Researchers found that allogeneic hematopoietic stem cell transplantation with mesenchymal stem cells from third-party donors improved poor graft function in five patients with acute GVHD and two with chronic GVHD. The treatment also showed promise in reducing morbidity and mortality.
A longitudinal cohort study of 1,310 women found that even three years after being declared free of cancer, women who had a false-positive result consistently reported greater negative psychosocial consequences compared to women with normal test findings. Researchers propose annual blood pressure screening instead of checking at every ...
A new study published in Clinical Psychological Science found that adults suffering from complicated grief retain their ability to recall specific memories of their past when those events involve the deceased. They often generate impossible future scenarios with the deceased relative to their difficulty imagining a realistic future.
The study reveals that peripheral glaciers in Greenland are losing mass at a rate of up to 50 Gigatons per year, contributing to around 15-20% of sea-level rise. This is higher than expected and more significant than the ice sheet alone.
Retention forestry and agroforestry systems offer a balance between production and biodiversity conservation. The paper proposes bridging the two fields to enhance ecological benefits and species conservation.
Researchers developed biodegradable nanoparticles that selectively target and resolve inflammation, potentially treating atherosclerosis and neurodegenerative diseases. The nanoparticles release an inflammation-resolving peptide drug, promoting tissue repair and reducing chronic inflammation.
A large observational study found no significant association between maternal vitamin D levels and children's bone mineral content, suggesting that UK guidelines for vitamin D supplementation during pregnancy may be overstated.
Assistant professor of astronomy Misty Bentz will receive a five-year $862,769 NSF grant to measure distances to galaxies with known black hole masses and obtain clearer images of galaxies to predict black hole masses. This project aims to develop a shortcut for predicting black hole mass in any given galaxy through simple observations.
Researchers at Intermountain Medical Center have developed a real-time electronic screening tool to identify patients with pneumonia, speeding up diagnosis and treatment. The tool analyzes over 40 variables to determine the probability of pneumonia, alerting caregivers when necessary.
A Swedish study found significant heterogeneity in continence rates among patients after radical prostatectomy, suggesting that some receive suboptimal care. The research used multivariate models to evaluate surgeon variation and identified a negative correlation between potency and continence rates.
Researchers at KAIST have developed a low-power phase-change memory using self-assembled nanostructures, which can store data even when not powered. The new technology reduces power consumption by up to 1/20th of its present level, making it suitable for mobile electronics applications.
A study published in the American Journal of Clinical Nutrition found that recalling recent meals reduces food consumption, while being distracted during eating leads to increased intake. Techniques such as writing down previous meals and using visual reminders can aid in reducing meal sizes.
The Boston University School of Medicine has launched a safe opioid prescribing education program, funded by the first of its kind $1.8 million grant from manufacturers of extended release/long-acting opioid analgesics. The program is designed to train healthcare providers on how to safely manage patients with chronic pain using opioids.
New research from the Niels Bohr Institute predicts a tenfold increase in extreme storm surges due to global warming, resulting in 'Katrina' magnitude storms every other year. The study suggests that 0.4 degrees Celcius warming already leads to a doubling of extreme storm surges and an additional 3-4 times increase with further warming.
Researchers at Oregon Health & Science University found that hospitals adopting Lean methodologies from Toyota and similar manufacturing approaches improved heart attack process of care measures, leading to lower 30-day mortality rates. However, no significant association with reduced readmission rates was observed.
A study has uncovered a rare congenital deformation in an early human skull from China, suggesting high levels of inbreeding among our ancestors. The finding provides valuable insights into human evolution and population dynamics, revealing unusual population dynamics likely caused by high levels of inbreeding.
A study found significant variation in vena cava filter use among California hospitals, with some hospitals using them up to 38.96% of the time. Hospital characteristics such as small bed count, rural location, and private status were associated with increased VCF use.
A study by Sanford-Burnham researchers found that Siah2 keeps androgen receptors constantly active in prostate cancer cells, enabling them to survive treatment. Inhibiting Siah2 may provide a new method for re-sensitizing castration-resistant prostate tumors to hormone therapy.
A solar storm was triggered by a fast coronal mass ejection (CME) approaching Earth, causing a mild geomagnetic storm with weak power grid fluctuations and minor impact on satellite operations. Aurora may be visible at high latitudes in northern US states such as Michigan and Maine.
A new University of Michigan poll shows that only one-third of parents follow their child's health care provider's advice all of the time. Most parents say they follow provider advice 'most of the time', but lower-income households and black and Hispanic parents are more likely to report following advice only occasionally.
