Dabrafenib, a BRAF inhibitor, demonstrates substantial tumor shrinkage in patients with brain metastases from melanoma. The study also reveals potential for the treatment to prolong survival beyond 12 months.
Researchers from the University of Southampton have developed a groundbreaking study to investigate the experiences and needs of people after primary treatment of colorectal cancer. The CREW study aims to inform healthcare providers about what helps or hinders rapid and effective recovery, with over 1,000 patients recruited.
Researchers at the University of Strathclyde and Stanford University have developed a prosthetic retina that can restore sight to patients with age-related macular degeneration. The device uses video goggles to deliver energy and images directly to the eye, eliminating the need for complex surgery.
Researchers are investigating whether chickens' vocalizations can provide clues to their health and comfort. The study aims to identify specific vocalization features that can be used to detect stress and optimize living conditions.
A modified version of Google's PageRank algorithm is used to rank proteins by their genetic relevance to pancreatic cancer progression. Seven proteins were found that can help assess tumor aggressiveness and guide treatment decisions.
Researchers unveiled an inexact computer chip that allows for occasional errors, boosting performance by at least 15 times. The design improves power and resource efficiency by pruning sections of digital circuits and using confined voltage scaling.
SomaLogic and NEC announce the release of SomaSuite, a professional software tool that simplifies the analysis of proteomic data generated by SomaLogic's SOMAscan assay technology. The tool enables researchers to quickly discover significant protein expression changes in their biological samples.
Scientists at Queen Mary University of London used zebrafish to study psychiatric disorders, finding they can modify their behaviour in response to changing conditions. The research suggests zebrafish may be useful in studying the cause and prognosis of disorders related to impulse control.
Researchers developed a method to induce transient ischemia during non-surgical interventional cardiac procedures, boosting adenovector gene transfection by over 100 fold. Cardium Therapeutics' Generx product candidate is being tested in a 100-patient Phase 3 trial for patients with myocardial ischemia and stable angina.
The American Society of Clinical Oncology (ASCO) has released five new studies at its upcoming annual meeting, including those on precision medicine and cancer's genetic weak spots. These studies demonstrate improvements in treatment for aggressive cancers and provide valuable tools to lessen the side effects of cancer treatment.
Two Johns Hopkins psychiatrists argue that the Diagnostic and Statistical Manual of Mental Disorders (DSM) needs radical change due to its current 'field guide' form, which provides checklists of symptoms but lacks underlying causes. The manual's limitations make it difficult for clinicians to direct treatment or investigate disorders.
Researchers found a strong association between early drug and alcohol use and lower levels of educational attainment. The study of over 6,000 male twins found that those who started drinking or using drugs before age 14 were less likely to finish college.
Scientists at Linköping University have developed a method to precisely control the threshold voltage of plastic transistors, a crucial property for their use in logic circuits. By modifying the gate electrode material, they were able to reduce the threshold voltage by up to 0.9V.
At EuroPCR 2012, expert panel discussions highlighted the potential for interventional cardiologists to support stroke patients with mechanical thrombectomy. Keynote speakers emphasized the need for education and training in interventional neuroradiology to ensure timely care for these patients.
Researchers are working on a space-based solar power system that can beam energy back to Earth through microwaves or lasers, providing a constant delivery of solar energy. The project aims to target remote areas difficult to reach by traditional means, such as disaster zones or outlying regions.
Researchers at UCLA have mapped the damaged connections in Phineas Gage's brain, revealing widespread damage to white matter pathways. The study, published in PLoS ONE, suggests that the disruption of these connections had a significant impact on Gage's personality and behavior.
A study by Elif Izberk-Bilgin explores how Muslim consumers in Turkey perceive global brands as 'infidels' due to sociopolitical dynamics. Consumers engage in boycotts to moralize the market and promote products reflecting their values, such as gender-segregated resorts.
Researchers have developed a new series of drugs that target the fox tapeworm, which causes rare but life-threatening disease in humans. The drugs, derived from anti-cancer agents, show potential in killing the parasite and treating the disease.
A GPS device provides ten data points per second, allowing for accurate evaluation of soccer players' acceleration, speed, distance covered, and workload indicators. The study found that midfielders have the highest number of accelerations and high-intensity movements during sprints.
A recent study from Fox Chase Cancer Center found that nearly half of the research presented at ASCO's annual meeting came from researchers with industry ties. The study suggests a growing dependence on industry funding for cancer research, highlighting the need to investigate potential conflicts of interest.
