improvement. The study's findings can inform strategies to increase vaccine coverage and address issues with vaccine delivery.
Researchers discovered that a combination of two gut hormones, PYY and GLP-1, can reduce food intake and appetite by deceiving the brain. This finding has significant implications for obesity therapy and could lead to the development of a daily pill that promotes healthy eating.
A decline of 60% in marten detection rates in California's Sierra Nevada mountains may be attributed to habitat fragmentation and loss due to logging. The study suggests preserving marten habitat, which benefits other species thriving in old forests at high elevations.
Researchers found a significant association between a specific gene variation and accelerated decline in intellectual function with aging. The 'met' version of the BDNF gene was linked to steeper declines in flight simulator scores and smaller hippocampi, a critical brain region for memory and spatial reasoning.
Researchers demonstrate that an anti-caries DNA vaccine, pGJA-P/VAX, combined with a Salmonella protein adjuvant, enhances saliva IgA responses and protects against dental caries. The study shows that the adjuvant promotes specific immunoglobulin A responses in saliva and offers better protection against caries.
The Immunization Action Coalition (IAC) will distribute its publications to healthcare professionals and create new immunization education materials with the support of a $1.4 million cooperative agreement from the CDC. IAC will also become the nation's central clearinghouse for Vaccine Information Statements in languages other than En...
A recent meta-analysis notes that current evidence is not adequate to determine the best margin for common melanoma presentations. A new study adds to the evidence base with no significant difference in overall survival or recurrence-free survival for patients with a melanoma thicker than 2mm and two centimeter resection margins.
A recent study found that conservatives exhibited stronger physiological reactions to disgusting images, particularly those related to gay marriage. The research suggests that people's political orientations are reflected in their biology, with certain attitudes becoming ingrained in the body.
Research by University of Bristol neuroscientists found that cannabis disrupts coordinated brain waves, leading to impaired decision-making and memory. The study suggests that 'disorchestrated brains' may contribute to psychiatric diseases like schizophrenia.
A WSU study suggests chain hotels are more likely to adopt energy-efficient light bulbs, train staff to reduce waste, and educate guests on water conservation. This trend may give independents a competitive disadvantage in attracting customers. Hotels can save up to $6.75 per day by implementing greener practices.
Researchers at the University of Gothenburg have discovered a natural UV filter called scytonemin that can protect against skin damage and allergies. The substance, produced by certain cyanobacteria, absorbs UV light without breaking down, making it a promising alternative to chemical-based sunscreens.
A recent study found that nearly 37% of Alzheimer's patients taking cholinesterase inhibitors also received anticholinergic drugs, which can have negative effects on cognition and function. However, the study revealed no association between dual use and increased risk of death or nursing home entry.
Carbon nanotubes have been used to increase the electrical conductivity of silicon nitride by 13 orders of magnitude, enabling the production of intricate micro-components without compromising production time or integrity. The resulting nanocomposite materials offer improved wear resistance and preservation of mechanical properties.
A comprehensive study of tension wood reveals its unique features and links them to sugar release, which is crucial for producing biofuel. The research provides insight into the molecular and biochemical properties of tension wood, shedding light on how it can be used to design more suitable bioenergy crops.
Exercise and cancer research have received a significant boost with Dr. Kerry Courneya's Canada Research Chair (CRC) renewal. Several large-scale trials are currently underway, including the CARE trial for breast cancer patients and the CHALLENGE trial for colon cancer survivors.
A new international survey reveals that clinicians' awareness and training are key determinants of their approach to addressing patient expectations. Only 16.1% of clinicians reported asking patients about expectations, despite nearly all believing it is important.