Researchers have enhanced the ability of MEH-PPV polymer to confine light by reducing energy thresholds for laser production. The 'sandwich' approach limits exposure to oxygen and prevents degradation due to photo-oxidation.
A new study published in JAMA Internal Medicine found that biennial mammography screening for women aged 50-74 does not increase the risk of advanced breast cancer, but rather reduces the risk of false-positive results. For women under 50 with extremely dense breasts, annual screening may be necessary to decrease the risk of advanced d...
The EU-funded 'LUMINET' project aims to develop novel luminescent materials that minimize the use of rare earths. Researchers are exploring new methods to produce phosphors without these precious commodities.
Scientists at the University of Nottingham are leading a four-year study to investigate the effectiveness of tranexamic acid in treating intracerebral haemorrhage, a devastating type of stroke. The trial aims to recruit 2,000 people worldwide and assess whether the drug can reduce permanent brain damage and improve survival rates.
The remnants of ex-cyclone Tim are drifting west towards the Queensland coast, causing rough to very rough seas and moderate south to southeasterly swell. NASA's infrared satellite imagery shows the weakening storm with significantly warmed cloud top temperatures and strongest thunderstorms appearing in a small area offshore.
Researchers found that boiled Greek coffee consumption was associated with improved endothelial function and reduced blood pressure, even in those with high blood pressure. The study suggests that the polyphenols and antioxidants in this type of coffee may be beneficial for cardiovascular health.
Researchers found that individuals with autism have broader tuning of neurons in the fusiform face area, leading to difficulties in recognizing faces. This impairment affects social interactions and limits facial expression understanding.
Researchers found that adding pimples to equipment doesn't necessarily improve grip, but rather the density of pimples and texture of mitts matter. Synthetic leather mitts performed best across all conditions, suggesting a need for tailored ball designs for different climates.
A study describes 9 new wasp species of the Paramblynotus genus from Africa and Madagascar, adding to the already rare Mayrellinid family. The discovery provides insights into the biology and ecology of these parasitoid wasps.
Researchers found that tourist-fed stingrays at Stingray City show distinct patterns of activity, including daytime feeding and nighttime resting, compared to wild stingrays. Human interaction has drastically altered their behavior, with some stingrays abandoning their solitary nature and forming schools.
The California chromodorid sea slug, declared extinct in Southern California in the 1980s, has begun to reappear in local waters. Marine scientists attribute its resurgence to improved water quality, mainly a result of stricter pollution regulations.
A study reports a rising rate of propofol abuse among health care professionals, characterized by rapid onset and quick recovery time, with most abusers being women with depression and history of childhood trauma. The study suggests that propofol abuse can lead to unintended side effects, including physical injuries and loss of control.
Researchers found that pneumonia patients are nearly twice as likely to develop depression and cognitive impairments, which can lead to disability and nursing home admissions. Hospitalization for pneumonia also increases the risk of losing daily life activities.
Researchers reconstructed ancient ocean conditions, finding most deep ocean was anoxic, with limited oxygen and hydrogen sulfide. This discovery challenges our understanding of eukaryote rise and animal emergence.
A study found that elevated PAPP-A levels were associated with a higher risk of cardiovascular events in people with cardiac chest pain due to heart disease. The presence of PAPP-A also predicted cardiovascular events, including heart attacks and strokes, even after controlling for other factors.
Large chunks of the Farallon oceanic plate are still present under parts of central California and Mexico, according to new research. The researchers used seismic tomography and other data to show that part of the Baja region and part of central California sit atop 'fossil' slabs of the Farallon plate.
Researchers propose a novel risk stratification model for bladder cancer patients treated with radical cystectomy, utilizing clinico-pathological and pre-operative hematological factors. The study found that low hemoglobin and high C-reacted protein levels are independent prognostic indicators for disease-specific survival.
A UM doctoral student uses Twitter to share updates from a conservation conference, reaching over 100,000 users worldwide. The study highlights the potential of live-tweeting to promote conservation education and outreach.
Researchers have discovered that mutations in the TERT promoter gene are involved in some brain tumors and certain types of cancer. The study found nine tumor types highly associated with these mutations, which may provide a new target for drug development.
Researchers from New York University and Carleton University find that Earth's interior cycles cause sea-level rise and global warming through mantle plumes. The analysis reveals a connection between geological events below the surface and climate change, suggesting a powerful union between deep-sea geological events and climate shifts.
