Researchers developed a practical and general method to synthesize organoboron compounds for Suzuki reactions, improving yields and reducing waste. The new approach enables the creation of diverse organic molecules, including novel drugs and materials.
A new study of Swedish lakes suggests that power station emissions may have played a smaller role in acidifying the lakes than previously assessed. Organic carbon from living organisms has been found to be a significant contributor to lake acidity, and pre-industrial levels were likely even higher.
A recent study confirms that long-term azithromycin treatment is associated with increased infection with nontuberculous mycobacteria, a serious complication in cystic fibrosis patients. The team identified autophagy impairment as the underlying mechanism, highlighting a clinical danger of pharmacological blockade.
Researchers discovered Robert Burns Woodward's notes on organic superconductors, including original scans of his work, and successfully redrawn compounds using modern techniques. The study sheds light on Woodward's ideas for developing an organic superconductor that operates at room temperature.
A Kaiser Permanente study of 801 pregnant women found a significant link between maternal magnetic field exposure during pregnancy and the development of asthma in their children. Women with high MF exposure were more than three times as likely to have an asthmatic child, highlighting the need for awareness about EMF health effects.
The University of Cincinnati has developed a lab-on-a-chip sensor that can detect highly electronegative heavy metals like manganese in human blood serum in just ten minutes. This sensor is environmentally friendly and child-friendly, making it an attractive option for clinical, occupational, and research settings.
A recent study found that hydroelectric reservoirs emit significantly less carbon dioxide and methane than previously estimated, with an annual emission of 48 million metric tons. The research analyzed 85 globally-distributed reservoirs and concluded that these systems are not major contributors to the greenhouse gas problem.
Researchers found that combining tamoxifen with dasatinib reverses chemo-resistance caused by cancer-associated fibroblasts. The combination normalized glucose intake and reduced mitochondrial oxidative stress, leading to nearly 80% cell death.
The International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) will enroll 8,000 patients with stable ischemic heart disease. The study aims to determine whether a routine early invasive strategy is superior to a conservative approach in improving angina-related quality of life.
A new study finds that workers who receive settlements for painful on-the-job back injuries experience worsening financial and domestic problems over time. Younger workers and those with lower incomes are particularly affected, with significant increases in financial difficulties and legal actions.
The Census of Marine Life project has identified human activities affecting deep-sea habitats, including waste dumping, resource exploitation, and climate change. The study predicts that these impacts will lead to biodiversity loss and ecosystem disruption in the short and mid-term.
Scientists at University of Nevada, Reno observed an upper limit of three on the number of fault jumps through which an earthquake is likely to rupture. This finding helps reduce uncertainties in estimating earthquake sizes in complex fault systems.
Research confirms long-term azithromycin treatment increases infection with nontuberculous mycobacteria, a serious complication in cystic fibrosis. Azithromycin blocks autophagy, impairing immune cells' ability to kill bacteria.
The Hastings Center Report examines the social challenges of synthetic biology, including ethical considerations and regulatory implications. Experts discuss guidelines for emerging technologies, highlighting the need for responsible stewardship and balanced analysis.
Researchers reveal how bats interpret echoes to distinguish targets from background clutter, using a mental fingerprint of emitted sound and echo. The bat's neurons process the information in as little as 3 microseconds, allowing for precise targeting even in complex environments.
Researchers at Rice University have discovered a way to transform sheets of graphite oxide into functional supercapacitors by writing patterns into them with a laser. The devices exhibit good electrochemical performance without the need for chemicals, comparable to existing thin-film micro-supercapacitors.
Researchers found that plants like Arabidopsis thaliana can speed up DNA duplication, leading to increased growth and seed production after being grazed. This process allows plants to increase their DNA content, protein production, and cell size, ultimately boosting their reproductive success.
The Juno Mission aims to study the origin and evolution of Jupiter, helping scientists understand planetary formation and the solar system. The spacecraft will orbit Jupiter's poles 33 times, measuring magnetic activity and water content in its atmosphere.
A national study found that hospitalists' patients have higher Medicare costs in the 30 days after discharge due to increased post-discharge medical utilization and cost shifting. Hospitalist care was initially thought to reduce overall costs, but the findings suggest otherwise.
