The Open Data Institute (ODI) will incubate and mentor new businesses that exploit open data, aiming to drive economic growth. The institute will also host 'appathons' or 'hackathons' to develop new use cases for open data.
Researchers have found that cancer cells may require simpler genetic mutations than previously thought to grow and proliferate. The most common hemizygous deletions in cancer involve tumor suppressing genes called STOP genes, which are haploinsufficient, meaning they depend on two copies to function normally.
Researchers at Cold Spring Harbor Laboratory have solved the atomic structure of a human protein bound to a microRNA guide, revealing its biological mechanism of action. The discovery could aid in understanding gene function and advancing RNAi as a therapeutic strategy.
A new invasive species of sea crab, Dyspanopeus sayi, has established itself in the Western Mediterranean Coast, particularly in the Ebro Delta. The crabs are well-established and reproducing in the area without problems, with both sexes captured along with ovigerous females carrying eggs.
A research team at Bielefeld University is studying how female locusts prefer males with the most powerful swellings on their front legs. The study aims to understand the evolution of sexual ornaments and their role in mate selection, which may be linked to an animal's health.
Researchers at the European Molecular Biology Laboratory have discovered a 'transformer' protein that allows cells to create vesicles of different shapes and sizes by changing the shape of individual building blocks. This breakthrough provides new insights into the structure and function of COPI protein-coated vesicles.
Researchers found that a specific gene, CCR2, associated with immune activity is linked to memory and cognitive function in people. This discovery could lead to new approaches to slowing or preventing Alzheimer's disease.
Typhoon Sanvu is affecting Iwo To and Chichi Jima with high winds, rough seas, and heavy rainfall. The storm is expected to weaken due to cooler ocean temperatures and wind shear by the end of the weekend.
Researchers found that Skp2 E3 ligase promotes Herceptin resistance in breast cancer by activating the Akt kinase, which also regulates glucose metabolism. The study suggests that blocking Skp2 could inhibit glycolysis and provide a new approach to cancer treatment.
Wildlife researchers at UMass Amherst have captured photographs of the rare Sumatran striped rabbit, which may now be found only in two remote national parks on the Indonesian island. The discovery highlights the importance of protecting these areas from encroachment and development, which threaten the survival of the species.
Researchers developed a mathematical model predicting the final size and shape of platelets, which form blood clots. The study provides insights into the forces inside cells that turn into platelets, shedding light on a longstanding puzzle in platelet formation.
Scientists at Oregon State University have discovered that curcumin can increase levels of a protein that helps prevent infection, highlighting its potential as an alternative to vitamin D. The study found curcumin causes a modest but measurable increase in cathelicidin antimicrobial peptide (CAMP) levels.
Hurricane Bud is expected to make a quick landfall in western Mexico before turning back to sea, bringing heavy rainfall and severe flooding to the region. The storm's slow movement may result in life-threatening flash floods and mudslides as it moves over Mexico's rugged coastal terrain.
Researchers at the University of Bonn have visualized the transport of messenger RNA from the cell nucleus to the cytoplasm using a highly sensitive light microscope. The study reveals that the process involves brief collisions with the nuclear membrane and quality control checks, resulting in only about every fourth successful export.
Dr. David Feola, a University of Kentucky College of Pharmacy faculty member, has received a five-year, $1.8 million grant from the National Institutes of Health to investigate immune responses in the lungs that may lead to medical treatments for cystic fibrosis and other chronic pulmonary inflammatory conditions.
A team of researchers at Baylor College of Medicine has identified a distal axonal cytoskeleton as the boundary that ensures AnkyrinG clusters properly. The findings suggest that AnkyrinG cannot move beyond this boundary, resulting in proper formation of the axon initial segment and subsequent neural function.
A Scripps-led study reveals that the nuisance seaweed Leptolyngbya crossbyana produces honaucins with potent anti-inflammation and bacteria-controlling properties. These compounds could one day treat chronic inflammatory conditions, bacterial infections, acne, and other skin conditions.
A new project aims to increase hearing aid use by providing easy-to-use video tutorials that address common barriers to adoption. The tutorials offer practical tips, animations, and real-life experiences from users to support patients in making the most of their devices.
The University of Louisville has received a $6.3 million grant to develop technology to help paralyzed people regain movement in their limbs, with the goal of improving quality of life. Researchers aim to advance research and treatment options for individuals with spinal cord injuries.
Researchers identified PERK as a crucial protein for maintaining behavioral flexibility, allowing us to adjust behaviors in response to changing circumstances. The study's findings have implications for addressing neurological disorders such as autism and schizophrenia.
