Researchers have designed a guideline for physicians and patients with Androgen Insensitivity Syndrome (AIS), a rare condition that prevents tissues from responding to male hormones. The guideline includes follow-up protocols from birth to adulthood, therapy options such as hormone replacement therapy, and more.
Researchers at the University of Minnesota have identified an enzyme called APOBEC3B as a key player in causing DNA mutations found in most breast cancers. The discovery may lead to new diagnostic methods and treatments that can prevent or block these harmful mutations, offering hope for improved breast cancer outcomes.
Researchers found a Florida-sized zone of partly molten rock beneath the Pacific Ocean, which could trigger massive eruptions. The collision between two or more continent-sized piles may lead to supervolcano-like eruptions and large igneous provinces.
Researchers have discovered that TRF2 suppresses DNA damage response by blocking signaling pathways, preventing chromosomes from sticking together. This finding has implications for understanding cancer and the aging process, as telomere shortening can lead to chromosomal instability.
Researchers identified a protein trafficking defect in brain cells that may underlie common non-familial forms of Parkinson's disease. The defect is related to genetic variants in two genes, LRRK2 and RAB7L1, which disrupt protein sorting and lead to the accumulation of protein aggregates.
Research finds older bikers three times as likely to be seriously injured in crashes compared to younger adults. Middle-aged bikers also face increased injury risks, particularly fractures and internal organ damage.
A Stanford researcher has developed a non-invasive technique to measure the mechanical properties of an intact spider web, revealing surprising variations in stiffness and supercontraction. The study provides insights into the behavior of nature's strongest material and its potential applications in engineering bio-inspired materials.
A recent international conference focused on point-of-care healthcare technologies, with NJIT Distinguished Professor Atam Dhawan predicting a paradigm-shift in global healthcare. The conference highlighted the need for affordable and accessible healthcare solutions, particularly in developing nations.
A new study by Karl Zimmerer and colleagues found that small-scale farmers in Bolivia, Peru, and Mexico can successfully cultivate genetically diverse local crops alongside intensive agriculture. These farms often rely on remittances from migrant communities, which enables them to maintain agrobiodiversity maize.
Researchers found that Tai Chi significantly reduced falls among adult stroke survivors, improving both static and dynamic balance. The study involved 89 participants who practiced either Tai Chi or usual care for 12 weeks, with the Tai Chi group experiencing fewer falls.
A study found that people who grew up in states with lower minimum drinking ages were more likely to binge drink later in life. The researchers tracked over 39,000 participants and found that those who lived in states with lower drinking ages were 19% more likely to binge drink monthly, especially among men who didn't attend college.
Researchers have identified 10 new species of semi-aquatic freshwater earthworms in Thailand, showcasing the country's astonishing biodiversity. These unique creatures play a crucial role in decomposing organic matter and improving soil properties, making them valuable assets for organic rice farming.
A new study recommends using air curtains and cooling layers to preserve China's Terracotta Warriors and other historic relics. The measures aim to prevent environmental degradation and protect the over 1,500 relics in large museums like the Qin Terracotta Museum, which attracts over 5 million visitors annually.
Fish can determine their size relative to others using chemical cues alone. This ability helps form groups with strength in numbers, reducing individual risk from predators. The study found that both species used chemical self-referencing to locate similarly sized fish of the same species.
Researchers found that Bacteroidetes were more predominant in fine dust, while Proteobacteria were associated with coarse sediments. This knowledge can inform management practices to minimize damage to soils caused by wind erosion.
A new study by Hospital for Special Surgery found that approximately 25% of ACL tears from recreational ski injuries can heal on their own. Researchers developed a six-to-12-week test to identify patients with low-grade ACL injuries who are likely to recover without surgery.
Researchers identified a compound called TIC10 that stimulates the tumor suppression capabilities of TRAIL, inducing cancer cell death in mice. The compound is effective in cancer cell samples and cell lines resistant to conventional therapies, showing promise as a new treatment option for advanced cancer.
A study found no clear evidence linking increased gluten in new wheat varieties to the rise in celiac disease. Instead, overall gluten consumption has risen due to increased vital gluten and wheat flour consumption.
A new study has found that widely used nanoparticles accumulate in soybean plants grown in farm soil, which could have health implications. Zinc oxide and cerium dioxide, commonly used in cosmetics, were detected in the reproductive/edible portions of the soybeans.
Researchers have developed a high-efficiency process that converts various biomass types into crude bio-oil, yielding an energy efficiency of 85-90%. The process is environmentally friendly and accepts all kinds of biomasses, with potential to replace fossil fuels in transportation.
