Researchers at Wake Forest Baptist Medical Center studied 120 men undergoing hormone therapy for prostate cancer and found that neither soy protein nor an antidepressant provided relief from hot flashes. The study highlighted the need for treatments specifically developed for men with hot flashes.
The study, involving 180,000 students across 34 countries, found that strong parental support and early literacy activities are crucial for academic success in reading, math, and science. Researchers discovered that students from homes with educated parents and access to reading materials tend to perform better in school.
Researchers at Loyola University Chicago Stritch School of Medicine have discovered that combined radiation and burn injuries trigger 100 times greater bacterial leakage across the intestinal lining, leading to sepsis and death. This finding could lead to new treatments for survivors of nuclear disasters.
Lihong Wang has received a $3.5 million NIH grant to translate his single-cell label-free photoacoustic microscopy technology into the clinic for cancer screening, detection, prognosis, and monitoring.
According to a new hypothesis, black holes may have distinct features, dubbed 'hair', which are influenced by the surrounding matter. This concept contradicts the traditional 'bald' model proposed by Roy Kerr in 1963.
Cassini's Composite Infrared Spectrometer (CIRS) detects propylene, a chemical used in food-storage containers and car bumpers, on Titan's lower atmosphere. The detection fills a mysterious gap in Titan observations dating back to NASA's Voyager 1 spacecraft.
Researchers at the University of New South Wales discovered the genetic secrets of Antarctic extremophiles that can thrive in extremely cold and salty water. The study found that these microorganisms engage in extensive DNA swapping, enabling them to coexist despite their vastly different niches.
The National Institutes of Health has awarded a $5.9 million grant to the Geisel School of Medicine at Dartmouth for its Lung Biology Center of Biomedical Research Excellence. This funding supports cystic fibrosis research and translates basic science into clinical applications.
Researchers at Virginia Tech aim to improve understanding of how environmental conditions affect the influenza virus's ability to survive and infect others while airborne. The project seeks to clarify why humidity affects the virus's transmission.
Researchers have developed a new blood test that can detect cancer metastasis in dogs by analyzing cell-free DNA in blood plasma. The test has shown promising results in detecting minimal residual disease and tracking tumor progression, with potential implications for human cancer treatment.
A national study of 2 to 5 year olds shows that psychotropic prescription use has leveled off since 2006. The likelihood of receiving behavioral diagnoses increased during this time but was not accompanied by a corresponding increase in psychotropic prescriptions.
Researchers discovered that aspirin improves survival in patients with colon cancer whose tumour cells express Human Leukocyte Antigen class I (HLA class I), a cell-surface protein involved in the immune system. The study found that HLA class I could be used to predict which patients benefit from aspirin therapy.
A CU Cancer Center study found that young patients with metastatic colorectal cancer have a higher risk of treatment failure and worse survival rates compared to middle-aged patients. The study analyzed data from over 20,000 patients and showed a significant increase in disease progression and death among those under 40.
A clinical trial suggests that combining radiotherapy with an anti-cancer drug called APG101 blocks a cell-signalling pathway crucial for glioblastoma development. The treatment showed promising results, with patients receiving the combination therapy living longer than those treated with radiotherapy alone.
Aaron Esser-Kahn, Sunil Gandhi, and Ali Mortazavi will each receive $2.3 million to fund their projects, focusing on vaccine development and neural plasticity. Their work aims to improve human health by transforming scientific fields.
A study by Brown University researchers found that Medicare Advantage health plans significantly understated their rate of high-risk medication prescriptions. The average plan reported a 5.8 percentage point difference in favor, resulting in about 500,000 more seniors receiving high-risk medications than reported.
A new study aims to investigate the potential of exercise in treating and preventing heart failure with preserved left ventricular ejection fraction (HFPEF). The OptimEx study will examine the effects of different exercise protocols on HFPEF, including their impact on pathophysiological mechanisms and clinical outcomes.
Researchers developed nanowires that block lithium diffusion, promoting layer-by-layer lithiation and potentially minimizing cracking and improving durability. This breakthrough could lead to more effective electrode architectures for lithium-ion batteries.
Researchers at the University of Michigan have developed a microfluidic chip that can capture elusive circulating tumor cells from blood, supporting their growth for further analysis. This technology has the potential to revolutionize cancer diagnosis and treatment by providing accurate prognoses and testing treatment options on cultur...