A new study warns that widespread adoption of the 'test and treat' policy for HIV could lead to a significant increase in multi-drug resistant HIV cases. The study suggests that this approach could double the number of MDR cases among men who have sex with men (MSM) in LA County over the next 10 years.
Researchers have discovered the original host of ancient pigmy moths was a rainforest plant in the myrtle family. The moths' evolution reveals unique adaptations for courtship and mating.
Weizmann Institute researchers found that measuring a single atom's spin can collapse its superposition into one state. By adjusting the polarization of the emitted photon, they demonstrate that observers can influence the spin collapse, suggesting an 'action-at-a-distance' effect.
Researchers used computer simulations of water to predict its behavior under extreme pressure and temperature. The results suggest that magnesium carbonate, previously thought insoluble, can dissolve in water at great depths, potentially returning carbon to the surface through volcanoes.
Researchers at the University of Oregon have synthesized organic molecular structures that can move both positive and negative electrical charges. This breakthrough has significant implications for creating flexible electronic devices, such as stretchable and bendable computers and synthetic skin for robots and prosthetics.
Researchers at the Weizmann Institute of Science created a two-dimensional cell-like system on a glass chip, enabling precise observation of gene expression and protein behavior. The system allows for the simultaneous production and trapping of multiple proteins, revealing a spectrum of protein activities.
A one-day training program designed by U of A medical researchers led to officers being more likely to recognize mental health issues during calls and less likely to use physical force. The training resulted in long-term behaviour change and saved the police force $80,000 due to increased efficiency.
Around half of Cambodia's tropical flooded grasslands have been lost in 10 years, threatening biodiversity and livelihoods. The area has shrunk from 3349 km² to 1817 km², with intensive commercial rice farming being a major driver of the destruction.
Researchers have found that macrophages help produce and eliminate red blood cells, which could lead to novel therapies for diseases affecting red blood cell balance. The study also showed that eliminating certain macrophages can normalize abnormal red blood cell counts in conditions like polycythemia vera.
Researchers analyzed over 70 years of hourly precipitation data from 13 US sites to test the hypothesis that storms are becoming more frequent and intense as the climate warms. They found a significant steady increase in stormy activity on the Olympic Peninsula in Washington State, which is famously prone to drizzle.
A new study by UC Irvine scientists has found that ocean plankton near the surface of warm waters are much more carbon-rich than previously assumed. The researchers' findings challenge the Redfield ratio, a core principle in marine science that was thought to be constant across different depths and locations.
A recent study reveals that the deepest oceanic trench holds a surprisingly high concentration of bacteria in its sediment, up to 10 times more than surrounding abyssal plains. This discovery highlights the critical role microorganisms play in regulating the global carbon cycle and climate regulation.
A large multicentre study found that small kidney tumours can have an aggressive potential and should be treated. The study included 2197 patients with RCC of 4 cm or smaller and showed that the risk of nodal disease or distant metastasis increased significantly with rising tumour diameter.
A UK study found that epigenetic changes play a key role in the development of chemotherapy resistance in bladder cancer. The researchers identified DNA hypermethylation as a potential biomarker to predict response to treatment, which could increase pathological complete response rates and spare nonresponders from adverse events.
Researchers found that mycolactone, a lipid toxin from Mycobacterium ulcerans, causes cytoskeletal dysregulation by activating the protein N-WASP. This led to defects in cell adhesion and migration, impairing skin integrity. The study suggests using N-WASP inhibitors as potential treatments for Buruli ulcers.
Researchers developed a novel multimodal imaging approach to detect frontotemporal degeneration, showing improved diagnostic specificity and accuracy. The method integrates measures of white matter and grey matter, enabling the screening of patients for clinical trials.
Researchers found that nano-hMSCs can promote cavernous neuronal regeneration and repair erectile dysfunction. The study revealed that transplantation of nano-hMSCs increased the expression levels of cavernous neuronal, endothelial, and smooth muscle makers.
A large observational study conducted by a group of researchers in Sweden and the Netherlands suggests that surgery offers better survival benefits than radiotherapy for men with localized prostate cancer, especially in younger age groups and those with fewer comorbidities. The study found that radical treatment, preferably surgery, is...
Researchers discover that unhealthy eating behaviors can worsen moods in women without prior mood changes, leading to a better understanding of the relationship between emotions and eating. The study's findings suggest that this connection may play a role in the development and maintenance of unhealthy eating habits.
A joint Swedish-UK study found that men who participated in biennial PSA-based screening had lower risks of being diagnosed with and dying from prostate cancer for up to 9 years. After 9 years, the rates in both groups converged, but mortality was significantly lower in the screening group initially.