Dimitrios Morikis and Lincoln Johnson aim to create new inhibitors of the complement system to treat the disease, which affects over 1.75 million Americans. The researchers will use computational modeling and virtual screening to identify potential treatments.
A new study reveals that extreme cold temperatures can have a devastating impact on coral reefs, causing widespread death and destruction. The research found that corals depend on symbiotic algae for nutrition, which is inhibited by cold temperatures, leading to a potential net loss of carbon transferred from the algae to the coral.
A study published in The American Journal of Pathology reveals a novel mechanism for pillar formation during intussusceptive angiogenesis in tumors. The researchers found that targeting just one type of blood vessel formation may not be sufficient to slow tumor growth, and instead propose a more tailored approach to anti-tumor therapy.
Georgia Tech professors Paul Houston and C. David Sherrill were named ACS Fellows in 2011 for their work in chemistry, contributing to global challenges like providing clean water and new energy sources.
Researchers found a connection between erectile dysfunction and social networks shared by heterosexual men and their partners. Partner betweenness, where a male partner has weaker relationships with his confidants than his female partner, is linked to increased risk of ED.
Frequent visual field testing in patients with primary open-angle glaucoma may lead to earlier detection of the condition's progression, according to a study published in Archives of Ophthalmology. The researchers found that twice-yearly schedules resulted in earlier detection compared to yearly schedules.
Researchers found identical lead isotopes in ancient rocks from North America and Antarctica, suggesting a connection between the two continents 1.1 billion years ago. This discovery strengthens support for the SWEAT hypothesis and provides critical clues to the geographic relationships between major continents.
A shortage of primary care physicians and limited access to these services are contributing to rising numbers of emergency department visits in the US. The study found that nearly 98% of Americans have health insurance coverage, yet barriers such as wait times and transportation issues remain a major challenge.
A NASA scientist and her colleagues observed for the first time that an earthquake and tsunami can break off large icebergs a hemisphere away. The Tohoku Tsunami in 2011 caused massive waves to reach Antarctica, calving off several chunks of ice that equaled about two times the surface area of Manhattan.
Researchers use Fourier transform infrared-attenuated total reflection spectroscopy to identify infected trees with 95% accuracy. The method is faster and cheaper than current DNA testing, but further differentiation between diseases is needed.
A new study from the University of Haifa found that walking around the ward during hospitalization significantly reduces the length of older patient's stay. The study, which surveyed 485 participants aged 70 and up, found that patients who walked around shortened their hospital stay by an average day and a half compared to those who di...
Male fruitflies experience a prolonged mating period with females after encountering rival males, increasing the length of mating by up to 93% in some species. This 'paranoid' behavior is thought to ensure fertilization before females mate with other males.
A randomized controlled trial found that soy isoflavone tablets did not prevent bone loss or reduce menopausal symptoms in women, contradicting previous hopes for an alternative to estrogen therapy. The study involved 248 women with low bone density and followed them for two years.
Researchers have developed a new resource, mirKO, to investigate the role of microRNAs in human health. The resource provides tools to delete specific microRNA genes in mice or cells, allowing researchers to study their significance and biological function.
Researchers have found that de novo protein-altering mutations account for more than 50% of sporadic schizophrenia cases. These genetic errors are present in patients but not in their parents. The study suggests that many more mutations may contribute to the disease, paving the way for new treatments.
Research suggests a bullying climate may play an important role in student test performance and academic success. Schools with severe bullying climates had significantly lower scores on standardized tests.
A collaborative study between UNC and Duke scientists reveals that disruptions in protein signals can lead to improper mitochondrial distribution during cell division, resulting in reduced ATP levels. This finding has implications for diseases such as cancer and neurodegenerative disorders.
A study published in Nature Genetics identified 49 new significantly mutated genes associated with TCC, including eight genes related to chromatin remodeling. These genetic aberrations were found in 59% of individuals with TCC, suggesting a potential role for UTX gene in bladder cancer classification and diagnosis.
Researchers at Berkeley Lab have discovered a way to create strong, heat-resistant aluminum alloys by controlling nanoparticle size and shape. The alloy's properties are highly dependent on the uniformity of the nanoparticles and their stability when heated.
The UMass Amherst team discovered a fundamental property of microbial nanowires in Geobacter sulfurreducens that allows for long-range electron transport. This breakthrough could lead to cheaper, nontoxic nanomaterials for biosensors and solid-state electronics.
