A recent NIH-funded study found that using advanced imaging shortly after an acute ischemic stroke did not identify a subgroup of patients who could benefit from clot removal procedures. The study, MR RESCUE, tested an invasive clot removal strategy in patients with large clots blocking major brain arteries.
Researchers at Pitt/UPMC successfully used brain-computer interface (BCI) technology to enable a paralyzed man to control a computer cursor and robot arm with his thoughts. The study, published in PLoS ONE, demonstrates the potential for BCI technology to help individuals regain independence after spinal cord injuries.
A team at Vienna University of Veterinary Medicine found the same strain of Usutu virus in dead blackbirds in Italy in 1996 as in Austria's cases. This suggests the virus was present in Italy before reaching Europe, and forensic pathology can help unravel origins of emerging diseases.
Research shows that babies of immigrant mothers in Ontario have higher birth weights compared to babies born in their mothers' native countries. The weight differences are more pronounced for babies born in poorer, less developed countries.
University of Notre Dame Sociologist Elizabeth McClintock's research offers new insights into physical attractiveness and age on mate selection. Her studies show that very physically attractive women are more likely to form exclusive relationships, while thinner women report fewer sexual partners.
The NASA's Mars Atmosphere and Volatile EvolutioN (MAVEN) spacecraft is undergoing rigorous environmental testing at Lockheed Martin facilities. The tests simulate extreme temperatures, vacuum, and vibration to ensure the spacecraft can operate in space.
Research suggests that monitoring hepatic function with HIDA SPECT prior to and during radiation therapy can help tailor treatment plans for unresectable liver cancer patients. This assessment method allows for personalized radiation doses while minimizing the risk of liver injury.
A study exploring the impact of early parental death found that individuals experiencing bereavement as children are more likely to experience low self-esteem, loneliness, and isolation in adult life. Researchers recommend providing essential practical support and maintaining social networks to mitigate these effects.
Scientists studied evolutionary rates of nearly 20,000 human genes and found that genes involved in the same biological pathways change their rate of evolution in parallel. This signature can help identify partner genes that may work together in biochemical pathways, providing clues to their function.
A new study has found that bronchiectasis is independently associated with an increased mortality risk in patients with moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD). The presence and severity of bronchiectasis were linked to a higher risk of death, independent of other known risk factors.
A subset of regulatory T cells has been identified that can remove pathogenic T cells, inhibiting disease progression in RA-like conditions. Small proteins have also been found to induce more of these beneficial T cells.
Researchers developed a diffusion abnormality index (DAI) to measure brain tumor response to radiation therapy. The study showed that changes in DAI can predict post-treatment response with high sensitivity and specificity.
Researchers analyzed blood plasma samples from mice to identify protein traits associated with genetic markers, paving the way for diagnostic and therapeutic targets
Researchers at Dana-Farber Cancer Institute have developed a new approach to treating autoimmune diseases like rheumatoid arthritis. Infusing CD8+ Treg cells into arthritis-prone mice shut down the inflammatory cascade that damages tissues and joints, significantly slowing disease progression.
Scientists review research on dog cranium development to identify genetic variations that may inform human skull development. The study suggests a connection between canine and human craniofacial development, potentially leading to new insights into craniofacial deformities such as Apert, Crouzon, and Pfeiffer syndromes.
Artificial bone created using stem cells and lightweight plastic can heal shattered limbs by encouraging real bone growth. The implant's honeycomb structure allows blood to flow through it, supporting the attachment of patient-derived stem cells.
A phase II clinical trial shows that selumetinib, a targeted therapy, can halt growth or shrink tumors in 15% of patients with recurrent low-grade ovarian cancer. The two-year overall survival rate is 55%, and the median overall survival has not been reached due to high patient survival rates.
A study by Georgetown University researchers found that requiring premiums for public health insurance coverage can counteract its expansion effects. The Affordable Care Act subsidies play a crucial role in making health insurance more affordable, affecting the number of uninsured individuals.
Researchers used Twitter data to model how lifestyle factors such as social status, pollution exposure, and interpersonal interaction influence health. They found that even people who regularly talk about exercising get sick more often than those who actually exercise.
A new study by researchers at the University of Bergen found that an iPhone app, iDichotic, produces as reliable results as laboratory tests. The app measures brain function in language processing and attention, opening up new possibilities for psychological research and remote testing.
