The new centre will develop better control over crystallisation processes, enabling the production of pharmaceuticals and other products using continuous manufacturing approaches. This could lead to cost savings of up to 60% and energy reductions by up to 70%.
A UC Riverside entomology team proposes a pesticide-free method to increase egg production by targeting a damaging parasite. The strategy involves introducing a natural parasite that competes with and eliminates the more difficult-to-manage fowl mite, reducing egg losses by up to five percent.
A new study reveals that alumina nanoparticles enhance biodiesel combustion, increasing fuel efficiency while decreasing nitrogen oxide and carbon monoxide emissions. Researchers are now exploring other types of nanoparticles for potential engine lubrication and cooling systems.
A study published in the journal Cancer found that synthetic hypericin inhibited the growth of glioma cells and was well-tolerated in patients with recurrent malignant brain tumors. Forty percent of participants completed a three-month treatment regimen without adverse effects.
A study by Indiana University sociologists found that Americans have varying beliefs about college access, with some perceiving minority and low-income students as having more opportunities than middle-class students. Qualified students from low-income families were perceived as having less opportunity than other groups.
Researchers used carbon dating to determine the age of carotid plaques in humans, finding that plaque formation occurs during a relatively short and late time period in life. The study also found an association between low plaque age, higher insulin levels, and instability.
Researchers identify protein TLE3 as a key regulator of fat cell development, which can be targeted to improve adipose tissue function and alleviate symptoms of diabetes. By understanding how fat cells form, scientists aim to develop better treatments for obesity and related disorders.
A recent study published in Gender & Society reveals that scouting manuals steer girls towards arts and crafts while discouraging scientific pursuits. Meanwhile, boys are encouraged to pursue careers like engineering and science. The findings highlight the perpetuation of gender stereotypes in scouting organizations.
A reformed Medicaid program must prioritize coordinated primary care to ensure access and sustainability. The American College of Physicians recommends various improvements, including increased payment rates, reduced administrative burdens, and expanded long-term care options.
Belovsky's study reveals that grasshopper behavior changes with the threat of predators, affecting survival and reproduction. At low densities, reduced feeding increases survival, but at higher densities, it worsens food shortages.
A pilot project aims to improve the accuracy of acute myeloid leukemia (AML) diagnoses in Mexico by standardizing cytogenetic testing. Four Mexican laboratories will participate in the project, which includes a two-year program with oversight from ASH, AMEH, and NCI experts.
A comprehensive survey study confirms the enormous value of science museums in shaping public knowledge and attitudes. The California Science Center was found to be a highly effective institution in inspiring visitors, particularly from diverse backgrounds.
A new gene, SYN1, has been identified as a predisposing factor for both autism and epilepsy in individuals from Quebec. Mutations in this gene lead to impaired synaptic function, causing communication between neurons to break down. This study provides a key to understanding the comorbidity of these devastating diseases.
Researchers at the University of Pennsylvania have made significant progress in controlling the characteristics of lead selenide nanowires, a promising material for semiconductors. By manipulating the exposure to oxygen and chemical hydrazine, they can alter the conductive properties between p-type and n-type devices.
A new point-of-care clinical trial approach is being tested, combining statistical validity with real-world applicability to compare treatments. The approach aims to deliver the best care to patients while learning from each experience, reducing costs and time involved in traditional clinical trials.
A newly merged black hole can be detected by observing the tidal disruption of surrounding stars, which will provide accurate distances and precise sky coordinates. This could lead to a better understanding of dark energy and Einstein's general theory of relativity.
Researchers at the University of Washington have developed two free software solutions to make computer mice easier for people with motor disabilities. The Pointing Magnifier combines area cursor visual and motor magnification, allowing users to acquire targets faster. In contrast, the Angle Mouse adjusts movement angles to make target...
A study by Indiana University found that primary and state-secular schools in Israel adopted environmental education changes more likely than secondary and religious schools. Community-based grassroots efforts played a key role in this adoption.
Researchers identified CRSBP-1 ligand molecules that bind to receptors on lymphatic vessels, gaining entry and facilitating cancer cell spread. This mechanism can be targeted to prevent metastases and treat edema, strengthening immune responses.
Researchers at UBC discovered that real-time fMRI feedback significantly enhances people's ability to control their thoughts. By monitoring the brain region responsible for higher-order thoughts, participants could effectively train their brains and improve mental focus.