Researchers identified two new genes associated with severe early-onset heart rhythm disorders, expanding the list of culprits that can cause sudden cardiac death. Exome sequencing revealed de novo mutations in calmodulin genes, which impaired calcium binding and led to abnormal electrical activity in the heart.
A UCLA team developed a degradable nanoscale shell to carry proteins to cancer cells, stunting tumor growth and inducing cell death. The process is safer than traditional chemotherapy and gene therapies, preserving healthy cells.
Researchers identified a mutant mouse model of schizophrenia that exhibits mild chronic brain inflammation and cognitive deficits. The study found that Shn-2 deficiency leads to an 'immature Dentate Gyrus', which produces schizophrenia-related phenotypes. Chronic administration of anti-inflammatory drugs rescued working memory deficit ...
A $1.7 million grant will fund research on biofilm formation in dental stomatitis, a fungal infection affecting 50-75% of denture wearers. The study aims to determine the role of biofilms in disease development and develop novel immunotherapies targeting biofilm growth.
A four-month instructional dance program for Latino seniors aims to increase their level of physical activity, balance, and cognitive function. The BAILAMOS program, led by UIC associate professor David Marquez, seeks to prevent disability among this disadvantaged group.
Researchers at MIT found evidence of two separate collisional events: one 50 million years ago and another 10 million years later. The team analyzed rocks from the Himalayas and discovered a new timeline for India's collision with Asia, suggesting that part of ancient India 'Greater India' was smaller than previously thought.
A recent study published in Kidney International found that higher levels of omega-3 fatty acids in the blood of patients starting hemodialysis were associated with a lower risk of sudden cardiac death. The five-year survival rate for dialysis patients is 35%, with sudden cardiac death being a major cause of mortality.
A new study finds that consumers respond positively to free products and services, leading to increased demand and higher revenue for businesses. The research, published in the Journal of Marketing Research, shows that switching from a two-part plan to a three-part plan can increase revenue by up to 19.7%.
The Northwell Health system has received a federal grant to train Hampton University students on the racial disparities in prostate cancer treatments. The program aims to improve treatment outcomes for African American men, who are disproportionately affected by the disease.
The journal features world-class content on innovative applications of emerging space-based technologies, including commercial cargo and crew services, tourism, colonization, deep space research, and resource utilization. The first issue includes an original article on the B612 Foundation Sentinel Space Telescope and a roundtable discu...
Researchers propose using two EGFR-blocking antibodies to treat triple-negative breast cancer, which lacks common receptors for hormone-based treatments. In a study, combining two antibodies proved effective in preventing tumor growth and spread in mice.
Researchers investigate coral specialization in the ocean, finding that habitat depth is a key factor in shaping different species. Coral larvae can disperse vast distances but small differences in survival rates at different depths lead to segregation over long generation times.
The number of ACL injuries in young athletes is rising due to increased training and reduced free play. Pediatric orthopaedic surgeons recommend optimal strategies for treating ACL injuries based on the specifics of the injury and the child's skeletal maturity, including non-surgical management and surgical reconstruction.
New research reveals that exposure to air pollution and cockroach allergen early in life can increase the risk of developing an asthma-related cockroach allergy by age 7. Children with a common mutation in the GSTM gene are especially vulnerable to this increased risk.
Researchers used a unique X-ray instrument to analyze decades-old paint samples and determine that Picasso used common house paint, known as Ripolin. This discovery offers insights into the development of new materials and sustainable energies.
Research suggests that being overweight is a risk factor for gum disease, which can lead to chronic inflammation and other health issues. Daily brushing, flossing, and professional cleanings are essential for preventing gum disease and maintaining good oral health.
A 10-year study found that diverse ecosystems are less likely to collapse after disturbances like climate change or pest invasion. Researchers suggest encouraging more types of plants in fields and woods to mitigate ecosystem damage.
Researchers at TUM and PSI have developed a method to visualize material fluctuations and nanostructures using X-ray microscopy. This technique relaxes the hard restrictions of immobility required for high-quality imaging, enabling the visualization of previously inaccessible objects.
Scientists at Virginia Commonwealth University Massey Cancer Center discovered a novel combination of drugs that selectively destroys lymphoma cells through apoptosis. The experimental therapy combines ibrutinib and bortezomib, with the latter being relatively non-toxic to healthy cells.
The study found that increased breast milk intake by 10 milliliters per kilogram per day reduced the odds of sepsis by almost 20%. Breast milk also lowered NICU costs by $20,000 to $32,000 per day. This research is significant for its economic impact on risk of infection and related hospital care costs.