Scientists studied brain cells in rats and found that only place cells were sensitive to height, with weak responsiveness. The brain's sense of space is more accurate in horizontal directions, suggesting a flat map of space for altitude.
Researchers developed a cell-based test that can classify chemicals as sensitizing or non-sensitizing, predicting the strength of allergic responses. This alternative to animal testing aims to reduce suffering from skin conditions such as eczema.
Researchers found a novel system involving Pch2 and Orc1 proteins protecting yeast rDNA from inappropriate meiotic recombination. This protective repeat-associated heterochromatin makes the DNA segments near its boundary particularly vulnerable to recombination.
Research by Dr. Larry D. Rosen highlights both the benefits and drawbacks of social networking for children, including increased narcissism and anxiety, as well as improved empathy and social skills
A new study by Ohio State University researchers found that Nobel Prize-winning ideas in science don't always gain more acceptance over time. Instead, many laureates see a decrease in acceptance for their later work related to the Nobel idea.
Atrial fibrillation increases dementia risk by 40-50% through weakening heart function and inflammation, study suggests. Researchers found a link between the condition and cognitive decline in older adults.
Cyberstalkers increasingly use technology to torment their victims, causing higher levels of stress, anxiety, and trauma. Researchers also found that students who blamed themselves for cyberbullying were more likely to ruminate and suffer serious stress.
Researchers found that diarrhoea is closely linked to changes in faecal bacteria, with the majority of foals developing the condition due to colonisation by E. coli and other bacteria. This suggests that horse breeders should not limit suckling time or use supplements to prevent diarrhoea.
A new study suggests that increases in public health spending result in healthier people, particularly in communities with limited resources. Communities investing more in local public health activities saw significant reductions in mortality from preventable causes of death.
A USC researcher collected samples from floating sediment traps in the San Pedro Basin to study how much carbon is locked up in the ocean. Her findings suggest that the majority of particulate organic carbon falling to the basin floor is marine-derived, acting as a carbon sink taking carbon out of the atmosphere via phytoplankton and l...
Research suggests that almost 1 million US criminal cases are compromised each year due to a lack of understanding about Miranda warnings. According to psychologist Richard Rogers, defendants often incorrectly believe their silence can be used against them in court.
Tropical Storm Emily was formed and morphed into an elongated area of low pressure over the Caribbean Sea. A 60% chance of a comeback is given by the National Hurricane Center due to favorable upper-level winds on the weekend.
The article highlights how Facebook profiles are similar to traditional portraiture, where artists must make rhetorical decisions about representation. The author notes that both Rembrandt's famous works and today's social media profiles strive for mastery over the challenges of representation.
Typhoon Muifa is almost twice as large as Tropical Storm Merbok, with winds extending 220 miles from its center. The storms were captured side-by-side by NASA's Aqua satellite on August 5, 2011, showing Muifa's well-defined eye and stronger organization.
A new study from the University of Michigan Comprehensive Cancer Center confirms that sentinel lymph node biopsy is a safe and effective way to determine the status of regional nodal basins for head and neck melanoma patients. The procedure was found to be accurate in identifying cancerous nodes, with only 4% false-negative results.
Researchers have introduced a scenario that assumes action will be taken to limit emissions, showing a lowest cost option to reduce carbon dioxide in the atmosphere to less than 40% higher than today. The RCP 4.5 scenario includes nuclear and renewable energy, carbon capture and storage, and forest preservation to achieve this goal.
Purdue University scientist William Muir argues that genetically engineered salmon, AquAdvantage (AA), poses little real risk to the environment or human health. Once assessed and deemed safe, AA salmon should be allowed for production and sale in the US to increase food supplies for a growing world population.
Researchers found hunter attitudes toward wolves inconsistent with stewardship, and existing game hunts are not suitable models for a potential wolf hunt. Support for regulated wolf hunting is conditional and varies among respondents.
A UCLA preclinical study found that Intralipid, a man-made fat emulsion, can prevent extensive heart damage and preserve heart function when used during blood flow return after a heart attack. This discovery may introduce a new way to significantly decrease damage to the heart muscle due to reperfusion injury.
A new study suggests that aggressive tree-killing fungi, relatives of modern plant pathogens, played a key role in the demise of ancient conifer forests. The researchers propose that these fungi were triggered by global climate change and contributed to widespread tree mortality during the end-Permian crisis.
