Researchers found that flies lacking a key gene associated with RLS exhibit sleep disturbances and restlessness, similar to human patients. The study suggests a genetic basis for RLS and offers new insights into the disease's pathophysiology.
A new study suggests that chronic hepatitis B virus infection may be as high as 2.2 million cases in the US, with foreign-born individuals contributing significantly to this burden. The prevalence is higher than previously reported and affects up to 400 million individuals worldwide.
Cyclone Freda intensified over the Southern Pacific Ocean due to warming waters, with NASA satellites measuring increased rainfall and a widening eye. The storm's maximum sustained winds reached 105 knots, posing a threat to Vanuatu with heavy rainfall and gusty winds.
Researchers at Johns Hopkins Medicine developed a method to track liver tumors' response to chemotherapy using paired CT scans, allowing for immediate feedback on treatment effectiveness. This technique has the potential to save patients from delayed diagnosis and reduced treatment efficacy.
A study published in Archives of General Psychiatry suggests that economic conditions during infancy may contribute to behavioral problems in adolescence. The research found a strong correlation between unemployment rates during infancy and increased odds of substance use, delinquent behaviors, and other issues.
A Johns Hopkins study found that using robot-like devices to disperse hydrogen peroxide vapor enhances hospital disinfection, reducing multiple-drug-resistant bacteria by 64% and patient colonization risk by 80%. The technology improved infection control practices, combining standard cleaning with technological solutions.
Recent media reports have created a perception of a global increase in jellyfish. However, a new study suggests that these trends may be overstated. The research found that global jellyfish populations undergo concurrent fluctuations with successive decadal periods of rise and fall.
A study published in PNAS found that modern humans with feet adapted for terrestrial bipedalism can still climb trees effectively. Researchers observed extreme dorsiflexion and longer muscle fibers in climbing individuals, challenging the idea that a terrestrially adapted foot excludes arboreal behavior.
Researchers have provided definitive evidence that NMDAR receptors are crucial for pruning synapses in newborn mammals' brains. This discovery sheds new light on the neural basis of autism and schizophrenia. The study used a mouse model with brain cells lacking or containing NMDARs to demonstrate the receptor's direct role in synaptic ...
A new study finds that climate warming is allowing bark beetles to thrive in previously inhospitable high-elevation forests, posing a significant threat to whitebark pine ecosystems. The insects are attacking trees with weakened defenses, leading to potential cascading effects on mountain ecosystems.
A new study shows that exposure to cosmic radiation in space can increase the risk of developing Alzheimer's disease. Researchers found that high-mass particles, like iron, can penetrate spacecraft shielding and cause neurological impairment in animal models.
Research from Brigham and Women's Hospital found that patients taking generic antiepileptic drugs are 50% more likely to stop their medication if the pills differ in color. This highlights the importance of pill similarity in improving adherence rates.
Researchers estimate naloxone distribution could prevent 6.5% of all overdose deaths by providing a cost-effective way to reverse opioid overdoses. Quadruple doses of seasonal flu vaccine may better protect HIV-infected patients from serious illness or death, but evidence for quality impact is limited.
Depression in Medicare recipients over 65 is associated with prevalent mild cognitive impairment (MCI) and increased dementia risk. The study found that depression was related to higher MCI and dementia risks, as well as progression from MCI to dementia.
A recent study used bird watching records to build the first bird watching database in China, finding new national-level records and a trend of species moving to higher latitude and elevation regions. The database provides valuable data for scientific research on ecosystem health and biodiversity.
Researchers found that excessive habitat heterogeneity may lead to a decrease in species diversity, contradicting current conservation practices. The study provides important insights for selecting and managing conservation areas.
The UVOT telescope on NASA's Swift satellite has captured over 100 breathtaking images of the cosmos, including comets, star clusters, and supernova remnants. These images provide valuable data for scientists studying gamma-ray bursts, stellar evolution, and the properties of rare stars.
A recent study found that tumor boards have a modest association with the types of treatments patients receive for certain cancers. For example, lung cancer and prostate cancer patients were more likely to receive higher-quality care when treated at hospitals with tumor boards. However, other types of cancer care remained unaffected by...
A study by the University of Vigo found that 56.1% of female students are binge drinkers, compared to 41.3% of males. Female students also exhibit a higher risk of developing unhealthy attitudes towards food and exercise.
