Dr. Piyali Dasgupta received a three-year grant to investigate the anti-cancer activity of capsaicin in small cell lung cancer patients. The study aims to improve chemotherapy treatment outcomes, which often relapse quickly and become unresponsive.
Dr. Joseph Ciolino, a Mass. Eye and Ear ophthalmologist, has received the Research to Prevent Blindness (RPB) Career Development Award to support his translational projects in keratoprosthesis and ocular drug delivery. The award aims to attract young physicians and scientists to eye research.
New research warns that Asia cannot achieve its climate and poverty reduction goals unless women's rights to forest and land resources are recognized. Women continue to be marginalized and excluded from decision-making processes in resource management, leading to environmental degradation and food insecurity.
A new study finds CPAP treatment significantly reduces symptoms and improves quality of life in patients with mild to moderate obstructive sleep apnea (OSA) and daytime sleepiness. The study's results suggest that CPAP therapy is highly effective in treating this largest segment of the OSA population.
The study found that while initial results of 2-level axial lumbar interbody fusion were promising, complications arose within 2 years, including screw breakage and rod detachment. Solid spinal fusion was achieved in only 8% of patients at 24 months postoperatively.
Deer hinds in dominant positions select nutrient-rich foods, outperforming subordinates with lower-quality options. The study demonstrates preferential access to high-energy food sources, improving body condition and milk production.
Researchers at RHIC and LHC collaborate to recreate extreme conditions of early universe, studying quarks and gluons in a nearly frictionless liquid. Theoretical approaches using string theory reveal intriguing connections between QGP and conventional plasmas, superconductors, and atoms.
Researchers identified genetic markers influencing protein levels regulating oestrogen and testosterone in the bloodstream, near genes related to liver function and type 2 diabetes. These findings highlight an important connection between metabolic and reproductive systems in men and women.
Research suggests that firms with political connections often hold excess cash, which may be used to support politicians' agendas rather than maximize profit. Poor corporate governance and lack of transparency are also common in these firms, leading to a deadlock between minority shareholders and large shareholders.
Researchers found that severe influenza infection doubles the odds of developing Parkinson's disease later in life, whereas a typical case of red measles as a child reduces the risk by 35%. The study also suggests an association between high-intensity vibrations and increased Parkinson's risk.
Tropical Depression Khanun made landfall in western South Korea on July 19, bringing heavy rainfall and thunderstorms. The satellite tracked the northeastern progression of the cyclone as it moved toward North Korea and northeastern China, eventually dissipating due to atmospheric conditions.
A new study found that Cognitively-Based Compassion Training (CBCT) improved the mental and physical health of adolescents in foster care by reducing anxiety and increasing feelings of hopefulness. CBCT also reduced inflammation levels, which is a fundamental risk factor for chronic illnesses.
The first cross-disciplinary conference on Public Participation in Scientific Research will bring together experts from various fields to share ideas and form new communities. Citizen science projects have recruited non-specialists to contribute to real scientific questions, multiplying data collection by orders of magnitude. The confe...
The Massachusetts Eye and Ear Infirmary has been awarded a $110,000 grant from Research to Prevent Blindness to conduct research on the causes, treatment and prevention of blinding diseases. The grant will be directed by Dr. Joan Miller, who leads the Mass. Eye and Ear/Mass General Department of Ophthalmology.
Researchers analyzed images of Titan's river networks, finding that they resemble early stages of terrestrial rivers' evolution. In some regions, rivers have caused little erosion, raising questions about Titan's geologic past and potential processes such as tectonic upheaval and icy lava eruptions.
A new study found that vitamin D deficiency is associated with worse lung function and faster decline in smokers. Vitamin D sufficiency was linked to improved lung function and reduced rate of decline.
Researchers identified 12 genetic markers associated with sex hormone-binding globulin (SHBG) levels, which regulate testosterone and estrogen in the bloodstream. The study found that SHBG levels are influenced by multiple factors, including genes related to liver function, metabolism, and type 2 diabetes.
A Rutgers University study suggests that poor mothers are more likely to be classified with generalized anxiety disorder due to poverty rather than mental illness. The research found no evidence of a link between anxiety and parenting stress in these mothers.
A new protocol has excellent results and should become the standard of care for treating severe heart attacks. Paramedics trained to read ECGs expedite treatment by evaluating patients with chest pain and restoring blood flow to the heart within 30 minutes.
A new collaboration between DNDi and Cipla aims to develop a 4-in-1 ARV combination product for young children with HIV/AIDS, addressing the gap in current treatments. The goal is to provide safe, potent, child-friendly treatment combinations to accelerate care provision for infants and toddlers living with HIV/AIDS.