A Category Tree system would categorize products based on tested human studies and health benefits, forcing companies to conduct research or change product labels. This system aims to improve transparency and facilitate further research in North America and Europe.
A study by University of Notre Dame biologist Beth Archie and colleagues found that high-ranking male baboons recover more quickly from injuries and are less likely to become ill than other males. Social status is a better predictor of wound-healing than age, highlighting the complex interplay between social context, physiology, and im...
Scientists have directly measured the Yarkovsky effect on asteroid 1999 RQ36, a subtle force causing it to drift from its gravity-ruled orbit. The measurements show the asteroid has deviated by roughly 100 miles over 12 years, revealing its low density and making it an ideal target for the OSIRIS-REx mission.
Researchers found that the human olfactory bulb, a brain structure processing sensory input from the nose, lacks new neuron generation like other mammals. This discovery may explain why humans have a poorer sense of smell compared to other animals.
Researchers emphasize the need for standard bone age measurement to interpret growth status and improve treatment outcomes for children with Crohn's disease. Up to 80% of patients exhibit compromised growth, and bone age is crucial for predicting remaining growth potential and guiding therapeutic decisions.
Researchers identified a single gene AUF1 controlling inflammation, aging and cancer. The study found that deleting the gene led to accelerated aging.
Obese patients have an increased risk of developing kidney damage, or acute kidney injury, after heart surgery. Oxidative stress associated with obesity plays a role in this increased risk. Acute kidney injury affects 5% to 30% of heart surgery patients.
A new study by the Max Planck Florida Institute found that changes in sensory experience can cause massive rewiring of the brain's connections, even in older adults. This rewiring involves fibers supplying the primary input to the cerebral cortex, a key area for sensory perception and cognition.
The International Osteoporosis Foundation reports a significant increase in osteoporosis-related fractures and diagnoses in Latin America, driven by the region's aging population. The projected rise in fragility fractures poses a substantial socio-economic burden on healthcare systems.
Researchers at the University of Bristol used forensic-style chemical analysis to directly link seismic observations to crystal growth in a magma chamber. The study found correlations between peak crystal growth and increased seismicity prior to the 1980 Mount St. Helens eruption.
Researchers at Berkeley Lab observed nanoparticles forming winding polycrystalline chains that align and attach end-to-end to form nanorods with controlled length-to-thickness ratios. This process suggests a new understanding of how nano-sized particles assemble into hierarchical structures.
A study published in the Journal of Clinical Oncology found that childhood cancer survivors experience increased anxiety, depression, and depressive symptoms due to persistent hair loss and disfigurement. The study's findings highlight the long-term impact of childhood cancer treatment on quality of life.
A study found that marine reserves on Australia's Great Barrier Reef produce approximately half of all juvenile recruitment to both reserve and fished reefs. The reserves, which account for just 28% of the local reef area, help sustain valuable fisheries.
Scientists at NASA's Goddard Space Flight Center are developing an infinitely smaller segmented mirror, called the Multiple Mirror Array (MMA), that will revolutionize space-based telescopes. The MMA promises to detect, image, and characterize planets beyond our solar system from a high-altitude balloon.
Researchers at Berkeley Lab directly observed the critical step of oriented attachment in nanocrystal growth, enabling a better understanding of forces driving this phenomenon. This breakthrough has potential applications in synthesizing new biomimetic materials and improving environmental restoration efforts.
A recent study has identified more than 40 genetic regions influencing fertility in Hutterite men, which may shed light on unexplained cases of male infertility. The research also found nine genetic regions impacting sperm quality in non-Hutterites.
A recent clinical trial found that gene therapy can insert the correct ADA gene into patient bone marrow cells, leading to a good response. Defects in B cell tolerance are also corrected after gene therapy, supporting its use as an effective treatment option for ADA-deficient severe combined immunodeficiency patients.
Researchers identified glycerophosphate oxidase as a critical protein for bacterial progression to the brain. A vaccine against this protein protected mice from invasive pneumococcal disease, offering a new approach to immunizing against S. pneumoniae.
Scientists have identified the Mitochondrial Pyruvate Carrier (MPC), a universal carrier that transports pyruvate into mitochondria. This discovery could lead to a better understanding of how cancer cells produce energy and potentially develop new treatments.
A new study from Michigan State University reveals that exercising with a moderately capable virtual partner can significantly boost motivation, with women cycling twice as long when working with a partner. The results suggest the gains observed over six hour-long sessions could be sustained on a longer-term program of exercise.