Researchers at Johns Hopkins University discovered that the shape of jaw bones in human populations is influenced by both genetic and environmental factors. The study used archaeological jaw bones from two different regions to determine how much of the mandible's shape is plastic, a response to diet, and how much is genetic.
A Michigan State University researcher has developed a web-based genetics curricula with the goal of making the subject more engaging and accessible to students starting in fifth grade. The system, supported by a $2.3 million NSF grant, aims to improve students' understanding of genetic-related concepts.
A new study reveals that gazpacho's vitamin C content and other organic acids decrease significantly after preparation. Peppers and tomatoes have higher levels of these nutrients, while cucumbers contain the lowest amount. The authors suggest consuming gazpacho immediately or preserving it correctly to maintain its antioxidant properties.
Warmer cloud top temperatures suggest a decrease in cloud heights and storm energy for Tropical Storm Eugene. The storm's maximum sustained winds reached near 65 mph on August 5.
Researchers found that individuals who trust in a benevolent God tend to worry less, while those with negative beliefs report higher levels of worry. The study suggests integrating patients' spiritual beliefs into treatment regimens can improve mental health outcomes.
A consumer psychologist suggests that people can eat healthier without conscious thought by modifying their surroundings. Simple strategies include eating off salad plates, keeping unhealthy foods out of sight, and eating in the kitchen or dining room, leading to weight loss success.
A new study reveals that weight loss of 5% improves erectile function, sexual desire, and lowers urinary tract symptoms in obese men with type 2 diabetes. The study found that modest weight loss resulted in rapid reversal of sexual and urinary problems within 8 weeks.
A team of researchers at National Jewish Health discovered a type of B cell that may contribute to autoimmune disease, particularly in women. These cells produce autoantibodies and are more prevalent in elderly female mice, young and old mice prone to autoimmune disease, and humans with autoimmune diseases.
Seasonal dark features on Martian slopes suggest the presence of salty water, which could indicate a habitable environment. The recurring flows may be formed by fluid seeping down slopes and have characteristics that fit better with briny water explanations.
A novel DNA-sensing mechanism plays a role in the innate immune response to Plasmodium falciparum, the parasite that causes malaria. The study identifies an unknown receptor coupling to molecules linked with DNA-mediated type I interferon production, suggesting a broader impact on infectious diseases.
Increased hand hygiene knowledge among healthcare workers and elementary school children significantly reduces the risk of transmitting infections. A targeted intervention program showed a 66% decrease in pupil absences after teaching hand disinfection theory and practice.
Scientists at UMass Chan Medical School discovered a novel DNA-sensing pathway that contributes to the triggering of an innate immune response in malaria. This pathway leads to the production of excessive type-1 interferon, causing inflammation and fever in patients.
Researchers at Montana State University found a surprising condition where common lung mold causes a shortage of oxygen in the lungs. The study reveals that the mold's fermentation can influence the host immune response and adapt to low oxygen levels.
A UK study found that pulse oximetry screening detected 75% of critical cases and 49% of all major congenital heart defects in newborns. Combining pulse oximetry with routine ultrasound and physical examination improved detection to 92%, avoiding undiagnosed deaths.
Researchers at Vanderbilt University have created microelectronic devices out of thin films of nanodiamond, which can operate at higher speeds and require less power than silicon-based devices. The diamond-based devices are also resistant to radiation damage and can function in extremely high or low temperatures.
Researchers develop new method to link climatic records with plant and animal responses to climate change, enabling precise dating of archaeological sites. This breakthrough enables detailed analysis of human occupation patterns in Britain during the Ice Age.
A new study finds that retroflexion technique during colonoscopy on the right side of the colon detects additional adenomatous polyps in approximately four percent of patients, comparable to a second forward-view colonoscopy. The technique is safe and achievable in 95% of patients.
A new study by Cornell University researchers found that US physicians spend nearly $61,000 more annually on administrative expenses due to the complexity of US health insurance systems. This burden disproportionately affects nurses and medical staff in the US.
Research suggests that predictive genetic testing in children may have benefits, including identifying individual's inherited vulnerabilities to diseases and enabling early health interventions. However, existing guidelines warn of potential psychological harm, which critics argue is often based on speculation rather than evidence.
Researchers develop a method to convert human skin cells into neurons, offering a potential shortcut for generating replacement therapies. The new approach has already yielded insights into Alzheimer's disease and could be used for testing new drug candidates.