A collaborative study is exploring the proteome of triple negative breast cancers to identify new drug therapies and diagnostic tools. The researchers aim to understand how cancer cells operate and find proteins that could suggest treatment options.
A meta-analysis confirms statins reduce major vascular events by 21% in those with low risk of vascular disease. Statin therapy outweighs known side effects, suggesting current guidelines may need revision.
A new University of Miami study reveals that one in three children who have an older sibling with an Autism Spectrum Disorder (ASD) exhibit higher levels of autism-related behaviors or lower levels of developmental progress. Typically developing siblings may face subtle forms of ASD-related problems, such as lower back-and-forth play a...
A McLean Hospital study found that an herbal extract from the Chinese herb kudzu significantly reduces drinking and slows the pace of consumption. The study's lead author suggests that puerarin, a key component of the kudzu root, may be useful in treating alcoholism and curbing binge drinking.
A new study finds that girl child marriage rates have declined in some South Asian countries, including India, Nepal, and Pakistan, but not among older girls. The rate of marriages among girls under 14 has decreased significantly, while those between 16-17 years old show little change.
Researchers have developed a novel microscopy method to visualize cell structures in living fish larvae, resolving structures to 145 nm in the plane and 400 nm in-between. The technique allows for real-time observation of cell motion and development of vertebrates on the cellular level.
A paralyzed woman was able to sip from a drink on her own for the first time in nearly 15 years using a thought-controlled robotic arm. The BrainGate neural interface system, which records brain signals and turns them into digital commands, showed significant promise in clinical trials.
A new study published in Annals of Behavioral Medicine found that virtual exercise partners can significantly improve motivation and performance. Women who exercised with a more capable virtual partner cycled an average of two minutes longer than those who worked out alone, and reported no decline in motivation to exercise.
The FAME II trial demonstrates that targeting treatment to patients with ischemia significantly reduces the need for revascularisation. Patients without ischemia can be successfully managed using optimal medical treatment alone.
Scientists have created a new, inexpensive paper-based urine test to monitor glucose levels in areas with limited healthcare access. The device detects glucose levels using a simple enzyme reaction and can be built quickly, making it an ideal solution for rural India and other developing countries.
A phase II clinical trial found that abiraterone acetate, a hormone-depleting drug, can nearly eliminate or eliminate tumors in patients with aggressive cancers isolated to the prostate gland. The study showed promising results, encouraging further research into new treatments for high-risk prostate cancer.
Researchers at Brown University have made significant advances in brain-computer interfaces, allowing people with paralysis to control robotic arms in three-dimensional space. Participants were able to perform tasks such as reaching for foam targets, picking up objects, and even serving themselves coffee using only their brain signals.
Researchers have discovered compartmentalized neural activity in nematode neurons, which enables movement and encodes body position. This finding has significant implications for understanding neurological disorders like schizophrenia and developing potential treatments.
Biologists at UC San Diego have engineered algae to produce potential candidates for a malaria vaccine. The use of algae can lead to a cheaper and more accessible vaccine, as it can be grown in ponds or bathtubs anywhere in the world.
Taiwanese doctors use gene transfer to treat children with a rare neurological disease, restoring movement and improving cognitive development. The treatment has implications for Parkinson's disease and other neurodegenerative disorders.
Suicide rates among psychiatric in-patients have fallen by 29-31% between 1997 and 2008, according to a new study. Young patients and those with schizophrenia saw the largest declines. However, the risk of suicide for recently discharged patients may have increased over the same period.
Researchers from Japan and Karlsruhe have successfully used a synthetic photoreceptor to stimulate plant growth and development, regardless of exposure to light. This breakthrough could lead to improved agricultural practices and more efficient biomass production.
Researchers have found evidence of chronic traumatic encephalopathy (CTE) in brain tissue from blast-exposed military service personnel. The study discovered that exposure to a single blast equivalent to an IED results in CTE and long-term brain impairments, with the blast wind leading to traumatic brain injury.
A new study found that specific planning is less effective for achieving multiple goals due to increased obstacles and constraints. However, people who thought others had more goals than they did were more likely to benefit from planning and see their own goals as manageable.
A new treatment regimen, accelerated MVAC, has been shown to provide comparable benefits to standard chemotherapy without the same toxicity. This accelerated schedule of six weeks has improved response rates and tolerability for patients with muscle-invasive bladder cancer.