A NTU research team discovered massive earthquakes left clear ground scars in central Himalayas, hinting at a higher earthquake risk. The study challenges previous assumptions about blind quakes and suggests areas west or east of the 1934 Nepal ground rupture are now at greater risk.
In a recent discovery, botanists have identified three new species of cave-dwelling nettles in the Guangxi province of China. These plants thrive in extremely low light conditions, deep within limestone caves.
Researchers found racial disparities in pediatric appendicitis treatment tied to hospital type, with Hispanic and Asian children more likely to experience perforation at community hospitals. The study highlights the need for further research on prevention interventions to address these disparities.
Researchers found that people with mild cognitive impairment and Alzheimer's disease struggle to process semantic information, leading to broader implications for daily functioning. Semantic processing deficits may be slowed through training, and could contribute to decline in activities of daily living.
A groundbreaking air cleaning device developed by the University of Copenhagen has successfully removed Volatile Organic Compounds from industrial emissions. The invention uses natural processes to clean indoor air and remove pollutants, resulting in improved relations between businesses and their neighbors.
Tropical Depression Wukong is struggling to survive in the South China Sea, with NASA satellite data showing moderate rainfall near its center. The storm is moving west-southwest and is expected to dissipate over the next day or two, according to forecasters at the Joint Typhoon Warning Center.
Researchers have developed a framework for creating new materials by applying mathematical theorems to liquid crystal mediums. This approach could lead to improved energy efficiency in display devices, such as laptops and TVs.
New Geosphere articles explore Sonograms of Earth, a 1138-m-long drill core representing 20 million years of glacial history. The articles also examine alternative hypotheses for the origin of Grand Canyon and solve debates over Death Valley.
Researchers discovered that adding lovastatin to traditional antimalarial treatment decreases neuroinflammation and protects against cognitive impairment in a mouse model of cerebral malaria. Statins may be worthy of consideration in clinical trials for treating cerebral malaria.
The first genomic sequence of Chinese plum (Prunus mume) has been completed, providing a valuable resource for improving fruit trees. The genome sequence reveals important genetic information for understanding the evolution and diversity of Rosaceae family.
A Penn team has developed a new class of malaria drugs by mimicking a natural reaction with a synthesized molecule, inhibiting the calpain enzyme. The innovation uses an alpha-helical shape to block the enzyme's activity, offering a highly specific and potentially safer alternative.
The MBL physiology course fosters a culture of curiosity and innovation among students, leading to the generation of 23 research papers and 59 meeting abstracts. The course's unique approach combines cell biology and physical sciences, and encourages students to think beyond their comfort zones.
A Vanderbilt study predicts cuts in Medicare and Medicaid disproportionate share funds for hospitals serving low-income patients, even if Medicaid is not expanded. States that don
Garen Wintemute believes broader background checks and denials on gun purchases can reduce harm and ensure public safety. He cites research showing that individuals with a history of misdemeanor violent crime are nine times more likely to be arrested for violence later.
Researchers at Tufts University developed a novel method for fabricating collagen structures that maintain the protein's natural strength and fiber structure. The new technique, called bioskiving, creates scaffolds with tensile strength stronger than those made using common processing techniques.
Studies using new technology show that our ability to imitate facial expressions depends on learning through visual feedback. In two studies, researchers found that participants who could see their imitation attempts improved over time, while those relying solely on proprioception got worse.
A new study comparing neural responses of birds and humans to music suggests that both share a neural reward system, with females in the breeding state responding similarly to human music. Male birds also exhibit an amygdala response to discordant sounds.
The inaugural issue of Clinical Psychological Science (CPS) publishes diverse and boundary-crossing perspectives on topics such as targeted rejection, major depressive disorder, youth mentoring, and mind wandering. The journal aims to define a new way of studying clinical phenomena through innovative research.
The Johns Hopkins Bloomberg School will provide relief agencies and governments with technical assistance on using oral cholera vaccine. The DOVE program aims to detect outbreaks in remote areas and contain the disease, improving global efforts to combat cholera.
Researchers at Rush University Medical Center identified a chemokine known as monocyte chemoattractant protein-1 (MCP)-1 and its receptor, chemokine receptor 2 (CCR2), as central to the development of osteoarthritis pain. This finding could lead to new treatments for this debilitating condition.
Researchers develop thermodynamically rigorous analysis to parse free energy of polymodal voltage- and ligand-dependent ion channels. This new approach offers a model-independent way to study ion channel gating, useful for constraining future atomic-scale models and understanding disruptions caused by genetic mutations.