The German Academic Exchange Service is funding a joint project on spintronics, aiming to develop energy-efficient IT devices. Researchers from Johannes Gutenberg University Mainz and international partners will focus on the field of spintronics.
Researchers have identified a new mechanism by which the bladder senses its level of fullness through integrin proteins. This discovery may lead to the development of new drugs targeting this pathway to treat overactive bladder and incontinence.
Researchers at UC Davis have uncovered a biological mechanism by which harmful bacteria thrive in the guts of those with inflammatory bowel disease (IBD). The discovery may lead to new treatments with fewer side effects than current therapies, targeting molecular pathways that generate nitric oxide and nitrate.
Ant pupae employ acoustics to signal their rightful place in the colony's hierarchy, influencing adult ants' behavior. Researchers discovered that pupae make sounds similar to adults with 'file and scraper' organs, essential for maintaining social status.
Researchers have identified a microRNA liver gene, miR-27b, which regulates lipid (cholesterol or fat) levels in the blood. The study found that miR-27b is sensitive to high triglycerides and is involved in lipid metabolism.
Researchers successfully created human brain cells from skin cells, which are highly effective in treating myelin disorders such as multiple sclerosis. The study opens the door to potential new treatments using these cells for neurological diseases characterized by the loss of myelin.
A Baylor University study found that people are more likely to continue behaving in ways that benefit their group, regardless of whether it's for the greater good. The researchers used public good experiments to show that conformity leads to positive feelings and attachments among group members.
Hyejin Moon's novel microfluidic devices improve accurate images and conditions of huge numbers of samples, enabling quicker disease biomarker identification. The technology has applications for speedier drug development and may lead to the development of devices used by patients in their own homes.
Surgeons have found improved surgical treatment for neurogenic thoracic outlet syndrome, a condition causing pain and numbness in the shoulder and arm. Adolescents tend to do better after surgery than adults, with significant improvements in symptoms and function.
Researchers found that sockeye salmon imprint on the magnetic field they experience when first entering the sea as juveniles, using it as a homing mechanism. This discovery has practical applications for predicting salmon distribution and understanding the impact of environmental changes on their navigation.
Researchers from University of Copenhagen identify Fbxl10 as crucial for embryonic stem cell differentiation and suggest it as a potential target for cancer therapy. The protein recruits Polycomb complexes to silence genes, maintaining cellular identity.
A study found that frequent dialysis can cause complications related to repeated access to the blood, including repair procedures and hospitalizations. The risk of these events was 76% higher with daily hemodialysis compared to conventional hemodialysis.
Researchers developed a computer tablet application to quantitatively measure neuromuscular performance in patients, tracking deviations from circular paths as a function of age, sex, and handedness. The technology may hold great potential to augment existing protocols in doctor's neuromotor assessment toolbox.
Researchers at EPFL have created a device that combines holographic microscopy and computational image processing to observe living biological tissues at the nanoscale. Three-dimensional images of living cells can be obtained in just a few minutes with an incredibly precise resolution of less than 100 nanometers.
Researchers from UAB have shown that gene therapy can cure type 1 diabetes in large animals with a single session. The therapy uses a 'glucose sensor' to regulate blood sugar levels, reducing diabetic hyperglycemia and preventing complications.
Researchers found that excess alpha-synuclein protein disrupts vital recycling processes in neurons, leading to progressive degeneration and cell death. The study provides a structural and mechanistic explanation for the progression of Parkinson's disease, shedding light on its causes and mechanisms.
A study published in Neurosurgery found that subcortical damage during awake craniotomy for brain tumor surgery can lead to worsening neurological deficits. The researchers analyzed data from 241 patients and found that 36 developed new neurological abnormalities while the surgeon was operating in the subcortex.
A large population-based cohort study of 7,500 men in Sweden found that permanent stress increases the risk of type 2 diabetes. The study showed that men who reported permanent stress had a significantly higher risk of developing diabetes compared to those with no or periodic stress.
Research found that a high intake of Southern-style foods, including fried chicken, bacon, and sugary drinks, was associated with a higher risk of stroke. In contrast, those who ate more fruits, vegetables, and whole grains had a lower risk of stroke.
Researchers at Johns Hopkins University have discovered a key protein that antidepressants and electroconvulsive therapy target to relieve depression by stimulating stem cells in the brain. This finding could lead to genetic tests to predict individual responses to therapy and develop new treatments.
Scientists have observed a rare pre-explosion outburst occurring just one month before a massive star underwent a supernova explosion. The findings validate a particular model predicting this type of event and provide insight into the processes taking place in the cores of such massive stars.
