A collection of articles investigates the impact of antiretroviral treatment on new HIV infections, exploring its potential epidemiological impact and affordability. The studies assess the utility of mathematical models and evaluate their consistency with real-world data.
Lauren Sciences LLC has received a grant from The Campbell Foundation to develop a V-Smart therapeutic for neuro-HIV. The treatment aims to deliver tenofovir across the blood brain barrier to treat viral reservoirs in the central nervous system.
The University of Minnesota has licensed its Clinical Decision Support technology to Omicron Health Systems, enabling improved coordination of patient care and research activities. The technology helps standardize medical records, facilitating communication and targeted treatments among clinicians and researchers.
LMU researchers have identified magnetosensory cells in trout that detect the Earth's magnetic field and convert it into nerve impulses. The cells sense the field through micrometer-sized inclusions of magnetic crystals, which are coupled to the cell membrane.
Astronomers discover that small dwarf galaxies in the Milky Way contain only a few stars and share the same birth date, indicating they were shut down by reionization. The relic galaxies provide evidence for a transitional phase in the early universe.
A landmark study reveals that police officers are at significantly higher risk for chronic disease, obesity, and suicide compared to the general population. The study found that shift work, stress, and lack of access to healthcare contribute to these risks.
Researchers at Michigan State University have developed a novel biofuel production process that produces energy more than 20 times higher than existing methods. The process, known as microbial electrolysis cells (MECs), uses bacteria to breakdown and ferment agricultural waste into ethanol.
Scientists from the University of Zurich identified a key role for the Sox10 gene in promoting melanoma development and proliferation. Suppressing this gene in mice inhibited cancer growth, offering new potential therapy avenues.
Researchers mapped ferroelectric structural distortions in individual nanocrystals using the world's most powerful transmission electron microscope. The study indicates that a monodomain ferroelectric state remains stable down to dimensions of less than 10 nanometers, and room-temperature polarization flipping was demonstrated down to ...
Scientists successfully grow nanorods of zinc oxide on a thin layer of polydiethylflourene, creating white LEDs that can be printed on paper or wallpaper for display purposes. This breakthrough method uses chemical methods and has the potential to enable mass production of flexible electronics.
Researchers are developing a new oral multiple sclerosis drug that targets the molecule miR-326, which stimulates the production of immune system mediators. The drug aims to inhibit miR-326 and block the production of Th17 cells, potentially offering a more convenient treatment option for patients.
A clinical trial found that Souvenaid improved verbal-memory performance in 40% of patients with mild Alzheimer's, while a control group showed deterioration. The nutrient cocktail boosts new synapse formation, potentially reversing cognitive decline.
Researchers found two genetic variations in chickens with potential to fight cancer and bacterial infections, offering new clues for disease treatment. The discovery is based on the examination of NK-lysin, an antibacterial substance that occurs naturally in animals.
A systematic review found that the level of evidence for emergency obstetric referral interventions is poor, making it difficult to determine their effectiveness. The design limitations of individual studies also hindered the assessment of referral interventions.
The ONR Rough Rhino system tracked over 600 vessels of interest during the recent AMLEP operation, culminating in 24 boardings by maritime security teams. The system provided a comprehensive maritime domain awareness picture for dark and light targets.
A University of Toronto study found that the type of relationship consumers form with brands influences their assessment of fairness. In exchange relationships, respectful treatment is more crucial in fair outcomes, while in communal relationships, it has less effect. Marketers must understand these dynamics to correct unfair outcomes.
A new nationwide study by UC Davis examines mortality rates and epidemiological aspects of stray-bullet shootings, finding that most victims were unaware of the events leading to their injuries. The study reveals that nearly one-third of victims were children and nearly half were female.
A new study estimates that contraceptive use prevents more than 272,000 maternal deaths from childbirth each year. The researchers found that satisfying the global unmet need for contraception could reduce maternal deaths by an additional 30%. Effective contraception also averts nearly 230 million unintended births annually.
Remote presence robots enhance critical care physician interactions with patients, leading to improved patient satisfaction. Most surveyed ICU physicians intend to continue using the technology, believing it improves patient care.
Researchers discovered a way to inhibit Taspase1 by 'gluing together' individual molecules, providing a promising approach for cancer treatment. The enzyme plays a critical role in the development of leukemias and solid malignancies, making it a key target for disease therapy.
