A study of women who experienced undernutrition during the Dutch famine found that it was associated with an increased risk of coronary heart disease later in life. The research suggests that childhood and adolescent undernutrition can have a lasting impact on future health.
Researchers have created a method for silencing non-protein-coding genes using zinc finger nucleases. This allows for the study of these genes' molecular and cellular functions, which are thought to play a role in cancer development.
Researchers discovered the expression of cancer-killer SAC-GFP activity in bone marrow cells after transplantation, suggesting successful transfer and colonization of anti-cancer tissue. The study shows promise for treating primary and metastatic tumors with genetically modified stem cells that secrete potent Par-4/SAC killer proteins.
The MacArthur Foundation Research Network on Law and Neuroscience, led by Vanderbilt professor Owen Jones, aims to make neuroscience accessible in America's courtrooms. The network explores effects of modern neuroscience on criminal law, including assessing mental states, capacity, and evidence.
A recent study has traced the source of the current cholera pandemic to an ancestor that first appeared in the Bay of Bengal 40 years ago. The analysis reveals that the bacterium's genetic region SXT acquired around 1982, triggering global transmission from this original source.
A new study by Ben-Gurion University researchers found no statistical difference between CSR and non-CSR companies in terms of stock performance. Investors may be more likely to choose CSR-compliant companies despite similar financial returns.
Two studies reveal that the star was torn apart by intense tides as it approached the black hole, creating an unprecedented outburst of energy. The outburst produced X-rays and radio emissions that pointed straight at Earth, offering insights into relativistic beaming.
A researcher has found that individuals with Down syndrome have substantially altered key eye reflexes, leading to poor balance and motor coordination. The study's findings could lead to new tools for assessing the effectiveness of treatments aimed at improving quality of life.
Studies show that ankle brachial index can help identify individuals at high risk of cardiovascular events, while bifurcated prostheses on aorto-iliac lesions may improve PAD treatment outcomes. Early detection and intervention are crucial to managing PAD and preventing serious consequences.
A national database called WATERiD will provide accurate predictions of when underground water and wastewater pipes might fail. The database, launched on Sept. 1, aims to create a single point for utilities to access relevant information and accelerate decision-making.
A four-year study found that exercise can be as effective as a second antidepressant medication for half of depressed patients, with moderate exercise more effective for women with a family history of mental illness. The type and intensity of exercise needed depend on patient characteristics, such as gender.
Repeated cocaine use increases depressive-like responses in a mouse model of depression, linking substance abuse with increased stress-related illnesses. Histone modifications play a key role in this process, suggesting potential therapeutic targets for mood disorders associated with substance abuse.
A statistical analysis by Curt Nichols predicts Obama will land at the 22nd spot on expert ranking lists if he serves only one term. He is likely to receive credits for his four years of service and wartime leadership, but may be penalized for failing to lift the nation out of crisis.
A new approach enables precise mass measurements of single molecules using molecular oscillators, overcoming limitations of conventional mass spectrometry. The technique allows for fast, miniaturized, and real-time analysis of molecular binding affinity, paving the way for versatile low-cost mass spectrometry measurements.
Hurricane Irene strengthened into a major hurricane on the GOES-13 satellite video, reaching Category 3 status with 115mph winds. The storm is expected to make landfall in eastern North Carolina as a major hurricane, bringing devastating damage and heavy rainfall.
Women's sexual satisfaction is linked to their overall quality of life and perception of successful aging, even as physical health declines with age. Approximately 67% of women reported being moderately to very satisfied with their sex lives across different age groups.
A new Commonwealth Fund report reveals that nearly three-quarters of people who lost their health insurance when they lost their jobs over the last two years skipped needed health care or struggled with medical bills. The Affordable Care Act will provide expanded health insurance options, including subsidies and Medicaid coverage, star...
A recent UCSF study analyzes the long-term effects of chemotherapy on women's reproductive health, finding that younger women are more likely to experience early menopause and infertility. The research provides new insights for patients and clinicians, enabling more strategic and personalized counseling about fertility preservation.
New research reveals that human beings can visually detect living presence through specific movement cues, including those close to the ground and mimicking real gravitational acceleration. The visual system is keyed into these cues to determine a moving object's life-detection.
Researchers found that a genetic switch in master neurons inhibits the proper functioning of protective cell stress responses, accumulating misfolded and damaged proteins. Restoring this natural ability could offer a new target for therapy, improving cellular health and quality of life.
Researchers have identified a protein used by Ebola virus to gain entry into cells and begin replicating, providing a new target for antiviral drugs. This discovery may lead to the development of more stable and effective treatments for Ebola hemorrhagic fever (EHF), currently caused by one of the deadliest known viruses affecting humans.
Researchers found that adventurous females prefer mates with similar outgoing personalities, regardless of physical attributes. This study provides evidence that compatible personalities play a crucial role in partner choice in non-human species.
Scientists at Albert Einstein College of Medicine have discovered a key cellular protein, Niemann-Pick C1, that is essential for the Ebola virus to infect cells. The finding suggests a possible strategy for blocking infection due to Ebola virus, which has killed up to 90% of those infected in some outbreaks.
Researchers at Brigham and Women's Hospital identified a novel small molecule that inhibits Ebola virus entry into cells by more than 99 percent. The target of the inhibitor is the cell protein Niemann-Pick C1, which is critical for EboV infection.
Researchers studying HIV in Pakistan's general population found the virus has spread beyond at-risk groups to women and children. Genetic analysis suggests the strongest factor of disease spread is through men who sleep with male intravenous drug users.