Researchers have gained a better understanding of how cells deal with DNA damage that can contribute to cancer and other diseases. The study identified new prospects for developing cancer therapies by targeting the protein nucleolin to enhance sensitivity of tumor cells to radiation or chemotherapies.
Researchers at IRB Barcelona have identified a crucial protein called dBigH1 that regulates zygotic genome activation in the fly Drosophila. This discovery has significant implications for understanding embryonic development and potential connections to infertility, gestational disorders, or early miscarriage.
Research from Aarhus University shows that exposure to a farming environment can prevent or dampen hypersensitivities and allergies, even in adults. The study found that working in farming environments stimulates the immune system, dampening its response to environmental irritants, which may trigger hypersensitivity.
People are increasingly using virtual tombs, tattoos, and mourning apparel to honor the dead. According to Baylor researcher Candi Cann, these 'do-it-yourself' memorials offer personal alternatives to traditional rituals.
Researchers at UCLA have created a synthetic metabolic pathway that converts all six glucose carbon atoms into three molecules of acetyl-CoA without losing any as carbon dioxide. This breakthrough could lead to a significant increase in the production of biofuels, with potential applications in biorefineries and photosynthetic microbes.
A new tool has been developed to resolve the structure of membrane-embedded and membrane-associating proteins by exploiting the unique water dynamics gradient across and above the lipid bilayer. This breakthrough can help determine the location and structure of protein segments at the surface of membranes.
A team of neuroscientists has identified a specific area in the visual cortex called V4 that is involved in creating illusory contours. The brain's neural activity in this region correlates with the perception of these illusions, which are thought to be an evolutionary adaptation for detecting predators or prey.
Researchers discovered a mechanism by which damaged mitochondria signal their own destruction, allowing cells to thrive. The 'eat me' signal involves cardiolipins and a protein called LC3, opening doors to potential research into cures for Parkinson's disease.
A study published in JAMA Internal Medicine compared the cardiovascular safety of conjugated equine estrogens (CEEs) and oral estradiol. The research found a greater risk of venous thrombosis associated with CEEs, but no increased risk of heart attack or ischemic stroke.
Tropical Depression 22W is taking a different route than Tropical Depression 21W and heading northwest towards Koror, Palau. Favorable environmental conditions will allow the depression to strengthen into a typhoon over the next two days.
Researchers found that C6' treatment reversed abnormal nitric oxide signaling in mice with and without sickle cell disease, resulting in normalized erectile functioning. The compound's potential extends beyond treating priapism to vascular and circulatory disorders.
A study published in Pediatrics shows a significant increase in emergency room visits for children with sports-related traumatic brain injuries, including concussions. The number of admissions also rose, with patients with less severe injuries being treated in the hospital more frequently.
A team of scientists has developed a process to connect an autism-linked gene to its function. They found that mutations in the NHE9 gene cause communication problems among brain cells, contributing to autism. The study used a step-wise strategy to screen variants and identified changes that affect endosomal pH, altering cell traffic.
New research from the Children of the 90s study at the University of Bristol suggests that fish accounts for only seven per cent of mercury levels in the human body. This finding has significant implications for official advice warning against eating too much fish during pregnancy, which may need to be reviewed.
A recent study published in the Proceedings of the National Academy of Sciences has discovered that two sets of nerve receptors in the skin convey information about fine textures through vibrations. This finding suggests that humans can discriminate between different fine textures, such as silk and satin, through these subtle vibrations.
A new study suggests that regular leisure-time exercise can significantly lower the risk of developing high blood pressure. Researchers found that individuals who exercised for four hours or more per week had a 19% lower risk compared to those who exercised less than one hour per week.
People with poorly controlled diabetes are at risk of experiencing hypothermia, frostbite, and dehydration when traveling to high altitudes. Insulin needs may also increase or decrease due to environmental extremes, exercise, and dietary changes.
Researchers discovered haloarchaea dominate Deep Lake's microbial community, exchanging DNA among species and genera. The microbes' ability to share genetic information enables specialization, coexistence, and adaptability.
The TRMM satellite observed a 'hot tower' near the center of Tropical Depression 11, indicating it would strengthen into Tropical Storm Jerry. The storm later strengthened with maximum sustained winds near 40 mph.
The study reveals that membrane proteins use a dynamic, constantly changing state to transport proteins across the outer membrane without requiring energy. This finding provides an exceptional insight into the transport mechanism and has implications for understanding protein folding and transport in bacteria.