NASA's GOES-15 satellite captured an image of three tropical systems chasing each other in the eastern Pacific Ocean, with Tropical Storm Daniel and Hurricane Emilia at the center. The system is expected to weaken to tropical depression status by July 11.
Forest soils lose more carbon under elevated CO2 levels, contrary to previous assumptions. The IU-led research reveals that microorganisms play a key role in this process.
Research reveals that copper from brake linings and mining operations impacts salmon's ability to detect predators via their sense of smell. This altered state makes them more susceptible to attack by predators.
The UK Space Agency has launched its Civil Space Strategy, aiming to capture 10% of the global space market by 2030. The strategy focuses on creating new opportunities for industry, bolstering the role of space in the UK's infrastructure, and furthering national space technology.
A University of Illinois researcher is testing a new model for conservation that involves raising awareness among private landowners about invasive species and providing strategies for moderate livestock grazing and controlled burns. The goal is to promote the growth of native wildlife habitats in the Grand River Grasslands, which has ...
The evolutionary block cipher outperforms known cryptosystems in resisting both linear and differential attacks by introducing evolving encryption algorithms. This design feature enhances the system's security and efficiency, making it a promising solution for modern cryptography.
A team of microbiologists at UMass Amherst has made an advance in understanding the replication of parasites like African sleeping sickness and chagas disease. By characterizing key proteins' organization, they discovered a novel mechanism that could lead to the development of new treatments.
Researchers at the University of Michigan have discovered a new single-gene cause of chronic kidney disease, which implicates DNA damage response signaling. The study found that mutations in Fanconi anemia-associated nuclease 1 (FAN1) lead to increased DNA damage and apoptosis in patients with CKD.
Research suggests that adding words related to health and weight on posters, menus, or recipe cards can stimulate healthy food choices among dieters and overweight individuals. This technique has great potential as an intervention to help weight control, as it is unobtrusive, easy to implement, and low in cost.
A recent study found a small but significant risk of Guillain-Barre syndrome following H1N1 vaccination, primarily in individuals over 50 years old. The risk was estimated to be approximately 2 cases per 1 million doses, with most cases occurring within 4 weeks of vaccination.
Researchers from Case Western Reserve University School of Medicine developed a mouse model that mimics the N48K mutation in Usher III, leading to understanding of how deafness occurs. This new model enables exploration of prospective therapeutics to rescue mutant protein localization and hearing.
Research finds that people at risk for early-onset Alzheimer's disease want to know their genetic profile, but struggle with the results. The study also reveals that the general population and those with a family history of late-onset AD tend to be motivated by fear and anxiety when considering genetic testing.
Researchers at Arizona State University improved microbial fuel cell efficiency by modifying cathode materials and adjusting pH levels. By enhancing hydroxide ion transport, they increased power densities and reduced losses in MFC performance.
Two studies found that infants exposed to the H1N1 vaccine in utero did not have a significantly increased risk of major birth defects, preterm birth, or fetal growth restriction. However, adults exposed to the vaccine were at a small increased risk of Guillain-Barre syndrome during the 4-8 weeks after vaccination.
Cloud top temperatures around Hurricane Emilia's eye were measured to be colder than -94F, indicating high-energy storms. NASA's Aqua and Terra satellites tracked the hurricane's rapid strengthening and weakening phases.
A study by Dr. Natalie Loxton found that individuals with high reward sensitivity experience increased pleasure and urge to eat after watching TV commercials featuring junk food. This suggests a link between reward sensitivity and overeating, particularly in response to appetitive cues.
A recent study found that African-American youths living in public housing communities are 2.3 times more likely to use tobacco than their peers. Early interventions, such as smoking cessation programs and addressing depressive symptoms, can help reverse positive attitudes towards tobacco use and reduce the risk of delinquent behaviors.
A new solar photovoltaic thermal (PVT) system has been developed by Queen's University researchers, generating both electricity and heat. The system uses amorphous silicon cells, which require less material, cost less to manufacture, and offer a higher return on investment.
The American Orthopaedic Society for Sports Medicine (AOSSM) recognizes innovative research in orthopaedic sports medicine through various awards, including the Young Investigators Grants, Clinical Research Outcome Grant, Innovative Outcomes Assessment Grant, and O'Donoghue Sports Injury Research Award. The grants provide funding for s...
Researchers found that rats consuming all their sugar solution in the inactive period gained more weight than those consuming it during the active period, despite similar caloric intake. This study suggests that the timing of sugar consumption can significantly affect body weight gain.
