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Science News for June 8, 2011


Circulating levels of a lung protein found to be 'strongly predictive' of cardiovascular disease

A study found that circulating levels of surfactant protein-D were associated with cardiovascular disease and mortality in patients with coronary artery disease, independent of other risk factors. Blood levels of SP-D increase when the lungs are inflamed, such as in smokers or those with chronic lung conditions like COPD.

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·DateJun 8, 2011

Treating children's eye infections without surgery

A new study published in Ophthalmic Plastic & Reconstructive Surgery suggests that medical management may be preferred over surgery for children with orbital cellulitis. The research identifies the size of a subperiosteal abscess (SPA) as a determining factor in whether surgery is required for treatment.

SourceLifespan·JournalOphthalmic Plastic and Reconstructive Surgery·DateJun 8, 2011

REDD+ strategies lack plan for agriculture

A new analysis finds that most countries participating in REDD+ cite agriculture as the main cause of deforestation, but few provide details on how to address this issue. Countries pursuing food and biofuel production policies are intensifying agriculture-related pressures on forest lands.

SourceBurness·DateJun 8, 2011

Ordered fear plays a strong role in market chaos

A study analyzing stock market volatility over 50 years reveals the existence of hidden temporal order and high correlations between fear-driven market fluctuations and price variations. This discovery implies that traditional investment strategies should incorporate consideration for the 'volatility of volatility' in portfolio design.

SourceAmerican Institute of Physics·JournalAIP Advances·DateJun 8, 2011

New 3-D tumor model

A team of scientists has created a new 3D tumor model that can grow in a realistic and easily accessible substrate, speeding up cancer drug discovery. The model's 3D nature provides a more accurate representation of how tumors grow in the body, reducing the likelihood of promising drugs failing during animal testing.

SourceAmerican Institute of Physics·JournalBiomicrofluidics·DateJun 8, 2011

The cellular root of colorectal cancers?

A study published in Cancer Research found a link between the ABCB5 marker and treatment resistance in colorectal cancers. The researchers discovered that eliminating cells expressing ABCB5 is crucial for successful treatment, supporting the cancer stem cell hypothesis. This finding has significant translational and therapeutic relevance.

SourceBoston Children's Hospital·JournalCancer Research·DateJun 8, 2011

Genes provide landmarks on the roadmap of autism

Researchers at Baylor College of Medicine and Texas Children's Hospital mapped the interactome for autism spectrum disorder, identifying hundreds of new protein interactions. The study also confirms previously known connections and reveals unsuspected connectivity between genes associated with idiopathic and syndromic autism.

SourceBaylor College of Medicine·JournalScience Translational Medicine·DateJun 8, 2011

Unraveling the complex genetics of autism

Researchers identified rare genetic variations in children with autism spectrum disorders, including duplications and deletions of DNA regions. These findings suggest a diversity of genetic causes for the disease and highlight the importance of targeting specific subtypes of autism for effective treatment.

SourceCell Press·JournalNeuron·DateJun 8, 2011

NIST 'catch and release' program could improve nanoparticle safety assessment

Scientists at NIST have developed a method to capture metal-based nanoparticles on a surface and release them at the desired moment, allowing for effective assessment of their toxicity in cell cultures. This approach enables precise delivery of particles to cells, mimicking real-world encounters, and reducing clumping issues.

SourceNational Institute of Standards and Technology (NIST)·JournalApplied Surface Science·DateJun 8, 2011

Water's surface not all wet

Researchers found that only one-quarter of water molecules at the surface exhibit characteristics of both gas and liquid phases, allowing for new understanding of chemical reactions and atmospheric balance. The study provides a framework for investigating other interfaces, such as those in living cells.

Citrate key in bone's nanostructure

Researchers at Ames Laboratory discovered citrate plays a crucial role in the nanostructure of bones, providing stiffness and preventing crack propagation. Higher citrate concentrations result in thinner apatite nanocrystals, which are more resistant to brittleness.

SourceDOE/Ames National Laboratory·JournalChemistry of Materials·DateJun 8, 2011

Historic first images of rod photoreceptors in the living human eye

Researchers successfully imaged rod photoreceptors in the living human eye for the first time, revealing cellular structure with unprecedented detail. This breakthrough enables earlier diagnosis and treatment of degenerative eye disorders, potentially leading to more effective sight-saving interventions.

SourceOptica·JournalBiomedical Optics Express·DateJun 8, 2011

Moderate to intense exercise may protect the brain

A new study found that older adults who engage in regular moderate to intense exercise are 40% less likely to develop small brain lesions, also known as 'silent strokes'. This reduces the risk of falls, memory problems, dementia, and stroke. Exercise does not appear to have a similar benefit for those with limited access to healthcare.

SourceAmerican Academy of Neurology·JournalNeurology·DateJun 8, 2011

Breast cancer drug pushes colon cancer cells to their death

A new combination of a breast cancer chemotherapy agent and an artificial antibody has been tested in clinical trials, showing promising results in targeting colon cancer cells. The treatment, which combines lapatinib with monoclonal antibodies, has the potential to provide hope for patients with treatment-resistant cancers.

SourcePenn State·JournalScience Translational Medicine·DateJun 8, 2011

Mountain pine beetle activity may impact snow accumulation and melt, says CU-Boulder study

A CU-Boulder study indicates that mountain pine beetle infestations could lead to earlier snowmelt and increased water yields. The research found that dead trees with red needles accumulated more snow than living stands, while those with gray phase trees melted faster due to reduced snow interception and increased solar radiation.

SourceUniversity of Colorado at Boulder·JournalEcohydrology·DateJun 8, 2011

Blood simpler

Researchers at UCSD have discovered a novel signaling pathway and gene, Wnt16, essential for the formation of hematopoietic stem cells in vertebrate embryos. This breakthrough has significant implications for developing stem cell-based therapies for diseases such as leukemia.

Lifelong gap in health between rich and poor set by age 20

A study by McGill University found that socio-economic status affects Canadians' health-related quality of life from a young age. The research analyzed data from 17,000 Canadians and found that poorer individuals start out less healthy than their wealthier counterparts and remain so over their lifetimes.

SourceMcGill University·JournalJournal of Epidemiology and Community Health·DateJun 8, 2011