UCLA researchers have created a new type of transparent solar cell that can generate electricity while still allowing people to see outside. The cells, made from a photoactive plastic, absorb mainly infrared light and have nearly 70% transparency to the human eye.
Research published in the FASEB Journal found that pregnant mice exposed to diesel exhaust were more likely to have obese offspring with insulin resistance. The study suggests a link between air pollution exposure in utero and metabolic disorders in adulthood. Males were particularly affected, while females only showed increased weight...
An anti-tau treatment called epithilone D (EpoD) has shown promise in preventing and intervening the progress of Alzheimer's disease in animal models by improving neuron function and cognition. The drug aims to stabilize microtubules, which support the transport of essential nutrients and information between cells.
A 2010 California whooping cough epidemic highlighted the importance of vaccination for adults, pregnant women, and infant contacts. The disease had the highest incidence in infants under 6 months, with Hispanics being most affected in this age group, while Whites were most affected among children and adolescents.
A University of Michigan report found that Generation X is lukewarm about climate change, with a small but statistically significant decline in concern between 2009 and 2011. Only 5% of surveyed Gen Xers were alarmed, while 18% were concerned, with education and scientific knowledge being key factors in explaining levels of concern.
The Harvard Wyss Institute is developing a smart suit that improves physical endurance for soldiers by providing efficient actuation and joint support. The wearable system, made from soft, stretchable assistive devices, detects fatigue and boosts balance through low-level mechanical vibrations.
Researchers have unraveled the mystery of a unique virus-coping mechanism, revealing a crucial role for motif D in accurately replicating genetic material. This discovery holds promise for improving existing vaccines and designing new ones against RNA viruses that eluded vaccination strategies.
The UGA team created a single-step method to rapidly detect viruses, bacteria, and chemical contaminants using nanotechnology. They successfully detected compounds in highly diluted samples and mixtures with dyes, suggesting the technology can be used for food, blood, saliva, and urine testing.
Researchers at Arizona State University are developing a game-changing approach for drought monitoring using satellite detection and hydrologic models. The project aims to provide timely detection of drought events with high accuracy, enabling proactive decision-making for national water managers, irrigation districts, and policymakers.
Researchers identified two enzymes, t-PA and MMP-3, that promote injury severity following traumatic brain injury (TBI). Inhibiting these enzymes may protect the brain from TBI by blocking the activation of MMP-3, which causes damage. The study provides a promising therapeutic target for treating human TBI.
The TRMM satellite observed hurricane remnants dissipating in cool Eastern Pacific waters due to upper-level winds and surface temperatures below the necessary threshold for tropical cyclone maintenance. The remnants contained only light to moderate rainfall, located north of the low-pressure center.
Researchers implemented a community-based model, where volunteers provided basic care to HIV patients, achieving equivalent viral load results as hospital-based programs. After two years, 93% of patients showed viral suppression.
Researchers are developing smaller, lighter antennas with directional beamforming to increase user capacity by 50-100 times in the millimeter-wave spectrum. The project aims to relieve pressure on 4G wireless networks and offer tremendous value to the $1 trillion cellular industry.
Researchers at UT Dallas discovered that nerve stimulation can reorganize the brain, leading to potential new treatments for stroke, tinnitus, autism, and other disorders. The technology involves pairing vagus nerve stimulation with specific experiences, such as movements or sounds, to alter brain activity.
A new study from Lund University in Sweden has found that co-infection with mild HIV-2 can slow the development of AIDS in HIV-1-infected patients. The study suggests that HIV-2 can activate cellular reactions that naturally check the development of AIDS, leading to better preventive measures and treatments.
The Georgetown University Medical Center has established a first-of-its-kind center for treating and researching Huntington's disease. The center will provide comprehensive care, education, and research to patients and families affected by the disease.
New studies examine the role of flirtation in negotiations, finding it signals self-interest and competitiveness; individuals concerned with future consequences exercise more and adopt healthier habits; shooter biases may be driven by interpersonal threats rather than culture or race; husbands and wives express love differently in marr...
A study found that rituximab, an immune drug, helped patients with serious kidney disorder idiopathic membranous nephropathy experience remission, even when standard therapies failed. The treatment was safe and well-tolerated, with all patients achieving complete or partial remission over time.
Researchers at Rice University will study how bacterial decision-making occurs at the molecular level, aiming to improve medical applications and environmental remediation. The project combines computational and experimental techniques to bridge the gap in understanding biological systems.
Researchers have developed a new technology that allows for an individualized map of the DNA within a single sperm cell, providing insights into genetic diversity and potential applications in reproductive disorders. This technology could also be used to characterize differences in cancer cells taken from patients.
