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Science News for August 25, 2011


Yale researchers use genetic code to engineer a living protein

Researchers at Yale University have successfully re-engineered the genetic code of bacteria to synthesize special forms of proteins that can mimic natural or disease states. This new technology enables the production of human proteins with their naturally occurring phosphorylation sites, a crucial step in understanding disease processes.

SourceYale University·JournalScience·DateAug 25, 2011

New sensors streamline detection of estrogenic compounds

Researchers have engineered new sensors that can detect estrogenic compounds in human cells, which is crucial for understanding the potential health risks associated with these substances. The sensors, developed by a team led by Huimin Zhao, were found to reliably detect estrogenic compounds within hours, even at low levels.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalBiotechnology and Bioengineering·DateAug 25, 2011

4 decades of the rising obesity epidemic

The global obesity epidemic has grown over four decades, with high-income countries experiencing a rise in the 1970s and 80s. Low-income and middle-income countries are now also affected, particularly women from wealthy urban environments. The authors argue that policy-led solutions, such as government regulations and healthy public se...

SourceThe Lancet_DELETED·JournalThe Lancet·DateAug 25, 2011

Making tomorrow's bioenergy yeasts strong

USDA scientists have developed a new biorefinery yeast that can ferment plant sugars into cellulosic ethanol despite the presence of toxic compounds. The yeast, Saccharomyces cerevisiae strain NRRL Y-50049, has shown remarkable tolerance to furfural and HMF, two compounds that inhibit yeast growth and reduce ethanol yields.

SourceUnited States Department of Agriculture - Research, Education and Economics·JournalApplied Microbiology and Biotechnology·DateAug 25, 2011

Workplace stress a growing health hazard

A study by Concordia University economists found that workers in high-stress jobs visit doctors more often, with a 26% increase in healthcare utilization. The study also estimated that workplace stress costs US companies $68 billion annually and reduces productivity by 10%.

SourceConcordia University·JournalBMC Public Health·DateAug 25, 2011

Could a tumor suppressor also fight obesity?

Scientists at Thomas Jefferson University found that silencing the hormone receptor GCC affects appetite in mice, inducing obesity, while mice expressing the receptor know when to stop eating. This new neural-gut axis provides a potential therapeutic target for controlling appetite and obesity.

SourceThomas Jefferson University·JournalJournal of Clinical Investigation·DateAug 25, 2011

A planet made of diamond

Astronomers have detected a planet orbiting a rapidly spinning pulsar, dubbed PSR J1719-1438. The discovery suggests that the planet is composed primarily of carbon and oxygen, likely forming a diamond-like material due to its high density.

SourceUniversity of Manchester·JournalScience·DateAug 25, 2011

A more realistic and accurate weight loss predictive model: 100 calories fewer per day would see weight loss of around 10 pounds over 3 years

A new web-based bodyweight simulation model simulates physiological differences between people based on sex, age, height, and weight. It provides a rough dieting rule for typical overweight adults: every 10 calories per day reduction in energy intake results in about 1 pound of weight loss over 3 years.

SourceThe Lancet_DELETED·JournalThe Lancet·DateAug 25, 2011

Slim down by targeting the hormone uroguanylin

Researchers have identified a potential new target for treating obesity by studying the molecular control of appetite in mice. Nutrient intake triggers the secretion of uroguanylin, which is then converted to uroguanylin and binds to GUCY2C receptors, leading to decreased food intake.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 25, 2011

Results of medication studies in top medical journals may be misleading to readers

A study analyzing medication trials published in high-impact general medicine journals found that surrogate outcomes, composite outcomes, and disease-specific mortality are used, which can be misleading. These outcome measures may not accurately reflect a medication's impact on important clinical outcomes like heart attacks or strokes.

SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of General Internal Medicine·DateAug 25, 2011

LSUHSC research identifies differences in metabolic disease markers in healthy & obese 7-to-9-year-olds

A recent study by LSUHSC research team identified significant differences in metabolic markers between healthy and obese 7-to-9-year-old children. The findings suggest that obesity in this age group may disrupt normal metabolism, impairing glucose tolerance and increasing the risk for Type 2 diabetes later in life.

Researchers developing new test to measure risk for birth defects and neuro-developmental disorders

Researchers at SUNY Downstate have developed a diagnostic test to measure the risk of folate receptor autoantibodies, associated with neural tube defects, autism spectrum disorders, and other neurodevelopmental diseases. The test aims to identify women and children at risk for these conditions, potentially preventing neural tube defect...

Scientists create natural Alzheimer's-fighting compound in lab

Researchers at Yale University have developed a practical method to synthesize huperzine A, a natural enzyme inhibitor that has been used to treat Alzheimer's disease in China. The compound shows promise in combating the effects of chemical warfare agents and may offer improved therapeutic benefits compared to existing treatments.

SourceYale University·JournalChemical Science·DateAug 25, 2011

Cell receptor could allow measles virus to target tumors

Researchers discovered that measles virus can target tumors through the PVRL4 receptor, a marker found on lung, breast, colon, and ovarian cancer cells. This approach could be used to fight various types of cancer, with ongoing experiments testing its effectiveness in mouse tumor models.

SourcePLOS·JournalPLOS Pathogens·DateAug 25, 2011

Exotic galaxy reveals tantalizing tale

Astronomers have discovered a unique spiral galaxy with massive jets, providing insights into the formation of galaxies and clusters in the early universe. The galaxy, dubbed Speca, has been found to exhibit three distinct episodes of jet activity, shedding new light on the processes that shaped these ancient structures.

SourceNational Radio Astronomy Observatory·JournalMonthly Notices of the Royal Astronomical Society·DateAug 25, 2011

Government-led efforts targeting eating habits of children needed to curb worldwide obesity epidemic

A new paper calls for coordinated global effort to monitor and prevent childhood obesity, citing taxes on sugary drinks and marketing restrictions as effective cost-saving strategies. International organizations must work with governments and private sector to promote healthy eating habits and physical activity among children.

Life expectancy success story

Researchers found that life expectancy in deprived areas of Brazil increased at three times the rate of more affluent areas, narrowing the gap to 4.2 years by 2005. This decline in social inequalities in life expectancy corresponds to a significant increase in life expectancy between deprived and affluent areas.

SourceBMC (BioMed Central)·JournalInternational Journal for Equity in Health·DateAug 25, 2011

Getting back from a trip 'ahead of time'

A new study by Niels van de Ven and colleagues found that people tend to overestimate the length of their outward journey, making the return journey feel shorter. The researchers believe this is due to prior expectations rather than familiarity with the route.

SourceSpringer·JournalPsychonomic Bulletin & Review·DateAug 25, 2011

Identifying correlations in electronic patient records

Researchers used text mining to analyze electronic health records and identified co-occurrence of diseases and clustered patients into groups with similar clinical features. The study also mapped disease correlations to the genetic level, potentially revealing a genetic cause behind some diseases.

SourcePLOS·JournalPLOS Computational Biology·DateAug 25, 2011

School-based mental health screening for teens results in connection to care

A new study found that school-based mental health screening for teens can effectively identify adolescents at risk and connect them with follow-up care. The screening, provided by TeenScreen, identified nearly three-quarters of high school students at risk who weren't receiving treatment.

SourceTeenScreen National Center for Mental Health Checkups at Columbia University·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateAug 25, 2011