A study led by the University of South Florida found that decreasing expression of protein FKBP51 in old mice made them resistant to depressive-like behavior, improving their hormonal response to stress. The lack of this protein did not adversely affect their memory or basic motor functions.
Researchers successfully expanded hematopoietic stem cells a hundredfold by understanding the molecular mechanisms of self-renewal. The study reveals that proliferation, suppression of differentiation and programmed cell death are required for self-renewal.
Marriages between black and white populations have continued to increase, outpacing unions between whites and other ethnic groups. The study reveals that highly educated blacks and whites are more likely to intermarry, indicating a blurring of racial boundaries.
A new study published in the New England Journal of Medicine found that approximately two-thirds of patients with hepatitis C can be cured in six months, rather than the standard 48-week treatment. The study showed that response-guided therapy is a successful strategy for individualizing treatment based on patient responses.
By 2030, urbanized land worldwide will grow by 590,000 square miles, posing threats on environmental and economic levels. Cities tend to have better access to healthcare, water, and sanitation facilities, driving innovation and business opportunities.
NGOs call on UN to address conflicts between public health interests and corporate profits from unhealthy products, contributing to 60% of all NCD deaths. The Conflict of Interest Declaration demands a code of conduct for interacting with the food and beverage industry.
Researchers found that glioblastoma cells need large amounts of cholesterol to grow and survive. Cholesterol-manipulating drugs could potentially lead to significant tumor cell death if this laboratory work is confirmed in larger studies.
Researchers at the University of Missouri have developed a nanotechnology sensor that can detect lung cancer in blood plasma with high sensitivity and selectivity. This technology could provide an earlier warning signal, potentially saving lives. The sensor detects changes in a specific microRNA molecule associated with lung cancer.
Researchers at UCLA found that estrogen treatment can reverse the progression of pulmonary hypertension to heart failure and restore lung and ventricle structure and function. The study suggests that even short-term estrogen therapy may suffice to reverse the disease, offering new potential therapeutic applications for human patients.
Researchers successfully synthesized a large DNA molecule and applied a method to scramble its genetic code, yielding insights into DNA structure and trait expression. The achievement represents a significant step towards synthesizing entire eukaryote genomes.
Researchers found evidence of oceanic crust in ultra-deep diamonds, suggesting it can be transported from the lower to upper mantle via large-scale upwelling. The discovery provides new insights into the Earth's mantle recycling process.
The average installed cost of residential and commercial PV systems fell by 17% and 11%, respectively, between 2009 and 2010. Non-module costs also decreased, with a 18% drop from 2009 to 2010. Large utility-scale PV projects showed even lower costs, ranging from $3.80/W to $4.40/W.
The Gerontological Society of America is releasing two new publications to improve pain relief and medication for seniors. These resources address shortfalls in pain assessment and treatment, as well as labeling changes for acetaminophen, to provide better care and quality of life for older adults.
Researchers at Imperial College London and the University of Oxford used 'optical' laser tweezers and a super-resolution microscope to observe the inner workings of white blood cells, including Natural Killer cells. The study provides new insights into how these cells deliver deadly enzyme-filled granules to kill diseased tissue.
Bertil Fredholm received the 2011 ECNP Neuropsychopharmacology Award for his groundbreaking research on brain adenosine. His work has led to a better understanding of CNS mechanisms in health and disease, with potential applications in treating conditions such as Parkinson's disease, epilepsy, and neuropathic pain.
Researchers at the Paul Scherrer Institute discovered that plants create a water reserve around their roots, which helps them survive short periods of drought. The water reserve is found within a few millimeters from the roots and contains about 30% more water than the rest of the soil.
The study of 17 mouse strains reveals a range of genetic variation, with over 700 biological traits affected by mutations. The findings advance understanding of human disease and evolution, providing a critical resource for researchers.
Researchers discovered that glioblastoma cells depend on large amounts of cholesterol for growth and survival, and that pharmacologically depriving them of cholesterol leads to death. This new strategy may lead to significantly more effective treatments for patients with this lethal form of brain cancer.
The new policy aims to prevent conflicts of interest among companies competing for business with the Office of Naval Research. It covers three categories: impaired objectivity, biased ground rules, and unequal access to non-public information, requiring companies to identify and resolve potential conflicts.
A new study reveals that endothelial cells release cytokines in response to flu infection, rather than virus-infected cells. This finding opens the door for a new type of flu therapy targeting these immune responses.