Researchers analyzed data from 33,488 live births to find that early-term births (37-38 weeks gestation) are associated with higher risks of birth complications, including hypoglycemia, respiratory support, and NICU admissions. Cesarean deliveries among early-term births also pose a significant risk for NICU admissions and morbidity.
Research found that patients with more primary care visits have lower colorectal cancer incidence and mortality rates. Increasing access to primary care may reduce the national burden of CRC.
Researchers at Rice University used synthetic biology to study how biochar affects microbial communication. Biochar was found to interfere with certain conversations between microbes, potentially impacting plant growth.
A Commonwealth Fund survey finds that over three-quarters of US adults are aware of the ACA's individual mandate, while only four in ten know about new health insurance marketplaces and premium subsidies. Broad support for expanding Medicaid is also evident, with 68% of adults favoring it in their state.
Researchers at DESY's PETRA III light source have created a 4.3nm-wide X-ray beam, ten thousand times thinner than a human hair, using a Fresnel lens made from nanometre-thin layers.
Typhoon Wutip made landfall near Dong Hoi, Vietnam, with a 10-mile-wide eye, prompting evacuations of over 140,000 people. The storm's heavy rains are expected to cause flooding and landslides in Vietnam's central highlands.
NASA's Aqua satellite captured infrared data on Tropical Depression Sepat, revealing some strong thunderstorms and cold cloud tops near the center of circulation. The storm is expected to track over a pool of cooler waters, hindering its development, and may briefly strengthen into a tropical storm before weakening again.
Scientists at University of Wisconsin-Madison discover that zinc ions play a crucial role in maintaining protein stability. A shortage of zinc can cause proteins to misfold and clump together, leading to cell death. Researchers identify a 'protein chaperone' called Tsa1 that prevents protein aggregation and maintains cellular balance.
The NIH has awarded $17 million to support genomics research in Africa, enhancing the continent's research capacity and training African genomic scientists. The new grants will study various health conditions important in Africa, including neurological disorders and respiratory diseases.
Scientists at Scripps Research Institute have created a comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete insulin. The finding makes possible a deeper scientific understanding of the insulin secretion process and how it fails in insulin disorders such as type 2 diabetes.
A study found that bed sharing increased among black and Hispanic families, with black infants sharing beds most often. The percentage of black infants usually sharing a bed increased from 21.2% in 1993 to 38.7% in 2010.
Experts advocate for widespread screening of 'Baby Boomer' generation in Canada due to high prevalence and lack of awareness. Early treatment makes hepatitis C curable, saving lives and reducing healthcare costs.
The Change AGEnts Initiative aims to create change in healthcare practice that improves the health of older adults. The project, funded by a $5 million grant from the John A. Hartford Foundation, brings together researchers, clinicians, and health system leaders to develop and implement evidence-based models.
Researchers found JAM-A facilitates immune cell recruitment to arteries, promoting plaque formation. Reducing JAM-A levels can slow lesion growth, but deleting the molecule from monocytes causes damage and increases plaques.
Charles P. O'Brien, a leading expert on alcohol dependency, is being honored with the French Legion of Honor Medal for his pioneering work in addiction treatment. He has made significant contributions to the field through his research, advocacy, and leadership.
Researchers at Huntsman Cancer Institute will study the role of the c-KIT gene in melanoma, a devastating skin cancer that often develops resistance to treatment. The new funding will support studies using a novel melanoma mouse model to test whether active c-KIT can initiate melanoma.
Researchers found evidence of massive ice sheets over 1km thick in the Arctic Ocean, contradicting previous assumptions that glaciations only occurred on continents. The discovery reveals four or more generations of ice masses in the region, covering an area as large as Scandinavia.
Researchers have successfully grown large numbers of patient-specific brain cells in the lab using small biopsies, which express natural protective agents. These cells may be used to treat a range of neurological conditions and could potentially cross the blood-brain barrier to deliver targeted therapies.
Researchers at the University of Washington have created a programming language for chemistry that allows scientists to design and build custom DNA molecules with specific functions. This new approach enables flexible control over chemical reactions, which could lead to innovative medical applications such as smart drug delivery systems.
A study analyzing UK music charts over four decades found a significant increase in alcohol references, with almost one in five top 10 songs featuring alcohol-related lyrics. Researchers warn that these messages may be reaching larger audiences than traditional advertising, posing a concern for young people's drinking behaviors.
A new study by Yale University researchers found that older adults are more risk-averse than their midlife counterparts when choosing between possible gains, but more risk-seeking when choosing between losses. The study suggests important policy implications for decision-making across the lifespan.