Researchers from Jena University warn of severe environmental damage in the Antarctic due to human activities such as vehicle tracks and building work. They suggest designating the Fildes Peninsula as an 'Antarctic Specially Managed Area' to reduce conflicting interests and protect the unique flora and fauna.
A large-scale study found that abnormal microRNA levels can be used to classify triple-negative breast cancer into four subtypes. The findings could lead to more effective therapies and personalized treatments for individual patients.
The study found that growing proportions of Harris County's Asian adults are now the U.S.-born children of Asian immigrants, and they are even better educated than their parents. This demographic shift suggests a changing face for the local Asian population in Houston.
A study published in PLOS Pathogens found that HIV exploits a human cytokine called interleukin 7 (IL-7) in semen to promote its own transmission. The researchers discovered that the increased concentration of IL-7 in semen facilitates HIV transmission to cervical tissue ex vivo.
Leading crowd work researchers propose a research agenda to enhance collaboration, incorporate AI, and create career paths for workers. The plan aims to make crowd work attractive for the best workers and thinkers, reducing exploitation and increasing rewards.
Two coronal mass ejections (CMEs) were observed by NASA's Solar Terrestrial Relations Observatory and Solar and Heliospheric Observatory, emitting solar particles into space at speeds of up to 750 miles per second. Historically, CMEs of this strength have caused minimal effects on Earth
A University of Missouri nursing informatics expert suggests that sophisticated IT leads to more efficient coordination of care and better protection of patient privacy. The study found that nursing homes with technology use more frequent face-to-face communication at the bedside, while those without IT rely on verbal cues or visual cues.
A minimally invasive surgical procedure to remove blood clots in brain tissue after hemorrhagic stroke appears safe and effective in improving long-term disability and reducing hospital time. The study found that patients treated with the surgery had less disability, spent less time in the hospital, and were less likely to be in a long...
Researchers found that healthy adults acquire a memory of microbes they've never encountered before, which could explain childhood vulnerability and vaccination effectiveness. This discovery challenges the long-held assumption that immune memory only develops upon exposure.
A recent study published in Cell Reports found that sunitinib, an anticancer drug, does not cause lingering risks for patients after their treatment ends. The research suggests that sunitinib works by slowing tumor growth and prolonging survival during treatment, without altering tumor biology after the drug is stopped.
The Hastings Center has released a special report on the evolving landscape of animal research ethics, citing examples of changes improving animal welfare and replacing animal testing. Alternative models, such as human cell-based toxicity testing, are gaining traction.
Researchers have created a nanostructure that manipulates electron waves to form plasmonic halos, offering control in light filtering and potential applications in biomedical plasmonics and discrete optical filtering. The unique structure allows for selective light transmission, creating an array of colored 'halos',
Researchers from Carnegie Museum of Natural History joined an international collaboration to create the most complete picture yet of placental mammals' evolution. The study combined molecular and morphological data on over 83 species, revealing new insights into their ancestry and shedding light on extinct species.
Scientists from Harvard Medical School and business innovators used a crowdsourcing platform to analyze vast amounts of genetic data, achieving unprecedented accuracy and speed. The study demonstrates the potential for combining basic science research with commercial sector expertise to solve complex problems.
A University of Toronto Scarborough researcher helped create a family tree of placental mammals, placing humans in the tree of life. The study used genetic and physical traits to conclude that placental mammals diversified much later than previously thought, with all major groups alive today originating after the dinosaurs' extinction.
Adding fruits and vegetables to the diet has been shown to reduce metabolic acidosis and kidney injury in late-stage chronic kidney disease patients. One-year plasma total carbon dioxide levels increased in both groups, indicating a lessening of metabolic acidosis.
The Gerontological Society of America has received a three-year grant to build upon its success in training geriatric social workers. The grant aims to establish a National Center on Gerontological Social Work Excellence, focusing on collaboration with the VA and mobilizing the HGSWI Alumni Network.
A new national poll conducted by Duke University found that 64% of Americans strongly support regulating greenhouse gas emissions and requiring utilities to switch to lower-carbon fuel sources. However, support for market-based approaches like cap-and-trade or a carbon tax is low, with only 29% in favor.
Researchers at ORNL have solved the mystery of how bacteria convert mercury into methylmercury, a far more toxic form. The team identified two genes, hgcA and hgcB, responsible for this conversion process, which has significant implications for protecting human health.