A team of researchers at Baylor College of Medicine identified a sudden chromosomal catastrophe that occurs early in development, leading to developmental delay and cognitive disorders. The study found that this catastrophe shares similarities with massive genomic rearrangements in cancer.
Researchers at the University of Michigan have developed a new power management approach called E-MiLi, which can reduce energy consumption by up to 44% in real-world wireless networks. The technology works by slowing down the WiFi card's clock and detecting incoming messages using a new firmware modification.
Researchers discovered that genes interact with each other in complex pathways, which can help breast cancer progress. Targeting multiple pathways may lead to more effective combination therapies against the disease. A diuretic used to treat hypertension also showed promise in stopping cancer cell progression.
Researchers have found evidence of the carbon cycle extending to the lower mantle, where it is believed to originate from ocean crust. The discovery was made in 'superdeep' diamonds from Brazil that contain inclusions with chemical compositions indicative of deep-sea environments.
Recent PET-measurements show that mobile phone signals suppress glucose metabolism in specific brain areas. The study, conducted on 13 young males, reveals a methodologically unique approach combining brain imaging, radiation measurements, and modeling.
A new report from the University of Pennsylvania School of Medicine calls for policies to prepare individuals and society for earlier diagnosis of Alzheimer's. Safeguards are needed to protect those at high risk or with a pre-clinical diagnosis, including laws and policies to prevent stigma and discrimination.
Researchers discover that a dwarf galaxy may have created the Milky Way's spiral arms through a collision with our galaxy. Astronomer Curtis Struck cautions that these collisions can have significant effects on galaxy growth and evolution.
The study reveals that methylation changes in humans and chimps have co-evolved over 6 million years, driving changes in DNA sequences and characteristics. This finding challenges the conventional understanding of how methylation affects gene expression.
A new study establishes a link between alcohol metabolism and DNA damage that may be related to breast and liver cancers. Acetaldehyde, a metabolite of alcohol, was found to cause DNA damage and trigger a response in human cells.
Researchers found that memory complaints in older adults are associated with poorer cognitive functioning. The study suggests clinicians should differentiate between types of memory complaints to identify those related to normal aging versus potential cognitive decline.
Researchers found that Wikipedia's cancer information is accurate and comparable in depth to peer-reviewed sites like PDQ, but less readable due to complex language and hyperlinks. In contrast, PDQ is written in simpler English and offers more patient-friendly explanations.
Researchers at Moffitt Cancer Center have identified a molecular pathway that may play a key role in the evolution of chemotherapy resistance in ovarian cancer. The 'BCL2 antagonist of cell death' (BAD) pathway shows promise as a biomarker to identify patients with high-risk ovarian cancer and potentially reverse chemo-resistance.
The 24th ECNP Congress presented landmark studies on the burden of mental disorders in Europe, early intervention in schizophrenia, and sex differences in mental disorders. The event emphasized the need for increased funding and better treatment allocation to address these challenges.
Researchers found that low concentrations of carbon nanoparticles can cause leakage in the cellular lining of the renal nephron, leading to potential harm. The study highlights the need for further research into the effects of CNPs on human health and the environment.
Researchers have discovered that the vaccinia virus construct GLV-1h153 can be used to image and treat pancreatic cancer. The study found that hNIS-mediated radiouptake noninvasively imaged with PET provided information into tumor therapeutic response.
A review of 31 studies found that people born after World War II are more likely to binge drink and develop alcohol use disorders. The gender gap in alcohol problems is narrowing in many countries, highlighting the need for specific public health prevention and intervention efforts.
Research by Dr Jane Pilcher at the University of Leicester found that brands and logos are highly important to some children, shaped by family culture and peer influences. However, Dr Pilcher emphasizes that childhood remains distinct from adolescence, with parents exerting control over their children's consumption.
Researchers are developing a blood test that can identify concussions in athletes by measuring biomarkers such as S100B. The test aims to provide faster and more efficient diagnosis of concussions, which are the leading cause of brain damage in sports.
Researchers identified a specific receptor-based mechanism that triggers cytokine storms, leading to severe lung damage and organ failure. The discovery opens new possibilities for treating this condition with targeted therapies.
A recent study found that people who drink heavily are more likely to die in house fires due to increased risk from smoking and impaired escape ability. The researchers suggest that having someone sober in the home, smoke detectors in bedrooms, or using fire-safe cigarettes could help prevent such deaths.