Researchers have designed an ultracapacitor that maintains a near-constant voltage, enabling its use in low-voltage electric vehicle circuits and handheld electronics. The device achieves this through an electromechanical system that slowly lifts the core out of the electrolyte solution as charge is released.
A new Penn study of 154 participants with chronic HCV found that silymarin supplements offered no significant improvements in liver disease treatment. The trial tested higher-than-normal doses of silymarin and concluded it had no impact on ALT levels or quality-of-life measures.
A new report identifies seven key areas where funding and political will are crucial to ending the AIDS epidemic. The report outlines a comprehensive plan for achieving an AIDS-free generation, including renewed scientific research and implementation of proven treatment tools.
Researchers at Stowers Institute for Medical Research have developed a novel approach to count fluorescent molecules in a cluster, resolving the long-standing debate on centromere structure. By applying this method to yeast cells, they found that centromeric nucleosomes change their structure during cell division.
A joint study by University of Nottingham and Unilever found that fat in food reduces brain activity responsible for processing taste, aroma, and reward. The research provides insights into making healthier, less fatty food products with better taste and enjoyment.
Researchers found that human placenta-derived endothelial colony-forming cells (ECFCs) are more proliferative and better at forming new blood vessels than those derived from umbilical cord blood. The study, published in Cell Medicine, suggests that the placenta could be an abundant source of ECFCs for therapeutic use.
A new study reveals that hundreds of random mutations in leukemia cells are linked to aging, not cancer. Researchers found that even healthy individuals accumulate genetic changes over time, which can increase the risk of developing acute myeloid leukemia (AML).
Researchers at UC San Diego identified a key enzyme in malaria parasites that could lead to new anti-malarial drugs. The team discovered a selective inhibitor, ML276, which stops parasite growth even in resistant strains.
A new study reveals a higher rate of elder abuse among Latino communities, with 10.7% experiencing physical abuse and 9% experiencing sexual abuse in the last year. The study highlights the need for culturally competent programs to raise awareness and prevent elder abuse within these communities.
A team of scientists has discovered an epigenetic enzyme that doubles the output of thousands of different genes in male fruit flies to compensate for their single X chromosome. The study found twice as many DNA-transcribing proteins attached to the male X chromosome compared to females.
A new study found that menu labeling in King County, Washington, resulted in improved nutritional profiles for some chain restaurant entrées, with decreases in energy, saturated fat, and sodium content. However, the majority of entrées continued to exceed recommended guidelines, highlighting the need for more moderate options.
A team of scientists led by Robert Young is working on developing small molecule compounds and nano-medicines that stimulate bone regeneration, aiming to improve understanding of bone renewal biology and promote bone repair and regeneration. The grant is part of a $7 million funding package targeting bone health research.
An interdisciplinary research team from UMass Amherst and Harvard warns that federal regulators need to improve how they track security and privacy problems in medical devices. Despite a high prevalence of recalls related to software, the current classification methods are not well suited to emerging types of device malfunctions.
Researchers at Henry Ford Hospital discovered that African Americans with throat cancer who are HPV positive have significantly better overall survival rates compared to those without HPV. The study also found that African Americans with late-stage oropharyngeal cancer who are HPV negative face a higher risk of death.
A study by University of Michigan researchers found that an inflammatory pathway involving Interleukin-6 drives resistance to Herceptin in HER2-positive breast cancers. Blocking this pathway with a drug improved the treatment's effectiveness, and also prevented cancer stem cells from forming.
A Kansas State University research team has developed an improved method for detecting and measuring bridge damage using a bridge health index. The index provides a more objective way to determine and compare bridge damage, allowing inspectors to input parameters and receive a numerical value indicating the bridge's health.
Researchers at KAIST used triangular shapes to guide axon growth in a dish, finding that smaller vertices were more effective in inducing growth. The study aims to develop a reproducible neural circuit model for learning and memory studies as well as drug screening applications.
A comprehensive review of biomass feedstock characterization is crucial for developing biotechnology approaches to bioenergy and bioproducts. Researchers describe formulation, pretreatment, and densification options to improve biomass specifications for co-firing high percentages with coal.
Research suggests that fragmented sleep patterns are associated with a higher risk of being placed in a nursing home or assisted living facility. Studies have also linked insufficient sleep to chronic diseases and conditions such as diabetes, cardiovascular disease, and depression.
A recent study has questioned the safety and effectiveness of commonly prescribed kidney disease drugs, which may cause unexpected harm to blood vessels. The study found that these drugs did not substantially reduce serum phosphorus levels and may be associated with cardiovascular problems in patients with chronic kidney disease.