A study using advanced brain imaging techniques found that 33% of participants had high levels of amyloid-beta deposits, indicating an increased risk of Alzheimer's disease. The study also discovered a link between these deposits and changes in brain metabolites, which may help identify people at risk for the condition.
A George Mason University research team has uncovered a new factor, LIMK, that triggers cell movement essential for HIV infection. The discovery builds upon previous findings and provides a potential therapeutic target to limit or halt HIV infection.
Researcher Martin Blaser warns that widespread antibiotic use can cause permanent damage to the body's natural defense system. This can lead to increased susceptibility to infections and disease, as well as conditions like asthma, inflammatory bowel disease, and type 1 diabetes.
A study found that El Niño boosts temperatures and cuts rainfall, doubling the risk of civil wars in affected tropical countries. The research tracked ENSO from 1950 to 2004 and correlated it with onsets of conflicts, finding that El Niño may have played a role in 21% of civil wars worldwide.
A team of researchers has reconstructed and tested a trafficking pathway for hundreds of cell proteins, finding that they can be delivered to the membrane via a simple three-part system. This discovery could have significance for the development of new drugs and bioengineering methods.
Researchers study paleo-hurricane records from South Carolina marshlands and find that spatio-lateral continuity of hurricane deposits is poor. High-precision geochronology of the Chinle Formation provides new insights into early dinosaur evolution and temporal constraints on their evolution.
A new study by the National Institutes of Health (NIH) has found that adding azithromycin to daily treatment regimens for chronic obstructive pulmonary disease (COPD) can lower frequency and severity of flare-ups. The medication was shown to improve breathing ability and overall well-being in patients with COPD.
New research finds that hippocampal neurons encode every sequential moment in a series of events, bridging gaps between discontiguous events. The activity of these 'time cells' signals the timing of key events and can differentiate between different types of sequences.
The photonics center will develop novel sensing technologies for remote oil storage measurement, gasifier refractory wall monitoring, and on-line dissolved gas detection in transformers. This will improve the efficient operation of advanced power systems and reduce costs associated with transformer failures.
The FASEB MARC Program announces the selection of six recipients, who will receive a $3,000 unrestricted career development award and a travel stipend to support their participation in national scientific meetings. The awards aim to increase competitiveness among underrepresented minorities in biomedical research.
The discovery of Juramaia sinensis, a 160-million-year-old fossil, fills an important gap in the fossil record and helps to calibrate modern DNA-based methods of dating. The fossil provides evidence of the date when eutherian mammals diverged from other mammals.
Researchers identified Niemann-Pick C1 as a critical cellular protein for Ebola virus entry, allowing scientists to develop antiviral drugs. The discovery offers a promising strategy to combat the deadly virus.
Researchers claim most crowd estimations are unreliable due to political bias and have devised new methods for estimating static and mobile crowds with reduced margin of error. The 'area x density' method for static crowds and the 'two-inspection-point' method for mobile crowds can provide more accurate estimates
Researchers at the University of Hawaii Cancer Center and The Queen's Medical Center will analyze gene expression and imaging data to detect liver cancer earlier. They aim to improve patient outcomes and reduce deaths from this deadly disease.
Researchers have successfully controlled Dengue fever in northern Australia by releasing Wolbachia-infected mosquitoes, which suppress the virus and prevent transmission. The study demonstrates a promising approach to eliminating this disease, with potential applications in other regions.
The FDA has cleared a new diagnostic test that detects the cryptoccocal antigen, allowing for early diagnosis and treatment of cryptococcosis. The rapid blood test, known as the CrAg Lateral Flow Assay, is designed for resource-limited settings and can be administered in just a few minutes.
People with declarative memory impairment have trouble making common ground in conversation due to their inability to form new declarative memories. In the study, participants with amnesia looked equally at two elephants, showing no benefit from earlier conversations.
A common bacterium, Wolbachia, has been found to prevent the Aedes aegypti mosquito from transmitting the dengue virus, a major public health threat. The discovery offers a promising alternative to current control methods and could have a transformative effect on global health.
The discovery reveals changes in silicon's mechanical response with decreasing size, driving unexpected deformation mechanisms. This finding provides a basis for understanding the onset of plasticity in nanovolumes, benefiting nano-device design.
A study by UC Davis researchers found biological indicators of toxic fat cells in those with metabolic syndrome, which may lead to diabetes and cardiovascular disease. The discovery supports a new high-risk obesity category for these conditions.
Researchers have created a detailed map of gene expression in the mouse cerebral cortex, which shares 90% of its genes with humans. The atlas provides insight into how genes work in this complex region of the brain, including correlations between specific genes and human diseases such as Parkinson's and Alzheimer's.
Researchers have discovered that human amniotic fluid-derived stem cells (hAECs) can differentiate into various cell types, including those found in the lungs. Transplanted hAECs were shown to reduce pulmonary fibrosis and enhance lung regeneration in animal models of lung disease.
Researchers at Scripps Research Institute successfully designed a new antibiotic that can target and kill the most resistant bacterial infections. The compound, an analogue of vancomycin, overcomes the resistance mechanism by altering the key atom in the peptidoglycan structure.
Researchers identify Niemann-Pick C1 as critical protein for Ebola virus entry, paving the way for potential antiviral treatments. The discovery improves chances of developing drugs that directly combat Ebola infections.
Researchers found that trial-and-error learning benefits older brains more than errorless learning in certain conceptual tasks. Older adults outperformed younger peers in memory tests when learning through trial-and-error., This challenges the long-held assumption that making mistakes hurts memory performance for older adults.