Research presented at the Society for the Study of Ingestive Behavior Annual Meeting finds that high-fat diets increase active-period sleep and sleep fragmentation in rats. Poor sleep quality is associated with reduced orexin sensitivity, a key brain chemical involved in regulating sleep and wake states.
Scientists have discovered a new plant species in Scotland that has overcome infertility and formed a new hybrid. This rare example reveals the process of polyploidization, allowing the plant to restore fertility and thrive in the wild.
A new study finds that rheumatoid arthritis (RA) patients receive regular cancer screenings, including breast, cervical, and colon cancer tests, at similar rates to the general population. The study's results challenge previous research suggesting RA patients receive fewer cancer screenings.
The Global Alliance of Continuous Plankton Recorder Surveys has been formed to standardize methods and share data on plankton biodiversity globally. The initiative aims to provide a comprehensive perspective on ocean basin scales, crucial for understanding climate change impacts.
Researchers discovered that tumor cells release chemokine CCL2, which docks onto endothelial cells and activates the CCR2 receptor, making them permeable. This pathway enables tumor cells to migrate and metastasize.
Research established RNA Polymerase I (Pol I) activity as essential for cancer cell survival, and its inhibition with CX-5461 selectively activates p53 to kill tumors. The drug was shown to be 300 times more potent than non-genotoxic p53 activators.
A new study suggests that government initiatives to strengthen low-income marriages should focus on addressing specific problems rather than promoting the institution of marriage. Low-income respondents reported similar romantic standards and experiences as high-income couples, despite facing unique economic and social issues.
A case study on implementing the BasicNeeds model of mental health and development in Nepal found that user empowerment and community development are key to success. The model works in partnership with governments to provide essential services where mental health has not been a priority, leading to improved outcomes for users.
Research in rats and humans found that multiple pieces of food elicit greater satiation than a single piece, with increased portion sizes leading to increased intake. Cutting food into smaller pieces can make it more satiating, benefiting dieters seeking portion control.
A study found that liver stiffness measured by transient elastography is an independent predictor of liver failure, hepatocellular carcinoma, and mortality in cirrhotic patients coinfected with HIV/HCV. The measurement also predicts potential recovery and survival in patients with cirrhosis.
University of Iowa scientists have created a technique to estimate cloud properties using remote sensing observations from satellites, correcting predictions of particle concentrations. This new method is expected to find immediate application in various activities, including air quality forecasting and climate projections.
A large prospective study found that cardiac surgery has become significantly safer, even for high-risk patients, with complication rates at 5%, compared to previously reported 10%. The study also failed to show acadesine, a protective drug, reduced complications.
A study published in JAMA found that administering the regulating agent acadesine before CABG surgery did not reduce all-cause mortality or need for mechanical support. The trial included 2,986 patients and found no significant difference between those who received acadesine and those on placebo.
Archaeologists and engineers at the University of Southampton are using advanced X-ray imaging technology to study Roman coins. The technique allows for non-invasive examination and identification of coins, which can also be used to read inscriptions and depict emperors' faces.
Research suggests that sleep behavior affects body weight control and that sleep loss has ramifications for how many calories we consume and burn off through physical activity. Sleep deprivation increases hunger and reduces physical activity, leading to weight gain and increased risk of obesity and type 2 diabetes.
The tissue engineering and stem cell industries have experienced significant growth, with over half of companies generating revenue, up from 21% four years ago. Commercial products and services are driving the increase, with $3.5 billion in sales revenues and industry spending approaching $3.6 billion.
Kendall L. Carder has been recognized with the Jerlov Award for his groundbreaking research on in situ optical measurements, underwater imaging systems, and ocean color remote sensing. His contributions have significantly advanced our understanding of light in the ocean.
A new algorithm developed by MIT and Harvard researchers drastically reduces the time it takes to find a particular gene sequence in a database of genomes. The more genomes it's searching, the greater the speedup it affords.
23andMe's acquisition of CureTogether expands its capacity for people-powered research and community-driven projects. The combined platforms will facilitate the sharing of genetic and phenotypic data to accelerate research discoveries.
A meta-analysis of self-determination theory research in health contexts found that respect for patients' autonomy is positively related to feelings of autonomy, competence, and relatedness. Satisfaction of psychological needs was also linked to improved patient well-being, including both mental and physical health.