Research finds that self-esteem, optimism, and perceived control influence depression in both stroke survivors and their spouse caregivers. High levels of these factors in one partner can lead to lower levels of depression in the other. Interventions targeting both partners may improve patient outcomes.
Researchers from San Francisco State University found that nitrogen boosts the growth and toxicity of phytoplankton that produce a potent toxin called domoic acid. These diatoms can cause Amnesic Shellfish Poisoning in humans and death among marine mammals and seabirds.
The European Space Sciences Committee (ESSC) has released its position statement on the ESA council meeting at ministerial level, commenting on the impact of decisions taken. The ESSC recommends prioritizing scientific return in the Science Programme and reiterates its support for European involvement in the Global Exploration Strategy.
A team of researchers at the University of California, Riverside, has discovered a genetic mechanism that explains how Phytophthora pathogens compromised the potato plant's immune system during the Irish Famine. The study reveals that RNA silencing pathways are suppressed by effectors, leading to an increase in susceptibility to disease.
Researchers mapped brain regions where individual differences occur, finding variability in areas integrating information and controlling attention. This study provides insights into brain evolution and development, potentially linking diversity of human abilities to specific brain region expansions.
A study by University of Exeter researchers reveals tropical forests' sensitivity to climate change, with significant carbon release expected if climate models are inaccurate. The team found a correlation between year-to-year variations in carbon dioxide concentration and long-term changes in tropical forest carbon storage.
Scientists have developed a cheap and quick method to detect mercury contamination in water using a mobile phone. The technique involves placing a special sheet in the water, which changes color in the presence of mercury. Photographing the sheet with a mobile phone can even quantify the concentration of mercury.
Researchers found that cues for rewards can instantly transform motivation, with even unpleasant events becoming desired. The study used salt appetite to demonstrate how powerful neural mechanisms can turn a repulsive cue into an attractive one.
A Mayo Clinic-led study has identified two biomarkers, IGFBP-7 and TIMP-2, that can detect acute kidney injury in urine, allowing for early intervention and improved patient outcomes. The study's findings have the potential to revolutionize the diagnosis and management of this deadly condition.
Researchers found evidence of a 'penultimate outburst' in a massive star before its final detonation as a supernova, providing the first causal link between the two events. This discovery has significant implications for our understanding of what triggers a supernova.
A large international study of over three million births found that higher particulate air pollution levels were associated with increased rates of low birth weight. The study, published in Environmental Health Perspectives, highlights the need for policy makers to address air pollution to prevent serious health consequences.
A study found that more than a third of adults with COPD were prescribed benzodiazepines, despite warnings about their potential harm. The most vulnerable group, those with severe COPD, used the medication at the highest frequency and with the most repeat prescriptions.
A new study finds that happiness increases with age, but a person's overall level of well-being depends on when they were born. Life satisfaction increased over time for each birth cohort, while those born earlier in the 20th century had lower levels of well-being due to economic conditions.
A study found that traumatic brain injury complications, including cerebral vasospasm and intracranial hypertension, are prevalent among US combat soldiers. Researchers analyzed data from 122 patients with traumatic brain injuries and found that over 40% had high intracranial pressure.
Research found Native Hawaiians and Pacific Islanders have a higher risk of intracerebral hemorrhage before age 45 compared to non-Hispanic whites. The study revealed that Native Hawaiians were 54 years old when they had a hemorrhagic stroke, whereas non-Hispanic whites were 68 years old, highlighting the disparity in vascular health.
A recent issue of ZooKeys published 27 new moth species from North and South America, including the Neotropical tigermoth family. These discoveries expand the geographic reach of moth diversity in the region.
A new study found that women who accurately perceive their heartbeats are less likely to view their bodies as objects, reducing the risk of eating disorders and other mental health issues. The study provides valuable insights into the importance of internal body awareness for maintaining positive body image.
A University of Miami study reveals that people tend to seek higher-calorie foods when they perceive tough times, consuming nearly 40% more than neutral messages. In contrast, low-calorie food prompts a 25% reduction in consumption.
Researchers from the Marine Biological Laboratory discovered that lancelets have melanopsin-producing cells, which are involved in non-visual light-dependent functions. Studying these cells provides insight into the evolutionary history of circadian receptors and their role in regulating biological clocks.
Researchers found that African American and Latino men who have sex with men voluntarily used health-related Facebook groups to discuss HIV knowledge, stigma, and prevention, leading to increased requests for home-based HIV tests. The study suggests social media can be a useful tool for collecting and analyzing data, saving money and i...