Lesser toe deformities, such as hammer toes and claw toes, can cause significant pain and limit activities. Improper footwear is a common cause, while genetic and neuromuscular conditions also play a role. Nonsurgical treatments like pads and gel sleeves can be effective, but surgery may be necessary for severe cases.
A novel nanostructure mimics vascular endothelial growth factor to promote blood vessel growth, potentially treating conditions like peripheral arterial disease. The nanostructure shows promise in restoring blood flow and has a longer half-life compared to the natural protein, enhancing its potency.
Dr. Joanne Jordan has received the 2011 Distinguished Service to Rural Life Award from the Rural Sociological Society for her outstanding contribution to enhancing rural life and rural people through her work on the Johnston County Osteoarthritis Project, which improved health outcomes in rural North Carolinians.
A community hospital implemented a comprehensive CT radiation dose reduction program, reducing effective doses by up to 64% in certain protocols. The program's key strategies included ensuring proper scanner functionality, trained staff, monitoring, and education.
Scientists at the Allen Institute have identified complex cellular patterns in brain development, suggesting multiple mechanisms beyond Reelin involved in proper neuron migration. The findings have major implications for understanding brain disorders like autism.
Researchers at Rice University have created a hybrid graphene film that combines conductivity and transparency, potentially replacing indium tin oxide as a transparent conductive coating in displays. The material outperforms ITO in terms of transparency and conductivity, and is environmentally stable.
Researchers developed a liquid composite material that can restore damaged soft tissue relatively safely and durably. The material, composed of biological and synthetic molecules, was tested in rats and humans, showing promise in facial reconstruction, particularly for soldiers' blast injuries.
Recent research reveals oxytocin's role in promoting approach-related emotions, including envy and gloating, which could have implications for psychiatric treatments. Oxytocin's effects on social behavior are more complex than previously thought.
A study by University of Washington psychologists found that the right match between parenting styles and child's personality leads to fewer depression and anxiety symptoms. Children with good self-control benefit from more autonomy, while those with trouble regulating emotions need more parental guidance.
A Johns Hopkins study found that indoor air cleaners can greatly reduce household air pollution and lower daytime asthma symptoms. However, they did not counter all ill effects of second-hand smoke. The researchers recommend using air cleaners as a temporary tool to achieve a smoke-free environment.
The American College of Physicians and three other organizations issue new clinical recommendations for diagnosing and treating stable chronic obstructive pulmonary disease (COPD). The guidelines aim to help clinicians diagnose and manage COPD, prevent and treat exacerbations, and improve patient quality of life. In contrast, the risks...
Researchers from the University of Missouri-Columbia found that negative physiological changes associated with type 2 diabetes occur in people who transition from high activity levels to inactivity. Adding regular movement to daily routines can help prevent chronic diseases and weight gain, even if it doesn't lead to visible changes.
A new national transplant policy has sliced in half the racial disparities that have long characterized the allocation of lifesaving organs. The researchers attribute the drop to a 2003 decision by the United Network for Organ Sharing (UNOS) to change the relative priority given to tissue matching.
Researchers at ICN2 have developed a new technique to write magnetic data, eliminating the need for cumbersome magnetic fields and providing simple, reversible writing of memory elements. This breakthrough could lead to non-volatile MRAMs, allowing instant power-up and significant energy savings.
A new study demonstrates that even a simple microbe can achieve sophisticated sensory adaptation, allowing its behavior to remain consistent in ever-changing background conditions. Researchers found that E. coli responds to relative changes in sensory inputs rather than absolute concentrations.
The studies focus on positron emission tomography (PET) to differentiate between types of dementia and identify pharmaceuticals to slow dementia progression. PET scores provide a valid biomarker for monitoring Alzheimer's disease progression.
The new discs mimic the natural structure of human discs, with improved mechanical properties over time. This breakthrough could lead to a significant reduction in chronic back and neck pain, allowing patients to maintain their mobility and quality of life.
A new study published in Diabetes Care found that mobile health software helped patients with Type 2 diabetes lower their blood sugar levels by an average of 1.9 percent over a year. The software provided real-time feedback, medication regimens and a virtual coach to help patients manage their condition.
Dr. Devra Lee Davis discusses health risks associated with cell phone use, including brain cancer and long-term implications for young people. She provides recommendations for safe use, such as maintaining distance from the brain and body.
