A study analyzing data from 28 US children's hospitals found a significant increase in resource use among hospitalized children with chronic conditions. The study reveals that children with complex, lifelong illnesses accounted for the largest percentage of hospital charges and days.
SourceJAMA Network·JournalArchives of Pediatrics and Adolescent Medicine·DateDec 24, 2012
A new meta-analysis of 10 studies involving over 203,000 patients with anemia and heart attacks found that liberal blood transfusions increased the risk of death by 12% and had twice the odds of another heart attack. The study calls for rigorous randomized trials to determine when transfusions are appropriate.
SourceBrown University·JournalArchives of Internal Medicine·DateDec 24, 2012
A study by Brown University biologists found that the PACMAD clade of grasses developed an anatomical predisposition to C4 photosynthesis due to evolutionary pressures. The clade's bundle sheath cells became larger, facilitating more efficient CO2 transfer when temperatures rise or plants become stressed.
SourceBrown University·JournalProceedings of the National Academy of Sciences·DateDec 24, 2012
A new study by Washington University School of Medicine found that children suspected of having appendicitis are more likely to receive ultrasound scans instead of CT scans at St. Louis Children's Hospital, reducing radiation exposure. Researchers aim to find ways to reduce CT imaging use without compromising patient care.
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A recent Mount Sinai survey reveals that nearly 1 in 3 children with food allergies are bullied, leading to increased stress levels and lower quality of life. The study highlights the importance of parents, school personnel, and physicians being aware of bullying in this population.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalPEDIATRICS·DateDec 24, 2012
A recent study found that Amazon deforestation results in a significant loss of microbial diversity, leading to reduced ecosystem resilience. The research team discovered that the conversion of rainforest to agricultural pastures causes a homogenization of bacterial communities, resulting in a net loss of diversity.
SourceUniversity of Massachusetts Amherst·JournalProceedings of the National Academy of Sciences·DateDec 24, 2012
A recent study found that deforestation in the Amazon rainforest leads to a net loss of diversity among microbial organisms, which are crucial for ecosystem function. The research revealed biotic homogenization and reduced genetic variation in bacteria across converted forests, compromising ecosystem resilience.
SourceUniversity of Texas at Arlington·JournalProceedings of the National Academy of Sciences·DateDec 24, 2012
University of Massachusetts Amherst mathematician Robert Kusner explains the observed
SourceUniversity of Massachusetts Amherst·JournalNature·DateDec 24, 2012
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Researchers found that the environment transitioned rapidly between a closed woodland and an open grassland, triggering evolutionary changes. The team used lake sediments and biomarkers to reconstruct the types of vegetation present, revealing a correlation between environmental changes and planetary movement.
SourcePenn State·JournalProceedings of the National Academy of Sciences·DateDec 24, 2012
Researchers have identified key proteins involved in loading a vital protein into the centromere, a critical region for cell division. Disruption of this process can lead to abnormal numbers of chromosomes, common in 90% of cancer cases.
SourceNew York University·JournalProceedings of the National Academy of Sciences·DateDec 24, 2012
A meta-analysis of 10 studies suggests that blood transfusions are associated with increased all-cause mortality in patients with myocardial infarction. The analysis found a weighted absolute risk increase of 12% and a higher risk for subsequent myocardial infarction, highlighting the need for further research.
SourceJAMA Network·JournalArchives of Internal Medicine·DateDec 24, 2012
A study published in Neurology found that people with MS relapses had faster retinal thinning than those without relapses. The study also showed that participants with worsening disability experienced increased retinal thinning.
SourceAmerican Academy of Neurology·JournalNeurology·DateDec 24, 2012
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A study published in PNAS reveals that inflammation enhances the activity of enzyme ADAR1, leading to increased self-renewal and therapeutic resistance in cancer stem cells. Targeting this pathway with a small molecule inhibitor may help prevent relapse and progression of chronic myeloid leukemia.
SourceUniversity of California - San Diego·JournalProceedings of the National Academy of Sciences·DateDec 24, 2012
An analysis of nationally representative survey data found significant improvement in the delivery of underused care, including better use of antithrombotic therapy and aspirin for atrial fibrillation. However, the study also found limited changes in reducing inappropriate care, such as overuse of antibiotics for asthma exacerbations.
SourceJAMA Network·JournalArchives of Internal Medicine·DateDec 24, 2012
Research suggests that reducing pavement and increasing natural habitat can improve nesting opportunities for wild bees. Bees will also forage further away from their home nest if the surrounding landscape is less heterogeneous, seeking out species-rich patches.
SourceUniversity of Texas at Austin·JournalProceedings of the National Academy of Sciences·DateDec 24, 2012
Researchers found an association between elevated levels of C-reactive protein and increased risk of psychological distress and depression in a large Danish population. Elevated CRP levels were also linked to higher rates of antidepressant use and hospitalization with depression.
SourceJAMA Network·JournalArchives of General Psychiatry·DateDec 24, 2012
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