Research identifies pivotal role of proteins in cellular and disease processes, shedding light on neuromuscular disorder and cancer connections. The study found that impaired Mpc1 and Mpc2 lead to deadly health problems, including the neuromuscular disorder.
A study published in EPJ Data Science found that words with positive emotional content are more frequently used in online communication, enhancing social relations and facilitating interaction. This positive bias is linked to the use of less informative words for emotional expression.
A new study found that warmer summers have allowed the Brown Argus butterfly to shift its diet to wild Geranium plants, enabling it to expand its range in Britain at a rapid rate. Over 20 years, the butterfly has spread northwards by 79km, becoming common in southern England.
Scientists with the OSIRIS-REx mission have measured the orbit of asteroid 1999 RQ36 with great accuracy, directly determining the drift resulting from the Yarkovsky effect. The asteroid has deviated from its gravity-ruled orbit by roughly 100 miles in the last 12 years due to this subtle force.
A study by Concordia University found that business students who evaluate their peers regularly improve in evaluating others. This leads to more effective management skills. The research developed a standardized online peer evaluation system, which can be incorporated into university-wide programs.
Microglia, the brain's emergency workers, use a long-lasting glutamate-driven calcium wave to detect injuries, allowing them to trace the signal backwards until they reach the site of damage. This discovery could lead to new treatments for conditions such as Alzheimer's and Parkinson's diseases.
Researchers at Brigham and Women's Hospital have identified a microRNA called miR-181b that can reduce the inflammatory response responsible for diseases like sepsis. The findings suggest that higher levels of miR-181b may be protective against sepsis and other inflammatory diseases.
Scientists at Georgia Institute of Technology used acoustic fields to enhance heat transfer, removing vapor bubbles and suppressing insulating film formation. This led to improved boiling efficiency.
A new study by Carnegie's Andrew Steele provides strong evidence that Martian organic carbon originates from the planet itself, not Earth or other meteorites. The findings reveal insights into Mars' volcanic history and suggest the presence of organic chemistry throughout its history.
Researchers discovered an anti-psychotic drug, thioridazine, that selectively targets and exhausts cancer stem cells, leading to improved survival rates in leukemia patients. The compound works by encouraging cancer stem cells to differentiate into less threatening cell types.
A recent study suggests that peritonitis, a common infection in dialysis patients on peritoneal dialysis, may be linked to premature death. Researchers found that patients were more likely to develop peritonitis during the final month before their death, and even six times more so during the 30 days prior to their death.
The UK's world-leading researchers in synthetic biology will establish platform technology with a new grant of almost £5 million. The platform technology will be based on an information system – SynBIS – which uses a web-based environment, hosting BioCAD and modelling tools for the field.
A study by UC San Diego biologists found that a small dose of imidacloprid, a commonly used crop pesticide, makes honey bees more selective and less willing to feed on low-sugar nectar. This can lead to reduced food stores and communication among the colony.
Researchers at Aalto University found that strong emotions sync brain activity in frontal and midline regions for unpleasant feelings and vision, attention, and sense of touch networks for highly arousing events. This synchronization facilitates understanding others' intentions and actions.
New research published in Hepatology found that moderate exercise does not improve lipoprotein concentrations in obese patients with non-alcoholic fatty liver disease. While exercise reduced intrahepatic triglyceride content, it did not change liver lipoprotein levels or body weight.
Researchers at McMaster University have discovered a drug, thioridazine, that kills cancer stem cells in humans while avoiding toxic side effects of conventional treatments. The study holds promise for new strategies and discovery pipelines for developing anticancer drugs.
A team of American researchers has created an array of 25,000 individual invisibility cloaks that can slow down or stop light, creating a trapped rainbow. This technology enables 'spectroscopy on-a-chip' for detailed analysis of biological materials.
Scientists have developed a method to analyze noisy X-ray data, revealing details of molecular structure previously discarded due to low signal quality. This breakthrough could lead to more accurate models and improved understanding in biology, medical diagnostics, nanotechnology and other fields.
Researchers at Georgia State University's College of Education have been awarded a $10 million grant to create the first national research center focused on improving reading for children who are deaf or hard of hearing. The goal is to identify child and instructional factors that affect reading growth and develop individualized interv...
Researchers at MIT have developed a device that delivers a variety of drugs through the skin without using needles, potentially improving patient compliance and reducing accidental needle-stick injuries. The device can be programmed to deliver different doses to varying depths, addressing limitations of existing jet-injection systems.