Researchers at the University of Exeter have developed a new genetic sequencing technology to identify novel mutations causing congenital hyperinsulinism. This breakthrough will enable clinicians to make more informed decisions about treatment, reducing the need for invasive procedures.
Researchers at UNC School of Medicine identified polycomb-like proteins as key regulators in stem cell development and cancer. The study found that these proteins interact with epigenetic signals to control gene expression, implications for both stem cell biology and cancer development.
Researchers have discovered two new species of Caribbean orchid belonging to the Laeliinae family. The new species, Encyclia navarroi and Tetramicra riparia, were found in Cuba's eastern and western zones respectively.
Three WHOI projects will investigate the complex interactions between marine microbes, nutrients, and their environments using advanced technologies and methods. The grants aim to improve understanding of microbial communities and their impact on ocean health and productivity.
A new study reveals how a 'transcription factor' called ELF5 causes aggressive breast cancer to develop, making it resistant to oestrogen therapies. Researchers found that manipulating ELF5 levels could be a potential treatment option for this type of breast cancer.
A team of researchers at the University of Pennsylvania School of Medicine has identified a powerful new weapon against malaria by mimicking a natural defense found in human blood platelets. They discovered that a synthetic molecule, PMX1207, targets and destroys the parasite's digestive vacuole, killing it without harming the host cell.
Researchers at McGill University have discovered AMPK's role in restricting cancer cell growth by regulating metabolism and preventing the use of sugar to fuel growth. AMPK, a tumour suppressor, can help control tumour development by targeting energy levels and promoting healthy cellular function.
Researchers found that stem cell protein Ell3 marks enhancers that regulate gene expression, priming them for future activation. This discovery has significant implications for understanding cancer and development.
Researchers have discovered a way to manipulate the hepatitis C RNA to block its hijacking of cell machinery, potentially leading to new treatments.
A study at Ben-Gurion University predicts course grades based on students' online and offline social connections. The researchers found that students with good social networks tend to excel academically and are more likely to pair with peers who share similar strengths.
Researchers identified the mechanism by which Staphylococcus aureus colonizes nasal passages, finding that Clumping factor B (ClfB) binds to skin protein loricrin with high affinity. This interaction is crucial for successful colonization and opens new avenues for developing therapeutic strategies.
Researchers at Arizona State University have fabricated an artificial protein and examined its effects on living cells, revealing a peculiar set of adaptations including filamentation, ATP depletion, and the formation of endoliposomes. These findings may lead to the development of novel therapeutic agents.
Researchers at Case Western Reserve University will study ways to integrate patients' strengths into assessment and treatment to improve outcomes. The project aims to provide patients with better-informed health decisions, leveraging strengths such as resilience and mindfulness.
A new study links vector-borne diseases to economic development across the globe, finding that these diseases have a substantial effect on income between tropical and temperate countries. The study's results suggest that infectious diseases can undermine economic growth similarly to crime or government corruption.
The Geological Society of America published a special series of invited papers to mark its 125th anniversary, including a revised geologic time scale. The articles cover various topics such as mammal fossils, sediment delivery rates, volcanic material provenance, and ecosystem changes.
A recent study published in PLOS Biology has discovered the role of ELF5 in aggressive breast cancer subtypes and its potential to overcome anti-estrogen therapies. The research suggests that manipulating ELF5 levels could lead to new treatment strategies for breast cancer patients.
Research published in PLOS ONE found that kids who perform acts of kindness are happier and find greater acceptance among their peers. Kind acts, such as giving someone lunch or visiting a pleasant place, increased children's well-being and improved their relationships with classmates.
Researchers at the University of Pennsylvania developed a non-invasive MRI-based algorithm to screen patients for Alzheimer's disease or frontotemporal lobar degeneration. The method, published in Neurology, accurately differentiated cases 75 percent of the time and showed comparable accuracy to lumbar puncture tests.
A team of scientists discovered that the ancient piranha relative Megapiranha paranensis had a bite force that could crush bone and pierce through thick shells, rivaling even the mighty T. rex. The study, published in Scientific Reports, used computer simulations to estimate the bite forces of living and extinct piranhas.
Researchers at Johns Hopkins Medicine have developed a novel approach to sorting out cancer-causing genetic mutations in cancer cells. By testing proteins produced by genes with random mutations, they created a catalog of mutants with cancer-promoting potential. This could lead to more personalized treatment strategies for patients.