A study found that late cancer diagnosis is a major factor in hospital cancer deaths in Northern Ireland, where over half of patients prefer to die at home. The study highlights the importance of early recognition of cancer symptoms and improving community services to support patients' wishes.
Neurosurgeons from NYU Langone present cutting-edge surgical approaches and applications of technology for lateral skull base conditions, low-grade glioma tumors, and spinal surgery. The department's expertise has been recognized as one of the top ten hospitals in the country for neurology and neurosurgery.
A new study found that taking bosentan did not improve health outcomes for patients with idiopathic pulmonary fibrosis (IPF). Researchers suggest a subset of IPF patients may still benefit from the drug, but further studies are needed to confirm this.
Experts gather to discuss the state of knowledge about the New Madrid Seismic Zone, a region prone to large earthquakes with significant economic losses. Researchers also explore computer simulations of earthquake ground motion in the zone, aiming to understand and anticipate future events.
The American College of Gastroenterology published a new evidence-based systematic review on the management of Inflammatory Bowel Disease (IBD), grading treatment options for Crohn's disease and ulcerative colitis. A comprehensive meta-analysis highlights the importance of diet, gut microbiome, and immune system in IBD causes.
A University of Iowa study finds that patients treated with antidepressants after a stroke have significantly greater improvement in physical recovery than those on placebo. The study demonstrates that this effect continues to improve for at least nine months after the medication is stopped.
The VA has seen significant improvements in healthcare quality over the last decade, with better care for seniors and patients with diabetes. However, racial disparities persist, with black veterans experiencing lower quality of care and fewer favorable outcomes compared to white veterans.
A study found that cosmic radiation accelerates atherosclerosis development in mice, worsening existing lesions. This discovery could inform treatment and prevention strategies for long-duration space missions.
Researchers have identified a macrocyclic lactone compound that female emerald ash borers release while feeding, attracting male borers. This discovery has the potential to improve traps for monitoring and controlling the tree-killing beetle.
A three-year follow-up study of patients with chronic hepatitis C who received long-term peginterferon therapy found increased mortality rates attributed to non-liver related causes, primarily in patients with bridging fibrosis. The excess mortality was mainly linked to unrelated complications and did not emerge until three years into ...
Researchers found that welders had an average 11.7 percent reduction in dopamine markers in the brain compared to non-welders, suggesting potential neurotoxic effects from manganese exposure. The study also revealed brain changes consistent with manganese deposits, highlighting a potential public health concern for U.S. workers.
Astronomers have updated the census of sun-like stars with data from NASA's Kepler Mission, detecting changes in brightness in 500 stars. This provides a much better understanding of the stars' properties and their evolution, allowing for detailed measurements of star basics such as mass and age.
Researcher Theresa Pape is developing therapies to jump-start the lives of patients with traumatic brain injury, often falling through the cracks of the medical system. Her innovative clinical trials test the effectiveness of familiar voice intervention and transcranial magnetic stimulation in awakening patients.
Melissa J. Moore, a professor at UMass Medical School, has been awarded the ASBMB's 2011 William C. Rose Award for her groundbreaking research on pre-mRNA processing and mRNA metabolism. She is also recognized for her exceptional mentorship and leadership skills.
Researchers at Albert Einstein College of Medicine have identified two molecules that help cancer cells spread inside the body. The study found that these molecules regulate RhoC activity, which is positively correlated with increased invasion and motility of tumor cells.
The Endocrine Society released a new Clinical Practice Guideline for the evaluation and treatment of pituitary incidentalomas. The guideline recommends a complete history and physical examination, including visual field examinations if necessary, for patients with a pituitary incidentaloma.
Axel T. Brunger, a Stanford University professor, has been awarded the inaugural DeLano Award for Computational Biosciences for his work on structural biology and crystallographic refinement methods. The award recognizes his contributions to making computer technology accessible to the scientific community.
The Society for Experimental Biology and Medicine has recognized seven outstanding young investigators with the 2011 Young Investigator Award. These researchers demonstrated originality, importance, and presentation of their data in various fields of study, including vascular dysfunction and skeletal muscle microvascular rarefaction.
Researchers unveiled groundbreaking cellular analysis tools, drug-delivery methods, and novel approaches to high-throughput drug discovery. The session highlighted advances in imaging and simultaneous identification of biological compounds, as well as the use of peptides as potential drugs and biological probes.
University of Miami scientists studied fossil records of coral communities from nine Caribbean countries to understand reef ecosystems during the Pliocene epoch. They found that free-living corals, well-suited to warm seas, experienced abrupt extinction as seawater cooled and nutrient levels decreased.