A study found that caregivers and their relatives with mild to moderate dementia have differing perceptions of care quality. The team's results suggest that adult children underestimate the importance of core values held by their relatives, leading to potential miscommunication as dementia worsens.
Scientists have developed a new heart model to investigate the effects of artificial nanoparticles on cardiac function. Exposure to certain types of nanoparticles led to increased heart rates, cardiac arrhythmia, and modified ECG values typical of heart disease.
A clinical trial is underway at the University of Colorado to test a drug that could improve memory and learning in those with Down syndrome. The study, led by Dr. Alberto Costa, aims to enhance brain function and potentially increase hope for those affected.
Researchers at U of M Medical School used advanced MRI technology to develop a better approach to diagnosing epilepsy. The study revealed highly detailed images of brain tissue, allowing doctors to accurately locate scar tissue associated with the condition.
Researchers developed a new catalyst material that converts bio-ethanol into isobutene in one step, reducing costs. This process enables the creation of valuable chemicals such as tire rubber and safer solvents, expanding the applications for sustainably produced bio-ethanol.
Researchers found that a bear bile-derived compound, UDCA, can alter the electrical properties of myofibroblasts to prevent arrhythmia in both fetal hearts and adult hearts after a heart attack. This could lead to new treatments for obstetric cholestasis and post-heart-attack complications.
Researchers propose a new model, 'wrap up', explaining the evolution of low pressure systems. This model addresses weaknesses in the Norwegian meteorological model, providing a better understanding of severe weather conditions.
Researchers found that individuals lacking TLR1 proteins are more susceptible to tuberculosis, leading to decreased immune function. The study suggests a potential approach for personalized therapy and prioritizing drug treatment in developing countries.
New research in the FASEB Journal suggests that nicotine can protect dopamine neurons in the brain from Parkinson's disease. The discovery of how nicotine does this may lead to entirely new types of treatments for the disease.
A new school-based obesity prevention curriculum has been shown to significantly reduce medical costs associated with obesity and eating disorders. The program, Planet Health, was found to prevent 1 case of bulimia nervosa among girls aged 13-17 in each participating school, resulting in an estimated $34,000 in savings per girl.
Researchers propose a new counseling model that views obesity as a result of neurobehavioral processes, rather than personal choice or willpower. The approach highlights three key factors: food reward, inhibitory control, and time discounting, and recommends strategies to help patients overcome these challenges.
A study by Penn State researchers found that people who view negative political ads perceive the ads as having a greater influence on others than themselves. The experiment showed that both supporters and opponents of a presidential candidate believe the ads affect others more than they are affected by them.
The largest-ever map of plant protein interactions has been created, covering 6,205 interactions involving 2,774 individual proteins in the model plant Arabidopsis thaliana. The new network map provides insights into protein functions and compositions, and may help advance efforts to improve crop plants.
A study by Andrew Weng and colleagues identifies insulin growth factor-1 (IGF-1) as a key driver of cancer growth in T cell acute lymphoblastic leukemia. Blocking the IGF-1 receptor improves survival rates in mice, suggesting a potential new treatment strategy.
The American College of Physicians, along with three other medical organizations, has released a joint clinical practice guideline for diagnosing and treating stable chronic obstructive pulmonary disease (COPD). The guidelines recommend obtaining spirometry to diagnose airflow obstruction in patients with respiratory symptoms, but not ...
Scientists found satellite data inaccurately measures aerosols' effect on climate, leading to underestimated cooling effect. Researchers need to combine models with satellite data to improve climate predictions.
Researchers developed a quicker freeze-drying technique that reduces energy and processing time, resulting in freeze-dried salmon cubes with minimal moisture content. These cubes maintain color, rehydrate quickly, and have reduced shrinkage compared to traditional freeze-drying methods.
A new project led by University of Chicago researcher Jean Decety will use fMRI technology to examine the neural circuitry of criminal psychopaths in prisons. The research aims to identify the brain networks necessary for empathy and develop targeted therapies.
The research group has identified a new protein, Pinkbar, that creates planar membrane sheets, modifying the structure of plasma membranes in intestinal epithelial cells. This finding may be linked to various intestinal disorders.