Researchers studying seaweed-eating fish and coral reef health may develop new methods to manage seaweed growth. The study aims to determine which mix of fish can control the most damaging seaweeds and protect corals.
A new study reveals that warming seas are changing the composition of fish communities in the northeast Atlantic, with southerly species dominating and colder species declining. The analysis of data from over a million fish across 28 years shows a significant increase in warm-water species and a decrease in cold-adapted species.
Researchers found that African Americans experiencing racial discrimination had higher levels of oxidative stress, a potential pathway for cardiovascular and other age-related disease risks. The study suggests that psychological stress from racial discrimination may contribute to racial health disparities.
A team of Iowa State researchers has developed a new method for analyzing drinking water samples in space, using colorimetric solid phase extraction to detect iodine and silver concentrations. The innovative technology will enable astronauts to quickly assess the safety of their drinking water in real-time.
A new study by the University of Bristol reveals that children from disadvantaged backgrounds are more likely to experience abusive partner relationships. The research found that many young people accept violence as normal and struggle to recognize its impact, highlighting the need for education and support to prevent abuse.
The FASEB MARC Program has awarded 19 travel grants totaling $31,350 to promote diversity in biomedical research. The awards support underrepresented minority students and faculty mentors at the 2011 BMES Annual Meeting.
A study found that older women are aware of the risks of sexually transmitted diseases but often avoid discussing them with their physicians due to discomfort. The research highlights a critical need for improved communication between older women and their healthcare providers about sexual health and safe sex practices.
A study published in Neurology has shown that spinal digital subtraction angiography is safe and effective, ruling out misdiagnosis of inflammation and transverse myelitis. The procedure, considered the gold standard for vascular disorders near the spine, was found to have no reported cases of stroke or kidney damage in 302 patients.
Researchers reconstructed the evolutionary history of molluscs using genomics and computational approaches. They found that complex brain formation in mollusks occurred independently at least four times, with surprising outcomes such as cephalopods being an early branch.
The FASEB MARC Program aims to increase the number of underrepresented minorities in biomedical research. For the 2011 EMS Annual Meeting, 1 student received a $1650 travel award.
Researchers at Yale University have successfully converted uterine stem cells into insulin-producing cells, which could lead to the development of a new treatment for Type 1 diabetes. The study found that these stem cells can adopt the characteristics of beta cells in the pancreas and produce insulin in response to glucose.
A new study has shown that a 24-week treatment course for hepatitis C is just as effective as a 48-week regimen for many patients. The study included 540 patients with chronic genotype 1 hepatitis C who had not previously been treated or could not be successfully treated with current standard of care.
A recent study by Carlos J. Torelli and Rohini Ahluwalia found that consumers react positively to brand extensions when products match cultural expectations, but unfavorably when they don't. The authors suggest that understanding a brand's cultural symbolism is crucial for harnessing its potential profitably.
Researchers discovered that evaporated water from trees and lakes helps cool the entire atmosphere, not just locally, through increased cloud formation and reflection of solar radiation. This process has significant implications for land-use decision-making and mitigating global warming.
A new treatment for alveolar rhabdomyosarcoma has been discovered by IDIBELL researchers, using 2-deoxyglucose to inhibit glucose metabolism and cause cell death in tumor cells. The molecule is similar to those used in PET imaging techniques and shows low toxicity at high doses.
Dams and weirs have a profound effect on the ecosystem of watercourses, causing a significant decline in species diversity. The study found that fish species are 25% lower upstream of weirs compared to downstream areas, while invertebrate diversity is up to 50% lower.
A new study found that people salivate in response to material rewards, including money and high-end sports cars. The researchers discovered that this phenomenon occurs when individuals have a strong desire for these items, often driven by a sense of power or goal achievement.
A study of 104 long-term e-cigarette users found that 78% were no longer using tobacco and planned on using their e-cig instead. However, researchers warn about the lack of long-term safety and effectiveness data for these products, as well as poor quality control and regulation.
Researchers mapped the global spread of drug-resistant influenza, revealing that genetic mutations and human migration through air travel can lead to rapid transmission. The study suggests that a combination of factors, including overuse of antiviral drugs and human movement, contribute to the emergence of resistant strains.
Breast and cervical cancer cases are rising globally, with more women dying at younger ages in developing countries. The study reveals stark differences in trends between high- and low-income countries, highlighting the need for increased cancer screening and treatment programs in poor nations.