Researchers developed a model to study the behavior of cellular tissues, finding that they can split into disjointed patches when subjected to unfavorable substrates. This phenomenon, known as dewetting, is governed by the cells' sensitivity to substrate stiffness.
Researchers at the US Army Research Laboratory developed a novel processing technology that enabled commercial production of advanced Soldier head protection. The new helmets offer improved weight reduction and increased durability, with some models already fielded to Special Operations Forces.
Scientists at NYU School of Medicine identified a pathway that, if deactivated, may help slow the development of multiple myeloma. By targeting this pathway's cellular transcription process, researchers hope to find an effective treatment for the disease.
Researchers at Memorial Sloan Kettering Cancer Center have identified three genetic targets in approximately 50% of patients with squamous cell carcinomas. This breakthrough enables personalized treatment for a previously untreatable type of lung cancer.
Researchers at Lawrence Livermore National Laboratory have observed a 40 femtosecond ultrafast transition of graphite into two different states of matter, including solid to liquid and plasma. This discovery provides new insights into the behavior of matter irradiated by intense hard X-rays.
A new study in the Journal of Consumer Research found that minor language variations can affect consumers' attitudes towards brands. Consumers tend to feel closer to their bank than insurance company, and using 'we' versus 'you and [the brand]' can impact their perceptions.
A Vanderbilt University study found that azithromycin carries a significant increased risk of cardiovascular death, especially among those with high-risk factors. The researchers compared over 348,000 prescriptions of azithromycin to millions of similar records from patients not treated with antibiotics.
Researchers found that consumers choose brands to identify with their in-group but differentiate by selecting unique features, such as colors or styles. This balance between assimilation and differentiation is key to understanding consumer behavior.
AEMASE is a cognitive software application that updates its knowledge of experts' performance in real-time, automatically evaluating student performance and reducing overall training costs. The system will be used to train Navy personnel on various aircraft, including the H-60 helicopter and E-2C Hawkeye aircraft.
Researchers have isolated a gene related to autism, schizophrenia, and obesity in zebrafish, which may also contribute to human conditions. The KCTD13 gene regulates brain cell growth and is associated with head size at birth.
A new study has found evidence of chronic traumatic encephalopathy (CTE) in brain tissue from blast-exposed military service personnel. Exposure to a single blast equivalent to an IED results in CTE and long-term brain impairments, similar to those seen in athletes with repetitive concussion injuries.
A study of over 800 sets of twins found that genetics had a greater impact on forming key traits such as self-control, decision-making, and sociability than previously thought. The results suggest that genetically influenced characteristics may be the key to a person's success in life.
Researchers at the University of Bristol identified a simple yet crucial neural pathway in Xenopus frog tadpoles that initiates swimming. This discovery sheds light on how locomotion starts and may lead to new treatments for movement disorders like Parkinson's disease.
Scientists sequenced the Heliconius butterfly genome to understand wing pattern diversity, finding that different species copy each other's patterns by exchanging genes. This process allows hybrids to gain useful genes for adapting to changing conditions and survive.
The American Chemical Society reports a boom in research on ingredients for 'enhanced cosmetics,' with major companies investing in encapsulation technology to improve appearance. New approaches include microcapsules, water droplets coated in silica, and insulin sugar delivery systems.
A new study suggests that repeated head impacts in college athletes participating in contact sports can worsen their ability to acquire new information. The research found that 22% of contact sport athletes performed worse than expected on a test of new learning, compared to 4% of non-contact sport athletes.
Researchers have discovered a combination of lapatinib and cetuximab to be effective against cancers that have developed resistance to traditional therapies. In the clinical trial, two out of nine patients showed a partial response to the treatment.
Researchers found that some baby galaxies from over 12 billion years ago had a high content of heavier elements, similar to our Sun. This suggests potential for planet formation and life in the early Universe. The study used quasars as light sources to analyze the spectral lines and measure the amount of elements.
Researchers at Hebrew University developed a method for training blind persons to use sensory substitution devices. Participants were able to read letters and words with sizes smaller than the international standard for blindness.
Robert F. Ozols, a leading expert in ovarian cancer research, will be honored with the American Society of Clinical Oncology's 2012 Distinguished Achievement Award. He made significant contributions to advancing chemotherapy research and overcoming drug resistance.