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Science News for May 25, 2011


8 hours of resistance

Researchers discovered that cancerous cells quickly divide after receiving a growth factor signal because their p53 gene is defective. Healthy cells, on the other hand, wait eight continuous hours before dividing to ensure they receive necessary signals.

SourceWeizmann Institute of Science·JournalMolecular Cell·DateMay 25, 2011

Rethinking extinction

A recent study by McGill biologist Jonathan Davies and colleagues suggests that the criteria for assessing risk of extinction in plants should be revised. The researchers found that species with small population sizes, even if not limited to a specific geographical range, can also be at high risk of extinction due to their youth.

SourceMcGill University·JournalPLOS Biology·DateMay 25, 2011

Immune system release valve

Researchers discovered that caspase-8, an enzyme previously thought to only prevent inflammation through apoptosis, can also control inflammation by destroying a protein called RIP1. This new mechanism could lead to the development of effective therapies for inflammatory disorders like rheumatoid arthritis and inflammatory bowel disease.

SourceWeizmann Institute of Science·JournalImmunity·DateMay 25, 2011

Monkeys can play Monday morning quarterback too

A Yale University study found that monkeys can imagine different outcomes, a process linked to the brain's prefrontal cortex. This discovery may help researchers develop treatments for diseases such as depression and schizophrenia, which often involve obsessive thoughts about past choices.

SourceYale University·JournalNeuron·DateMay 25, 2011

New software tool helps evaluate natural cooling options for buildings

A new software tool from NIST assesses the climate suitability of natural ventilation in office buildings, considering adaptive thermal comfort standards and humidity levels. The Climate Suitability Tool provides estimates of ventilation rates and effective cooling hours, aiding architects in designing more efficient ventilation systems.

Losing more than 15 percent of body weight significantly boosts vitamin D levels in overweight women

A year-long study of 439 overweight-to-obese postmenopausal women found that losing more than 15% of their body weight significantly increases circulating vitamin D levels. This effect is independent of dietary intake and is not linear, with more substantial increases found in those who lose greater amounts of weight.

SourceFred Hutchinson Cancer Center·JournalAmerican Journal of Clinical Nutrition·DateMay 25, 2011

Listening with 1 atom

Researchers at the Weizmann Institute developed a quantum version of a locked-in amplifier using a single atomic-ion detector, achieving spatial resolution of just a few nanometers. This technique improves the sensitivity of quantum sensors by around 100 times.

Vitamin D increases speed of sperm cells

Researchers at the University of Copenhagen found a positive correlation between serum vitamin D levels and sperm motility in healthy men. Laboratory stimulation with activated vitamin D also increased forward movement of human spermatooza, sparking new hypotheses about the role of vitamin D in male reproduction.

SourceUniversity of Copenhagen·JournalHuman Reproduction·DateMay 25, 2011

Tufts graduate students receive $10,000 prizes

Three teams of Tufts graduate students have won $10,000 from the Dow Sustainability Innovation Student Challenge Award program for their research on clean water, renewable energy, and green medical technologies. The winners will use their prize money to develop solutions to pressing global challenges.

Thoughts that win

A meta-analysis of 32 sport psychological studies found that self-talk improves sport performance, but different types of self-talk work better for different tasks. Instructional self-talk is more effective for fine skills, while motivational self-talk boosts confidence for endurance tasks.

SourceAssociation for Psychological Science·JournalPerspectives on Psychological Science·DateMay 25, 2011

Targeted adalimumab treatment can optimize long-term outcomes for patients with early RA

A study of 1032 patients with early RA found that initial treatment with adalimumab plus methotrexate provided high levels of disease control, with 44% achieving sustained low disease activity. Patients who continued treatment maintained good clinical and radiographic responses, even after withdrawing treatment.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·JournalAnnals of the Rheumatic Diseases·DateMay 25, 2011

Global warming may affect the capacity of trees to store carbon, MBL study finds

A MBL study found that warming causes more nitrogen to become available to trees, allowing them to grow faster and store more carbon. This is a positive effect on carbon storage, but the overall impact of global warming on forest ecosystems will also depend on other factors such as water availability and atmospheric CO2 concentration

SourceMarine Biological Laboratory·JournalProceedings of the National Academy of Sciences·DateMay 25, 2011

US study shows that tofacitinib is an efficacious treatment for active RA

A Phase III study presented at EULAR 2011 found that tofacitinib achieved significant improvements in symptoms and activity scores for patients with active rheumatoid arthritis (RA), including improved ACR20 responses in 58.3% of patients, and a higher proportion of patients achieving ACR50 and ACR70 responses compared to placebo

SourceEuropean Alliance of Associations for Rheumatology (EULAR)·JournalAnnals of the Rheumatic Diseases·DateMay 25, 2011

Large NIH funded rehabilitation study looks at getting stroke patients back on their feet

The study, which compared two types of physical therapy, found that patients who received at-home strength and balance training made significant improvements in walking speed and mobility, with results lasting up to one year. The findings suggest that conventional wisdom about recovery being limited to six months may be incorrect.

SourceNIH/National Institute of Neurological Disorders and Stroke·JournalNew England Journal of Medicine·DateMay 25, 2011

Drug may help overwrite bad memories

A study published in the Journal of Clinical Endocrinology & Metabolism found that metyrapone, a stress hormone-reducing drug, can impair memory recall of negative events by manipulating cortisol levels close to formation. This could lead to a better understanding of how to treat post-traumatic stress disorder

SourceUniversity of Montreal·JournalThe Journal of Clinical Endocrinology & Metabolism·DateMay 25, 2011

High-fat diet during pregnancy programs child for future diabetes

A new University of Illinois study published in the Journal of Physiology found that a high-fat diet during pregnancy programs a woman's baby for future diabetes. Exposure to such a diet modifies gene expression in the livers of offspring, increasing the likelihood of early insulin resistance and diabetes.

Combo method reveals cells' signal systems

Researchers at Uppsala University have developed a new method to study signal systems in individual cells, revealing the molecular effect of drugs and facilitating the discovery of targeted pharmaceuticals for cancer treatment. This tool provides insight into how cancer cells communicate with normal cells and exploit their functions.

SourceUppsala University·JournalPLOS ONE·DateMay 25, 2011

Healthy gut flora could prevent obesity

A study by Caroline Karlsson found that rats fed a specific lactic acid bacteria HEAL19 had significantly less weight and inflammation compared to those without the bacteria. Additionally, babies born vaginally have lactobacilli in their gut flora as early as two days after birth.