A study of 31 patients found that 77% stopped taking anti-tremor medications within a year after DBS surgery, with symptom improvement rates varying among patients. Long-term effects and potential need for continued medication are areas of future research focus.
Job Dekker, an associate professor at UMass Medical School, has been awarded the Young Investigator Award by the American Society for Biochemistry and Molecular Biology. He developed methods to analyze millions of chromosome interactions in parallel, opening a new field of study.
A new supercomputer simulation reveals that the collision of two neutron stars can naturally produce the magnetic structures thought to power short gamma-ray bursts. The study provides the most detailed glimpse of the forces driving some of the universe's most energetic explosions.
Dozens of D.C.-area junior high science teachers will partner with college faculty to develop hands-on activities in biochemistry and molecular biology. The partnership aims to encourage students to pursue high-tech studies and careers, starting earlier in their education.
The American Thyroid Association has released new practice recommendations for outpatient radioiodine treatment, emphasizing travel precautions, personal hygiene, and pregnancy safety. The guidelines comply with US Nuclear Regulatory Commission regulations and provide simplified instructions for care providers and patients.
Researchers have developed a new method to generate induced pluripotent stem cells (iPSCs) using microRNAs, increasing efficiency by 100-fold compared to traditional methods. This breakthrough has the potential to revolutionize regenerative medicine and tissue engineering.
A growing proportion of young people are using hookah water pipes despite misconceptions about its safety. Family habits, such as father or sibling smoking, significantly increase the likelihood of hookah use.
Cities worldwide are failing to protect residents from climate change impacts, despite billions of people being vulnerable to heat waves, sea level rise, and other changes. Fast-growing urban areas are particularly at risk, with many cities lacking effective strategies to safeguard their residents.
Research suggests that treatment for depression may have long-term benefits, with depressed adults who use antidepressants being three times less likely to be depressed eight years later. Cognitive behavioral therapy has also been shown to be effective in reducing symptoms of depression.
Gutierrez-Hartmann's efforts to encourage underrepresented minorities and mentor students have been recognized with the award. The ASBMB established the award to honor scientists who promote diversity in science.
A new study has found that a procedure used in preconception diagnosis to analyze mutant mitochondrial DNA in supporting cells may not accurately predict egg safety for pregnancy. The research highlights the limitations of using polar bodies as a proxy for eggs prior to in vitro fertilization.
Researchers at Scripps Research Institute found that an E. coli enzyme must move to function properly, and blocking these movements renders it defective. The study may lead to the development of more specific and effective drugs targeting enzymes.
A new process developed by Stanford researchers allows people to make IVF embryo donation decisions in private, reducing conflicts of interest. The study found that donors were equally likely to give consent for embryonic stem cell research or human development studies.
A review article in the Journal of Caffeine Research suggests that caffeine disrupts glucose metabolism, increasing insulin resistance and exacerbating blood glucose levels in people with diabetes. The study reveals potential harm of caffeine consumption for over 220 million individuals worldwide affected by type 2 diabetes.
A preclinical study found VitaKine PCT to significantly enhance cardiac function, increasing ejection fraction by 23%, compared to controls. The therapy contains white blood cells in specific ratios and concentrations, offering a precise approach to treating heart attack patients.
Men who are abused by their female partners can experience damaging psychological effects, such as post-traumatic stress disorder and depression. Research found that male victims are at a greater risk of developing PTSD if they have sought professional help after experiencing intimate terrorism.
Researchers at Northwestern University have developed a model that simulates how rats use their whiskers to sense objects around them. The model enables further research on the human sense of touch and may provide insights into new technologies that could utilize the whisker system.
A modified chemotherapy regimen combining reduced CHOP doses with rituximab has shown substantial response and improved survival in very elderly patients with diffuse large B-cell lymphoma. The R-miniCHOP regimen is well-tolerated, with a high overall response rate and low treatment toxicity.
Researchers at Oregon Health & Science University discovered a new approach to prevent ovarian cancer in high-risk women while maintaining fertility. The treatment involves removing the ovarian surface epithelium layer, which has no known function, without affecting ovary function or overall animal health.
A Johns Hopkins patient safety expert argues that current 'metrics' in healthcare are unreliable and hinder quality improvement efforts. He calls for the creation of standardized outcome measures to improve patient outcomes and transparency in data collection.